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The map label for this gene is ycbL [H]

Identifier: 17547985

GI number: 17547985

Start: 3519959

End: 3520633

Strand: Direct

Name: ycbL [H]

Synonym: RSc3268

Alternate gene names: 17547985

Gene position: 3519959-3520633 (Clockwise)

Preceding gene: 17547983

Following gene: 17547986

Centisome position: 94.71

GC content: 69.33

Gene sequence:

>675_bases
ATGTGCACAAAAAACCACATGAAAGTCGTCGTCGTCCCGGTTACGCCGTTTGAACAGAACTGCACGCTGCTGATCGGCGA
CGACGGGCGCGCCGCCGTCACCGACCCCGGCGGCGACATCGACCGCATCCTGAGCGCGGCCCGCCAGCAAGGCGCCCGCA
TCGAAAAGATCCTGCTCACGCACGGCCACGTGGACCACTGCGCCGCCGCCGACGCCCTGCGCACCCAGCTCGGCGTACCC
ATCGAAGGGCCGCACAGGGACGAGGCGTTCTGGATCGACCAACTGCCGACGCAAAGCCAGCGCTTCGGCTTCCCGCCCGC
CCGCGCCTTCGTGCCCGACCGCTGGCTGGACGACGGCGACACGGTGGAAGCCGCCGGCCGCACGCTCGAAGTGTTCCACT
GCCCCGGCCACACGCCGGGCCACGTGGTCTTCTTCAGCCGGCCGGACCGCATCGCCATCGTCGGCGACGTGCTGTTCGCG
GGCTCGATCGGCCGCACGGATTTTCCGCGCGGCAACCACGCGGACCTGATCCGCTCGATCCGCACCAAGCTGTGGCCGCT
CGGCGACGATGTGACCTTCGTGCCGGGCCACGGCCCCGTTTCCACCTTCGGCGACGAGCGCGCGACCAATCCGTATGTCG
CCGACCGCCTGTTCGCCGATGAGGGCACCGCATGA

Upstream 100 bases:

>100_bases
ACTTTGTAAAAGTTTTGCCCAGTGCCGTGCCGATGGCCCGCCAGCCCAGTGCCGGCGCGGGCTGGGGCCGATACAATCGG
CCTGTTCCCTTATTGCACCG

Downstream 100 bases:

>100_bases
GCGACGATACCGCCGCGGACGCCGCCCCGGTCGACAAGCCCCGCCGCAAGCGCGGCAACCAGCCGCCCGACACCCGGCCG
GAAATCTACGTCAGCACCGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MCTKNHMKVVVVPVTPFEQNCTLLIGDDGRAAVTDPGGDIDRILSAARQQGARIEKILLTHGHVDHCAAADALRTQLGVP
IEGPHRDEAFWIDQLPTQSQRFGFPPARAFVPDRWLDDGDTVEAAGRTLEVFHCPGHTPGHVVFFSRPDRIAIVGDVLFA
GSIGRTDFPRGNHADLIRSIRTKLWPLGDDVTFVPGHGPVSTFGDERATNPYVADRLFADEGTA

Sequences:

>Translated_224_residues
MCTKNHMKVVVVPVTPFEQNCTLLIGDDGRAAVTDPGGDIDRILSAARQQGARIEKILLTHGHVDHCAAADALRTQLGVP
IEGPHRDEAFWIDQLPTQSQRFGFPPARAFVPDRWLDDGDTVEAAGRTLEVFHCPGHTPGHVVFFSRPDRIAIVGDVLFA
GSIGRTDFPRGNHADLIRSIRTKLWPLGDDVTFVPGHGPVSTFGDERATNPYVADRLFADEGTA
>Mature_224_residues
MCTKNHMKVVVVPVTPFEQNCTLLIGDDGRAAVTDPGGDIDRILSAARQQGARIEKILLTHGHVDHCAAADALRTQLGVP
IEGPHRDEAFWIDQLPTQSQRFGFPPARAFVPDRWLDDGDTVEAAGRTLEVFHCPGHTPGHVVFFSRPDRIAIVGDVLFA
GSIGRTDFPRGNHADLIRSIRTKLWPLGDDVTFVPGHGPVSTFGDERATNPYVADRLFADEGTA

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=208, Percent_Identity=30.7692307692308, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1787158, Length=212, Percent_Identity=50.9433962264151, Blast_Score=235, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI17538952, Length=197, Percent_Identity=28.9340101522843, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 24420; Mature: 24420

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCTKNHMKVVVVPVTPFEQNCTLLIGDDGRAAVTDPGGDIDRILSAARQQGARIEKILLT
CCCCCCCEEEEEECCCCCCCCEEEECCCCCEEEECCCCCHHHHHHHHHHCCCCEEEEEEE
HGHVDHCAAADALRTQLGVPIEGPHRDEAFWIDQLPTQSQRFGFPPARAFVPDRWLDDGD
CCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCHHCCCCCHHCCCCCCCCCCCC
TVEAAGRTLEVFHCPGHTPGHVVFFSRPDRIAIVGDVLFAGSIGRTDFPRGNHADLIRSI
EEHHCCCEEEEEECCCCCCCEEEEEECCCEEEEEEEEEEECCCCCCCCCCCCHHHHHHHH
RTKLWPLGDDVTFVPGHGPVSTFGDERATNPYVADRLFADEGTA
HHHHCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHEEECCCCCC
>Mature Secondary Structure
MCTKNHMKVVVVPVTPFEQNCTLLIGDDGRAAVTDPGGDIDRILSAARQQGARIEKILLT
CCCCCCCEEEEEECCCCCCCCEEEECCCCCEEEECCCCCHHHHHHHHHHCCCCEEEEEEE
HGHVDHCAAADALRTQLGVPIEGPHRDEAFWIDQLPTQSQRFGFPPARAFVPDRWLDDGD
CCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCHHCCCCCHHCCCCCCCCCCCC
TVEAAGRTLEVFHCPGHTPGHVVFFSRPDRIAIVGDVLFAGSIGRTDFPRGNHADLIRSI
EEHHCCCEEEEEECCCCCCCEEEEEECCCEEEEEEEEEEECCCCCCCCCCCCHHHHHHHH
RTKLWPLGDDVTFVPGHGPVSTFGDERATNPYVADRLFADEGTA
HHHHCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]