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The map label for this gene is aroA [H]

Identifier: 18309678

GI number: 18309678

Start: 871378

End: 872652

Strand: Direct

Name: aroA [H]

Synonym: CPE0696

Alternate gene names: 18309678

Gene position: 871378-872652 (Clockwise)

Preceding gene: 18309677

Following gene: 161485643

Centisome position: 28.74

GC content: 28.63

Gene sequence:

>1275_bases
GTGAAAAAGGTAATTATAACTCCTAGTAAGTTAAGGGGAAGTGTAAAAATACCACCTTCTAAAAGTATGGCTCATAGAGC
TATTATTTGTGCTTCTTTAAGCAAAGGAGAAAGTGTTATTTCTAACATAGATTTTTCAGAAGATATTATTGCAACTATGG
AAGGTATGAAATCTTTAGGAGCAAATATAAAAGTAGAAAAAGATAAACTAATTATAAATGGAGAAAATATTTTAAAGGAT
TCTAATTATAAATTTATTGATTGTAATGAATCAGGTTCCACTTTAAGATTTTTAGTTCCAATTTCCTTAATAAAAGATAA
TAGAGTTAATTTTATCGGTAGAGGAAATTTAGGGAAAAGACCATTAAAAACTTATTATGAGATTTTTGAGGAGCAAGAAA
TTAAGTATTCCTATGAGGAAGAAAATCTTGATTTGAATATAGAAGGAAGCTTAAAAGGTGGAGAATTCAAAGTTAAGGGA
AATATAAGTTCTCAATTTATAAGTGGTTTATTATTTACTCTTCCTTTATTAAAAGATGATTCTAAAATAATAATAACTAC
AGAACTTGAATCTAAAGGATATATAGATTTAACTTTAGACATGATAGAAAAGTTTGGAGTTACAATAAAAAATAATAATT
ATAGAGAATTTTTAATAAAAGGTAATCAAAGTTATAAGCCTATGAATTATAAGGTTGAAGGTGATTACTCACAGGCTGCT
TTCTATTTTTCAGCAGGGGCCTTAGGCTCAGAAATAAATTGTCTTGATTTAGATTTAAGTTCTTATCAAGGAGATAAGGA
ATGCATTGAAATATTAGAGGGTATGGGTGCTAGGCTTATAGAAAGTCAAGAAAGGTCTTTAAGTATAATTCATGGGGATT
TAAATGGAACAATTATAGATGCTTCACAATGCCCAGATATAATTCCTGTTTTGACAGTGGTTGCTGCTTTAAGTAAGGGA
GAGACTAGGATTATAAATGGAGAAAGACTTAGAATAAAAGAATGTGATAGATTAAATGCTATATGTACAGAGCTTAATAA
ACTAGGTGCAGATATAAAGGAATTAAAAGATGGACTTATAATAAATGGAGTTAAAGATTTAATAGGAGGAGAAGTATATA
GCCATAAAGATCATAGAATAGCTATGAGTTTGGCTATTGCTTCTACAAGATGCAAGAAAGAGGTTATTATAAAAGAACCA
GATTGTGTTAAAAAATCTTATCCAGGATTTTGGGAAGATTTTAAGAGCTTAGGTGGAATTTTAAGAGAAGAATAA

Upstream 100 bases:

>100_bases
TTAGAAAGGCTTTAGGGTTATATATGAAATTAATATGGGTTTAAAACAGAGGATAAAATTTATAGTGTAATTTGAAAATA
AGTATAGGGAGCGGGTAAAA

Downstream 100 bases:

>100_bases
TATATAGAATATTCAACAGAAGGGAGGAAGCTTTTAGAGATAATAAGCTTTAAAAGCAAATAAATGGGAGGAGTTTGGGG
TAATAAAATAAAATTATCTA

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MKKVIITPSKLRGSVKIPPSKSMAHRAIICASLSKGESVISNIDFSEDIIATMEGMKSLGANIKVEKDKLIINGENILKD
SNYKFIDCNESGSTLRFLVPISLIKDNRVNFIGRGNLGKRPLKTYYEIFEEQEIKYSYEEENLDLNIEGSLKGGEFKVKG
NISSQFISGLLFTLPLLKDDSKIIITTELESKGYIDLTLDMIEKFGVTIKNNNYREFLIKGNQSYKPMNYKVEGDYSQAA
FYFSAGALGSEINCLDLDLSSYQGDKECIEILEGMGARLIESQERSLSIIHGDLNGTIIDASQCPDIIPVLTVVAALSKG
ETRIINGERLRIKECDRLNAICTELNKLGADIKELKDGLIINGVKDLIGGEVYSHKDHRIAMSLAIASTRCKKEVIIKEP
DCVKKSYPGFWEDFKSLGGILREE

Sequences:

>Translated_424_residues
MKKVIITPSKLRGSVKIPPSKSMAHRAIICASLSKGESVISNIDFSEDIIATMEGMKSLGANIKVEKDKLIINGENILKD
SNYKFIDCNESGSTLRFLVPISLIKDNRVNFIGRGNLGKRPLKTYYEIFEEQEIKYSYEEENLDLNIEGSLKGGEFKVKG
NISSQFISGLLFTLPLLKDDSKIIITTELESKGYIDLTLDMIEKFGVTIKNNNYREFLIKGNQSYKPMNYKVEGDYSQAA
FYFSAGALGSEINCLDLDLSSYQGDKECIEILEGMGARLIESQERSLSIIHGDLNGTIIDASQCPDIIPVLTVVAALSKG
ETRIINGERLRIKECDRLNAICTELNKLGADIKELKDGLIINGVKDLIGGEVYSHKDHRIAMSLAIASTRCKKEVIIKEP
DCVKKSYPGFWEDFKSLGGILREE
>Mature_424_residues
MKKVIITPSKLRGSVKIPPSKSMAHRAIICASLSKGESVISNIDFSEDIIATMEGMKSLGANIKVEKDKLIINGENILKD
SNYKFIDCNESGSTLRFLVPISLIKDNRVNFIGRGNLGKRPLKTYYEIFEEQEIKYSYEEENLDLNIEGSLKGGEFKVKG
NISSQFISGLLFTLPLLKDDSKIIITTELESKGYIDLTLDMIEKFGVTIKNNNYREFLIKGNQSYKPMNYKVEGDYSQAA
FYFSAGALGSEINCLDLDLSSYQGDKECIEILEGMGARLIESQERSLSIIHGDLNGTIIDASQCPDIIPVLTVVAALSKG
ETRIINGERLRIKECDRLNAICTELNKLGADIKELKDGLIINGVKDLIGGEVYSHKDHRIAMSLAIASTRCKKEVIIKEP
DCVKKSYPGFWEDFKSLGGILREE

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=426, Percent_Identity=31.6901408450704, Blast_Score=222, Evalue=4e-59,
Organism=Saccharomyces cerevisiae, GI6320332, Length=466, Percent_Identity=27.4678111587983, Blast_Score=147, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 47211; Mature: 47211

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVIITPSKLRGSVKIPPSKSMAHRAIICASLSKGESVISNIDFSEDIIATMEGMKSLG
CCEEEECHHHCCCCEECCCCHHHHHHEEEEEECCCCHHHHHCCCCCHHHHHHHHHHHHHC
ANIKVEKDKLIINGENILKDSNYKFIDCNESGSTLRFLVPISLIKDNRVNFIGRGNLGKR
CCEEEECCEEEECCCHHEECCCEEEEEECCCCCEEEEEEEEEEECCCCEEEEECCCCCCC
PLKTYYEIFEEQEIKYSYEEENLDLNIEGSLKGGEFKVKGNISSQFISGLLFTLPLLKDD
HHHHHHHHHCCCCCEEEECCCCEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHCCCC
SKIIITTELESKGYIDLTLDMIEKFGVTIKNNNYREFLIKGNQSYKPMNYKVEGDYSQAA
CEEEEEEEECCCCEEEEEHHHHHHCCCEEECCCEEEEEEECCCCCCCCEEEECCCCCCEE
FYFSAGALGSEINCLDLDLSSYQGDKECIEILEGMGARLIESQERSLSIIHGDLNGTIID
EEEECCCCCCCCEEEEEEHHHCCCCHHHHHHHHCCCHHHHHCCCCEEEEEEECCCCEEEE
ASQCPDIIPVLTVVAALSKGETRIINGERLRIKECDRLNAICTELNKLGADIKELKDGLI
HHCCCCHHHHHHHHHHHCCCCEEEECCCEEEEHHHHHHHHHHHHHHHHCCCHHHHHCCEE
INGVKDLIGGEVYSHKDHRIAMSLAIASTRCKKEVIIKEPDCVKKSYPGFWEDFKSLGGI
EECHHHHHCCCEECCCCCEEEEEEEHHHHCCCCCEEECCCCHHHCCCCCHHHHHHHHHHH
LREE
HCCC
>Mature Secondary Structure
MKKVIITPSKLRGSVKIPPSKSMAHRAIICASLSKGESVISNIDFSEDIIATMEGMKSLG
CCEEEECHHHCCCCEECCCCHHHHHHEEEEEECCCCHHHHHCCCCCHHHHHHHHHHHHHC
ANIKVEKDKLIINGENILKDSNYKFIDCNESGSTLRFLVPISLIKDNRVNFIGRGNLGKR
CCEEEECCEEEECCCHHEECCCEEEEEECCCCCEEEEEEEEEEECCCCEEEEECCCCCCC
PLKTYYEIFEEQEIKYSYEEENLDLNIEGSLKGGEFKVKGNISSQFISGLLFTLPLLKDD
HHHHHHHHHCCCCCEEEECCCCEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHCCCC
SKIIITTELESKGYIDLTLDMIEKFGVTIKNNNYREFLIKGNQSYKPMNYKVEGDYSQAA
CEEEEEEEECCCCEEEEEHHHHHHCCCEEECCCEEEEEEECCCCCCCCEEEECCCCCCEE
FYFSAGALGSEINCLDLDLSSYQGDKECIEILEGMGARLIESQERSLSIIHGDLNGTIID
EEEECCCCCCCCEEEEEEHHHCCCCHHHHHHHHCCCHHHHHCCCCEEEEEEECCCCEEEE
ASQCPDIIPVLTVVAALSKGETRIINGERLRIKECDRLNAICTELNKLGADIKELKDGLI
HHCCCCHHHHHHHHHHHCCCCEEEECCCEEEEHHHHHHHHHHHHHHHHCCCHHHHHCCEE
INGVKDLIGGEVYSHKDHRIAMSLAIASTRCKKEVIIKEPDCVKKSYPGFWEDFKSLGGI
EECHHHHHCCCEECCCCCEEEEEEEHHHHCCCCCEEECCCCHHHCCCCCHHHHHHHHHHH
LREE
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA