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The map label for this gene is gltP [H]

Identifier: 17547888

GI number: 17547888

Start: 3428813

End: 3429193

Strand: Reverse

Name: gltP [H]

Synonym: RSc3169

Alternate gene names: 17547888

Gene position: 3429193-3428813 (Counterclockwise)

Preceding gene: 17547893

Following gene: 17547886

Centisome position: 92.27

GC content: 57.74

Gene sequence:

>381_bases
ATGGAAACCACAGTAGATGAGGGGACAGCCGTGCCCGTGGAGAAAAAGGCTCCACGAATCGGCCTGGCATGGCAGATCGC
TATTGGCCTGACCGCAGGGGTGCTGGTTGGCTTCGTGCTGAGTCAGTACCCAGCCTTGCGCGAGTCGGTCATCAGTGACT
ACCTTCAGCCAGCAGGGGACTTGTTCATCAAGTTGATCAAGATGATCGTGGTTCCCATTGTGCTGACAAGCATGATCGTC
GGTATCGCTGGCGTGGGAGACGGGAAATCCCTGGGACGGATTGGTCTTAAGACGCACCCCTTTCAAGGTCTTTCCGCCCG
GGCCTTTTTGAGTACGCGGGCAGTGCAGACATGGGCTCGGGCGATGCTGCCGTCCACATAG

Upstream 100 bases:

>100_bases
GGCAGTTCCGAGGTAACGCACGCCGCTCCGTGATTTCAACGCGGCCAGCGCTTTCAGCTTGATTCCAGACAGCAACGGAA
CAAACAAAAAAAGGAGACGT

Downstream 100 bases:

>100_bases
CCCGTGGGCTTGTCGATCTTGGGGCCGCGTTTGCTCGTGGCCACTTGCGTGGGTGAGATGCGCCGCGCCAAGTGCAACAG
CCTTTGAGCCAGCGACTGCG

Product: transport, fragment transmembrane protein

Products: L-aspartate [Cytoplasm]; Proton [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate-aspartate carrier protein [H]

Number of amino acids: Translated: 126; Mature: 126

Protein sequence:

>126_residues
METTVDEGTAVPVEKKAPRIGLAWQIAIGLTAGVLVGFVLSQYPALRESVISDYLQPAGDLFIKLIKMIVVPIVLTSMIV
GIAGVGDGKSLGRIGLKTHPFQGLSARAFLSTRAVQTWARAMLPST

Sequences:

>Translated_126_residues
METTVDEGTAVPVEKKAPRIGLAWQIAIGLTAGVLVGFVLSQYPALRESVISDYLQPAGDLFIKLIKMIVVPIVLTSMIV
GIAGVGDGKSLGRIGLKTHPFQGLSARAFLSTRAVQTWARAMLPST
>Mature_126_residues
METTVDEGTAVPVEKKAPRIGLAWQIAIGLTAGVLVGFVLSQYPALRESVISDYLQPAGDLFIKLIKMIVVPIVLTSMIV
GIAGVGDGKSLGRIGLKTHPFQGLSARAFLSTRAVQTWARAMLPST

Specific function: This carrier protein is part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system [H]

COG id: COG1301

COG function: function code C; Na+/H+-dicarboxylate symporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI1790514, Length=83, Percent_Identity=53.0120481927711, Blast_Score=91, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991
- InterPro:   IPR018107 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 13361; Mature: 13361

Theoretical pI: Translated: 10.38; Mature: 10.38

Prosite motif: PS00713 NA_DICARBOXYL_SYMP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METTVDEGTAVPVEKKAPRIGLAWQIAIGLTAGVLVGFVLSQYPALRESVISDYLQPAGD
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHH
LFIKLIKMIVVPIVLTSMIVGIAGVGDGKSLGRIGLKTHPFQGLSARAFLSTRAVQTWAR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
AMLPST
HHCCCC
>Mature Secondary Structure
METTVDEGTAVPVEKKAPRIGLAWQIAIGLTAGVLVGFVLSQYPALRESVISDYLQPAGD
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHH
LFIKLIKMIVVPIVLTSMIVGIAGVGDGKSLGRIGLKTHPFQGLSARAFLSTRAVQTWAR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
AMLPST
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate [Periplasm]; Proton [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-aspartate [Periplasm] = Proton [Cytoplasm] + L-aspartate [Cytoplasm] Proton [Periplasm] + L-glutamate [Periplasm] = Proton [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1971622; 1551855; 8265357; 9278503 [H]