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The map label for this gene is zupT

Identifier: 18309703

GI number: 18309703

Start: 896376

End: 897233

Strand: Direct

Name: zupT

Synonym: CPE0721

Alternate gene names: 18309703

Gene position: 896376-897233 (Clockwise)

Preceding gene: 18309702

Following gene: 18309704

Centisome position: 29.57

GC content: 31.59

Gene sequence:

>858_bases
ATGAAAGGAGGAGATAATATGAATAATGTACTTATGGCTTTTCTATTAACTTTATTAGCAGGATTAGCTACTGGAATAGG
AAGTTGCATAGCTTTTTTTGCAAAGAAGACTAATAAAAAGTTTTTATGTGTAAGTTTAGGTTTTTCTGCTGGAGTTATGA
TTTATGTTTCAATGATAGAAATGTTTCAAACAGCTAAGGAATCCCTTGTTGGGGTTATGGGTATTAAGGCAGGAAATTGG
ATTACTGTTATTTCATTCTTTGCTGGTATAGCAATAATTGCTTTAATAGATAAATTTGTACCTGAAGAAGAAAATCCTCA
TGAGGTTAGAAGTGTTGAAGAAGTGGAAAATGAAATTGAGGAATATAAAGGTGAAAATAAAGAGGGCAAAGCAGATATTA
AAGATAAAACTCTTATGAGAACAGGAATAGTTACGGCTTTAGCTATAGCCATACACAATTTCCCAGAAGGATTAGCTACC
TTTGTTTCTGCACTAGAAGGAGCAAGCTTAGCAATTCCAATAACTATTGCAATAGCAATTCATAATATACCAGAAGGAAT
ATCAGTATCAGTTCCTATTTTCTATGCTACTGGAGATAAAAAGAAAGCTTTTTTATATTCTTTCTTATCAGGTATGTCAG
AACCAATAGGAGCGATAATAGGATATACTTTATTAAGAAATATTTTTAATGATATAACTTTAGGAATATTATTATCAGCA
GTGGCTGGAATAATGGTTTTTATATCTTTAGATGAATTATTGCCAACAGCAAGAAAGTACGGGGAGCATCATTTGGCTAT
ATATGGTCTGATTGCAGGAATGGTTGTTATGGCAGTTAGTTTATTATTATTTATATAG

Upstream 100 bases:

>100_bases
CTTAAATAAGGTTTTATAGGAGAGAGGAATTAAATAAGTGGACAAATGCAGAGTTATAGTTTATAATTGAAAATAATTAT
CAATTGATTACGGAGTAAGT

Downstream 100 bases:

>100_bases
ATTAATTTAAACCTTCGTTGATTTAAAGAGCTATTTCAACGGAGGTTTTTATTCATTATTGCTTTTTCGAAAATAAAAGA
ATATAATAATAAATAAGAAT

Product: zinc transporter ZupT

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MKGGDNMNNVLMAFLLTLLAGLATGIGSCIAFFAKKTNKKFLCVSLGFSAGVMIYVSMIEMFQTAKESLVGVMGIKAGNW
ITVISFFAGIAIIALIDKFVPEEENPHEVRSVEEVENEIEEYKGENKEGKADIKDKTLMRTGIVTALAIAIHNFPEGLAT
FVSALEGASLAIPITIAIAIHNIPEGISVSVPIFYATGDKKKAFLYSFLSGMSEPIGAIIGYTLLRNIFNDITLGILLSA
VAGIMVFISLDELLPTARKYGEHHLAIYGLIAGMVVMAVSLLLFI

Sequences:

>Translated_285_residues
MKGGDNMNNVLMAFLLTLLAGLATGIGSCIAFFAKKTNKKFLCVSLGFSAGVMIYVSMIEMFQTAKESLVGVMGIKAGNW
ITVISFFAGIAIIALIDKFVPEEENPHEVRSVEEVENEIEEYKGENKEGKADIKDKTLMRTGIVTALAIAIHNFPEGLAT
FVSALEGASLAIPITIAIAIHNIPEGISVSVPIFYATGDKKKAFLYSFLSGMSEPIGAIIGYTLLRNIFNDITLGILLSA
VAGIMVFISLDELLPTARKYGEHHLAIYGLIAGMVVMAVSLLLFI
>Mature_285_residues
MKGGDNMNNVLMAFLLTLLAGLATGIGSCIAFFAKKTNKKFLCVSLGFSAGVMIYVSMIEMFQTAKESLVGVMGIKAGNW
ITVISFFAGIAIIALIDKFVPEEENPHEVRSVEEVENEIEEYKGENKEGKADIKDKTLMRTGIVTALAIAIHNFPEGLAT
FVSALEGASLAIPITIAIAIHNIPEGISVSVPIFYATGDKKKAFLYSFLSGMSEPIGAIIGYTLLRNIFNDITLGILLSA
VAGIMVFISLDELLPTARKYGEHHLAIYGLIAGMVVMAVSLLLFI

Specific function: Mediates zinc uptake. May also transport other divalent cations

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily

Homologues:

Organism=Homo sapiens, GI229577418, Length=327, Percent_Identity=28.4403669724771, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI229577422, Length=334, Percent_Identity=28.1437125748503, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1789419, Length=273, Percent_Identity=34.0659340659341, Blast_Score=151, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI17507805, Length=315, Percent_Identity=28.8888888888889, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24652846, Length=311, Percent_Identity=26.0450160771704, Blast_Score=89, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ZUPT_CLOPE (Q8XMG8)

Other databases:

- EMBL:   BA000016
- RefSeq:   NP_561637.1
- GeneID:   988980
- GenomeReviews:   BA000016_GR
- KEGG:   cpe:CPE0721
- NMPDR:   fig|195102.1.peg.784
- HOGENOM:   HBG620552
- OMA:   VSVPIYY
- PhylomeDB:   Q8XMG8
- ProtClustDB:   PRK04201
- BioCyc:   CPER195102:CPE0721-MONOMER
- HAMAP:   MF_00548
- InterPro:   IPR003689

Pfam domain/function: PF02535 Zip

EC number: NA

Molecular weight: Translated: 30631; Mature: 30631

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x406642e8)-; HASH(0xd7b479c)-; HASH(0xd5796a8)-; HASH(0xd7b4820)-; HASH(0xd42000c)-; HASH(0xd7b10c4)-; HASH(0xd84491c)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGGDNMNNVLMAFLLTLLAGLATGIGSCIAFFAKKTNKKFLCVSLGFSAGVMIYVSMIE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHH
MFQTAKESLVGVMGIKAGNWITVISFFAGIAIIALIDKFVPEEENPHEVRSVEEVENEIE
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
EYKGENKEGKADIKDKTLMRTGIVTALAIAIHNFPEGLATFVSALEGASLAIPITIAIAI
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCEEEHHEEEEEE
HNIPEGISVSVPIFYATGDKKKAFLYSFLSGMSEPIGAIIGYTLLRNIFNDITLGILLSA
ECCCCCCEEEEEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAGIMVFISLDELLPTARKYGEHHLAIYGLIAGMVVMAVSLLLFI
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
>Mature Secondary Structure
MKGGDNMNNVLMAFLLTLLAGLATGIGSCIAFFAKKTNKKFLCVSLGFSAGVMIYVSMIE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHH
MFQTAKESLVGVMGIKAGNWITVISFFAGIAIIALIDKFVPEEENPHEVRSVEEVENEIE
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
EYKGENKEGKADIKDKTLMRTGIVTALAIAIHNFPEGLATFVSALEGASLAIPITIAIAI
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCEEEHHEEEEEE
HNIPEGISVSVPIFYATGDKKKAFLYSFLSGMSEPIGAIIGYTLLRNIFNDITLGILLSA
ECCCCCCEEEEEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAGIMVFISLDELLPTARKYGEHHLAIYGLIAGMVVMAVSLLLFI
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11792842