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The map label for this gene is cpdB [H]

Identifier: 17548080

GI number: 17548080

Start: 3621887

End: 3623932

Strand: Reverse

Name: cpdB [H]

Synonym: RSc3363

Alternate gene names: 17548080

Gene position: 3623932-3621887 (Counterclockwise)

Preceding gene: 17548086

Following gene: 17548079

Centisome position: 97.51

GC content: 67.64

Gene sequence:

>2046_bases
ATGCAAGTCCGACCGTTGTCGTCGGCGGCATTGCCGCTGGCCGCCTGGTTGTCGCTGTCGCTGACCGCCTGCGGCGGCAG
CGACGATCCGAGCGCCGCCTCCGCCGCGCCCACCGGCACCAAGGCAACGCTCGCCGTGCTGGAGACCACCGACCTGCACA
CCAACGTGCTGTCGTACGACTACTTCAAGCTGGCCGCCGACAGCTCGCTCGGCTTCGAGCGCGTGTCGACGCTGATCGCG
CAGGCGCGCGCGCAGTTTCCCAACACGCTGCTGCTCGACAACGGCGACACCATCCAGGGCACCGCGCTGTCCGACTACCA
GGCCCTGGTGAACCCCATCGCCTGCGGCCAGGCCCTGGCCATCTACAAGGTGATGAACGCAGCCGGGTACGACGGCGGCA
GCATCGGCAACCACGAGTTCAACTACGGCCTGCCGTACCTGTCGCAGGTCACCGGCAACACCTTCAACGTGGCCGGCATG
GCCGATCCTGCGCAGCAGACCCGGTGCGCGGGGCCGAGCTTTCCGCAGGTGCTGGCCAACGTGATGAGCGCCAAGACCAG
CGCGCCGCTGTTCCAGCCCTACACCCTCCTGACCAAGACCGTGACGGCGACCGCGCCGGACGGCAGCACCGTCAGCGCGC
CGCTCAAGGTCGGCATCATCGGCTTCACGCCGCCGGCCATCACCAGCTGGGACAAGCGCTGGCTCGACGGCAAGGTCTAC
ACCGTCGGCATCAAGGAGGCCGCGCAGCAGTACGTCCCGCAGATGCGCGCGCAGGGCGCCGACGTGGTGGTCGCCATCTC
GCACGGCGGGCTGGACAACTCGACGTACTCGCCGACGATGGAGAACGGCAGCTGGTGGCTCTCCACCGTGCCGGGCATCG
ACGCCATGCTGATCGGCCACTCGCACCAGCTGTTCCCGGATGCCAAGAGCACGGTCGGCCAGTTCAACCTGCCGGGGGTC
GACAAGGTCAATGGCACGGTCAACGGCGTGCCGACGGTGATGGCCAACTACTGGGGCAAGCACCTGGGCGTGATCCAGCT
CGGGCTGGTGTACGACGGCACGCACTGGTCGGTCGACAAGACCCAGACCACGGTGGAAGCGCGCCCGATCCAGAACGCCG
ACAAGACCTACGTCGCCGCCGACCCGGCCGTGTCCGCCGCGATCGCCGCCGAGCACCAGGCGACCATCGACTACGTGAAG
ACGCCGATCGGCAGCACCGACTTCCACATGAGCACGTTCTTCGCCGATGTGGGCGACCCGGGCGCGATCGAGATCGTCAA
CCAGGCGCAGGCGGATTCTGTGTCGGCCTACATCCAGGCCAACCTGCCGCAATACGCATCGCTGCCGGTGCTGTCGGTCA
GCGCGCCGTTCAAGAGCGGCTTCGGCGGCGGCACCGACTACACCGACGTCGCGGCCGGCTCGCTGGCCATCAACAACGCG
GCGGACCTGTACCTGTATCCGAACACGATCTACGCGGTCCTGGTCAGCGGCACCGACATCAAGAACTGGCTGGAGACGGC
AGCCAAGCGCTTCAACACCATCGACCCGACCAGCGCGACGGTGCAGAAGCTCGTCGGCACCTTCCCCGGCTACAACTTCG
ACATGTTCACCACGGCCGATCTCACCTACGAGATCGACGTGACGCAGGCAGTGGGCAGCCGCATCAAGAACCTGCAGTAC
AAGGGCGCGGCCATCGACCCGGCCGGCCAGTTCATCGTCGCCACCAACAACTACCGCGCCAGCGGCGGCGGCAACTTCCC
GGGCCTCGACGGCAGCAAGACCGTCTATGCCTCGCCGGACGCCAACCGCGACGTGCTGATCCGCTACATCAAGAAGCTCG
GCACCGTCACGCGCGCGGCCAACGGCTCGCAGCGCAGCTGGCGCTTCACCAGGCTGGCGAGTTCGGTGGCCCAGGTGCAG
TTCGCCTCCGCGCCCAACCGCCTGGCCGACGCTACGGCCGCGGGCCTGGCCGGCATCACGCAAGTCGCGGCGGATGACGG
CAGCGGCAAGGGCCTGGCGACATACCAGATCGACCTGACGCAATAA

Upstream 100 bases:

>100_bases
TGGCGCTGAGCCCCAGTCCGCCGTTCCCTCGCGTTGCGCAAACGATCGCGCCCGCGTGCCTTGCCATCCGCACACAAAAA
AAACATTCAGGGAGAAGTCC

Downstream 100 bases:

>100_bases
GGAGAGCACCCTACATGTCTTCGTTTCGTTCCGCATGGGCCGGTGCACCGGCCGGGATCGCGGTGGCGCGCACCGGCCAG
TCGGTGCCGCTGCTGAACGC

Product: 2',3'-cyclic-nucleotide 2'-phosphodiesterase precursor transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 681; Mature: 681

Protein sequence:

>681_residues
MQVRPLSSAALPLAAWLSLSLTACGGSDDPSAASAAPTGTKATLAVLETTDLHTNVLSYDYFKLAADSSLGFERVSTLIA
QARAQFPNTLLLDNGDTIQGTALSDYQALVNPIACGQALAIYKVMNAAGYDGGSIGNHEFNYGLPYLSQVTGNTFNVAGM
ADPAQQTRCAGPSFPQVLANVMSAKTSAPLFQPYTLLTKTVTATAPDGSTVSAPLKVGIIGFTPPAITSWDKRWLDGKVY
TVGIKEAAQQYVPQMRAQGADVVVAISHGGLDNSTYSPTMENGSWWLSTVPGIDAMLIGHSHQLFPDAKSTVGQFNLPGV
DKVNGTVNGVPTVMANYWGKHLGVIQLGLVYDGTHWSVDKTQTTVEARPIQNADKTYVAADPAVSAAIAAEHQATIDYVK
TPIGSTDFHMSTFFADVGDPGAIEIVNQAQADSVSAYIQANLPQYASLPVLSVSAPFKSGFGGGTDYTDVAAGSLAINNA
ADLYLYPNTIYAVLVSGTDIKNWLETAAKRFNTIDPTSATVQKLVGTFPGYNFDMFTTADLTYEIDVTQAVGSRIKNLQY
KGAAIDPAGQFIVATNNYRASGGGNFPGLDGSKTVYASPDANRDVLIRYIKKLGTVTRAANGSQRSWRFTRLASSVAQVQ
FASAPNRLADATAAGLAGITQVAADDGSGKGLATYQIDLTQ

Sequences:

>Translated_681_residues
MQVRPLSSAALPLAAWLSLSLTACGGSDDPSAASAAPTGTKATLAVLETTDLHTNVLSYDYFKLAADSSLGFERVSTLIA
QARAQFPNTLLLDNGDTIQGTALSDYQALVNPIACGQALAIYKVMNAAGYDGGSIGNHEFNYGLPYLSQVTGNTFNVAGM
ADPAQQTRCAGPSFPQVLANVMSAKTSAPLFQPYTLLTKTVTATAPDGSTVSAPLKVGIIGFTPPAITSWDKRWLDGKVY
TVGIKEAAQQYVPQMRAQGADVVVAISHGGLDNSTYSPTMENGSWWLSTVPGIDAMLIGHSHQLFPDAKSTVGQFNLPGV
DKVNGTVNGVPTVMANYWGKHLGVIQLGLVYDGTHWSVDKTQTTVEARPIQNADKTYVAADPAVSAAIAAEHQATIDYVK
TPIGSTDFHMSTFFADVGDPGAIEIVNQAQADSVSAYIQANLPQYASLPVLSVSAPFKSGFGGGTDYTDVAAGSLAINNA
ADLYLYPNTIYAVLVSGTDIKNWLETAAKRFNTIDPTSATVQKLVGTFPGYNFDMFTTADLTYEIDVTQAVGSRIKNLQY
KGAAIDPAGQFIVATNNYRASGGGNFPGLDGSKTVYASPDANRDVLIRYIKKLGTVTRAANGSQRSWRFTRLASSVAQVQ
FASAPNRLADATAAGLAGITQVAADDGSGKGLATYQIDLTQ
>Mature_681_residues
MQVRPLSSAALPLAAWLSLSLTACGGSDDPSAASAAPTGTKATLAVLETTDLHTNVLSYDYFKLAADSSLGFERVSTLIA
QARAQFPNTLLLDNGDTIQGTALSDYQALVNPIACGQALAIYKVMNAAGYDGGSIGNHEFNYGLPYLSQVTGNTFNVAGM
ADPAQQTRCAGPSFPQVLANVMSAKTSAPLFQPYTLLTKTVTATAPDGSTVSAPLKVGIIGFTPPAITSWDKRWLDGKVY
TVGIKEAAQQYVPQMRAQGADVVVAISHGGLDNSTYSPTMENGSWWLSTVPGIDAMLIGHSHQLFPDAKSTVGQFNLPGV
DKVNGTVNGVPTVMANYWGKHLGVIQLGLVYDGTHWSVDKTQTTVEARPIQNADKTYVAADPAVSAAIAAEHQATIDYVK
TPIGSTDFHMSTFFADVGDPGAIEIVNQAQADSVSAYIQANLPQYASLPVLSVSAPFKSGFGGGTDYTDVAAGSLAINNA
ADLYLYPNTIYAVLVSGTDIKNWLETAAKRFNTIDPTSATVQKLVGTFPGYNFDMFTTADLTYEIDVTQAVGSRIKNLQY
KGAAIDPAGQFIVATNNYRASGGGNFPGLDGSKTVYASPDANRDVLIRYIKKLGTVTRAANGSQRSWRFTRLASSVAQVQ
FASAPNRLADATAAGLAGITQVAADDGSGKGLATYQIDLTQ

Specific function: This bifunctional enzyme catalyzes two consecutive reactions during ribonucleic acid degradation. Converts a 2',3'- cyclic nucleotide to a 3'-nucleotide and then the 3'-nucleotide to the corresponding nucleoside and phosphate [H]

COG id: COG0737

COG function: function code F; 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5'-nucleotidase family [H]

Homologues:

Organism=Escherichia coli, GI1790658, Length=664, Percent_Identity=40.8132530120482, Blast_Score=451, Evalue=1e-128,
Organism=Escherichia coli, GI1786687, Length=578, Percent_Identity=23.356401384083, Blast_Score=89, Evalue=6e-19,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008334
- InterPro:   IPR006146
- InterPro:   IPR006179
- InterPro:   IPR006294
- InterPro:   IPR004843 [H]

Pfam domain/function: PF02872 5_nucleotid_C; PF00149 Metallophos [H]

EC number: =3.1.3.6; =3.1.4.16 [H]

Molecular weight: Translated: 71606; Mature: 71606

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00786 5_NUCLEOTIDASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVRPLSSAALPLAAWLSLSLTACGGSDDPSAASAAPTGTKATLAVLETTDLHTNVLSYD
CCCCCCCCHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCEEEEEEEECCCHHHHHCEE
YFKLAADSSLGFERVSTLIAQARAQFPNTLLLDNGDTIQGTALSDYQALVNPIACGQALA
EEEEECCCCCCHHHHHHHHHHHHHCCCCEEEECCCCEEECCCCHHHHHHHHHHHCCHHHH
IYKVMNAAGYDGGSIGNHEFNYGLPYLSQVTGNTFNVAGMADPAQQTRCAGPSFPQVLAN
HHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCEEEECCCCCHHHHHHCCCCCHHHHHHH
VMSAKTSAPLFQPYTLLTKTVTATAPDGSTVSAPLKVGIIGFTPPAITSWDKRWLDGKVY
HHHCCCCCCCCCCHHHHEEEEEEECCCCCEEECCEEEEEEECCCCCCCCCCHHHCCCEEE
TVGIKEAAQQYVPQMRAQGADVVVAISHGGLDNSTYSPTMENGSWWLSTVPGIDAMLIGH
EEEHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEECCCCEEEEECC
SHQLFPDAKSTVGQFNLPGVDKVNGTVNGVPTVMANYWGKHLGVIQLGLVYDGTHWSVDK
CCCCCCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEEEECCCEECCCC
TQTTVEARPIQNADKTYVAADPAVSAAIAAEHQATIDYVKTPIGSTDFHMSTFFADVGDP
CCEEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHEECCCCC
GAIEIVNQAQADSVSAYIQANLPQYASLPVLSVSAPFKSGFGGGTDYTDVAAGSLAINNA
CEEEEECCCCCCCEEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCHHHCCCCEEECCC
ADLYLYPNTIYAVLVSGTDIKNWLETAAKRFNTIDPTSATVQKLVGTFPGYNFDMFTTAD
CEEEEECCEEEEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEEEEEECC
LTYEIDVTQAVGSRIKNLQYKGAAIDPAGQFIVATNNYRASGGGNFPGLDGSKTVYASPD
EEEEEEHHHHHHHHHHCCEECCCEECCCCCEEEEECCEECCCCCCCCCCCCCCEEEECCC
ANRDVLIRYIKKLGTVTRAANGSQRSWRFTRLASSVAQVQFASAPNRLADATAAGLAGIT
CCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHH
QVAADDGSGKGLATYQIDLTQ
HHCCCCCCCCEEEEEEEEECC
>Mature Secondary Structure
MQVRPLSSAALPLAAWLSLSLTACGGSDDPSAASAAPTGTKATLAVLETTDLHTNVLSYD
CCCCCCCCHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCEEEEEEEECCCHHHHHCEE
YFKLAADSSLGFERVSTLIAQARAQFPNTLLLDNGDTIQGTALSDYQALVNPIACGQALA
EEEEECCCCCCHHHHHHHHHHHHHCCCCEEEECCCCEEECCCCHHHHHHHHHHHCCHHHH
IYKVMNAAGYDGGSIGNHEFNYGLPYLSQVTGNTFNVAGMADPAQQTRCAGPSFPQVLAN
HHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCEEEECCCCCHHHHHHCCCCCHHHHHHH
VMSAKTSAPLFQPYTLLTKTVTATAPDGSTVSAPLKVGIIGFTPPAITSWDKRWLDGKVY
HHHCCCCCCCCCCHHHHEEEEEEECCCCCEEECCEEEEEEECCCCCCCCCCHHHCCCEEE
TVGIKEAAQQYVPQMRAQGADVVVAISHGGLDNSTYSPTMENGSWWLSTVPGIDAMLIGH
EEEHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEECCCCEEEEECC
SHQLFPDAKSTVGQFNLPGVDKVNGTVNGVPTVMANYWGKHLGVIQLGLVYDGTHWSVDK
CCCCCCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEEEECCCEECCCC
TQTTVEARPIQNADKTYVAADPAVSAAIAAEHQATIDYVKTPIGSTDFHMSTFFADVGDP
CCEEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHEECCCCC
GAIEIVNQAQADSVSAYIQANLPQYASLPVLSVSAPFKSGFGGGTDYTDVAAGSLAINNA
CEEEEECCCCCCCEEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCHHHCCCCEEECCC
ADLYLYPNTIYAVLVSGTDIKNWLETAAKRFNTIDPTSATVQKLVGTFPGYNFDMFTTAD
CEEEEECCEEEEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEEEEEECC
LTYEIDVTQAVGSRIKNLQYKGAAIDPAGQFIVATNNYRASGGGNFPGLDGSKTVYASPD
EEEEEEHHHHHHHHHHCCEECCCEECCCCCEEEEECCEECCCCCCCCCCCCCCEEEECCC
ANRDVLIRYIKKLGTVTRAANGSQRSWRFTRLASSVAQVQFASAPNRLADATAAGLAGIT
CCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHH
QVAADDGSGKGLATYQIDLTQ
HHCCCCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3005231; 7610040; 9278503; 2172762; 9298646 [H]