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The map label for this gene is aroB [H]

Identifier: 18309677

GI number: 18309677

Start: 870079

End: 871131

Strand: Direct

Name: aroB [H]

Synonym: CPE0695

Alternate gene names: 18309677

Gene position: 870079-871131 (Clockwise)

Preceding gene: 18309676

Following gene: 18309678

Centisome position: 28.7

GC content: 28.58

Gene sequence:

>1053_bases
ATGAAAGTTTTAAGAGTAAATTTAGATGAAAAAAGTTATGATATAGTAATTCAAAAGGATTTAAAAGATTATTTTGGAGA
ATACATAAAAACTGTATTTGATGGGAAAAAAGTAGCTATTATAACTGATGATAATTTAAATGATATATATGGAGAGGCTA
TAAAGAAAAACATAGAAAATGAAGGTTTTGAAGTTGAAGTTATTTCTGTTACACCAGGAGAAAAGAGTAAATCTTTTAGC
GTATTACCAGGAATATATAATAAACTTTTAGATTTTAAACTAACTAGAAGCGATTTAATCATAGCTCTAGGTGGAGGTGT
TGTTGGAGACCTTGCAGGTTTTGTTGCCTCAACTTTTTTAAGAGGAATTAGCTTTATACAAATACCTACATCATTATTAG
CTCAAGTTGATTCTAGTGTTGGTGGTAAGGTAGCTGTTGACTTAGAAAGAGGGAAGAATTTAGTAGGAAGCTTTTATCAT
CCTGAATTAGTATTAATAGATCCAAATATGCTTGGAACACTTCCAGAAAAATATTTTAATGATGGCCTTGGAGAGGTAAT
AAAATATGGATGCATTAAGAGTAAAGAGTTATTTGAAAAGTTAGAGGGCTTTGAAAATAAAGAGGATCTAAAAGAGAATA
TTGGAGAAATTATTTATGAATGTTGCAATATAAAAAGAGAAGTGGTTGAAAATGATGAAAAAGATTTAGGAGAAAGAATG
GTTCTAAACTTTGGTCATACTTTAGGTCATGCCATAGAGCAAATTTATAATTATGAAATTTATTCTCATGGGGAAGCTGT
TGCCATAGGAATGAATATGATAAGCAAGATTGCAGAAGAAAAGGATCTTACTAAAAAAGGAACAGCAGAAAGAATTGAGA
GTTTATTAAAGAAGTATGGATTAAATACTGATGTTAACATTGAAGATAATGGATTAGCTAGAGAAGCTATAAAATTAGAT
AAGAAGAATTTAAATGGAAATTTAAATGTTATTCTTTTAAAAGATATTGGGGAAGGGTATATATATAATACAACTGTAGA
ATTTTTTGAATAA

Upstream 100 bases:

>100_bases
ATAGAATATTATTTAATTTAGTGGGAGTGTTTAAACTCCCATTAAATTTATACTTAAATAGAAATAACATAATAAAATTA
AAGGGTTTGGAGTGATAAAA

Downstream 100 bases:

>100_bases
AGACATAGGGGTTAAGTTAATATTAATTTAAAGTTATTACTTTATAAATAACTTAACAACTTGGTTTCTTAAAGGAATTT
AGAGAAAATTTAATTATTTC

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MKVLRVNLDEKSYDIVIQKDLKDYFGEYIKTVFDGKKVAIITDDNLNDIYGEAIKKNIENEGFEVEVISVTPGEKSKSFS
VLPGIYNKLLDFKLTRSDLIIALGGGVVGDLAGFVASTFLRGISFIQIPTSLLAQVDSSVGGKVAVDLERGKNLVGSFYH
PELVLIDPNMLGTLPEKYFNDGLGEVIKYGCIKSKELFEKLEGFENKEDLKENIGEIIYECCNIKREVVENDEKDLGERM
VLNFGHTLGHAIEQIYNYEIYSHGEAVAIGMNMISKIAEEKDLTKKGTAERIESLLKKYGLNTDVNIEDNGLAREAIKLD
KKNLNGNLNVILLKDIGEGYIYNTTVEFFE

Sequences:

>Translated_350_residues
MKVLRVNLDEKSYDIVIQKDLKDYFGEYIKTVFDGKKVAIITDDNLNDIYGEAIKKNIENEGFEVEVISVTPGEKSKSFS
VLPGIYNKLLDFKLTRSDLIIALGGGVVGDLAGFVASTFLRGISFIQIPTSLLAQVDSSVGGKVAVDLERGKNLVGSFYH
PELVLIDPNMLGTLPEKYFNDGLGEVIKYGCIKSKELFEKLEGFENKEDLKENIGEIIYECCNIKREVVENDEKDLGERM
VLNFGHTLGHAIEQIYNYEIYSHGEAVAIGMNMISKIAEEKDLTKKGTAERIESLLKKYGLNTDVNIEDNGLAREAIKLD
KKNLNGNLNVILLKDIGEGYIYNTTVEFFE
>Mature_350_residues
MKVLRVNLDEKSYDIVIQKDLKDYFGEYIKTVFDGKKVAIITDDNLNDIYGEAIKKNIENEGFEVEVISVTPGEKSKSFS
VLPGIYNKLLDFKLTRSDLIIALGGGVVGDLAGFVASTFLRGISFIQIPTSLLAQVDSSVGGKVAVDLERGKNLVGSFYH
PELVLIDPNMLGTLPEKYFNDGLGEVIKYGCIKSKELFEKLEGFENKEDLKENIGEIIYECCNIKREVVENDEKDLGERM
VLNFGHTLGHAIEQIYNYEIYSHGEAVAIGMNMISKIAEEKDLTKKGTAERIESLLKKYGLNTDVNIEDNGLAREAIKLD
KKNLNGNLNVILLKDIGEGYIYNTTVEFFE

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=343, Percent_Identity=40.2332361516035, Blast_Score=223, Evalue=1e-59,
Organism=Saccharomyces cerevisiae, GI6320332, Length=365, Percent_Identity=33.6986301369863, Blast_Score=181, Evalue=1e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 39121; Mature: 39121

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLRVNLDEKSYDIVIQKDLKDYFGEYIKTVFDGKKVAIITDDNLNDIYGEAIKKNIEN
CEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCC
EGFEVEVISVTPGEKSKSFSVLPGIYNKLLDFKLTRSDLIIALGGGVVGDLAGFVASTFL
CCEEEEEEEECCCCCCCCCEECHHHHHHHHCCEECCCCEEEEECCCHHHHHHHHHHHHHH
RGISFIQIPTSLLAQVDSSVGGKVAVDLERGKNLVGSFYHPELVLIDPNMLGTLPEKYFN
HCCHHHHHHHHHHHHHHHCCCCEEEEEHHHCCCHHCCCCCCEEEEECCCHHHCCCHHHHC
DGLGEVIKYGCIKSKELFEKLEGFENKEDLKENIGEIIYECCNIKREVVENDEKDLGERM
CCHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHH
VLNFGHTLGHAIEQIYNYEIYSHGEAVAIGMNMISKIAEEKDLTKKGTAERIESLLKKYG
HHHHHHHHHHHHHHHHCCCEECCCCEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHC
LNTDVNIEDNGLAREAIKLDKKNLNGNLNVILLKDIGEGYIYNTTVEFFE
CCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCEEEECEEEECC
>Mature Secondary Structure
MKVLRVNLDEKSYDIVIQKDLKDYFGEYIKTVFDGKKVAIITDDNLNDIYGEAIKKNIEN
CEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCC
EGFEVEVISVTPGEKSKSFSVLPGIYNKLLDFKLTRSDLIIALGGGVVGDLAGFVASTFL
CCEEEEEEEECCCCCCCCCEECHHHHHHHHCCEECCCCEEEEECCCHHHHHHHHHHHHHH
RGISFIQIPTSLLAQVDSSVGGKVAVDLERGKNLVGSFYHPELVLIDPNMLGTLPEKYFN
HCCHHHHHHHHHHHHHHHCCCCEEEEEHHHCCCHHCCCCCCEEEEECCCHHHCCCHHHHC
DGLGEVIKYGCIKSKELFEKLEGFENKEDLKENIGEIIYECCNIKREVVENDEKDLGERM
CCHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHH
VLNFGHTLGHAIEQIYNYEIYSHGEAVAIGMNMISKIAEEKDLTKKGTAERIESLLKKYG
HHHHHHHHHHHHHHHHCCCEECCCCEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHC
LNTDVNIEDNGLAREAIKLDKKNLNGNLNVILLKDIGEGYIYNTTVEFFE
CCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCEEEECEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA