Click here to switch to the map view.

The map label for this gene is fabG [C]

Identifier: 17548048

GI number: 17548048

Start: 3593959

End: 3594564

Strand: Reverse

Name: fabG [C]

Synonym: RSc3331

Alternate gene names: 17548048

Gene position: 3594564-3593959 (Counterclockwise)

Preceding gene: 17548051

Following gene: 17548047

Centisome position: 96.72

GC content: 68.15

Gene sequence:

>606_bases
ATGAAAATCATCGTGATCGGTGCCAGCGGCACCATCGGCCGTGCCGTGACGGCCGAACTGGAGCAGGGCGGGGCGCATGA
GGTCATCCGCGTCGGTCGCACGCGAGGCGATCACCAGGTCGACATCACCAACGCCGACAGCGTGGCGGCGCTCTTCGCCA
AGCTCGGCCGCGTGGACGCCATCGTCTCCACGGCCGGCAACCTGTTCTTCGGCCCACTCACGCGAATGAGCGCCGCGGAT
TTCAACCTCGGCCTGCAAGACAAGCTGCTCGGGCAGGTGCGGCTTGCGTTGGTCGGCCAGCACCACCTGAACGACGGCGG
CTCGATCACGCTGACTACCGGTATCGTCGGCCAGGAGCCGATCGCGCAGGGCGCCAACGCGACCGCGGTGAATGCCGGCA
TCGAAGGCTTCGTGCGGGCGGCCGCCTGTGAGTTGCCGCGAGGCATCCGCATCAACGCCGTCAGCCCGACCGTGCTGACC
GAATCGATGGCGGTGTACGGCCCGTTCTTTCCCGGCTTCGAAAGCGTGCCGGCGGCGCGCGCCGCGATGGCATATCGGCG
CAGCGTGGAAGGGGTGCAGAGCGGGCGGGTCTATCGGGTCGGCTGA

Upstream 100 bases:

>100_bases
ACTGCTGATTAGGAATAGACAAAGTTACCACGGCTTTATCGCTCTGTGGGTTCGGCCAACAATGCGTGTCATTCCAAACT
GATTCGCAAAGGAGCGCAGC

Downstream 100 bases:

>100_bases
CCGGGCGACCGGTGTGCAGGTCGGTTAAGCTCCAGCGGTCCCGACTGCTGGAGCGAGACGTGAGGCAGTGGCCGCTGGCG
ATGATGATGGGTGCCTTGGT

Product: short chain dehydrogenase

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: Short-Chain Dehydrogenase/Reductase SDR; Short-Chain Dehydrogenase; Dehydrogenase; Short-Chain Dehydrogenase Protein; 3-Oxoacyl-[Acyl-Carrier-Protein] Reductase; NAD-Dependent Epimerase/Dehydratase; Oxidoreductase; Aklaviketone Reductase; Short Chain Dehydrogenase/Reductase Family Oxidoreductase; DTDP-4-Dehydrorhamnose Reductase; Short Chain Dehydrogenase Family Protein; Dehydrogenases With Different Specificities; Oxidoreductase Short Chain Dehydrogenase/Reductase Family

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MKIIVIGASGTIGRAVTAELEQGGAHEVIRVGRTRGDHQVDITNADSVAALFAKLGRVDAIVSTAGNLFFGPLTRMSAAD
FNLGLQDKLLGQVRLALVGQHHLNDGGSITLTTGIVGQEPIAQGANATAVNAGIEGFVRAAACELPRGIRINAVSPTVLT
ESMAVYGPFFPGFESVPAARAAMAYRRSVEGVQSGRVYRVG

Sequences:

>Translated_201_residues
MKIIVIGASGTIGRAVTAELEQGGAHEVIRVGRTRGDHQVDITNADSVAALFAKLGRVDAIVSTAGNLFFGPLTRMSAAD
FNLGLQDKLLGQVRLALVGQHHLNDGGSITLTTGIVGQEPIAQGANATAVNAGIEGFVRAAACELPRGIRINAVSPTVLT
ESMAVYGPFFPGFESVPAARAAMAYRRSVEGVQSGRVYRVG
>Mature_201_residues
MKIIVIGASGTIGRAVTAELEQGGAHEVIRVGRTRGDHQVDITNADSVAALFAKLGRVDAIVSTAGNLFFGPLTRMSAAD
FNLGLQDKLLGQVRLALVGQHHLNDGGSITLTTGIVGQEPIAQGANATAVNAGIEGFVRAAACELPRGIRINAVSPTVLT
ESMAVYGPFFPGFESVPAARAAMAYRRSVEGVQSGRVYRVG

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 20868; Mature: 20868

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIVIGASGTIGRAVTAELEQGGAHEVIRVGRTRGDHQVDITNADSVAALFAKLGRVDA
CEEEEEECCCCCCHHEEHHHHCCCHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHH
IVSTAGNLFFGPLTRMSAADFNLGLQDKLLGQVRLALVGQHHLNDGGSITLTTGIVGQEP
HHHHCCCEEECCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCH
IAQGANATAVNAGIEGFVRAAACELPRGIRINAVSPTVLTESMAVYGPFFPGFESVPAAR
HHCCCCCEEECCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCHHHH
AAMAYRRSVEGVQSGRVYRVG
HHHHHHHHHHHHHCCEEEECC
>Mature Secondary Structure
MKIIVIGASGTIGRAVTAELEQGGAHEVIRVGRTRGDHQVDITNADSVAALFAKLGRVDA
CEEEEEECCCCCCHHEEHHHHCCCHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHH
IVSTAGNLFFGPLTRMSAADFNLGLQDKLLGQVRLALVGQHHLNDGGSITLTTGIVGQEP
HHHHCCCEEECCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCH
IAQGANATAVNAGIEGFVRAAACELPRGIRINAVSPTVLTESMAVYGPFFPGFESVPAAR
HHCCCCCEEECCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCHHHH
AAMAYRRSVEGVQSGRVYRVG
HHHHHHHHHHHHHCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA