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The map label for this gene is sstT [H]

Identifier: 18309949

GI number: 18309949

Start: 1164789

End: 1165952

Strand: Direct

Name: sstT [H]

Synonym: CPE0967

Alternate gene names: 18309949

Gene position: 1164789-1165952 (Clockwise)

Preceding gene: 18309948

Following gene: 18309950

Centisome position: 38.42

GC content: 30.67

Gene sequence:

>1164_bases
GTGAAGAAATTATTTAATAATCTTATTTTTAAACTTGTTTTAGGTGTTATATTAGGAATAATAATAGGCACATACTCTTC
AGAGGGGCTTATGTCAACAATTGTGACAATTAAGTATGTATTGGGACAAATTATATTTTTCTCTGTTCCACTTATTATTT
TAGGATTTATAGCTCCATCTATTGCTAAATTAAAAGATAACGCAAGCAAACTATTAGGATATGCTGTTTTAATAGCTTAT
TTATCTTCAGTTTTTGCTGCTATTCTTTCAATGATTGCAGGATATGCATTAATACCTAAATTATCTATAGTATCTAATAT
AGCATCATTAAAGGAATTACCAGAACTTATATTTAAATTAGATATACCACCAGTTATGAGTGTAATGAGTGCGTTAGCTT
TAGCATTACTTTTAGGATTAGCTGTTGGATGGACAAAGGCTGATTTAGTAGAAAAGCTTTTAGATCAATTTCAAGCTATA
GTACTTAGTATTGTAAATAAAATAATAATACCAATATTACCATTTTTCATAGCAACTAACTTTGCAGCTTTAGCGTATGA
AGGAGGATTAAGTAATCAACTTCCTGTATTCTTTAAAGTTATATTAATTGTATTATTTGGTCATTTTATATGGTTAACAA
TTTTATATTTAATAGGTGGAGCAATATCAAAAGAAAATCCATGGGAAGTTGTAAAATACTATGGACCAGCGTATCTTACT
GCTGTTGGTACAATGTCAAGTGCAGCAACATTACCAGTAGCTTTAGAGTCTGCAAAGAAATCAAAGGCTTTAAGAGAAGA
TATAGTGGATTTTGCAATACCATTATGTTCAAACATACATTTATGTGGTTCAGTTCTTACAGAAGTATTTTTTGTAATGA
CAGTATCTCAAATTTTATATGGTAAGATTCCTAGTTTACCAACTATGATATTGTTTATAGTATTATTAGGAGTATTCGCA
ATAGGGGCACCAGGAGTCCCAGGTGGTACAGTAATGGCATCATTAGGTTTAATAATTAGTGTATTAGCCTTTGATGAGGC
TGGGACAGCTCTTATGTTAACAATATTTGCTCTTCAAGATAGTTTTGGAACAGCATGTAATGTAACTGGGGATGGAGCAA
TAGCTCTTATGCTGACAGGTATAGCAAAGAAAAAGAATTTATAA

Upstream 100 bases:

>100_bases
CCGTGGAATTTTACTTCTGCCTCTGTATAGGGGGTAGAAGTTTTTTTATTTATAAATAATTCTTTACATGAAAGTATTAA
ATAAAAAGGGGGGATAAATT

Downstream 100 bases:

>100_bases
GACAAAAAGGTGTACTTTTATAGTACGCCTTTTTATTTTTAATTAAATAATAGGGAGTATACATGAAATTAAGGTGATAA
AAATAATCACTTTAAATCAA

Product: glutamate/ aspartate transporter

Products: orotate [Cytoplasm]; fumarate [Cytoplasm]; malate [Cytoplasm]; Na (I) [Cytoplasm]; succinate [Cytoplasm] [C]

Alternate protein names: Na(+)/serine-threonine symporter [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MKKLFNNLIFKLVLGVILGIIIGTYSSEGLMSTIVTIKYVLGQIIFFSVPLIILGFIAPSIAKLKDNASKLLGYAVLIAY
LSSVFAAILSMIAGYALIPKLSIVSNIASLKELPELIFKLDIPPVMSVMSALALALLLGLAVGWTKADLVEKLLDQFQAI
VLSIVNKIIIPILPFFIATNFAALAYEGGLSNQLPVFFKVILIVLFGHFIWLTILYLIGGAISKENPWEVVKYYGPAYLT
AVGTMSSAATLPVALESAKKSKALREDIVDFAIPLCSNIHLCGSVLTEVFFVMTVSQILYGKIPSLPTMILFIVLLGVFA
IGAPGVPGGTVMASLGLIISVLAFDEAGTALMLTIFALQDSFGTACNVTGDGAIALMLTGIAKKKNL

Sequences:

>Translated_387_residues
MKKLFNNLIFKLVLGVILGIIIGTYSSEGLMSTIVTIKYVLGQIIFFSVPLIILGFIAPSIAKLKDNASKLLGYAVLIAY
LSSVFAAILSMIAGYALIPKLSIVSNIASLKELPELIFKLDIPPVMSVMSALALALLLGLAVGWTKADLVEKLLDQFQAI
VLSIVNKIIIPILPFFIATNFAALAYEGGLSNQLPVFFKVILIVLFGHFIWLTILYLIGGAISKENPWEVVKYYGPAYLT
AVGTMSSAATLPVALESAKKSKALREDIVDFAIPLCSNIHLCGSVLTEVFFVMTVSQILYGKIPSLPTMILFIVLLGVFA
IGAPGVPGGTVMASLGLIISVLAFDEAGTALMLTIFALQDSFGTACNVTGDGAIALMLTGIAKKKNL
>Mature_387_residues
MKKLFNNLIFKLVLGVILGIIIGTYSSEGLMSTIVTIKYVLGQIIFFSVPLIILGFIAPSIAKLKDNASKLLGYAVLIAY
LSSVFAAILSMIAGYALIPKLSIVSNIASLKELPELIFKLDIPPVMSVMSALALALLLGLAVGWTKADLVEKLLDQFQAI
VLSIVNKIIIPILPFFIATNFAALAYEGGLSNQLPVFFKVILIVLFGHFIWLTILYLIGGAISKENPWEVVKYYGPAYLT
AVGTMSSAATLPVALESAKKSKALREDIVDFAIPLCSNIHLCGSVLTEVFFVMTVSQILYGKIPSLPTMILFIVLLGVFA
IGAPGVPGGTVMASLGLIISVLAFDEAGTALMLTIFALQDSFGTACNVTGDGAIALMLTGIAKKKNL

Specific function: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) [H]

COG id: COG1301

COG function: function code C; Na+/H+-dicarboxylate symporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Caenorhabditis elegans, GI71996953, Length=273, Percent_Identity=25.2747252747253, Blast_Score=68, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI193206505, Length=164, Percent_Identity=30.4878048780488, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991
- InterPro:   IPR023025 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 41225; Mature: 41225

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLFNNLIFKLVLGVILGIIIGTYSSEGLMSTIVTIKYVLGQIIFFSVPLIILGFIAPS
CHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAKLKDNASKLLGYAVLIAYLSSVFAAILSMIAGYALIPKLSIVSNIASLKELPELIFKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DIPPVMSVMSALALALLLGLAVGWTKADLVEKLLDQFQAIVLSIVNKIIIPILPFFIATN
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAALAYEGGLSNQLPVFFKVILIVLFGHFIWLTILYLIGGAISKENPWEVVKYYGPAYLT
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHH
AVGTMSSAATLPVALESAKKSKALREDIVDFAIPLCSNIHLCGSVLTEVFFVMTVSQILY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
GKIPSLPTMILFIVLLGVFAIGAPGVPGGTVMASLGLIISVLAFDEAGTALMLTIFALQD
CCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
SFGTACNVTGDGAIALMLTGIAKKKNL
CCCCEECCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKLFNNLIFKLVLGVILGIIIGTYSSEGLMSTIVTIKYVLGQIIFFSVPLIILGFIAPS
CHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAKLKDNASKLLGYAVLIAYLSSVFAAILSMIAGYALIPKLSIVSNIASLKELPELIFKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DIPPVMSVMSALALALLLGLAVGWTKADLVEKLLDQFQAIVLSIVNKIIIPILPFFIATN
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAALAYEGGLSNQLPVFFKVILIVLFGHFIWLTILYLIGGAISKENPWEVVKYYGPAYLT
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHH
AVGTMSSAATLPVALESAKKSKALREDIVDFAIPLCSNIHLCGSVLTEVFFVMTVSQILY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
GKIPSLPTMILFIVLLGVFAIGAPGVPGGTVMASLGLIISVLAFDEAGTALMLTIFALQD
CCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
SFGTACNVTGDGAIALMLTGIAKKKNL
CCCCEECCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: orotate [Periplasm]; fumarate [Periplasm]; malate [Periplasm]; Na (I) [Periplasm]; succinate [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + orotate [Periplasm] = Na (I) [Cytoplasm] + orotate [Cytoplasm] Na (I) [Periplasm] + fumarate [Periplasm] = Na (I) [Cytoplasm] + fumarate [Cytoplasm] Na (I) [Periplasm] + malate [Periplasm] = Na (I) [Cytoplasm] + malate [Cytoplasm] Na

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA