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The map label for this gene is paaK [H]

Identifier: 17547594

GI number: 17547594

Start: 3103810

End: 3105120

Strand: Direct

Name: paaK [H]

Synonym: RSc2875

Alternate gene names: 17547594

Gene position: 3103810-3105120 (Clockwise)

Preceding gene: 17547593

Following gene: 17547596

Centisome position: 83.52

GC content: 69.79

Gene sequence:

>1311_bases
ATGCGCCCCCGCTTGACCGACCTGCCGCTCGATCCGATCGAAACCGCCAGCCGCGATGCCGTCCAGGCGCTGCAGCTGGA
GCGGCTCCGGCACAGCCTTGCCCATGCGTACGCGAACGTGCCGGCGTACCGCGCCAAGTTCGATGCGGTGGGCGTGCATC
CGTCGGACCTGCGCGCGCTTGGCGACCTGGCGAGATTTCCGTTCACCACCAAGGCGGATCTGCGGGAGAACTATCCGTTC
GGCATGTTCGCCGTGCCGCAGGAGCGCATCGCGCGCATCCATGCGTCGTCGGGAACGACCGGCAAGCCGACGGTGGTGGG
CTATACGCTGGCCGATATCGACACCTGGGCAGGGCTGGTGGCGCGCTCGATCCGCGCGGCGGGGGCGCGGCGCGGCGACA
AGGTTCACGTCAGCTACGGCTACGGGCTCTTCACCGGCGGCCTGGGCGCGCATTACGGCGCGGAGCGCGCGGGGCTGACG
GTGATTCCGTTCGGCGGCGGGCAGACGGAGCGGCAGGTGCAGCTGATCCGCGATTTCCAGCCGCAGATCATCATGGTGAC
GCCCAGCTACATGCTGGCCATCGCCGACGAATTCGTACGCCAGGGGCTGGACCCGGCCCAGTCCAGCCTGCGAATCGGCA
TCTTCGGCGCGGAGCCGTGGACGCCCGAGATGCGCACGGTGATCGAGGCTCGCATGGGGCTGTCGGCGGTGGACATCTAC
GGCCTGTCGGAGGTGATGGGCCCGGGCGTGGCCAGCGAATGCGCCGAGACCAAGGACGGCCCGACGATCTGGGAAGACCA
CTTCTACCCGGAGATCATCGACCCGGAAACCGGCACCGTGCTGCCCGACGGCGCGTTCGGCGAGCTGGTCTTCACGTCGC
TCACCAAGGAGGCGATGCCGGTGGTCCGCTACCGCACGCGCGACCTGACGCGCCTGCTGCCGGGCACGGCGCGGCCGGCT
TTCCGCCGCATGGAGAAGATCACGGGCCGCTGCGACGACATGATGATCGTGCGGGGCGTGAATGTGTTCCCGTCGCAGAT
CGAGGAACTGATCCTGAAGCACGCGGCGCTGTCGCCGCACTACCAGTGCGTGCTGGCCAAGGAAGGCCCGCTCGATACGC
TGACGGTGCGGGTGGAGGCGGCGCTCGGGACGCCGGCCGAGGTGGCGGACGCAGCCGGCGGACAGCTGGCGCACGACATC
AAGGCGATGATCGGCGTGACTGCGGCGATCGAGCTGCTGGCCGTCGGCGGGGTCGAGCGCTCGGTCGGGAAGGCGCGCCG
CGTGGTGGATCTGCGGCGCGGCCAGCCGTAG

Upstream 100 bases:

>100_bases
ACGTCATCCCCGTTCCGGACAGCGGCGACCGCTGATCCCCTCCTATATATAGAGAGTTGCCACGACATGGGCCCGCCCGA
TGGTGCCCAAGGAGACCTGC

Downstream 100 bases:

>100_bases
CCGCTAGCGCGAGGCCACGCCGACGGGGCTGCCCTTCGGCACCAGCACCCACAGCCGGCCGGCCTGCTTCATGCGGCCGG
CCAGGTCGCCTGCCGCGTCG

Product: phenylacetyl-CoA-ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MRPRLTDLPLDPIETASRDAVQALQLERLRHSLAHAYANVPAYRAKFDAVGVHPSDLRALGDLARFPFTTKADLRENYPF
GMFAVPQERIARIHASSGTTGKPTVVGYTLADIDTWAGLVARSIRAAGARRGDKVHVSYGYGLFTGGLGAHYGAERAGLT
VIPFGGGQTERQVQLIRDFQPQIIMVTPSYMLAIADEFVRQGLDPAQSSLRIGIFGAEPWTPEMRTVIEARMGLSAVDIY
GLSEVMGPGVASECAETKDGPTIWEDHFYPEIIDPETGTVLPDGAFGELVFTSLTKEAMPVVRYRTRDLTRLLPGTARPA
FRRMEKITGRCDDMMIVRGVNVFPSQIEELILKHAALSPHYQCVLAKEGPLDTLTVRVEAALGTPAEVADAAGGQLAHDI
KAMIGVTAAIELLAVGGVERSVGKARRVVDLRRGQP

Sequences:

>Translated_436_residues
MRPRLTDLPLDPIETASRDAVQALQLERLRHSLAHAYANVPAYRAKFDAVGVHPSDLRALGDLARFPFTTKADLRENYPF
GMFAVPQERIARIHASSGTTGKPTVVGYTLADIDTWAGLVARSIRAAGARRGDKVHVSYGYGLFTGGLGAHYGAERAGLT
VIPFGGGQTERQVQLIRDFQPQIIMVTPSYMLAIADEFVRQGLDPAQSSLRIGIFGAEPWTPEMRTVIEARMGLSAVDIY
GLSEVMGPGVASECAETKDGPTIWEDHFYPEIIDPETGTVLPDGAFGELVFTSLTKEAMPVVRYRTRDLTRLLPGTARPA
FRRMEKITGRCDDMMIVRGVNVFPSQIEELILKHAALSPHYQCVLAKEGPLDTLTVRVEAALGTPAEVADAAGGQLAHDI
KAMIGVTAAIELLAVGGVERSVGKARRVVDLRRGQP
>Mature_436_residues
MRPRLTDLPLDPIETASRDAVQALQLERLRHSLAHAYANVPAYRAKFDAVGVHPSDLRALGDLARFPFTTKADLRENYPF
GMFAVPQERIARIHASSGTTGKPTVVGYTLADIDTWAGLVARSIRAAGARRGDKVHVSYGYGLFTGGLGAHYGAERAGLT
VIPFGGGQTERQVQLIRDFQPQIIMVTPSYMLAIADEFVRQGLDPAQSSLRIGIFGAEPWTPEMRTVIEARMGLSAVDIY
GLSEVMGPGVASECAETKDGPTIWEDHFYPEIIDPETGTVLPDGAFGELVFTSLTKEAMPVVRYRTRDLTRLLPGTARPA
FRRMEKITGRCDDMMIVRGVNVFPSQIEELILKHAALSPHYQCVLAKEGPLDTLTVRVEAALGTPAEVADAAGGQLAHDI
KAMIGVTAAIELLAVGGVERSVGKARRVVDLRRGQP

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=433, Percent_Identity=64.6651270207852, Blast_Score=575, Evalue=1e-165,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 47309; Mature: 47309

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPRLTDLPLDPIETASRDAVQALQLERLRHSLAHAYANVPAYRAKFDAVGVHPSDLRAL
CCCCCCCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHH
GDLARFPFTTKADLRENYPFGMFAVPQERIARIHASSGTTGKPTVVGYTLADIDTWAGLV
HHHHHCCCCCCHHHHCCCCCCEEECCHHHHHEEECCCCCCCCCEEEEEEHHHHHHHHHHH
ARSIRAAGARRGDKVHVSYGYGLFTGGLGAHYGAERAGLTVIPFGGGQTERQVQLIRDFQ
HHHHHHHCCCCCCEEEEEECCCEEECCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCC
PQIIMVTPSYMLAIADEFVRQGLDPAQSSLRIGIFGAEPWTPEMRTVIEARMGLSAVDIY
CCEEEECCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCHHHHH
GLSEVMGPGVASECAETKDGPTIWEDHFYPEIIDPETGTVLPDGAFGELVFTSLTKEAMP
CHHHHHCCCHHHHHHCCCCCCCEECCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHH
VVRYRTRDLTRLLPGTARPAFRRMEKITGRCDDMMIVRGVNVFPSQIEELILKHAALSPH
HHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCC
YQCVLAKEGPLDTLTVRVEAALGTPAEVADAAGGQLAHDIKAMIGVTAAIELLAVGGVER
EEEEEECCCCCCEEEEEEEECCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHH
SVGKARRVVDLRRGQP
HHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRPRLTDLPLDPIETASRDAVQALQLERLRHSLAHAYANVPAYRAKFDAVGVHPSDLRAL
CCCCCCCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHH
GDLARFPFTTKADLRENYPFGMFAVPQERIARIHASSGTTGKPTVVGYTLADIDTWAGLV
HHHHHCCCCCCHHHHCCCCCCEEECCHHHHHEEECCCCCCCCCEEEEEEHHHHHHHHHHH
ARSIRAAGARRGDKVHVSYGYGLFTGGLGAHYGAERAGLTVIPFGGGQTERQVQLIRDFQ
HHHHHHHCCCCCCEEEEEECCCEEECCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCC
PQIIMVTPSYMLAIADEFVRQGLDPAQSSLRIGIFGAEPWTPEMRTVIEARMGLSAVDIY
CCEEEECCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCHHHHH
GLSEVMGPGVASECAETKDGPTIWEDHFYPEIIDPETGTVLPDGAFGELVFTSLTKEAMP
CHHHHHCCCHHHHHHCCCCCCCEECCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHH
VVRYRTRDLTRLLPGTARPAFRRMEKITGRCDDMMIVRGVNVFPSQIEELILKHAALSPH
HHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCC
YQCVLAKEGPLDTLTVRVEAALGTPAEVADAAGGQLAHDIKAMIGVTAAIELLAVGGVER
EEEEEECCCCCCEEEEEEEECCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHH
SVGKARRVVDLRRGQP
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]