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The map label for this gene is ggt2 [H]

Identifier: 17547640

GI number: 17547640

Start: 3149308

End: 3151179

Strand: Reverse

Name: ggt2 [H]

Synonym: RSc2921

Alternate gene names: 17547640

Gene position: 3151179-3149308 (Counterclockwise)

Preceding gene: 17547642

Following gene: 17547636

Centisome position: 84.79

GC content: 73.18

Gene sequence:

>1872_bases
ATGGCAACCCAGGCTGTTTCCTTGGCGCGCGTGCGCGGCCCGCTGGCGCTGGCGGCGCTGACGCTGCTCGGCGCATGTTC
CACGCGGACCGCCGTGCCGACGCCGGCCCCAGTGGCCGGCTCGCCGTCTGTCGCGCCCGAGTCGCCGCGCCCGCCGGAGG
TGGCCTCGGGCTACCGCACCGGCATGACGACGGCCTACGCCGAGCAGCACATGGCCGCCGCCGCCAACCCGCTCGCGGCG
GAAGCGGGCCGGCGCATCCTGCGGCAGGGCGGCTCGGCCATCGACGCGGCCATCGCCATGCAGGCCGTGCTGACGCTGGT
CGAGCCGCAGGCCTCCGGTATCGGCGGTGGCGCCTTCCTCCTCTACTGGGACGGCAAGCGCGTGCAGGCCTATGACGGCT
GGGAGACCGCCCCGGCCGGTGCCGACGAGAACCTGTTCCTGCGCCCCGACGGCACGTCGATGGGCTTGAGCGAGGCCCGG
ATCGGCGGCCGCGCGGTCGGCGTGCCCGGCGTGCTGCGCGCGCTGGAGCTGGCCCACCGCCGGTACGGCAAGCTGCCCTG
GACCAGACTGCTCCAGCCGGCCGTCGAGCTGGCGGAGCAGGGGTTCCCGGTTTCGCCGCGGCTCTATACGCAGATCGCGG
CCGACCCGTTCATCGCCGGGTCGCCGGAGATGGCGGCGTATTTCCTCACGCCGCAAGGCAAGCCCAAGCCGGTCGGGACG
ATCGTGAGGAACCCGCAGCTGGCGCAGACGCTGCGCGAGATCGCCAGGCACGGCCCCGGCGCGTTCTATGCCGGGCCGAT
CGCGGCCGACATCGTCAAACGCGTGAGCGGCGGCGCCAATCCGGGCACGCTGTCGCTGGCTGACCTGCGGGGCTATCGCG
CCAAAGAGCGCGATCCCATCTGCGCCGACTACCAGCGCTGGAAGGTCTGCGGCATGCCCCCGCCGTCGTCGGGCGGCATC
GCCATCGCGCAGATGCTGGGCACGCTGCAGGCCCTGGCGGCGCGCGATCCGAAGTACGCGCTGGCCGCGATGGCACCGCG
CGAGACCACCCGCGCCGCCGGCCTCGAACCCAGCGTCGACGCCGTGCACGTGGTGTCCGAAGCCGGGCGCCAGGCCGATG
CGGATCGCGGCCTTTACGTGGCCGACGCGGATTTCGTGCCGGTCAACGTCAAGGGCCTGACCGATCCGGGGTACCTGACG
CTGCGCGCCGGGCTGATCGGCGACCGGAGCACGGGCCGGGCCGATCCCGGCACGCCGCCCGGGACCTCCATCGCGCTGGC
GCCGGACCGCTCGCCGCCGCGCGTATCGACCTCGCAGATCGTGGCGGTGGACAACGCCGGCGGCGCGGTGTCCATGACGA
CCGCCATCGACAGCGATTTCGGCGCGCACCTGATGGTGCGCGGCTTCGTGCTGAACAGCGGGCTCACCGATTTCTCGTTC
GTGCCGAACGACGGCGGCAAGCCGGTCGCCAATCGCGTGCAGGCCGGCAAGCGGCCGCGCTCGTCGATGGCGCCGACGCT
GGTGTTCGAACGCGACAGCGGCCGGCTGGTGGCGGCGCTCGGTTCGCCCGGCGGCTCGCAGAGTATCGAATACGTGTCGA
AGACGCTGATCGGTCTGCTGGACTGGGACATGGACGTGCAGAGTGCGATCAACCTGCCCAACTTCGGCAGCCGCAACGGC
CCGACCGAGGTGGAGCGGGGTCTGGTGACGCAGCCGCTGGTACAGGGCCTGAAGGCGCGCGGCCACGACGTCGCGCAGAT
CGAGATGACCAGCGGCACGCAGGCCATCGTGCGGCGCCGGCGCGACGACGGCAGGTGGGGCTGGGCCGGCGGCGCCGACC
CGCGCCGCGAAGGGGTGGCGCTGGGCGACTGA

Upstream 100 bases:

>100_bases
TGGGTCCGGCATGGTGTACCGGGCGGTGGGTTTGGGGCAGGGCCCGGCACGTCACCATCCGCTTCCTGCAATGAGGCTTT
GGAATCACGAGGAGAACCGC

Downstream 100 bases:

>100_bases
GCCGCGCGCCTGCATCGGGCCGGGCGGACGGGCCGTGCACTGCGCACGGCCCGTCTGCTTTTGCGGCAGCGACGCTACCA
GGCGTATTTCGCGGTCGCGA

Product: gamma-glutamyltranspeptidase precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 623; Mature: 622

Protein sequence:

>623_residues
MATQAVSLARVRGPLALAALTLLGACSTRTAVPTPAPVAGSPSVAPESPRPPEVASGYRTGMTTAYAEQHMAAAANPLAA
EAGRRILRQGGSAIDAAIAMQAVLTLVEPQASGIGGGAFLLYWDGKRVQAYDGWETAPAGADENLFLRPDGTSMGLSEAR
IGGRAVGVPGVLRALELAHRRYGKLPWTRLLQPAVELAEQGFPVSPRLYTQIAADPFIAGSPEMAAYFLTPQGKPKPVGT
IVRNPQLAQTLREIARHGPGAFYAGPIAADIVKRVSGGANPGTLSLADLRGYRAKERDPICADYQRWKVCGMPPPSSGGI
AIAQMLGTLQALAARDPKYALAAMAPRETTRAAGLEPSVDAVHVVSEAGRQADADRGLYVADADFVPVNVKGLTDPGYLT
LRAGLIGDRSTGRADPGTPPGTSIALAPDRSPPRVSTSQIVAVDNAGGAVSMTTAIDSDFGAHLMVRGFVLNSGLTDFSF
VPNDGGKPVANRVQAGKRPRSSMAPTLVFERDSGRLVAALGSPGGSQSIEYVSKTLIGLLDWDMDVQSAINLPNFGSRNG
PTEVERGLVTQPLVQGLKARGHDVAQIEMTSGTQAIVRRRRDDGRWGWAGGADPRREGVALGD

Sequences:

>Translated_623_residues
MATQAVSLARVRGPLALAALTLLGACSTRTAVPTPAPVAGSPSVAPESPRPPEVASGYRTGMTTAYAEQHMAAAANPLAA
EAGRRILRQGGSAIDAAIAMQAVLTLVEPQASGIGGGAFLLYWDGKRVQAYDGWETAPAGADENLFLRPDGTSMGLSEAR
IGGRAVGVPGVLRALELAHRRYGKLPWTRLLQPAVELAEQGFPVSPRLYTQIAADPFIAGSPEMAAYFLTPQGKPKPVGT
IVRNPQLAQTLREIARHGPGAFYAGPIAADIVKRVSGGANPGTLSLADLRGYRAKERDPICADYQRWKVCGMPPPSSGGI
AIAQMLGTLQALAARDPKYALAAMAPRETTRAAGLEPSVDAVHVVSEAGRQADADRGLYVADADFVPVNVKGLTDPGYLT
LRAGLIGDRSTGRADPGTPPGTSIALAPDRSPPRVSTSQIVAVDNAGGAVSMTTAIDSDFGAHLMVRGFVLNSGLTDFSF
VPNDGGKPVANRVQAGKRPRSSMAPTLVFERDSGRLVAALGSPGGSQSIEYVSKTLIGLLDWDMDVQSAINLPNFGSRNG
PTEVERGLVTQPLVQGLKARGHDVAQIEMTSGTQAIVRRRRDDGRWGWAGGADPRREGVALGD
>Mature_622_residues
ATQAVSLARVRGPLALAALTLLGACSTRTAVPTPAPVAGSPSVAPESPRPPEVASGYRTGMTTAYAEQHMAAAANPLAAE
AGRRILRQGGSAIDAAIAMQAVLTLVEPQASGIGGGAFLLYWDGKRVQAYDGWETAPAGADENLFLRPDGTSMGLSEARI
GGRAVGVPGVLRALELAHRRYGKLPWTRLLQPAVELAEQGFPVSPRLYTQIAADPFIAGSPEMAAYFLTPQGKPKPVGTI
VRNPQLAQTLREIARHGPGAFYAGPIAADIVKRVSGGANPGTLSLADLRGYRAKERDPICADYQRWKVCGMPPPSSGGIA
IAQMLGTLQALAARDPKYALAAMAPRETTRAAGLEPSVDAVHVVSEAGRQADADRGLYVADADFVPVNVKGLTDPGYLTL
RAGLIGDRSTGRADPGTPPGTSIALAPDRSPPRVSTSQIVAVDNAGGAVSMTTAIDSDFGAHLMVRGFVLNSGLTDFSFV
PNDGGKPVANRVQAGKRPRSSMAPTLVFERDSGRLVAALGSPGGSQSIEYVSKTLIGLLDWDMDVQSAINLPNFGSRNGP
TEVERGLVTQPLVQGLKARGHDVAQIEMTSGTQAIVRRRRDDGRWGWAGGADPRREGVALGD

Specific function: GGT PLAYS A KEY ROLE IN THE GAMMA-GLUTAMYL CYCLE, A PATHWAY FOR THE SYNTHESIS AND DEGRADATION OF GLUTATHIONE. [C]

COG id: COG0405

COG function: function code E; Gamma-glutamyltransferase

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-glutamyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI73915092, Length=555, Percent_Identity=31.5315315315315, Blast_Score=185, Evalue=1e-46,
Organism=Homo sapiens, GI73915090, Length=555, Percent_Identity=31.5315315315315, Blast_Score=185, Evalue=1e-46,
Organism=Homo sapiens, GI73915096, Length=555, Percent_Identity=31.5315315315315, Blast_Score=185, Evalue=1e-46,
Organism=Homo sapiens, GI73915094, Length=555, Percent_Identity=31.5315315315315, Blast_Score=185, Evalue=1e-46,
Organism=Homo sapiens, GI113429324, Length=567, Percent_Identity=30.6878306878307, Blast_Score=174, Evalue=3e-43,
Organism=Homo sapiens, GI113429326, Length=574, Percent_Identity=30.8362369337979, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI109148539, Length=526, Percent_Identity=27.7566539923954, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI153266885, Length=541, Percent_Identity=28.2809611829945, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI153266901, Length=542, Percent_Identity=27.6752767527675, Blast_Score=122, Evalue=8e-28,
Organism=Homo sapiens, GI153266907, Length=539, Percent_Identity=26.9016697588126, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI30581157, Length=192, Percent_Identity=34.375, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI30581155, Length=192, Percent_Identity=34.375, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI171543825, Length=176, Percent_Identity=30.1136363636364, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1789856, Length=551, Percent_Identity=34.8457350272232, Blast_Score=246, Evalue=3e-66,
Organism=Caenorhabditis elegans, GI17542894, Length=566, Percent_Identity=31.8021201413428, Blast_Score=216, Evalue=3e-56,
Organism=Caenorhabditis elegans, GI212646519, Length=520, Percent_Identity=30.5769230769231, Blast_Score=185, Evalue=7e-47,
Organism=Caenorhabditis elegans, GI72000294, Length=520, Percent_Identity=30.5769230769231, Blast_Score=184, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI193208247, Length=536, Percent_Identity=28.7313432835821, Blast_Score=163, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI193208245, Length=536, Percent_Identity=28.7313432835821, Blast_Score=162, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI17506189, Length=533, Percent_Identity=29.4559099437148, Blast_Score=157, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17564448, Length=457, Percent_Identity=24.945295404814, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI72001497, Length=276, Percent_Identity=26.0869565217391, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI72001495, Length=276, Percent_Identity=26.0869565217391, Blast_Score=80, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6323330, Length=536, Percent_Identity=23.8805970149254, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI45551474, Length=571, Percent_Identity=29.2469352014011, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24642670, Length=571, Percent_Identity=29.2469352014011, Blast_Score=186, Evalue=3e-47,
Organism=Drosophila melanogaster, GI24642666, Length=571, Percent_Identity=29.2469352014011, Blast_Score=186, Evalue=3e-47,
Organism=Drosophila melanogaster, GI161077878, Length=572, Percent_Identity=29.5454545454545, Blast_Score=186, Evalue=3e-47,
Organism=Drosophila melanogaster, GI161077880, Length=572, Percent_Identity=29.5454545454545, Blast_Score=186, Evalue=4e-47,
Organism=Drosophila melanogaster, GI18859893, Length=533, Percent_Identity=28.1425891181989, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI161077496, Length=535, Percent_Identity=27.6635514018692, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI18859741, Length=529, Percent_Identity=26.4650283553875, Blast_Score=132, Evalue=9e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000101 [H]

Pfam domain/function: PF01019 G_glu_transpept [H]

EC number: =2.3.2.2 [H]

Molecular weight: Translated: 65011; Mature: 64879

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATQAVSLARVRGPLALAALTLLGACSTRTAVPTPAPVAGSPSVAPESPRPPEVASGYRT
CCCCHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCHHC
GMTTAYAEQHMAAAANPLAAEAGRRILRQGGSAIDAAIAMQAVLTLVEPQASGIGGGAFL
CCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEE
LYWDGKRVQAYDGWETAPAGADENLFLRPDGTSMGLSEARIGGRAVGVPGVLRALELAHR
EEECCCEEEECCCCCCCCCCCCCCEEECCCCCCCCCHHHHCCCEEECHHHHHHHHHHHHH
RYGKLPWTRLLQPAVELAEQGFPVSPRLYTQIAADPFIAGSPEMAAYFLTPQGKPKPVGT
HHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCHH
IVRNPQLAQTLREIARHGPGAFYAGPIAADIVKRVSGGANPGTLSLADLRGYRAKERDPI
HHCCCHHHHHHHHHHHCCCCCEECCHHHHHHHHHHCCCCCCCEEEHHHHCCCCCCCCCCC
CADYQRWKVCGMPPPSSGGIAIAQMLGTLQALAARDPKYALAAMAPRETTRAAGLEPSVD
CCCCHHCEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHCCCCCCCH
AVHVVSEAGRQADADRGLYVADADFVPVNVKGLTDPGYLTLRAGLIGDRSTGRADPGTPP
HHHHHHHHCCCCCCCCCEEEECCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCC
GTSIALAPDRSPPRVSTSQIVAVDNAGGAVSMTTAIDSDFGAHLMVRGFVLNSGLTDFSF
CCEEEECCCCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCEEEEEEEEECCCCCCCEE
VPNDGGKPVANRVQAGKRPRSSMAPTLVFERDSGRLVAALGSPGGSQSIEYVSKTLIGLL
CCCCCCCHHHHHHHCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHH
DWDMDVQSAINLPNFGSRNGPTEVERGLVTQPLVQGLKARGHDVAQIEMTSGTQAIVRRR
CCCCCHHHHCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHH
RDDGRWGWAGGADPRREGVALGD
CCCCCCCCCCCCCHHHCCCCCCC
>Mature Secondary Structure 
ATQAVSLARVRGPLALAALTLLGACSTRTAVPTPAPVAGSPSVAPESPRPPEVASGYRT
CCCHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCHHC
GMTTAYAEQHMAAAANPLAAEAGRRILRQGGSAIDAAIAMQAVLTLVEPQASGIGGGAFL
CCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEE
LYWDGKRVQAYDGWETAPAGADENLFLRPDGTSMGLSEARIGGRAVGVPGVLRALELAHR
EEECCCEEEECCCCCCCCCCCCCCEEECCCCCCCCCHHHHCCCEEECHHHHHHHHHHHHH
RYGKLPWTRLLQPAVELAEQGFPVSPRLYTQIAADPFIAGSPEMAAYFLTPQGKPKPVGT
HHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCHH
IVRNPQLAQTLREIARHGPGAFYAGPIAADIVKRVSGGANPGTLSLADLRGYRAKERDPI
HHCCCHHHHHHHHHHHCCCCCEECCHHHHHHHHHHCCCCCCCEEEHHHHCCCCCCCCCCC
CADYQRWKVCGMPPPSSGGIAIAQMLGTLQALAARDPKYALAAMAPRETTRAAGLEPSVD
CCCCHHCEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHCCCCCCCH
AVHVVSEAGRQADADRGLYVADADFVPVNVKGLTDPGYLTLRAGLIGDRSTGRADPGTPP
HHHHHHHHCCCCCCCCCEEEECCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCC
GTSIALAPDRSPPRVSTSQIVAVDNAGGAVSMTTAIDSDFGAHLMVRGFVLNSGLTDFSF
CCEEEECCCCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCEEEEEEEEECCCCCCCEE
VPNDGGKPVANRVQAGKRPRSSMAPTLVFERDSGRLVAALGSPGGSQSIEYVSKTLIGLL
CCCCCCCHHHHHHHCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHH
DWDMDVQSAINLPNFGSRNGPTEVERGLVTQPLVQGLKARGHDVAQIEMTSGTQAIVRRR
CCCCCHHHHCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHH
RDDGRWGWAGGADPRREGVALGD
CCCCCCCCCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA