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The map label for this gene is minC

Identifier: 17548081

GI number: 17548081

Start: 3624216

End: 3624983

Strand: Direct

Name: minC

Synonym: RSc3364

Alternate gene names: 17548081

Gene position: 3624216-3624983 (Clockwise)

Preceding gene: 17548078

Following gene: 17548082

Centisome position: 97.52

GC content: 70.83

Gene sequence:

>768_bases
ATGTCCCAGAAGAAAGCGCCGCTGTTCGAGATCCGCAGTGGCACCGTCGATGCCCTGCTGTTGTCGCCGCGCACTGCCGA
CATGGACGCCCTGGCCGCCGAGCTCACGCGGCGCTTTGCCGACACGCCGGAGTTTTTCTCCAACGACGTGATCGCCATCG
ACGTGCGCCGCCTGGCCGCCGATGAACGCCTGCCCATCGACCGTCTGGTGGAGACCCTGACCGGGCTGCGCGCCCGCGCC
ATCGGCGTGGTGGCGAGCCCCGAGCAGGCCGAATGGGCCCAGGCCTGCGGCCTGCCGCTGCTGGACAGCCACGGCCGCCG
CCCGCGCGGCGAGCGCAGCGAAGAGGCCGCCGAGGCGGTGCCCGCTGCCGCCGAGCCCGTTCCGGCACCCGCGGCATCGC
CCGCCCCGCCGGTCGAAGCCGTGGCCATGCAGCCTGGCGCGATGATCATCGAGAAGCCCCTGCGCTCCGGCCAGCGCGTC
TATGCGCGCGGCGACCTGGTCGTGCTCGACCTGGTGAGCGACGGCGCCGAGGTGATCGCCGAGGGCAACATCTACGTGTA
TGCCTCGCTGCGCGGCCGCGCGCTGGCGGGGGTGAAGGGCAATCTGGACGCGCGCATCTTCTGCACGTGCCTGGAGCCCC
AGCTGATTTCCATCGCCGGCATCTACCGCACCGGCGAAACCCCGTGGCCGGAAGCGTTCGCGAGCAAGCCCGCGCAGATC
CGGCTGTCGGAGAACACGCTGGTTCTCGAACCGTTGCGGATGAAATGA

Upstream 100 bases:

>100_bases
GGCGCGGGTCTCCCCCGAATGGGGGGCGCGCGTGGCCAAAAAATCCGGTAAGGCCCCTCAACAACGTTAGAATGGGCCAC
TTTTTCCGCGTAGCCGTTCT

Downstream 100 bases:

>100_bases
CGCGCCCCGTGCGTGCCGAGCGACTTAACTTTCAGATAGACGAACCATGACCAAGATCATCGTAGTCACCTCCGGCAAGG
GCGGTGTCGGCAAGACGACC

Product: septum formation inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MSQKKAPLFEIRSGTVDALLLSPRTADMDALAAELTRRFADTPEFFSNDVIAIDVRRLAADERLPIDRLVETLTGLRARA
IGVVASPEQAEWAQACGLPLLDSHGRRPRGERSEEAAEAVPAAAEPVPAPAASPAPPVEAVAMQPGAMIIEKPLRSGQRV
YARGDLVVLDLVSDGAEVIAEGNIYVYASLRGRALAGVKGNLDARIFCTCLEPQLISIAGIYRTGETPWPEAFASKPAQI
RLSENTLVLEPLRMK

Sequences:

>Translated_255_residues
MSQKKAPLFEIRSGTVDALLLSPRTADMDALAAELTRRFADTPEFFSNDVIAIDVRRLAADERLPIDRLVETLTGLRARA
IGVVASPEQAEWAQACGLPLLDSHGRRPRGERSEEAAEAVPAAAEPVPAPAASPAPPVEAVAMQPGAMIIEKPLRSGQRV
YARGDLVVLDLVSDGAEVIAEGNIYVYASLRGRALAGVKGNLDARIFCTCLEPQLISIAGIYRTGETPWPEAFASKPAQI
RLSENTLVLEPLRMK
>Mature_254_residues
SQKKAPLFEIRSGTVDALLLSPRTADMDALAAELTRRFADTPEFFSNDVIAIDVRRLAADERLPIDRLVETLTGLRARAI
GVVASPEQAEWAQACGLPLLDSHGRRPRGERSEEAAEAVPAAAEPVPAPAASPAPPVEAVAMQPGAMIIEKPLRSGQRVY
ARGDLVVLDLVSDGAEVIAEGNIYVYASLRGRALAGVKGNLDARIFCTCLEPQLISIAGIYRTGETPWPEAFASKPAQIR
LSENTLVLEPLRMK

Specific function: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize ftsZ filaments that have formed before they mature into polar Z rings. Prevents ftsZ polymerization

COG id: COG0850

COG function: function code D; Septum formation inhibitor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minC family

Homologues:

Organism=Escherichia coli, GI1787424, Length=246, Percent_Identity=30.8943089430894, Blast_Score=112, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MINC_RALSO (Q8XU30)

Other databases:

- EMBL:   AL646052
- RefSeq:   NP_521483.1
- ProteinModelPortal:   Q8XU30
- GeneID:   1222228
- GenomeReviews:   AL646052_GR
- KEGG:   rso:RSc3364
- NMPDR:   fig|267608.1.peg.3362
- HOGENOM:   HBG399077
- OMA:   PEFFAND
- ProtClustDB:   PRK01973
- BioCyc:   RSOL267608:RSC3364-MONOMER
- HAMAP:   MF_00267
- InterPro:   IPR016098
- InterPro:   IPR013033
- InterPro:   IPR007874
- InterPro:   IPR005526
- Gene3D:   G3DSA:2.160.20.70
- TIGRFAMs:   TIGR01222

Pfam domain/function: PF03775 MinC_C; PF05209 MinC_N; SSF63848 MinC_C

EC number: NA

Molecular weight: Translated: 27401; Mature: 27270

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQKKAPLFEIRSGTVDALLLSPRTADMDALAAELTRRFADTPEFFSNDVIAIDVRRLAA
CCCCCCCEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHCCCEEEEEEHHHHC
DERLPIDRLVETLTGLRARAIGVVASPEQAEWAQACGLPLLDSHGRRPRGERSEEAAEAV
CCCCCHHHHHHHHHCCHHHEEEEEECCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHC
PAAAEPVPAPAASPAPPVEAVAMQPGAMIIEKPLRSGQRVYARGDLVVLDLVSDGAEVIA
CCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHCCCCEEEECCCEEEEEECCCCCEEEE
EGNIYVYASLRGRALAGVKGNLDARIFCTCLEPQLISIAGIYRTGETPWPEAFASKPAQI
CCCEEEEEECCCCEEECCCCCCCEEEEEEECCCCEEEEEEEEECCCCCCCHHHHCCCCEE
RLSENTLVLEPLRMK
EECCCEEEECCCCCC
>Mature Secondary Structure 
SQKKAPLFEIRSGTVDALLLSPRTADMDALAAELTRRFADTPEFFSNDVIAIDVRRLAA
CCCCCCEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHCCCEEEEEEHHHHC
DERLPIDRLVETLTGLRARAIGVVASPEQAEWAQACGLPLLDSHGRRPRGERSEEAAEAV
CCCCCHHHHHHHHHCCHHHEEEEEECCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHC
PAAAEPVPAPAASPAPPVEAVAMQPGAMIIEKPLRSGQRVYARGDLVVLDLVSDGAEVIA
CCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHCCCCEEEECCCEEEEEECCCCCEEEE
EGNIYVYASLRGRALAGVKGNLDARIFCTCLEPQLISIAGIYRTGETPWPEAFASKPAQI
CCCEEEEEECCCCEEECCCCCCCEEEEEEECCCCEEEEEEEEECCCCCCCHHHHCCCCEE
RLSENTLVLEPLRMK
EECCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852