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The map label for this gene is qseB [H]

Identifier: 17548121

GI number: 17548121

Start: 3681029

End: 3681694

Strand: Reverse

Name: qseB [H]

Synonym: RSc3404

Alternate gene names: 17548121

Gene position: 3681694-3681029 (Counterclockwise)

Preceding gene: 17548122

Following gene: 17548120

Centisome position: 99.07

GC content: 72.52

Gene sequence:

>666_bases
ATGCGAGTCCTGCTGATCGAAGACGATCCGATGATCGGCGCGGTGGTGGAGGCCGCGCTGCGCGATGCCGCCTATGCGGT
GGACTGGGTGCGCGACGGCCGGACCGCCGTCGACGTGAGCGCGCACCAGCACTACGACCTGCTGCTGCTCGACCTCGGCC
TGCCGGGCCAGGACGGCCACGCGGTGCTGCGCACGCTGCGCGCGCGGGACAACCCGGTGCCGGTGCTGATCCTCACCGCG
CGCGATGCGGTGGACGAGCGCGTGCGCGGCCTGGACGGCGGCGCCGACGACTACGTGCTCAAACCCTTCGAGATGGTGGA
ACTGCTGGCGCGCATGCGCGCCGTGCTGCGCCGCCGGGGCGGGGCCGCCAGCCCGGTGCTGAGCAACGGCGTGCTGTCGC
TCGACCCGGCCACGCACGAGGTGCGCGCGGGCGACGGCGAGCCGGTGCGCCTGTCGGGCCGCGAGTTCGCGCTGCTGCAA
GCGCTGATGCTGCGGCCCGGCGCCATCCTGTCGCGCGGCGAGCTGGAGGAGCGCATCTACGGCTGGGGCCACGAGGTGGC
CAGCAACGCGGTCGAGTTCCTCATCCACGCGCTGCGCAAGAAGCTGGGCGCGGAATCGATCAAGAACGTCAGGGGCGTGG
GATGGATGGTGTCCAAGGGCCGGTGA

Upstream 100 bases:

>100_bases
CTTGCTGGCCACCGTCGGCCATGCGAGCTGGCAGGCGCGGCGCGTGAGCCTGCGGTCGGCGTAGGCCGCCTTTTTCGACA
GAACCCGGAGCCGAAACCGG

Downstream 100 bases:

>100_bases
AGCCATCGCTGCAGCGGCGGCTGTCGCTGTGGCTGTCGGCGATCATCGTGGCGGTGGCGGTGGCGGCGGGGGGCTTCGCC
TTCGTGTCGGCGTTCAGCGA

Product: response regulator transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MRVLLIEDDPMIGAVVEAALRDAAYAVDWVRDGRTAVDVSAHQHYDLLLLDLGLPGQDGHAVLRTLRARDNPVPVLILTA
RDAVDERVRGLDGGADDYVLKPFEMVELLARMRAVLRRRGGAASPVLSNGVLSLDPATHEVRAGDGEPVRLSGREFALLQ
ALMLRPGAILSRGELEERIYGWGHEVASNAVEFLIHALRKKLGAESIKNVRGVGWMVSKGR

Sequences:

>Translated_221_residues
MRVLLIEDDPMIGAVVEAALRDAAYAVDWVRDGRTAVDVSAHQHYDLLLLDLGLPGQDGHAVLRTLRARDNPVPVLILTA
RDAVDERVRGLDGGADDYVLKPFEMVELLARMRAVLRRRGGAASPVLSNGVLSLDPATHEVRAGDGEPVRLSGREFALLQ
ALMLRPGAILSRGELEERIYGWGHEVASNAVEFLIHALRKKLGAESIKNVRGVGWMVSKGR
>Mature_221_residues
MRVLLIEDDPMIGAVVEAALRDAAYAVDWVRDGRTAVDVSAHQHYDLLLLDLGLPGQDGHAVLRTLRARDNPVPVLILTA
RDAVDERVRGLDGGADDYVLKPFEMVELLARMRAVLRRRGGAASPVLSNGVLSLDPATHEVRAGDGEPVRLSGREFALLQ
ALMLRPGAILSRGELEERIYGWGHEVASNAVEFLIHALRKKLGAESIKNVRGVGWMVSKGR

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. Currently it is not known whether this effect is direct or not [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=219, Percent_Identity=46.5753424657534, Blast_Score=193, Evalue=7e-51,
Organism=Escherichia coli, GI1790552, Length=217, Percent_Identity=41.9354838709677, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI87082012, Length=219, Percent_Identity=40.1826484018265, Blast_Score=146, Evalue=9e-37,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=35.2941176470588, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=33.4821428571429, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=37.1681415929204, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=34.2105263157895, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1790860, Length=220, Percent_Identity=34.5454545454545, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=32.15859030837, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI1787229, Length=224, Percent_Identity=31.6964285714286, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=33.6244541484716, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI1786911, Length=202, Percent_Identity=33.6633663366337, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=28.1938325991189, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=30.0429184549356, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=32.7102803738318, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=34.2105263157895, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1790299, Length=108, Percent_Identity=35.1851851851852, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788713, Length=105, Percent_Identity=32.3809523809524, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24120; Mature: 24120

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLLIEDDPMIGAVVEAALRDAAYAVDWVRDGRTAVDVSAHQHYDLLLLDLGLPGQDGH
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEECCCCCCHH
AVLRTLRARDNPVPVLILTARDAVDERVRGLDGGADDYVLKPFEMVELLARMRAVLRRRG
HHHHHHHHCCCCCCEEEEECCHHHHHHHHCCCCCCCCCEECHHHHHHHHHHHHHHHHHCC
GAASPVLSNGVLSLDPATHEVRAGDGEPVRLSGREFALLQALMLRPGAILSRGELEERIY
CCCCCHHHCCEEEECCCCCEEECCCCCEEEECCCHHHHHHHHHHCCCCHHCHHHHHHHHH
GWGHEVASNAVEFLIHALRKKLGAESIKNVRGVGWMVSKGR
CCCHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCEEEECCC
>Mature Secondary Structure
MRVLLIEDDPMIGAVVEAALRDAAYAVDWVRDGRTAVDVSAHQHYDLLLLDLGLPGQDGH
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEECCCCCCHH
AVLRTLRARDNPVPVLILTARDAVDERVRGLDGGADDYVLKPFEMVELLARMRAVLRRRG
HHHHHHHHCCCCCCEEEEECCHHHHHHHHCCCCCCCCCEECHHHHHHHHHHHHHHHHHCC
GAASPVLSNGVLSLDPATHEVRAGDGEPVRLSGREFALLQALMLRPGAILSRGELEERIY
CCCCCHHHCCEEEECCCCCEEECCCCCEEEECCCHHHHHHHHHHCCCCHHCHHHHHHHHH
GWGHEVASNAVEFLIHALRKKLGAESIKNVRGVGWMVSKGR
CCCHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]