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The map label for this gene is aroQ

Identifier: 18309684

GI number: 18309684

Start: 876855

End: 877295

Strand: Direct

Name: aroQ

Synonym: CPE0702

Alternate gene names: 18309684

Gene position: 876855-877295 (Clockwise)

Preceding gene: 18309683

Following gene: 18309685

Centisome position: 28.93

GC content: 29.48

Gene sequence:

>441_bases
ATGAAAATAATGGTTATAAATGGACCTAATTTAAATCTTTTGGGGATTAGAGAAAAAGAAATCTATGGTGCTAAAGATTT
TAATCAGGTCATTGATTATATAAAAGAAGAAGGAAAAGAATTAGGGTTAGAGGTAAACTGCTTCCAGAGCAATATAGAGG
GAGAAATAATTAATTTTATTCATAATGCATACTTTGAAAAGTATGATGGAATAATCATAAATCCTGGAGCATACACACAT
TATAGCATAGCTATTTATGATGCTTTAAAAGGGGTTGAAATACCAACTGTTGAGGTACATTTAAGCAATATTCACAAAAG
AGAAGAGTTTAGACATAAATCAGTTACAGCACCAGCTTGTATTGGGCAGATAAGTGGATTTGGTGAATATGGATATATTA
TGGCAATGAATGCATTAAAAAATCATATTAAATCTAAATAA

Upstream 100 bases:

>100_bases
AAAAAGTTTGTTTTTAATAGTAGTATTCTATTAAAAATCCTAAATGGAAAGTAGGTGGATTTTAACCAAAGAAAAAATTA
ATAATTTGGTTAGAGATATT

Downstream 100 bases:

>100_bases
GATTAAAAAAATAAAATCTATTTAAATTAATAATATAAATGCTTCAGTTATAAATTTTACTAATGGTTAAAAGGGGATTT
TTATGGAGGAGAGAATTGAG

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MKIMVINGPNLNLLGIREKEIYGAKDFNQVIDYIKEEGKELGLEVNCFQSNIEGEIINFIHNAYFEKYDGIIINPGAYTH
YSIAIYDALKGVEIPTVEVHLSNIHKREEFRHKSVTAPACIGQISGFGEYGYIMAMNALKNHIKSK

Sequences:

>Translated_146_residues
MKIMVINGPNLNLLGIREKEIYGAKDFNQVIDYIKEEGKELGLEVNCFQSNIEGEIINFIHNAYFEKYDGIIINPGAYTH
YSIAIYDALKGVEIPTVEVHLSNIHKREEFRHKSVTAPACIGQISGFGEYGYIMAMNALKNHIKSK
>Mature_146_residues
MKIMVINGPNLNLLGIREKEIYGAKDFNQVIDYIKEEGKELGLEVNCFQSNIEGEIINFIHNAYFEKYDGIIINPGAYTH
YSIAIYDALKGVEIPTVEVHLSNIHKREEFRHKSVTAPACIGQISGFGEYGYIMAMNALKNHIKSK

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_CLOPE (Q8XMI6)

Other databases:

- EMBL:   BA000016
- RefSeq:   NP_561618.1
- ProteinModelPortal:   Q8XMI6
- SMR:   Q8XMI6
- GeneID:   988961
- GenomeReviews:   BA000016_GR
- KEGG:   cpe:CPE0702
- NMPDR:   fig|195102.1.peg.765
- HOGENOM:   HBG284657
- OMA:   IMVINGP
- ProtClustDB:   PRK05395
- BioCyc:   CPER195102:CPE0702-MONOMER
- BRENDA:   4.2.1.10
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 16523; Mature: 16523

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 22-22 ACT_SITE 100-100 BINDING 74-74 BINDING 80-80 BINDING 87-87 BINDING 111-111

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIMVINGPNLNLLGIREKEIYGAKDFNQVIDYIKEEGKELGLEVNCFQSNIEGEIINFI
CEEEEEECCCEEEEEECHHHCCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHH
HNAYFEKYDGIIINPGAYTHYSIAIYDALKGVEIPTVEVHLSNIHKREEFRHKSVTAPAC
HHHHHHHCCCEEECCCCCEEEEEEEEHHHCCCCCCEEEEEHHHHHHHHHHHHCCCCCHHH
IGQISGFGEYGYIMAMNALKNHIKSK
HHHHCCCCCCHHHEEHHHHHHHHCCC
>Mature Secondary Structure
MKIMVINGPNLNLLGIREKEIYGAKDFNQVIDYIKEEGKELGLEVNCFQSNIEGEIINFI
CEEEEEECCCEEEEEECHHHCCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHH
HNAYFEKYDGIIINPGAYTHYSIAIYDALKGVEIPTVEVHLSNIHKREEFRHKSVTAPAC
HHHHHHHCCCEEECCCCCEEEEEEEEHHHCCCCCCEEEEEHHHHHHHHHHHHCCCCCHHH
IGQISGFGEYGYIMAMNALKNHIKSK
HHHHCCCCCCHHHEEHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11792842