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The map label for this gene is licC [H]

Identifier: 18309611

GI number: 18309611

Start: 789373

End: 790056

Strand: Direct

Name: licC [H]

Synonym: CPE0629

Alternate gene names: 18309611

Gene position: 789373-790056 (Clockwise)

Preceding gene: 18309610

Following gene: 18309615

Centisome position: 26.04

GC content: 27.78

Gene sequence:

>684_bases
ATGAGAGCAATATTACTAGCAGCAGGAATGGGAACTAGATTAAGACCCCTAACTTTAGATACACCTAAGTCACTTATAGA
AGTTAATGGAAGACCTCTTTTAGAAAGACAGATAGAATTTTTAAGAGAAAGAGGAGTAGAAGAAATAATTGTAGTTACAG
GTTATCTTGCAGAGAAATTTGATTATTTAAAGGATAAATACGGAGTAAAACTAGTTAATAATGATAAATATGATATATAT
AACAATATATATACTATGTATTTAGTTAGAGAATATTTAGAGAATACCTATGTTGTTGATGCTGATGTTTATATATCAGA
AAATTTCTTATTAGAAAAACCAGAAACATCAATGTATTTTTCTGCCAATAAACAAGGTTTTAAAGGAGAATGGAAACTTA
GCTTTGATGAGGATTTAAAGGTAAATGATATAGAAGTTGGAGATGATGAGGGCTATATATTATGTGGAGTATCTTATTGG
GATAAGAAAGATACAGATATAATAGTTAAGGAGCTTGAAGACATGGTTGAAAATGGCGATTTTAGTGAGTTATATTGGGA
TGATATTGTAAAGAATAATATTTCTAAGTTAGATATTCGCATTGAAAAGATTTCAGAAAATAGTATTTATGAAATTGATA
ATTTAGAAGAATTAGACTATGTTAAATCAGTAGTAGAGAAATAA

Upstream 100 bases:

>100_bases
TACTAATTAAGATGGGATTGTAAATGCCTTAATATTAGATTATTTTAAAGAAAAAGAAATATAAAGTAAGTTTTGAGAGA
ATAATAAAGGAGATTAATAA

Downstream 100 bases:

>100_bases
TAAAGACAAGCTATTAGCTTAAGTTTTAGCTAATAGCTTGTCTCTTTTTTATATAAATTAAAATAGACTTTAATAATTAC
TAATAATTTTATAAATTAAA

Product: lic-1 operon protein

Products: dTDPglucose; Diphosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MRAILLAAGMGTRLRPLTLDTPKSLIEVNGRPLLERQIEFLRERGVEEIIVVTGYLAEKFDYLKDKYGVKLVNNDKYDIY
NNIYTMYLVREYLENTYVVDADVYISENFLLEKPETSMYFSANKQGFKGEWKLSFDEDLKVNDIEVGDDEGYILCGVSYW
DKKDTDIIVKELEDMVENGDFSELYWDDIVKNNISKLDIRIEKISENSIYEIDNLEELDYVKSVVEK

Sequences:

>Translated_227_residues
MRAILLAAGMGTRLRPLTLDTPKSLIEVNGRPLLERQIEFLRERGVEEIIVVTGYLAEKFDYLKDKYGVKLVNNDKYDIY
NNIYTMYLVREYLENTYVVDADVYISENFLLEKPETSMYFSANKQGFKGEWKLSFDEDLKVNDIEVGDDEGYILCGVSYW
DKKDTDIIVKELEDMVENGDFSELYWDDIVKNNISKLDIRIEKISENSIYEIDNLEELDYVKSVVEK
>Mature_227_residues
MRAILLAAGMGTRLRPLTLDTPKSLIEVNGRPLLERQIEFLRERGVEEIIVVTGYLAEKFDYLKDKYGVKLVNNDKYDIY
NNIYTMYLVREYLENTYVVDADVYISENFLLEKPETSMYFSANKQGFKGEWKLSFDEDLKVNDIEVGDDEGYILCGVSYW
DKKDTDIIVKELEDMVENGDFSELYWDDIVKNNISKLDIRIEKISENSIYEIDNLEELDYVKSVVEK

Specific function: Catalyzes The Formation Of Dtdp-Glucose, From Dttp And Glucose 1-Phosphate, As Well As Its Pyrophosphorolysis. [C]

COG id: COG4750

COG function: function code M; CTP:phosphocholine cytidylyltransferase involved in choline phosphorylation for cell surface LPS epitopes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Caenorhabditis elegans, GI133931050, Length=110, Percent_Identity=35.4545454545455, Blast_Score=74, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017189
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: 2.7.7.24 [C]

Molecular weight: Translated: 26576; Mature: 26576

Theoretical pI: Translated: 4.16; Mature: 4.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAILLAAGMGTRLRPLTLDTPKSLIEVNGRPLLERQIEFLRERGVEEIIVVTGYLAEKF
CCEEEEECCCCCCEEEEECCCCHHHHEECCCCHHHHHHHHHHHCCCCEEEEEEHHHHHHH
DYLKDKYGVKLVNNDKYDIYNNIYTMYLVREYLENTYVVDADVYISENFLLEKPETSMYF
HHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEEECCEEEECCCCCEEE
SANKQGFKGEWKLSFDEDLKVNDIEVGDDEGYILCGVSYWDKKDTDIIVKELEDMVENGD
ECCCCCCCCEEEECCCCCCCEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCC
FSELYWDDIVKNNISKLDIRIEKISENSIYEIDNLEELDYVKSVVEK
CCHHHHHHHHHCCCCEEEEEEEEECCCCEEECCCCHHHHHHHHHHCC
>Mature Secondary Structure
MRAILLAAGMGTRLRPLTLDTPKSLIEVNGRPLLERQIEFLRERGVEEIIVVTGYLAEKF
CCEEEEECCCCCCEEEEECCCCHHHHEECCCCHHHHHHHHHHHCCCCEEEEEEHHHHHHH
DYLKDKYGVKLVNNDKYDIYNNIYTMYLVREYLENTYVVDADVYISENFLLEKPETSMYF
HHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEEECCEEEECCCCCEEE
SANKQGFKGEWKLSFDEDLKVNDIEVGDDEGYILCGVSYWDKKDTDIIVKELEDMVENGD
ECCCCCCCCEEEECCCCCCCEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCC
FSELYWDDIVKNNISKLDIRIEKISENSIYEIDNLEELDYVKSVVEK
CCHHHHHHHHHCCCCEEEEEEEEECCCCEEECCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dTTP; D-Glucose 1-phosphate; H+ [C]

Specific reaction: dTTP + D-Glucose 1-phosphate + H+ --> dTDPglucose + Diphosphate [C]

General reaction: Nucleotidyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2479481; 7542800 [H]