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The map label for this gene is hmrR2 [H]

Identifier: 17548064

GI number: 17548064

Start: 3608103

End: 3608582

Strand: Reverse

Name: hmrR2 [H]

Synonym: RSc3347

Alternate gene names: 17548064

Gene position: 3608582-3608103 (Counterclockwise)

Preceding gene: 17548065

Following gene: 17548063

Centisome position: 97.1

GC content: 70.0

Gene sequence:

>480_bases
ATGACCCGTGCCGACCTGAACGATGCATCGCAAGACGGCCCCGTCAACATCGGCGAGGCGGCCAGGGCCAGCGGCGTGTC
GGCCAAGATGATCCGCTACTACGAGCGCATCGGTCTGCTGCCGCCCAGCCCGCGCACCGAGGGCAACTACCGGGTCTATG
ATCCGCGCGCGCTGCACGTGCTGCGGTTCATCCACCGGGCGCGTTCGCTCGGGTTTTCGCTCGAAGAGATTCGCACGCTG
CTCTCGCTGTGGCACGACCGCGCGCGCGCCAGCGCCGACGTGAAGGCCATCACGCTGCGCCACGTGGCCGACCTCGACGC
GCGCATCCGCGAGCTGCAAGGCATGCGCGATACGCTGGTGACGCTCGCCGATGCCTGCCATGGCGACGACCGCCCGGACT
GCCCGATCCTCGAGGGCGTGGCCGGGGAGGCTTCGCCCTGCTGCGATGCAGCGCTGCCCGATCCGGACCGACACGGCTGA

Upstream 100 bases:

>100_bases
CGGCGATGGCGTTCTCCAGCGTGAGCGTCGTCACCAACGCGCTGATGCTGCGGCGCTGGCACCCGCGCTGGGAAACCGCC
ACCGCCGGGGGAGACCGCGC

Downstream 100 bases:

>100_bases
CCATCGCGGCGCGCGGCGTCTATGCCACAATCAGGCAACCCAACGAGGAGACGCCCATGACGCAAGCCCCCGCCACGGTC
GATGCGCTGGAGACGCGCCA

Product: transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MTRADLNDASQDGPVNIGEAARASGVSAKMIRYYERIGLLPPSPRTEGNYRVYDPRALHVLRFIHRARSLGFSLEEIRTL
LSLWHDRARASADVKAITLRHVADLDARIRELQGMRDTLVTLADACHGDDRPDCPILEGVAGEASPCCDAALPDPDRHG

Sequences:

>Translated_159_residues
MTRADLNDASQDGPVNIGEAARASGVSAKMIRYYERIGLLPPSPRTEGNYRVYDPRALHVLRFIHRARSLGFSLEEIRTL
LSLWHDRARASADVKAITLRHVADLDARIRELQGMRDTLVTLADACHGDDRPDCPILEGVAGEASPCCDAALPDPDRHG
>Mature_158_residues
TRADLNDASQDGPVNIGEAARASGVSAKMIRYYERIGLLPPSPRTEGNYRVYDPRALHVLRFIHRARSLGFSLEEIRTLL
SLWHDRARASADVKAITLRHVADLDARIRELQGMRDTLVTLADACHGDDRPDCPILEGVAGEASPCCDAALPDPDRHG

Specific function: Transcriptional regulator involved in acid tolerance. Binds copper [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786695, Length=134, Percent_Identity=46.2686567164179, Blast_Score=127, Evalue=4e-31,
Organism=Escherichia coli, GI1789687, Length=138, Percent_Identity=41.304347826087, Blast_Score=93, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011789
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 17510; Mature: 17379

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRADLNDASQDGPVNIGEAARASGVSAKMIRYYERIGLLPPSPRTEGNYRVYDPRALHV
CCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCEEEECHHHHHH
LRFIHRARSLGFSLEEIRTLLSLWHDRARASADVKAITLRHVADLDARIRELQGMRDTLV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLADACHGDDRPDCPILEGVAGEASPCCDAALPDPDRHG
HHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TRADLNDASQDGPVNIGEAARASGVSAKMIRYYERIGLLPPSPRTEGNYRVYDPRALHV
CCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCEEEECHHHHHH
LRFIHRARSLGFSLEEIRTLLSLWHDRARASADVKAITLRHVADLDARIRELQGMRDTLV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLADACHGDDRPDCPILEGVAGEASPCCDAALPDPDRHG
HHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481431 [H]