Click here to switch to the map view.

The map label for this gene is phhB

Identifier: 17548073

GI number: 17548073

Start: 3616528

End: 3616833

Strand: Direct

Name: phhB

Synonym: RSc3356

Alternate gene names: 17548073

Gene position: 3616528-3616833 (Clockwise)

Preceding gene: 17548072

Following gene: 17548076

Centisome position: 97.31

GC content: 62.09

Gene sequence:

>306_bases
ATGATGCCGACTCTCAATGACGAACAACGCAAGGCCCTGTTTGCCGAACTGCCGGGCTGGTCGCTGCAGAACGACCGCGA
TGCGATCCACAAGCGCTTCACCTTCACCGACTTCAACGCCGCGTTCGGCTTCATGACGCGCGTGGCGCTCAAGGCCGAGC
AGGTGAATCACCATCCGGAGTGGTTCAATGTGTGGAATCGCGTGGACATCACGCTGTCCACGCACGATGCCAACGGCCTC
ACGCACCGCGATGCGGATCTCGCGCGCTTCATCGAGCAGGCCGCGCAGCTGACCGGCGCCAAGTAA

Upstream 100 bases:

>100_bases
CCGTGCTCAACGCCGGCACCCGCGAGGGCTGGGCCGACACGGCGGATATCTGAGCGCTGGCTATACTGCGCGCATTCCCA
TCCGCCATCGACCCGAGACC

Downstream 100 bases:

>100_bases
GCCGATCCGGTTTCCTTACGCGCCCGTTGCGGCGCGCCACGCCTCGAACGCCGCCCGCGCTTTTTCGCTCAGCTGTTCCG
GAGCGATGCGGGTGGCGCCT

Product: pterin-4-alpha-carbinolamine dehydratase

Products: NA

Alternate protein names: PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Pterin carbinolamine dehydratase; PCD

Number of amino acids: Translated: 101; Mature: 101

Protein sequence:

>101_residues
MMPTLNDEQRKALFAELPGWSLQNDRDAIHKRFTFTDFNAAFGFMTRVALKAEQVNHHPEWFNVWNRVDITLSTHDANGL
THRDADLARFIEQAAQLTGAK

Sequences:

>Translated_101_residues
MMPTLNDEQRKALFAELPGWSLQNDRDAIHKRFTFTDFNAAFGFMTRVALKAEQVNHHPEWFNVWNRVDITLSTHDANGL
THRDADLARFIEQAAQLTGAK
>Mature_101_residues
MMPTLNDEQRKALFAELPGWSLQNDRDAIHKRFTFTDFNAAFGFMTRVALKAEQVNHHPEWFNVWNRVDITLSTHDANGL
THRDADLARFIEQAAQLTGAK

Specific function: Unknown

COG id: COG2154

COG function: function code H; Pterin-4a-carbinolamine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pterin-4-alpha-carbinolamine dehydratase family

Homologues:

Organism=Homo sapiens, GI134133240, Length=93, Percent_Identity=56.989247311828, Blast_Score=115, Evalue=6e-27,
Organism=Homo sapiens, GI4557831, Length=93, Percent_Identity=60.2150537634409, Blast_Score=113, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI115533705, Length=97, Percent_Identity=57.7319587628866, Blast_Score=119, Evalue=3e-28,
Organism=Drosophila melanogaster, GI45549100, Length=99, Percent_Identity=51.5151515151515, Blast_Score=108, Evalue=8e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PHS_RALSO (Q8XU38)

Other databases:

- EMBL:   AL646052
- RefSeq:   NP_521475.1
- ProteinModelPortal:   Q8XU38
- SMR:   Q8XU38
- GeneID:   1222220
- GenomeReviews:   AL646052_GR
- KEGG:   rso:RSc3356
- NMPDR:   fig|267608.1.peg.3354
- HOGENOM:   HBG705804
- OMA:   SEERKTR
- ProtClustDB:   PRK00823
- BioCyc:   RSOL267608:RSC3356-MONOMER
- BRENDA:   4.2.1.96
- HAMAP:   MF_00434
- InterPro:   IPR001533
- Gene3D:   G3DSA:3.30.1360.20
- PANTHER:   PTHR12599

Pfam domain/function: PF01329 Pterin_4a; SSF55248 Trans_pterinDh

EC number: =4.2.1.96

Molecular weight: Translated: 11626; Mature: 11626

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMPTLNDEQRKALFAELPGWSLQNDRDAIHKRFTFTDFNAAFGFMTRVALKAEQVNHHPE
CCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCH
WFNVWNRVDITLSTHDANGLTHRDADLARFIEQAAQLTGAK
HHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MMPTLNDEQRKALFAELPGWSLQNDRDAIHKRFTFTDFNAAFGFMTRVALKAEQVNHHPE
CCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCH
WFNVWNRVDITLSTHDANGLTHRDADLARFIEQAAQLTGAK
HHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852