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The map label for this gene is aroB [H]

Identifier: 17547688

GI number: 17547688

Start: 3201298

End: 3202404

Strand: Reverse

Name: aroB [H]

Synonym: RSc2969

Alternate gene names: 17547688

Gene position: 3202404-3201298 (Counterclockwise)

Preceding gene: 17547689

Following gene: 17547687

Centisome position: 86.17

GC content: 67.12

Gene sequence:

>1107_bases
ATGATTACCGTTGATGTCGACCTGGGCGAGCGCGCCTATCCGATCCATATCGGAACCGGGCTCCTGTCCCAAGCCGAACT
GTTTGCCCCCCATATCCGCGGCACCCGTGCCGTGATCGTCACCAATGAGACGGTGGCGCCGCTCTATGCCGCTCGGGTCG
AAGCCGCGATCCGCTCGCTGGGCAAGACCGTCGACATGGTGGTGCTGCCCGACGGTGAATCGTTCAAGACGTGGGAGACG
CTCAACCGGATCTTCGATGCACTCCTGGCCTCGGGCGCTGACCGCAAGACCACCCTCGTGGCGCTCGGCGGAGGGGTGAT
CGGCGACATGACCGGATTTGCCGCCGCCAGCTATATGCGCGGCGTGCCGTTCATCCAGGTGCCGACCACGTTGCTGTCCC
AGGTCGATTCGTCGGTGGGGGGCAAGACCGGGATCAATCACCCGCTCGGCAAGAACATGATCGGTGCGTTCCACCAACCG
CAGGCGGTGCTGGCCGACATCGACACGCTGCGCACGCTGCCGCCGCGCGAGCTCGCCGCCGGCATGGCCGAAGTCATCAA
GCATGGCGCGATCGCCGATGCCGACTACTTCGCCTGGATCGAGCGCCACATTGCCGGCCTCAATGCTTGCGATGCCGACC
TGATGGCAGGAGCCGTGCGCGGCTCGGTGCAGATCAAGGCGGCCGTGGTGGCACAGGACGAGCGCGAGTCCGGTCTGCGC
GCCATCCTCAACTTCGGCCACACCTTCGGCCACGCCATCGAAGCGGGCCTGGGGTACGGCGAATGGCTGCACGGCGAGGC
TGTCGGCTGCGGCATGGCGATGGCGGCGGATCTGTCGCACCGGCTCGGGTTCATCGACATCGATACGCGCAACCGCGTGA
CGGCGCTGACACGCGCGGCCAACCTGCCGGTGGTGGCGCCCGATCTGGGCGTGGCGCGCTTCATCGACCTGATGCGCGTC
GACAAGAAGGCCGAGGCGGGCGAGATCAAGTTCGTCCTGCTGCGCAAGCTGGGCCAAGCGTTCGTGACCACGGTACCCGA
CACCGACCTGCGCGCCACGCTGCAGCATGCCGTGCTGCGTCCGCCCACCGAAGCGCCGGTGGCCTGA

Upstream 100 bases:

>100_bases
TGGCCCAGCTTGTTAATATGGTGCTGATGCAACTCGAAGTGGCCGGCATCGTGGTGCCGCCCGCCGCCTCTTCCCCGACC
TCGCAAGTCTCCCGCCAGTC

Downstream 100 bases:

>100_bases
CCGACGGAGTGCCGGCCTGATGAACGATCGACTCGACCTGCTGCCCGCGCCGTTCGATCTGGAAGGCCATCTTGCCCCCT
ATGCCGCACATGCCGCGCAG

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MITVDVDLGERAYPIHIGTGLLSQAELFAPHIRGTRAVIVTNETVAPLYAARVEAAIRSLGKTVDMVVLPDGESFKTWET
LNRIFDALLASGADRKTTLVALGGGVIGDMTGFAAASYMRGVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFHQP
QAVLADIDTLRTLPPRELAAGMAEVIKHGAIADADYFAWIERHIAGLNACDADLMAGAVRGSVQIKAAVVAQDERESGLR
AILNFGHTFGHAIEAGLGYGEWLHGEAVGCGMAMAADLSHRLGFIDIDTRNRVTALTRAANLPVVAPDLGVARFIDLMRV
DKKAEAGEIKFVLLRKLGQAFVTTVPDTDLRATLQHAVLRPPTEAPVA

Sequences:

>Translated_368_residues
MITVDVDLGERAYPIHIGTGLLSQAELFAPHIRGTRAVIVTNETVAPLYAARVEAAIRSLGKTVDMVVLPDGESFKTWET
LNRIFDALLASGADRKTTLVALGGGVIGDMTGFAAASYMRGVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFHQP
QAVLADIDTLRTLPPRELAAGMAEVIKHGAIADADYFAWIERHIAGLNACDADLMAGAVRGSVQIKAAVVAQDERESGLR
AILNFGHTFGHAIEAGLGYGEWLHGEAVGCGMAMAADLSHRLGFIDIDTRNRVTALTRAANLPVVAPDLGVARFIDLMRV
DKKAEAGEIKFVLLRKLGQAFVTTVPDTDLRATLQHAVLRPPTEAPVA
>Mature_368_residues
MITVDVDLGERAYPIHIGTGLLSQAELFAPHIRGTRAVIVTNETVAPLYAARVEAAIRSLGKTVDMVVLPDGESFKTWET
LNRIFDALLASGADRKTTLVALGGGVIGDMTGFAAASYMRGVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFHQP
QAVLADIDTLRTLPPRELAAGMAEVIKHGAIADADYFAWIERHIAGLNACDADLMAGAVRGSVQIKAAVVAQDERESGLR
AILNFGHTFGHAIEAGLGYGEWLHGEAVGCGMAMAADLSHRLGFIDIDTRNRVTALTRAANLPVVAPDLGVARFIDLMRV
DKKAEAGEIKFVLLRKLGQAFVTTVPDTDLRATLQHAVLRPPTEAPVA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=345, Percent_Identity=54.4927536231884, Blast_Score=358, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6320332, Length=396, Percent_Identity=38.8888888888889, Blast_Score=224, Evalue=1e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 39066; Mature: 39066

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITVDVDLGERAYPIHIGTGLLSQAELFAPHIRGTRAVIVTNETVAPLYAARVEAAIRSL
CEEEEECCCCCEEEEEECCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHH
GKTVDMVVLPDGESFKTWETLNRIFDALLASGADRKTTLVALGGGVIGDMTGFAAASYMR
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHC
GVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFHQPQAVLADIDTLRTLPPRELAA
CCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHCCCHHHHHH
GMAEVIKHGAIADADYFAWIERHIAGLNACDADLMAGAVRGSVQIKAAVVAQDERESGLR
HHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEEEEEEECCCHHHHHH
AILNFGHTFGHAIEAGLGYGEWLHGEAVGCGMAMAADLSHRLGFIDIDTRNRVTALTRAA
HHHHHHHHHHHHHHHCCCCCCHHCCCHHHCHHHHHHHHHHCCCEEEECCCCHHHHHHHHC
NLPVVAPDLGVARFIDLMRVDKKAEAGEIKFVLLRKLGQAFVTTVPDTDLRATLQHAVLR
CCCEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHEECCCCCHHHHHHHHHHCC
PPTEAPVA
CCCCCCCC
>Mature Secondary Structure
MITVDVDLGERAYPIHIGTGLLSQAELFAPHIRGTRAVIVTNETVAPLYAARVEAAIRSL
CEEEEECCCCCEEEEEECCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHH
GKTVDMVVLPDGESFKTWETLNRIFDALLASGADRKTTLVALGGGVIGDMTGFAAASYMR
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHC
GVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFHQPQAVLADIDTLRTLPPRELAA
CCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHCCCHHHHHH
GMAEVIKHGAIADADYFAWIERHIAGLNACDADLMAGAVRGSVQIKAAVVAQDERESGLR
HHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEEEEEEECCCHHHHHH
AILNFGHTFGHAIEAGLGYGEWLHGEAVGCGMAMAADLSHRLGFIDIDTRNRVTALTRAA
HHHHHHHHHHHHHHHCCCCCCHHCCCHHHCHHHHHHHHHHCCCEEEECCCCHHHHHHHHC
NLPVVAPDLGVARFIDLMRVDKKAEAGEIKFVLLRKLGQAFVTTVPDTDLRATLQHAVLR
CCCEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHEECCCCCHHHHHHHHHHCC
PPTEAPVA
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA