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The map label for this gene is nanM [H]

Identifier: 18309708

GI number: 18309708

Start: 903129

End: 904283

Strand: Direct

Name: nanM [H]

Synonym: CPE0726

Alternate gene names: 18309708

Gene position: 903129-904283 (Clockwise)

Preceding gene: 18309707

Following gene: 18309709

Centisome position: 29.79

GC content: 30.65

Gene sequence:

>1155_bases
ATGAAAAAGATATGGAAGTATGGGGTACTACTTGCATTACCATTAGTTTTAGCTGGATGTGGAAATAAGCCTGCAGAGGA
TAGTAATAAAAATAAGGAAATTACTTCAATTAAGTGGACTGTTGATGGAGAGTTAGAAGCTCAAAAAGGTCAAAGCAAAA
ATATAGGAACAGCAGGTTTACTTTATGGTAAAACAAAAGATTATATAGTTGTGGGAGGTGGAGCAAACTTTCCAGAGGAG
CCAGTGGCAAAAGGAGGAGCTAAAAAGCTTTATCCTGATATATATGTATTAAAAAATGAAAATGGAGATTTAAAGCAAGT
AGATCATACAACATTAGATTATGAAATAGGGTATGGAAGTTCAATAACTACTGAGGAAGGAATTTATTATGTAGGTGGAA
GCCCTAATAAAGAAGAAGGAAATAACGTTTCTCTTATTACAACTGATGAAAAAGGTAAAATTGGTTTAAAGCATATTGGA
GATTTACCTTTTACATTTAGTGATGGCTTTGCAGTTAAAAAAGATAAAGATATTTATTTAGGACTTGGAAAACAAGATGG
AAAAGCTAGTAATAAGGTTTATAAATTTAATGTTGAAACAGGAAAAACAGAAGAATTAAAGGAAATACCAGGAGAACCTA
CTAGAAATCAAGCTGTTGCTCAATTATTAGGTGATGATATATACGTATTTAGTGGTGGAGATAAAATTGCTTACACAGAT
GGTTATAAATATAGCATTAAAGATAATTCATGGACTCAAGTAGCTGACGTTAAAATAGGAAATGAAGAAATTTCACTTTT
AGGTGCTAATTCAGTTAAATTAAATGAAGATGAAATGCTTGTTATAGGTGGATTTAATAAAGCAGTTTATGATGATGCTG
TAAAAAACTTAAACACACTAAAAGATGAAAGTCTAGCTGAATTTAAGAAAGAGTATTTTGGAAGAGACCCTCAAGATTTT
GCTTGGAATACAAAAGTACTAATTTATAACTCAAAAAATAATGAGTGGAAGTCAATTGGAGATGTACCATTTAATGCTCC
ATGTGGAGAAGCATTAATATTAGATGGAGATAATATCTTCTCAATAAATGGAGAAATCAAACCAGGAATTAGAACAAATA
AAATTTACTCAGGTGAATTAATCTATAAAAAGTAA

Upstream 100 bases:

>100_bases
TGTCTTATATTGAAATGAATTTAAAATATTTAGAGAGTGGAGCTAATAAATAAGAAATTATTAAAAATATTATTTTATGG
TTTGAAAGGGGTAAAAGATT

Downstream 100 bases:

>100_bases
ATAAAATGAGAGTGAAAAAATAAACAAAATAGGCGTGTATCAAAATATAATAAAACTTACAGCTATTTTTAATAGGTATT
AAATTAGCTTTAGAATATTT

Product: hypothetical protein

Products: NA

Alternate protein names: N-acetylneuraminate mutarotase; Neu5Ac mutarotase; Sialic acid epimerase [H]

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MKKIWKYGVLLALPLVLAGCGNKPAEDSNKNKEITSIKWTVDGELEAQKGQSKNIGTAGLLYGKTKDYIVVGGGANFPEE
PVAKGGAKKLYPDIYVLKNENGDLKQVDHTTLDYEIGYGSSITTEEGIYYVGGSPNKEEGNNVSLITTDEKGKIGLKHIG
DLPFTFSDGFAVKKDKDIYLGLGKQDGKASNKVYKFNVETGKTEELKEIPGEPTRNQAVAQLLGDDIYVFSGGDKIAYTD
GYKYSIKDNSWTQVADVKIGNEEISLLGANSVKLNEDEMLVIGGFNKAVYDDAVKNLNTLKDESLAEFKKEYFGRDPQDF
AWNTKVLIYNSKNNEWKSIGDVPFNAPCGEALILDGDNIFSINGEIKPGIRTNKIYSGELIYKK

Sequences:

>Translated_384_residues
MKKIWKYGVLLALPLVLAGCGNKPAEDSNKNKEITSIKWTVDGELEAQKGQSKNIGTAGLLYGKTKDYIVVGGGANFPEE
PVAKGGAKKLYPDIYVLKNENGDLKQVDHTTLDYEIGYGSSITTEEGIYYVGGSPNKEEGNNVSLITTDEKGKIGLKHIG
DLPFTFSDGFAVKKDKDIYLGLGKQDGKASNKVYKFNVETGKTEELKEIPGEPTRNQAVAQLLGDDIYVFSGGDKIAYTD
GYKYSIKDNSWTQVADVKIGNEEISLLGANSVKLNEDEMLVIGGFNKAVYDDAVKNLNTLKDESLAEFKKEYFGRDPQDF
AWNTKVLIYNSKNNEWKSIGDVPFNAPCGEALILDGDNIFSINGEIKPGIRTNKIYSGELIYKK
>Mature_384_residues
MKKIWKYGVLLALPLVLAGCGNKPAEDSNKNKEITSIKWTVDGELEAQKGQSKNIGTAGLLYGKTKDYIVVGGGANFPEE
PVAKGGAKKLYPDIYVLKNENGDLKQVDHTTLDYEIGYGSSITTEEGIYYVGGSPNKEEGNNVSLITTDEKGKIGLKHIG
DLPFTFSDGFAVKKDKDIYLGLGKQDGKASNKVYKFNVETGKTEELKEIPGEPTRNQAVAQLLGDDIYVFSGGDKIAYTD
GYKYSIKDNSWTQVADVKIGNEEISLLGANSVKLNEDEMLVIGGFNKAVYDDAVKNLNTLKDESLAEFKKEYFGRDPQDF
AWNTKVLIYNSKNNEWKSIGDVPFNAPCGEALILDGDNIFSINGEIKPGIRTNKIYSGELIYKK

Specific function: Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, whic

COG id: COG3055

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 7 Kelch repeats [H]

Homologues:

Organism=Escherichia coli, GI87082419, Length=226, Percent_Identity=26.9911504424779, Blast_Score=92, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013089
- InterPro:   IPR015915
- InterPro:   IPR006652
- InterPro:   IPR019936 [H]

Pfam domain/function: PF01344 Kelch_1 [H]

EC number: NA

Molecular weight: Translated: 42184; Mature: 42184

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIWKYGVLLALPLVLAGCGNKPAEDSNKNKEITSIKWTVDGELEAQKGQSKNIGTAGL
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCCEEECCCCCCCCCCEEE
LYGKTKDYIVVGGGANFPEEPVAKGGAKKLYPDIYVLKNENGDLKQVDHTTLDYEIGYGS
EECCCCCEEEECCCCCCCCCHHHCCCCCCCCCEEEEEECCCCCEEECCCEEEEEEECCCC
SITTEEGIYYVGGSPNKEEGNNVSLITTDEKGKIGLKHIGDLPFTFSDGFAVKKDKDIYL
CCCCCCCEEEECCCCCCCCCCEEEEEEECCCCCCCHHHCCCCCEEECCCEEEECCCEEEE
GLGKQDGKASNKVYKFNVETGKTEELKEIPGEPTRNQAVAQLLGDDIYVFSGGDKIAYTD
EECCCCCCCCCCEEEEECCCCCHHHHHHCCCCCCHHHHHHHHHCCCEEEEECCCEEEEEC
GYKYSIKDNSWTQVADVKIGNEEISLLGANSVKLNEDEMLVIGGFNKAVYDDAVKNLNTL
CEEEEECCCCCEEEEEEEECCCEEEEEECCCEEECCCCEEEEECCCHHHHHHHHHHHHHH
KDESLAEFKKEYFGRDPQDFAWNTKVLIYNSKNNEWKSIGDVPFNAPCGEALILDGDNIF
CHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCEECCCCCCCCCCCEEEECCCCEE
SINGEIKPGIRTNKIYSGELIYKK
EECCEECCCCCCCEEECCEEEEEC
>Mature Secondary Structure
MKKIWKYGVLLALPLVLAGCGNKPAEDSNKNKEITSIKWTVDGELEAQKGQSKNIGTAGL
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCCEEECCCCCCCCCCEEE
LYGKTKDYIVVGGGANFPEEPVAKGGAKKLYPDIYVLKNENGDLKQVDHTTLDYEIGYGS
EECCCCCEEEECCCCCCCCCHHHCCCCCCCCCEEEEEECCCCCEEECCCEEEEEEECCCC
SITTEEGIYYVGGSPNKEEGNNVSLITTDEKGKIGLKHIGDLPFTFSDGFAVKKDKDIYL
CCCCCCCEEEECCCCCCCCCCEEEEEEECCCCCCCHHHCCCCCEEECCCEEEECCCEEEE
GLGKQDGKASNKVYKFNVETGKTEELKEIPGEPTRNQAVAQLLGDDIYVFSGGDKIAYTD
EECCCCCCCCCCEEEEECCCCCHHHHHHCCCCCCHHHHHHHHHCCCEEEEECCCEEEEEC
GYKYSIKDNSWTQVADVKIGNEEISLLGANSVKLNEDEMLVIGGFNKAVYDDAVKNLNTL
CEEEEECCCCCEEEEEEEECCCEEEEEECCCEEECCCCEEEEECCCHHHHHHHHHHHHHH
KDESLAEFKKEYFGRDPQDFAWNTKVLIYNSKNNEWKSIGDVPFNAPCGEALILDGDNIF
CHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCEECCCCCCCCCCCEEEECCCCEE
SINGEIKPGIRTNKIYSGELIYKK
EECCEECCCCCCCEEECCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA