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The map label for this gene is 17548078

Identifier: 17548078

GI number: 17548078

Start: 3620028

End: 3621005

Strand: Direct

Name: 17548078

Synonym: RSc3361

Alternate gene names: NA

Gene position: 3620028-3621005 (Clockwise)

Preceding gene: 17548077

Following gene: 17548081

Centisome position: 97.41

GC content: 70.86

Gene sequence:

>978_bases
ATGACACGCATCTGTATCGTGGGCGCCGGCGCGGTCGGCGGCTATCTGGGCGCTCGGCTGGCGCAGGCCGGCGAGGCTGT
CAACGTGCTGGCGCGCGGCGCCACGCTGCAAGCGCTGCAGACCGTCGGCCTATGCCTGACCGAAGATGGCGTCACGCACA
CGCTGCCCGTCCATGTAACGGATACTGCCGCAGCGCTTGGCGTGCAGGACCTCGTGATCGTTGCGGTCAAGGCGCCGGCC
CTGGAGAACGTGGCCGCCGGCATCGCGCCGCTGATCGGCCCCGACACCTGCGTGGTGGTGGCGATGAATGGAGTGCCGTG
GTGGTTTTTCGAGCGCGCCGGTCCGCTGCAGGGCCTGCGCTTGCAGGCCGTCGACCCGCACGGCTGCATTGCGCGGGCGA
TCCCGACCCGGCACGTACTGGGCTGCGTGGTGCACCTGACGTGCTCCACCGCATCGCCCGGCCATGTCCGGCACGGTAGC
GGCCGGCGGCTGATTCTCGGGGAGCCGGCCGGCGGCCCTTCGCCGCGCCTGGCGGCCGTTGCCGCACGGTTCGAGCGCGC
GGGTCTCCAGGTCGAGTGCAGCGATGCGATCCAGCGCGACATCTGGTTCAAGCTGTGGGGCAACATGACCATGAACCCGG
TCTCGGTGCTGACCGGTGCCACGTGCGACCGCATCCTCGACGACCCGCAGGTGTCGGCCTTCTGCCTGGCGGTGATGGAC
GAAGCCAAGGCGATCGGCGCGCGCATCGGCTGCCCGATCGCGCAGAGCGGCGAGGCGCGCTGCGCGGTGACCCGCCAGCT
GGGCGTCTTCAAGACCTCGATGCTGCAGGATGCCGAAGCCGGGCGCGGCCCGCTGGAGATCGATGCGCTGGTGGCCTCGG
TGCGCGAGATCAGCCAGCACGTGGGCGTGCCGACCCCGCGGATCGATGCGTTGCTGGGCCTGGTGCGCCTGCACGCCCAG
ACCCGCGGACTCTACTGA

Upstream 100 bases:

>100_bases
ACGCGGACCCCGATGCGGGCGAGGCTGCGCTCGCGGCACAGCTCCGCGCGGCCGCATCGATCTACCCCGTCGTTCGTGGC
CCTTGCTTTGGGATCGACTG

Downstream 100 bases:

>100_bases
TCCGATCGATCCCGATCGACTGCCGCGACGGCGTGCCTACGGCGTCAGCGCTGGGTGCTTCAGTGCGTGCGCGGTTTCGA
GCCACTGCTTGCGGAAGGCG

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MTRICIVGAGAVGGYLGARLAQAGEAVNVLARGATLQALQTVGLCLTEDGVTHTLPVHVTDTAAALGVQDLVIVAVKAPA
LENVAAGIAPLIGPDTCVVVAMNGVPWWFFERAGPLQGLRLQAVDPHGCIARAIPTRHVLGCVVHLTCSTASPGHVRHGS
GRRLILGEPAGGPSPRLAAVAARFERAGLQVECSDAIQRDIWFKLWGNMTMNPVSVLTGATCDRILDDPQVSAFCLAVMD
EAKAIGARIGCPIAQSGEARCAVTRQLGVFKTSMLQDAEAGRGPLEIDALVASVREISQHVGVPTPRIDALLGLVRLHAQ
TRGLY

Sequences:

>Translated_325_residues
MTRICIVGAGAVGGYLGARLAQAGEAVNVLARGATLQALQTVGLCLTEDGVTHTLPVHVTDTAAALGVQDLVIVAVKAPA
LENVAAGIAPLIGPDTCVVVAMNGVPWWFFERAGPLQGLRLQAVDPHGCIARAIPTRHVLGCVVHLTCSTASPGHVRHGS
GRRLILGEPAGGPSPRLAAVAARFERAGLQVECSDAIQRDIWFKLWGNMTMNPVSVLTGATCDRILDDPQVSAFCLAVMD
EAKAIGARIGCPIAQSGEARCAVTRQLGVFKTSMLQDAEAGRGPLEIDALVASVREISQHVGVPTPRIDALLGLVRLHAQ
TRGLY
>Mature_324_residues
TRICIVGAGAVGGYLGARLAQAGEAVNVLARGATLQALQTVGLCLTEDGVTHTLPVHVTDTAAALGVQDLVIVAVKAPAL
ENVAAGIAPLIGPDTCVVVAMNGVPWWFFERAGPLQGLRLQAVDPHGCIARAIPTRHVLGCVVHLTCSTASPGHVRHGSG
RRLILGEPAGGPSPRLAAVAARFERAGLQVECSDAIQRDIWFKLWGNMTMNPVSVLTGATCDRILDDPQVSAFCLAVMDE
AKAIGARIGCPIAQSGEARCAVTRQLGVFKTSMLQDAEAGRGPLEIDALVASVREISQHVGVPTPRIDALLGLVRLHAQT
RGLY

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 33893; Mature: 33762

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRICIVGAGAVGGYLGARLAQAGEAVNVLARGATLQALQTVGLCLTEDGVTHTLPVHVT
CCEEEEEECCHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHCEEEECCCCCEEEEEEEE
DTAAALGVQDLVIVAVKAPALENVAAGIAPLIGPDTCVVVAMNGVPWWFFERAGPLQGLR
CHHHHHCCCEEEEEEECCCCHHHHHHHHHHCCCCCCEEEEEECCCCEEEEECCCCCCCCE
LQAVDPHGCIARAIPTRHVLGCVVHLTCSTASPGHVRHGSGRRLILGEPAGGPSPRLAAV
EEEECCCCHHHHHCCHHHHHEEEEEEEECCCCCCCEECCCCCEEEEECCCCCCCCHHHHH
AARFERAGLQVECSDAIQRDIWFKLWGNMTMNPVSVLTGATCDRILDDPQVSAFCLAVMD
HHHHHHCCCEEEEHHHHHHHHHHHECCCCCCCHHHHHHCCHHHHHCCCCCHHHHHHHHHH
EAKAIGARIGCPIAQSGEARCAVTRQLGVFKTSMLQDAEAGRGPLEIDALVASVREISQH
HHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
VGVPTPRIDALLGLVRLHAQTRGLY
CCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TRICIVGAGAVGGYLGARLAQAGEAVNVLARGATLQALQTVGLCLTEDGVTHTLPVHVT
CEEEEEECCHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHCEEEECCCCCEEEEEEEE
DTAAALGVQDLVIVAVKAPALENVAAGIAPLIGPDTCVVVAMNGVPWWFFERAGPLQGLR
CHHHHHCCCEEEEEEECCCCHHHHHHHHHHCCCCCCEEEEEECCCCEEEEECCCCCCCCE
LQAVDPHGCIARAIPTRHVLGCVVHLTCSTASPGHVRHGSGRRLILGEPAGGPSPRLAAV
EEEECCCCHHHHHCCHHHHHEEEEEEEECCCCCCCEECCCCCEEEEECCCCCCCCHHHHH
AARFERAGLQVECSDAIQRDIWFKLWGNMTMNPVSVLTGATCDRILDDPQVSAFCLAVMD
HHHHHHCCCEEEEHHHHHHHHHHHECCCCCCCHHHHHHCCHHHHHCCCCCHHHHHHHHHH
EAKAIGARIGCPIAQSGEARCAVTRQLGVFKTSMLQDAEAGRGPLEIDALVASVREISQH
HHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
VGVPTPRIDALLGLVRLHAQTRGLY
CCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]