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The map label for this gene is dppA1 [H]

Identifier: 17547589

GI number: 17547589

Start: 3092348

End: 3093877

Strand: Reverse

Name: dppA1 [H]

Synonym: RSc2870

Alternate gene names: 17547589

Gene position: 3093877-3092348 (Counterclockwise)

Preceding gene: 17547591

Following gene: 17547588

Centisome position: 83.25

GC content: 63.07

Gene sequence:

>1530_bases
ATGGCGGGCATCAGCCCCCAGGCGCTGGCCACCGATTTGAAGATTGGCATGAGTTCGCCGCCGACCTCGATGGACCCGCA
CTTCTACAACCTGTTCTCCAACATCAACGTATCGGAGCACATGTTCGAGTGCTTGGTGAAGATGGATGCGGACAGCCATA
TCGTTCCGGGGCTGGCCGAGTCGTGGAAGATGGTCAACAACCTGACCTGGGAGTTCAAGCTACGGCCGGGCGTGAAGTTC
CATGATGGCAGCGAGCTGACGACGGAGGATGTGGCGTGGTCGCTCGACAGGCCGGCGACCATCGTCAACAGTCCGGGCAA
GTTCGATACCTACACCAAGGCGATCATCCACAAGAAGATCATCGACAAGTACACGATCCAGCTGACGACCTCGCAGCCGT
ATCCGCTGATGCTGTCGGACCTGACCTCGGTGTTCATCGTGCAGAAGAAGGCGACGCAGGGACTGTCGAGCGATGACTTC
GCGCAGGGCAAGGGCATGGTCGGCACCGGGCCGTTCAAGTTCGTCAGCTACGCGCGGGACGACCGTGTCGAGCTGGTGCG
CAACGACCAGTACTGGGGCCCGAAACCGGCTTGGGACAAGGTGACGCTGCGCTTCATTCCCAACGGCGCGACGCGCATCG
CGGCGCTGCTGTCGGGGGACGTGCAGGCGATCGAGAACGTGCCGACGCCGGACCTGGCGCGCGTGCGCGGGGATGCATCG
CTGAATTTTTTCTCGAAGATCTCGCACCGCGTCATCTATCTGTATACGGACGACAAGCGTGACCCGACGCCGGATGTGAC
GGGTAAGGACGGCAAGCCGCTCGCCAAGAATCCGCTCAAGGACCCGCGCGTGCGTCGCGCGATGAGCATGACGATCAACC
GCCAGGGCATCAAGGACCGCATCATGGAGGGCCTGGCGGAGCCGACCGACAACCTGGTGCCACCGCAGCTGTTCGGCTAT
AACCCGAACCTGAAGACCCTCAAGTACGATCCGGAGGGCGCGAAGAAACTGCTGGCCGAGGCGGGCTATCCGGACGGCTT
CGGCATCACGCTGCACACGCCCAACAACCGGTACGTGAACGACGAGAAGATCGCGCAGACCATCGCGCAGAACCTGACGC
GCATCGGCATCGTGACCAAGGTGGAGGGCATGCCGATGGCGACCTTCGCGGCCAAGAGCATCCGGCACGAGTATTCGTTC
GGGCTGGTGGGCTGGGGCGCGCAGACGGGCGAGGTCAGCTCGCCGCTGCGGGCGCTGGTGGCGTGCGAGGATGCCAGGAA
GGGCTACGGTACGGTCAACTGGGGCCAGTACTGCAACCCTAAGATGGACGCGGTGCTCGACAAGGCGCTCTACACCATGG
ACGACAAGGAGCGCTCCAGGCTGCTGCAGGAAGCGACCGCGATCGTGGTCGATGACGGCGGTATCATCCCGGTCCATTTC
CAGGTGACGACGTGGGCGGCGCGCAAGGGCTTCACCTATACGCCGCGCACCGACGAACGCACTTACGCGCAGGGCTTCAT
GCCGCAGTAA

Upstream 100 bases:

>100_bases
GAGATCGAGCCATCGATTCCTTTTCTTGGGGAGAAGAGCCGTGACCATGACTCGGATCTTGCGGCGCGTCGCTGCTGCGA
TGTGTGTGGCGGGGTGTGCG

Downstream 100 bases:

>100_bases
TGTCGTCGTCGCTTCCATTCACACGTAACCGGGCGAGTCTCCGATGCTGGTGTTCCTGATTCGACGGCTGCTGGAATCGG
TGGCGGTGTTGCTGGTGATG

Product: periplasmic dipeptide transport protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 509; Mature: 508

Protein sequence:

>509_residues
MAGISPQALATDLKIGMSSPPTSMDPHFYNLFSNINVSEHMFECLVKMDADSHIVPGLAESWKMVNNLTWEFKLRPGVKF
HDGSELTTEDVAWSLDRPATIVNSPGKFDTYTKAIIHKKIIDKYTIQLTTSQPYPLMLSDLTSVFIVQKKATQGLSSDDF
AQGKGMVGTGPFKFVSYARDDRVELVRNDQYWGPKPAWDKVTLRFIPNGATRIAALLSGDVQAIENVPTPDLARVRGDAS
LNFFSKISHRVIYLYTDDKRDPTPDVTGKDGKPLAKNPLKDPRVRRAMSMTINRQGIKDRIMEGLAEPTDNLVPPQLFGY
NPNLKTLKYDPEGAKKLLAEAGYPDGFGITLHTPNNRYVNDEKIAQTIAQNLTRIGIVTKVEGMPMATFAAKSIRHEYSF
GLVGWGAQTGEVSSPLRALVACEDARKGYGTVNWGQYCNPKMDAVLDKALYTMDDKERSRLLQEATAIVVDDGGIIPVHF
QVTTWAARKGFTYTPRTDERTYAQGFMPQ

Sequences:

>Translated_509_residues
MAGISPQALATDLKIGMSSPPTSMDPHFYNLFSNINVSEHMFECLVKMDADSHIVPGLAESWKMVNNLTWEFKLRPGVKF
HDGSELTTEDVAWSLDRPATIVNSPGKFDTYTKAIIHKKIIDKYTIQLTTSQPYPLMLSDLTSVFIVQKKATQGLSSDDF
AQGKGMVGTGPFKFVSYARDDRVELVRNDQYWGPKPAWDKVTLRFIPNGATRIAALLSGDVQAIENVPTPDLARVRGDAS
LNFFSKISHRVIYLYTDDKRDPTPDVTGKDGKPLAKNPLKDPRVRRAMSMTINRQGIKDRIMEGLAEPTDNLVPPQLFGY
NPNLKTLKYDPEGAKKLLAEAGYPDGFGITLHTPNNRYVNDEKIAQTIAQNLTRIGIVTKVEGMPMATFAAKSIRHEYSF
GLVGWGAQTGEVSSPLRALVACEDARKGYGTVNWGQYCNPKMDAVLDKALYTMDDKERSRLLQEATAIVVDDGGIIPVHF
QVTTWAARKGFTYTPRTDERTYAQGFMPQ
>Mature_508_residues
AGISPQALATDLKIGMSSPPTSMDPHFYNLFSNINVSEHMFECLVKMDADSHIVPGLAESWKMVNNLTWEFKLRPGVKFH
DGSELTTEDVAWSLDRPATIVNSPGKFDTYTKAIIHKKIIDKYTIQLTTSQPYPLMLSDLTSVFIVQKKATQGLSSDDFA
QGKGMVGTGPFKFVSYARDDRVELVRNDQYWGPKPAWDKVTLRFIPNGATRIAALLSGDVQAIENVPTPDLARVRGDASL
NFFSKISHRVIYLYTDDKRDPTPDVTGKDGKPLAKNPLKDPRVRRAMSMTINRQGIKDRIMEGLAEPTDNLVPPQLFGYN
PNLKTLKYDPEGAKKLLAEAGYPDGFGITLHTPNNRYVNDEKIAQTIAQNLTRIGIVTKVEGMPMATFAAKSIRHEYSFG
LVGWGAQTGEVSSPLRALVACEDARKGYGTVNWGQYCNPKMDAVLDKALYTMDDKERSRLLQEATAIVVDDGGIIPVHFQ
VTTWAARKGFTYTPRTDERTYAQGFMPQ

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=494, Percent_Identity=26.1133603238866, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI1787052, Length=501, Percent_Identity=28.3433133732535, Blast_Score=172, Evalue=4e-44,
Organism=Escherichia coli, GI1787762, Length=501, Percent_Identity=25.9481037924152, Blast_Score=145, Evalue=8e-36,
Organism=Escherichia coli, GI1787551, Length=487, Percent_Identity=23.2032854209446, Blast_Score=125, Evalue=8e-30,
Organism=Escherichia coli, GI1787495, Length=521, Percent_Identity=25.1439539347409, Blast_Score=125, Evalue=9e-30,
Organism=Escherichia coli, GI1789887, Length=473, Percent_Identity=24.7357293868922, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI87081878, Length=487, Percent_Identity=24.0246406570842, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI1789397, Length=507, Percent_Identity=23.8658777120316, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 56640; Mature: 56509

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGISPQALATDLKIGMSSPPTSMDPHFYNLFSNINVSEHMFECLVKMDADSHIVPGLAE
CCCCCCHHHHHHHEECCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHHH
SWKMVNNLTWEFKLRPGVKFHDGSELTTEDVAWSLDRPATIVNSPGKFDTYTKAIIHKKI
HHHHHHCCEEEEEECCCCEECCCCCCCHHHHEECCCCCCEEECCCCCCHHHHHHHHHHHH
IDKYTIQLTTSQPYPLMLSDLTSVFIVQKKATQGLSSDDFAQGKGMVGTGPFKFVSYARD
HCEEEEEEECCCCCCHHHHHHHHEEEEEEHHHCCCCCCCHHCCCCCCCCCCHHHHHHCCC
DRVELVRNDQYWGPKPAWDKVTLRFIPNGATRIAALLSGDVQAIENVPTPDLARVRGDAS
CCEEEEECCCCCCCCCCCCCEEEEEECCCHHHHHHHHHCCHHHHHCCCCCHHHHHCCCCC
LNFFSKISHRVIYLYTDDKRDPTPDVTGKDGKPLAKNPLKDPRVRRAMSMTINRQGIKDR
HHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHH
IMEGLAEPTDNLVPPQLFGYNPNLKTLKYDPEGAKKLLAEAGYPDGFGITLHTPNNRYVN
HHHHHCCCCCCCCCCHHCCCCCCCCEEEECCHHHHHHHHHCCCCCCCEEEEECCCCCCCC
DEKIAQTIAQNLTRIGIVTKVEGMPMATFAAKSIRHEYSFGLVGWGAQTGEVSSPLRALV
HHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHH
ACEDARKGYGTVNWGQYCNPKMDAVLDKALYTMDDKERSRLLQEATAIVVDDGGIIPVHF
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCEEEEEECCCEEEEEE
QVTTWAARKGFTYTPRTDERTYAQGFMPQ
EEEEEHHCCCCEECCCCCCCHHCCCCCCC
>Mature Secondary Structure 
AGISPQALATDLKIGMSSPPTSMDPHFYNLFSNINVSEHMFECLVKMDADSHIVPGLAE
CCCCCHHHHHHHEECCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHHH
SWKMVNNLTWEFKLRPGVKFHDGSELTTEDVAWSLDRPATIVNSPGKFDTYTKAIIHKKI
HHHHHHCCEEEEEECCCCEECCCCCCCHHHHEECCCCCCEEECCCCCCHHHHHHHHHHHH
IDKYTIQLTTSQPYPLMLSDLTSVFIVQKKATQGLSSDDFAQGKGMVGTGPFKFVSYARD
HCEEEEEEECCCCCCHHHHHHHHEEEEEEHHHCCCCCCCHHCCCCCCCCCCHHHHHHCCC
DRVELVRNDQYWGPKPAWDKVTLRFIPNGATRIAALLSGDVQAIENVPTPDLARVRGDAS
CCEEEEECCCCCCCCCCCCCEEEEEECCCHHHHHHHHHCCHHHHHCCCCCHHHHHCCCCC
LNFFSKISHRVIYLYTDDKRDPTPDVTGKDGKPLAKNPLKDPRVRRAMSMTINRQGIKDR
HHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHH
IMEGLAEPTDNLVPPQLFGYNPNLKTLKYDPEGAKKLLAEAGYPDGFGITLHTPNNRYVN
HHHHHCCCCCCCCCCHHCCCCCCCCEEEECCHHHHHHHHHCCCCCCCEEEEECCCCCCCC
DEKIAQTIAQNLTRIGIVTKVEGMPMATFAAKSIRHEYSFGLVGWGAQTGEVSSPLRALV
HHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHH
ACEDARKGYGTVNWGQYCNPKMDAVLDKALYTMDDKERSRLLQEATAIVVDDGGIIPVHF
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCEEEEEECCCEEEEEE
QVTTWAARKGFTYTPRTDERTYAQGFMPQ
EEEEEHHCCCCEECCCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]