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The map label for this gene is qseC [H]

Identifier: 17548120

GI number: 17548120

Start: 3679713

End: 3681053

Strand: Reverse

Name: qseC [H]

Synonym: RSc3403

Alternate gene names: 17548120

Gene position: 3681053-3679713 (Counterclockwise)

Preceding gene: 17548121

Following gene: 17548119

Centisome position: 99.05

GC content: 73.01

Gene sequence:

>1341_bases
ATGGATGGTGTCCAAGGGCCGGTGAAGCCATCGCTGCAGCGGCGGCTGTCGCTGTGGCTGTCGGCGATCATCGTGGCGGT
GGCGGTGGCGGCGGGGGGCTTCGCCTTCGTGTCGGCGTTCAGCGAGGCGCACGAGCTGCAGGACGACGTGCTGCGCCAGG
TCGGAGCGATGTTCGATCCGCAGCATCTGCCCGCCGCGTCCGCCGAGGCGCCGATGGCCGATCAGGAATCGCGCGTCGTC
GTGCAGTTGCTGCCGGCACCGGGGGCGGACGCGGGCCGCGCCTCGACCCGCGCCACGCCGGTGTTCCCGTCCACCCTGGC
CGACGGCATGCAGACCGCGCGCGCCGGCAAATACAACTACCGCGTATGGGTGCGCACGCTCGCCGACGGCCAGCGCATCG
CCGTGGCGCAGGAGACCGCCGTGCGCAACGAAACCGCGCGCAACAGTGCGCTGCACACGGTGATGCCGTTCCTGATCCTG
GTGCCGATCCTGCTGCTGGCCATGGCGGATGTGCTGCGCAAGATGTTCGCGCCGATCCGCCGGCTCGCGCACGAGGTCGA
CCAGCGCGATGAGCGCCAGCTGCACGCCATCGCGCCCGATGCGGTGCCCGCGGAGGTGCGCCCCTTCGTGGTGGCCATCA
ACCGGCTGCTGGCGCGCGTGGCGCAGTCGGTGCAGGCGCAGCACCGCTTCGTCGCCGATGCGGCGCACGAGCTGCGCACG
CCGCTCACGGCGCTGTCGCTGCAGGCCGAGCGGCTGGGGGAGGCGCCCATGTCGGCGGCCGCGCAGGAGCGGCTGGCCGC
GCTGCGGCAGGGCATCGAGCGCAGCCGCGCGCTGCTGGAGCAGTTGCTGACGCTGGCGCGCGCCCAGGCGGACACGCAGG
CGCCGGCGGGCGCGGTCTCTGTGCAGCGGGTGTTCCGCAGCGTGCTGGAAGACCTGATGCCGCTGGCCGAGGCCAAGCGG
CTGGACCTGGGCGTCACCACAGACGCCGACGCACGCGTGCGCGCCGGCGAGCTCGACCTGTTCGTCATCCTGCGCAACCT
GGTCGACAACGCGATCCGCTACACGCCGGACGGCGGCAGCATCGACCTGTCGCTGCAGACCGACGGCGACCTGGCGCACA
TCACCGTGCAGGACACCGGGCCGGGCATCCCCGCATCGGAACGCGCGCGCGTGTTCGATGCGTTCTACCGCGTACTCGGC
AACGGCGCCACCGGCTCGGGGCTGGGGCTGTCGATCGTCGGCACGCTGGTGCAGCGGCTGGGCGGCGAGGTCGCGCTGGA
CGAGGCGGCCGGCACGGCGAGCGGGCTGCGGGCGACGGTGCGGCTACCGTTGGCCGAATAG

Upstream 100 bases:

>100_bases
GCTGGGGCCACGAGGTGGCCAGCAACGCGGTCGAGTTCCTCATCCACGCGCTGCGCAAGAAGCTGGGCGCGGAATCGATC
AAGAACGTCAGGGGCGTGGG

Downstream 100 bases:

>100_bases
CACACCCCACTTCGGCAGCCGTCATGTGAACGCGGCGCCATGCGATGATCGGCGGTTGCCCCGGCGTTGTGCCGGCCGTT
CTTCCGCCCATCGACCACGA

Product: two-component sensor kinase transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MDGVQGPVKPSLQRRLSLWLSAIIVAVAVAAGGFAFVSAFSEAHELQDDVLRQVGAMFDPQHLPAASAEAPMADQESRVV
VQLLPAPGADAGRASTRATPVFPSTLADGMQTARAGKYNYRVWVRTLADGQRIAVAQETAVRNETARNSALHTVMPFLIL
VPILLLAMADVLRKMFAPIRRLAHEVDQRDERQLHAIAPDAVPAEVRPFVVAINRLLARVAQSVQAQHRFVADAAHELRT
PLTALSLQAERLGEAPMSAAAQERLAALRQGIERSRALLEQLLTLARAQADTQAPAGAVSVQRVFRSVLEDLMPLAEAKR
LDLGVTTDADARVRAGELDLFVILRNLVDNAIRYTPDGGSIDLSLQTDGDLAHITVQDTGPGIPASERARVFDAFYRVLG
NGATGSGLGLSIVGTLVQRLGGEVALDEAAGTASGLRATVRLPLAE

Sequences:

>Translated_446_residues
MDGVQGPVKPSLQRRLSLWLSAIIVAVAVAAGGFAFVSAFSEAHELQDDVLRQVGAMFDPQHLPAASAEAPMADQESRVV
VQLLPAPGADAGRASTRATPVFPSTLADGMQTARAGKYNYRVWVRTLADGQRIAVAQETAVRNETARNSALHTVMPFLIL
VPILLLAMADVLRKMFAPIRRLAHEVDQRDERQLHAIAPDAVPAEVRPFVVAINRLLARVAQSVQAQHRFVADAAHELRT
PLTALSLQAERLGEAPMSAAAQERLAALRQGIERSRALLEQLLTLARAQADTQAPAGAVSVQRVFRSVLEDLMPLAEAKR
LDLGVTTDADARVRAGELDLFVILRNLVDNAIRYTPDGGSIDLSLQTDGDLAHITVQDTGPGIPASERARVFDAFYRVLG
NGATGSGLGLSIVGTLVQRLGGEVALDEAAGTASGLRATVRLPLAE
>Mature_446_residues
MDGVQGPVKPSLQRRLSLWLSAIIVAVAVAAGGFAFVSAFSEAHELQDDVLRQVGAMFDPQHLPAASAEAPMADQESRVV
VQLLPAPGADAGRASTRATPVFPSTLADGMQTARAGKYNYRVWVRTLADGQRIAVAQETAVRNETARNSALHTVMPFLIL
VPILLLAMADVLRKMFAPIRRLAHEVDQRDERQLHAIAPDAVPAEVRPFVVAINRLLARVAQSVQAQHRFVADAAHELRT
PLTALSLQAERLGEAPMSAAAQERLAALRQGIERSRALLEQLLTLARAQADTQAPAGAVSVQRVFRSVLEDLMPLAEAKR
LDLGVTTDADARVRAGELDLFVILRNLVDNAIRYTPDGGSIDLSLQTDGDLAHITVQDTGPGIPASERARVFDAFYRVLG
NGATGSGLGLSIVGTLVQRLGGEVALDEAAGTASGLRATVRLPLAE

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=327, Percent_Identity=34.8623853211009, Blast_Score=165, Evalue=5e-42,
Organism=Escherichia coli, GI1790551, Length=293, Percent_Identity=33.4470989761092, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI1786783, Length=296, Percent_Identity=30.7432432432432, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI145693157, Length=230, Percent_Identity=30.4347826086957, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1786600, Length=239, Percent_Identity=31.3807531380753, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI87082128, Length=308, Percent_Identity=28.2467532467532, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI1790861, Length=322, Percent_Identity=30.4347826086957, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788279, Length=291, Percent_Identity=26.4604810996564, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1790346, Length=274, Percent_Identity=29.5620437956204, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI48994928, Length=235, Percent_Identity=26.8085106382979, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1787894, Length=248, Percent_Identity=30.241935483871, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081816, Length=284, Percent_Identity=28.8732394366197, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788393, Length=286, Percent_Identity=25.8741258741259, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789149, Length=249, Percent_Identity=25.7028112449799, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787374, Length=273, Percent_Identity=26.007326007326, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1789808, Length=253, Percent_Identity=28.4584980237154, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1786912, Length=223, Percent_Identity=29.1479820627803, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1788713, Length=254, Percent_Identity=22.8346456692913, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1790436, Length=215, Percent_Identity=26.9767441860465, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 47602; Mature: 47602

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGVQGPVKPSLQRRLSLWLSAIIVAVAVAAGGFAFVSAFSEAHELQDDVLRQVGAMFDP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QHLPAASAEAPMADQESRVVVQLLPAPGADAGRASTRATPVFPSTLADGMQTARAGKYNY
CCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEE
RVWVRTLADGQRIAVAQETAVRNETARNSALHTVMPFLILVPILLLAMADVLRKMFAPIR
EEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLAHEVDQRDERQLHAIAPDAVPAEVRPFVVAINRLLARVAQSVQAQHRFVADAAHELRT
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PLTALSLQAERLGEAPMSAAAQERLAALRQGIERSRALLEQLLTLARAQADTQAPAGAVS
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
VQRVFRSVLEDLMPLAEAKRLDLGVTTDADARVRAGELDLFVILRNLVDNAIRYTPDGGS
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHEECCCCCE
IDLSLQTDGDLAHITVQDTGPGIPASERARVFDAFYRVLGNGATGSGLGLSIVGTLVQRL
EEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
GGEVALDEAAGTASGLRATVRLPLAE
CCCEEEHHHCCCHHCCEEEEECCCCC
>Mature Secondary Structure
MDGVQGPVKPSLQRRLSLWLSAIIVAVAVAAGGFAFVSAFSEAHELQDDVLRQVGAMFDP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QHLPAASAEAPMADQESRVVVQLLPAPGADAGRASTRATPVFPSTLADGMQTARAGKYNY
CCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEE
RVWVRTLADGQRIAVAQETAVRNETARNSALHTVMPFLILVPILLLAMADVLRKMFAPIR
EEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLAHEVDQRDERQLHAIAPDAVPAEVRPFVVAINRLLARVAQSVQAQHRFVADAAHELRT
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PLTALSLQAERLGEAPMSAAAQERLAALRQGIERSRALLEQLLTLARAQADTQAPAGAVS
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
VQRVFRSVLEDLMPLAEAKRLDLGVTTDADARVRAGELDLFVILRNLVDNAIRYTPDGGS
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHEECCCCCE
IDLSLQTDGDLAHITVQDTGPGIPASERARVFDAFYRVLGNGATGSGLGLSIVGTLVQRL
EEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
GGEVALDEAAGTASGLRATVRLPLAE
CCCEEEHHHCCCHHCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]