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The map label for this gene is manX [H]

Identifier: 18309803

GI number: 18309803

Start: 1006099

End: 1007079

Strand: Direct

Name: manX [H]

Synonym: CPE0821

Alternate gene names: 18309803

Gene position: 1006099-1007079 (Clockwise)

Preceding gene: 18309802

Following gene: 18309804

Centisome position: 33.19

GC content: 35.88

Gene sequence:

>981_bases
ATGGTAGGAATTATTCTTGCTAGTCATGGGGAATTTGCTAAAGGCATATTACAATCTGGCTCAATGATTTTTGGAGAACA
GGAAAATGTAAAAGCTGTTACATTAATGCCGAGTGAAGGACCTGATGATATTAGAGCAAAAATGAAAGAAGCAATCGCTT
CCTTTGATAATCAAGATGAGGTTTTATTCTTAGTTGATCTATGGGGTGGAACACCATTTAACCAAGCAGATAGCCTAGTT
GAAGAACATAAAGACAAATGGGCAATCGTAGCTGGTATGAATTTACCAATGGTTATTGAAGCTTATGCTTCTCGTTTCTC
AATGGAATCAGCACAAGAAATTGCTGCTAATATCCTAAAGTCAGCTAGAGAAGGAGTTAAAGTTAAGCCTGAATCATTAG
AACCTGAAGAGTCTACTAAAGCTACTACAGATTCTGTTCAACAATCTAACAATGTAGGTGCGCCTGGCTCTTTTGAATAC
GTTTTGGCACGTATTGATTCACGTTTACTTCATGGTCAAGTAGCAACTGCTTGGACAAAAACTGTAAAACCAACAAGAAT
TATTGTTGTATCAGACGATGTAGCTAAAGATGAACTTCGTAAGAAATTGATTCAACAAGCAGCTCCTCCTGGAGTTAAAG
CGCATACTGTTCCAGTTAGTCAAATGATTAAGCTTGCAAAAGATGATCAACACTTTGGAGGACAGCGTGCATTACTTCTT
TTTGAAAACCCAGAAGATGTACTTAGAGCAGTAGAGGGAGGAGTACCTATAAAGACAGTTAATGTTGGTTCTATGGCTCA
CTCTCCAGGTAAGGTTCAACCAAATAAAGTACTTGCTTTTAATCAAGAAGATATTGACACTTTTAATAAACTTAAAGAAG
CTGGATTAGATTTTGATGTTCGTAAAGTTCCAAATGATACAAAAGGAAATATGGATGAAATTCTTAAAAAAGCACAAGAG
GAATTAAATAAATTAAAATAA

Upstream 100 bases:

>100_bases
ATTTACATAAGGCTTGTAAAACTGATGTAAAAATTGTAAAATTAACGTAAGATAAAGTGAAAAATTTGTCTTAAAGAATA
AAAAAATAGGAGGTATACAT

Downstream 100 bases:

>100_bases
TTTGATTTAATATAAATAAGTTATTTTAATGAAAAGGAGGATTAATAACAGTGGATTTAAATATAATTCAAATAATATTA
GTTATTATTATTGCATTCTT

Product: PTS system

Products: NA

Alternate protein names: EIIAB-Man; Mannose-specific phosphotransferase enzyme IIA component; EIII-Man; PTS system mannose-specific EIIA component; Mannose-specific phosphotransferase enzyme IIB component; PTS system mannose-specific EIIB component [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MVGIILASHGEFAKGILQSGSMIFGEQENVKAVTLMPSEGPDDIRAKMKEAIASFDNQDEVLFLVDLWGGTPFNQADSLV
EEHKDKWAIVAGMNLPMVIEAYASRFSMESAQEIAANILKSAREGVKVKPESLEPEESTKATTDSVQQSNNVGAPGSFEY
VLARIDSRLLHGQVATAWTKTVKPTRIIVVSDDVAKDELRKKLIQQAAPPGVKAHTVPVSQMIKLAKDDQHFGGQRALLL
FENPEDVLRAVEGGVPIKTVNVGSMAHSPGKVQPNKVLAFNQEDIDTFNKLKEAGLDFDVRKVPNDTKGNMDEILKKAQE
ELNKLK

Sequences:

>Translated_326_residues
MVGIILASHGEFAKGILQSGSMIFGEQENVKAVTLMPSEGPDDIRAKMKEAIASFDNQDEVLFLVDLWGGTPFNQADSLV
EEHKDKWAIVAGMNLPMVIEAYASRFSMESAQEIAANILKSAREGVKVKPESLEPEESTKATTDSVQQSNNVGAPGSFEY
VLARIDSRLLHGQVATAWTKTVKPTRIIVVSDDVAKDELRKKLIQQAAPPGVKAHTVPVSQMIKLAKDDQHFGGQRALLL
FENPEDVLRAVEGGVPIKTVNVGSMAHSPGKVQPNKVLAFNQEDIDTFNKLKEAGLDFDVRKVPNDTKGNMDEILKKAQE
ELNKLK
>Mature_326_residues
MVGIILASHGEFAKGILQSGSMIFGEQENVKAVTLMPSEGPDDIRAKMKEAIASFDNQDEVLFLVDLWGGTPFNQADSLV
EEHKDKWAIVAGMNLPMVIEAYASRFSMESAQEIAANILKSAREGVKVKPESLEPEESTKATTDSVQQSNNVGAPGSFEY
VLARIDSRLLHGQVATAWTKTVKPTRIIVVSDDVAKDELRKKLIQQAAPPGVKAHTVPVSQMIKLAKDDQHFGGQRALLL
FENPEDVLRAVEGGVPIKTVNVGSMAHSPGKVQPNKVLAFNQEDIDTFNKLKEAGLDFDVRKVPNDTKGNMDEILKKAQE
ELNKLK

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG3444

COG function: function code G; Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-4 domain [H]

Homologues:

Organism=Escherichia coli, GI1788120, Length=320, Percent_Identity=41.5625, Blast_Score=247, Evalue=7e-67,
Organism=Escherichia coli, GI87082217, Length=157, Percent_Identity=33.7579617834395, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1789527, Length=151, Percent_Identity=33.7748344370861, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2880 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 260 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004701
- InterPro:   IPR004720 [H]

Pfam domain/function: PF03610 EIIA-man; PF03830 PTSIIB_sorb [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 35640; Mature: 35640

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS51096 PTS_EIIA_TYPE_4 ; PS51101 PTS_EIIB_TYPE_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGIILASHGEFAKGILQSGSMIFGEQENVKAVTLMPSEGPDDIRAKMKEAIASFDNQDE
CEEEEEECCCHHHHHHHHCCCEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCC
VLFLVDLWGGTPFNQADSLVEEHKDKWAIVAGMNLPMVIEAYASRFSMESAQEIAANILK
EEEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCHHHHHHHHHHHHH
SAREGVKVKPESLEPEESTKATTDSVQQSNNVGAPGSFEYVLARIDSRLLHGQVATAWTK
HHHCCCEECCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHH
TVKPTRIIVVSDDVAKDELRKKLIQQAAPPGVKAHTVPVSQMIKLAKDDQHFGGQRALLL
CCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHCCCCCCCCCEEEEE
FENPEDVLRAVEGGVPIKTVNVGSMAHSPGKVQPNKVLAFNQEDIDTFNKLKEAGLDFDV
ECCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCH
RKVPNDTKGNMDEILKKAQEELNKLK
HCCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVGIILASHGEFAKGILQSGSMIFGEQENVKAVTLMPSEGPDDIRAKMKEAIASFDNQDE
CEEEEEECCCHHHHHHHHCCCEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCC
VLFLVDLWGGTPFNQADSLVEEHKDKWAIVAGMNLPMVIEAYASRFSMESAQEIAANILK
EEEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCHHHHHHHHHHHHH
SAREGVKVKPESLEPEESTKATTDSVQQSNNVGAPGSFEYVLARIDSRLLHGQVATAWTK
HHHCCCEECCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHH
TVKPTRIIVVSDDVAKDELRKKLIQQAAPPGVKAHTVPVSQMIKLAKDDQHFGGQRALLL
CCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHCCCCCCCCCEEEEE
FENPEDVLRAVEGGVPIKTVNVGSMAHSPGKVQPNKVLAFNQEDIDTFNKLKEAGLDFDV
ECCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCH
RKVPNDTKGNMDEILKKAQEELNKLK
HCCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA