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The map label for this gene is cilA [H]

Identifier: 18310131

GI number: 18310131

Start: 1342512

End: 1344071

Strand: Direct

Name: cilA [H]

Synonym: CPE1149

Alternate gene names: 18310131

Gene position: 1342512-1344071 (Clockwise)

Preceding gene: 18310130

Following gene: 18310132

Centisome position: 44.29

GC content: 32.12

Gene sequence:

>1560_bases
ATGGGAATCAATAGTATCAATATAAATATACCAGATGACATATTAAAAGAGAGAAAAACTGTAGAATTTAAAGGAGAATT
CGCATTAGAACCTAAGGGAAATATTCAAGGAAGAAAAATAACAGCGACTTTTTGTGGAAAAAATAAAAAGTTATCATCTA
TAGCTGAATCTATAGAAAAAACAGGCCTTAAAGATGGTATGACTATATCTTTTCATCATCACTTCCGTGCTGGAGATTAT
ATTATTCGTATGGTTATGAAGGAAATTGCTAATCTTGGAATTAAGAATTTAAATCTTTGTGTAAGTTCTTTAACAAGTGC
TCATGAATTTTTAATAGATTATATAAAAGATGGCACAGTAACAGGAATAGAAACAAGTGGTATTCGTGGAAAACTAGGAG
AAGAAATTTCAAAAGGAATAATGAAAAAACCAGTAATTATTCGTTCTCATGGTGGACGTGCTCGTGCAATTGAGGCTGGT
GATACAAAGATAGATGTGGCCTTTTTAGGTGTTCCCTGTTCAGATGAATATGGAAATGCTAACGGAATACATGGAAAATC
TCAATGTGGTTCTTTAGGATATGCTATTATTGATTCTAAATATGCAGACAAGGTAGTTCTTATTACAGATACTATAATGC
CATATCCTAATGTACCAGCAAGTATTTCTCAACAGGATGTAGATTACATTGTGGAAGTTGAAGAAATAGGTGATCCAAAT
GGTATTGCTTCAGGGGCTACAAGATTTACAAAGGATCCTAAAGAGTTATTAATAGCAAAATATGCTTCCGCAGTAATTGA
AGCTTCTGGATATTTAAAAGATGGTTTTTCAATTCAAGCAGGTACAGGTGGAGCTTCCTTAGCAGTTGCTCGTTTCCTAA
AAGAGAAAATGGAAGAAAAAAATATAAAGGCAAGCTTTGGCCTTGGTGGAATAAGCAAACAATTTGTTGATTTACATGAA
GAAGGATTTATAGGAACATTATTTGATGTTCAAGGATTTGATTTAAAAGCTGTTGAATCCATTGGTAAGAATAATAAACA
TGTAGAAATAGATGCTTCTCTTTATGCAAATCCACATAATAAAGGATGCATTGCTAATAAATTAGACATAGTAATATTAA
GTGCTTTAGAAGTGGATAAAAACTTCAACGTAAATGTTATAACTGGTTCTGATGGTTATATAAGAGGGGCATCAGGTGGA
CACTCAGATACAGCTGCTGGTGCTAAATTATCAATGATAGTTTCTCCTTTAGTTCGTGGAAGAATACCAACAATAGTTGA
AAAGGTTAATACTGTAATAACCCCTGGGGAATCAATAGATGTCATTGTAACAGAACGTGGTGTTGCTATAAATGATAAAC
TTTCTAAGAATAAAGAGTTAAAAGAAAGATTAGAATCAAATAAAAATATTCCTATACTATCAATAGAAGAGCTTCATGAA
AAAGCTTTAAAAATTACAGGTACTCCAGAACCTATAAAATATGAAGATAGAGTTGTTGGAATTGTTGAATATCGTGATGG
TTCAATAATAGATGTTATACACAAGGTTAAAGAGGATTAA

Upstream 100 bases:

>100_bases
TAATGGAAAAATGATTGATAAGCCAGTAATAGCAAGGGCAGAAAGAGTTCTTATGCTAGCTAAGGCTTCAGGAATATCAT
ATGAAAAGGAAGTGTAATTT

Downstream 100 bases:

>100_bases
AAATTAAGAGGATAAAAAATGAACGAAAAGAATAAATTTTTGATAGAAATATTAAAAGGCAGAGAAGAAAGAGCATTTGA
AATAAAAAAACTAAATGAAA

Product: citrate lyase alpha subunit

Products: NA

Alternate protein names: Citrase alpha chain; Citrate (pro-3S)-lyase alpha chain; Citrate CoA-transferase subunit [H]

Number of amino acids: Translated: 519; Mature: 518

Protein sequence:

>519_residues
MGINSININIPDDILKERKTVEFKGEFALEPKGNIQGRKITATFCGKNKKLSSIAESIEKTGLKDGMTISFHHHFRAGDY
IIRMVMKEIANLGIKNLNLCVSSLTSAHEFLIDYIKDGTVTGIETSGIRGKLGEEISKGIMKKPVIIRSHGGRARAIEAG
DTKIDVAFLGVPCSDEYGNANGIHGKSQCGSLGYAIIDSKYADKVVLITDTIMPYPNVPASISQQDVDYIVEVEEIGDPN
GIASGATRFTKDPKELLIAKYASAVIEASGYLKDGFSIQAGTGGASLAVARFLKEKMEEKNIKASFGLGGISKQFVDLHE
EGFIGTLFDVQGFDLKAVESIGKNNKHVEIDASLYANPHNKGCIANKLDIVILSALEVDKNFNVNVITGSDGYIRGASGG
HSDTAAGAKLSMIVSPLVRGRIPTIVEKVNTVITPGESIDVIVTERGVAINDKLSKNKELKERLESNKNIPILSIEELHE
KALKITGTPEPIKYEDRVVGIVEYRDGSIIDVIHKVKED

Sequences:

>Translated_519_residues
MGINSININIPDDILKERKTVEFKGEFALEPKGNIQGRKITATFCGKNKKLSSIAESIEKTGLKDGMTISFHHHFRAGDY
IIRMVMKEIANLGIKNLNLCVSSLTSAHEFLIDYIKDGTVTGIETSGIRGKLGEEISKGIMKKPVIIRSHGGRARAIEAG
DTKIDVAFLGVPCSDEYGNANGIHGKSQCGSLGYAIIDSKYADKVVLITDTIMPYPNVPASISQQDVDYIVEVEEIGDPN
GIASGATRFTKDPKELLIAKYASAVIEASGYLKDGFSIQAGTGGASLAVARFLKEKMEEKNIKASFGLGGISKQFVDLHE
EGFIGTLFDVQGFDLKAVESIGKNNKHVEIDASLYANPHNKGCIANKLDIVILSALEVDKNFNVNVITGSDGYIRGASGG
HSDTAAGAKLSMIVSPLVRGRIPTIVEKVNTVITPGESIDVIVTERGVAINDKLSKNKELKERLESNKNIPILSIEELHE
KALKITGTPEPIKYEDRVVGIVEYRDGSIIDVIHKVKED
>Mature_518_residues
GINSININIPDDILKERKTVEFKGEFALEPKGNIQGRKITATFCGKNKKLSSIAESIEKTGLKDGMTISFHHHFRAGDYI
IRMVMKEIANLGIKNLNLCVSSLTSAHEFLIDYIKDGTVTGIETSGIRGKLGEEISKGIMKKPVIIRSHGGRARAIEAGD
TKIDVAFLGVPCSDEYGNANGIHGKSQCGSLGYAIIDSKYADKVVLITDTIMPYPNVPASISQQDVDYIVEVEEIGDPNG
IASGATRFTKDPKELLIAKYASAVIEASGYLKDGFSIQAGTGGASLAVARFLKEKMEEKNIKASFGLGGISKQFVDLHEE
GFIGTLFDVQGFDLKAVESIGKNNKHVEIDASLYANPHNKGCIANKLDIVILSALEVDKNFNVNVITGSDGYIRGASGGH
SDTAAGAKLSMIVSPLVRGRIPTIVEKVNTVITPGESIDVIVTERGVAINDKLSKNKELKERLESNKNIPILSIEELHEK
ALKITGTPEPIKYEDRVVGIVEYRDGSIIDVIHKVKED

Specific function: Represents a citrate:acetyl-ACP transferase [H]

COG id: COG3051

COG function: function code C; Citrate lyase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786832, Length=493, Percent_Identity=54.3610547667343, Blast_Score=555, Evalue=1e-159,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006472 [H]

Pfam domain/function: PF04223 CitF [H]

EC number: =4.1.3.6; =2.8.3.10 [H]

Molecular weight: Translated: 56140; Mature: 56009

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGINSININIPDDILKERKTVEFKGEFALEPKGNIQGRKITATFCGKNKKLSSIAESIEK
CCCCEEEECCCHHHHHCCCEEEECCEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHH
TGLKDGMTISFHHHFRAGDYIIRMVMKEIANLGIKNLNLCVSSLTSAHEFLIDYIKDGTV
CCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEE
TGIETSGIRGKLGEEISKGIMKKPVIIRSHGGRARAIEAGDTKIDVAFLGVPCSDEYGNA
EEEECCCCCCHHHHHHHHHHHHCCEEEECCCCCEEEEECCCCEEEEEEEECCCCCCCCCC
NGIHGKSQCGSLGYAIIDSKYADKVVLITDTIMPYPNVPASISQQDVDYIVEVEEIGDPN
CCCCCCHHCCCCCEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCC
GIASGATRFTKDPKELLIAKYASAVIEASGYLKDGFSIQAGTGGASLAVARFLKEKMEEK
CCCCCCHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHC
NIKASFGLGGISKQFVDLHEEGFIGTLFDVQGFDLKAVESIGKNNKHVEIDASLYANPHN
CCEEECCCCCCHHHHHHHHCCCCEEEEEECCCCCHHHHHHHCCCCCEEEEEEEEEECCCC
KGCIANKLDIVILSALEVDKNFNVNVITGSDGYIRGASGGHSDTAAGAKLSMIVSPLVRG
CCCCCCCCEEEEEEEEEECCCCCEEEEECCCCEEECCCCCCCCCCCCCHHHHHHHHHHHC
RIPTIVEKVNTVITPGESIDVIVTERGVAINDKLSKNKELKERLESNKNIPILSIEELHE
CCHHHHHHHHHEECCCCCEEEEEECCCEEECCHHCCCHHHHHHHHCCCCCCEEEHHHHHH
KALKITGTPEPIKYEDRVVGIVEYRDGSIIDVIHKVKED
HHEEECCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHCC
>Mature Secondary Structure 
GINSININIPDDILKERKTVEFKGEFALEPKGNIQGRKITATFCGKNKKLSSIAESIEK
CCCEEEECCCHHHHHCCCEEEECCEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHH
TGLKDGMTISFHHHFRAGDYIIRMVMKEIANLGIKNLNLCVSSLTSAHEFLIDYIKDGTV
CCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEE
TGIETSGIRGKLGEEISKGIMKKPVIIRSHGGRARAIEAGDTKIDVAFLGVPCSDEYGNA
EEEECCCCCCHHHHHHHHHHHHCCEEEECCCCCEEEEECCCCEEEEEEEECCCCCCCCCC
NGIHGKSQCGSLGYAIIDSKYADKVVLITDTIMPYPNVPASISQQDVDYIVEVEEIGDPN
CCCCCCHHCCCCCEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCC
GIASGATRFTKDPKELLIAKYASAVIEASGYLKDGFSIQAGTGGASLAVARFLKEKMEEK
CCCCCCHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHC
NIKASFGLGGISKQFVDLHEEGFIGTLFDVQGFDLKAVESIGKNNKHVEIDASLYANPHN
CCEEECCCCCCHHHHHHHHCCCCEEEEEECCCCCHHHHHHHCCCCCEEEEEEEEEECCCC
KGCIANKLDIVILSALEVDKNFNVNVITGSDGYIRGASGGHSDTAAGAKLSMIVSPLVRG
CCCCCCCCEEEEEEEEEECCCCCEEEEECCCCEEECCCCCCCCCCCCCHHHHHHHHHHHC
RIPTIVEKVNTVITPGESIDVIVTERGVAINDKLSKNKELKERLESNKNIPILSIEELHE
CCHHHHHHHHHEECCCCCEEEEEECCCEEECCHHCCCHHHHHHHHCCCCCCEEEHHHHHH
KALKITGTPEPIKYEDRVVGIVEYRDGSIIDVIHKVKED
HHEEECCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9457870 [H]