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The map label for this gene is intZ [H]

Identifier: 17547208

GI number: 17547208

Start: 2694535

End: 2695788

Strand: Reverse

Name: intZ [H]

Synonym: RSc2489

Alternate gene names: 17547208

Gene position: 2695788-2694535 (Counterclockwise)

Preceding gene: 17547209

Following gene: 17547207

Centisome position: 72.54

GC content: 64.43

Gene sequence:

>1254_bases
ATGCGCCACTTCAACTACGCACTGACACCGACGCGGATCAACAACGCAAAGCCCAAGGAGAAGCCATACAAGCTGACGGA
CGGCGGCGGCTTGTTCGTGCTGGTATCCCCCGGTGGCGCGAAGAACTGGCGGTATCAGTACCCGATGGGCGGCAAGCGTT
GTGCCGTCACCATTGGCCGCTACCCGGAAATCAGCGTTGCGGATGCCCGCGACCGCCACGCCGAATACCGGGCGATGGTC
GAGCGCGGTGAAGACCCGGCAGCCCACAGACGCGAAGAGAAGACCGAGCGCGCGGCGCGTGCCGCACTGGATGCAGACGA
AGGCCAGTTCAAGGCGTTTTCCCTAAAGTGGATCGATGAGCGCCTGGCCGGCAAGACGGAGGGCTACCGGAAGCAGATTC
GGTCCCGCCTGGATCGGTTTGTGTGGCCGGCCATCGGACGCAAGGCGCTGGATGACGTGAAGCCCGCCCACGTGCTGGCA
ATTGTCGAGGGGCTGCGGGCGACGCCAAACACTGCTGAGGGCGTGCGCGTCATTGTTCAGCAGTGCTACGACTACGCCAT
CCAGAAGCTGCTGGTGGAGTCAAACCCAGCCCGGCCACTGCGCGGCGTCATCACCGTCCCCAAAGCGGAACACCACCGCC
ACCTGTCCGAATCCGATCTGGGCGCGTTCTGGCGGGCGCTTGGCAAGCAAGGGGCGCATCCGTCCACTACCGCCGCCGTC
TACCTGCTGGTGTACAGCATGTGCCGGAAGAACGAGGTGCTGCGGGCCAAGTGGTCGGAATTCGATTTCGACAAAGCCCA
ATGGGACATCCCGGCCGAGCGGATGAAGTCGCGCCGACCGCATCGAGTCTACCTGTCACGCCAGGCGCTGGAGGTGCTGG
AGGTGCAACGGGCCGTGAGCGGCGGCTATGAGTACGTCTTCCCGTCGCCATCTATCCCGACCTTGCCGCTGGCCGATGCC
ACGCTGAATCACCTGTTCAAGCGCCTGGACTTCGGCGTGCCGGAATTTTCCCCGCACGGTACGCGCGGTACCGCGGCGAC
GTTGCTGCGCGAGCACGGATTCAGCCGGGACGTGGTGGAGCTGCTACTGGCACACACCGAGCGCAGCCAGACGGCGGCGA
GCTATCACCACCACGAGCTGGAAGCGGAGCGCCGGCGCGCGCTGCAGTACCTAGCAGACGAAATCGACCGTCAGGCAGCT
ATTTCGGCGGCTGGCAACGTGGTGAACATCAAGGACAGGGCTACTACTGCCTGA

Upstream 100 bases:

>100_bases
GTATCAGGCAGTATCATGGAAGTACTCACTTAGTGAGGTCGATTAGGGGGCTAAGCGGGGCTGCAAAAGCCTCACTAGCC
TCATTTCTGAGGTCAAGCCT

Downstream 100 bases:

>100_bases
CAGTTACGAGCTGCGCCTAGATCGGCCAATCGAAAACCGGGCAAACCCTACCCTGCTGGCGCTGCTCCCTCATTCAACAG
GGTTGCACTAAGGGCGTGTA

Product: integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MRHFNYALTPTRINNAKPKEKPYKLTDGGGLFVLVSPGGAKNWRYQYPMGGKRCAVTIGRYPEISVADARDRHAEYRAMV
ERGEDPAAHRREEKTERAARAALDADEGQFKAFSLKWIDERLAGKTEGYRKQIRSRLDRFVWPAIGRKALDDVKPAHVLA
IVEGLRATPNTAEGVRVIVQQCYDYAIQKLLVESNPARPLRGVITVPKAEHHRHLSESDLGAFWRALGKQGAHPSTTAAV
YLLVYSMCRKNEVLRAKWSEFDFDKAQWDIPAERMKSRRPHRVYLSRQALEVLEVQRAVSGGYEYVFPSPSIPTLPLADA
TLNHLFKRLDFGVPEFSPHGTRGTAATLLREHGFSRDVVELLLAHTERSQTAASYHHHELEAERRRALQYLADEIDRQAA
ISAAGNVVNIKDRATTA

Sequences:

>Translated_417_residues
MRHFNYALTPTRINNAKPKEKPYKLTDGGGLFVLVSPGGAKNWRYQYPMGGKRCAVTIGRYPEISVADARDRHAEYRAMV
ERGEDPAAHRREEKTERAARAALDADEGQFKAFSLKWIDERLAGKTEGYRKQIRSRLDRFVWPAIGRKALDDVKPAHVLA
IVEGLRATPNTAEGVRVIVQQCYDYAIQKLLVESNPARPLRGVITVPKAEHHRHLSESDLGAFWRALGKQGAHPSTTAAV
YLLVYSMCRKNEVLRAKWSEFDFDKAQWDIPAERMKSRRPHRVYLSRQALEVLEVQRAVSGGYEYVFPSPSIPTLPLADA
TLNHLFKRLDFGVPEFSPHGTRGTAATLLREHGFSRDVVELLLAHTERSQTAASYHHHELEAERRRALQYLADEIDRQAA
ISAAGNVVNIKDRATTA
>Mature_417_residues
MRHFNYALTPTRINNAKPKEKPYKLTDGGGLFVLVSPGGAKNWRYQYPMGGKRCAVTIGRYPEISVADARDRHAEYRAMV
ERGEDPAAHRREEKTERAARAALDADEGQFKAFSLKWIDERLAGKTEGYRKQIRSRLDRFVWPAIGRKALDDVKPAHVLA
IVEGLRATPNTAEGVRVIVQQCYDYAIQKLLVESNPARPLRGVITVPKAEHHRHLSESDLGAFWRALGKQGAHPSTTAAV
YLLVYSMCRKNEVLRAKWSEFDFDKAQWDIPAERMKSRRPHRVYLSRQALEVLEVQRAVSGGYEYVFPSPSIPTLPLADA
TLNHLFKRLDFGVPEFSPHGTRGTAATLLREHGFSRDVVELLLAHTERSQTAASYHHHELEAERRRALQYLADEIDRQAA
ISAAGNVVNIKDRATTA

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI145693166, Length=403, Percent_Identity=33.7468982630273, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1788974, Length=393, Percent_Identity=31.0432569974555, Blast_Score=202, Evalue=4e-53,
Organism=Escherichia coli, GI1788690, Length=395, Percent_Identity=27.3417721518987, Blast_Score=157, Evalue=9e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 47079; Mature: 47079

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHFNYALTPTRINNAKPKEKPYKLTDGGGLFVLVSPGGAKNWRYQYPMGGKRCAVTIGR
CCCCCEEECCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCEEECCCCCCEEEEEECC
YPEISVADARDRHAEYRAMVERGEDPAAHRREEKTERAARAALDADEGQFKAFSLKWIDE
CCCCEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHH
RLAGKTEGYRKQIRSRLDRFVWPAIGRKALDDVKPAHVLAIVEGLRATPNTAEGVRVIVQ
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHH
QCYDYAIQKLLVESNPARPLRGVITVPKAEHHRHLSESDLGAFWRALGKQGAHPSTTAAV
HHHHHHHHHHHHCCCCCCCCCCEEECCCCHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHH
YLLVYSMCRKNEVLRAKWSEFDFDKAQWDIPAERMKSRRPHRVYLSRQALEVLEVQRAVS
HHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCEEHHHHHHHHHHHHHHHHH
GGYEYVFPSPSIPTLPLADATLNHLFKRLDFGVPEFSPHGTRGTAATLLREHGFSRDVVE
CCCEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHHHH
LLLAHTERSQTAASYHHHELEAERRRALQYLADEIDRQAAISAAGNVVNIKDRATTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCC
>Mature Secondary Structure
MRHFNYALTPTRINNAKPKEKPYKLTDGGGLFVLVSPGGAKNWRYQYPMGGKRCAVTIGR
CCCCCEEECCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCEEECCCCCCEEEEEECC
YPEISVADARDRHAEYRAMVERGEDPAAHRREEKTERAARAALDADEGQFKAFSLKWIDE
CCCCEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHH
RLAGKTEGYRKQIRSRLDRFVWPAIGRKALDDVKPAHVLAIVEGLRATPNTAEGVRVIVQ
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHH
QCYDYAIQKLLVESNPARPLRGVITVPKAEHHRHLSESDLGAFWRALGKQGAHPSTTAAV
HHHHHHHHHHHHCCCCCCCCCCEEECCCCHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHH
YLLVYSMCRKNEVLRAKWSEFDFDKAQWDIPAERMKSRRPHRVYLSRQALEVLEVQRAVS
HHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCEEHHHHHHHHHHHHHHHHH
GGYEYVFPSPSIPTLPLADATLNHLFKRLDFGVPEFSPHGTRGTAATLLREHGFSRDVVE
CCCEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHHHH
LLLAHTERSQTAASYHHHELEAERRRALQYLADEIDRQAAISAAGNVVNIKDRATTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]