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The map label for this gene is fkpB [H]

Identifier: 17547162

GI number: 17547162

Start: 2649651

End: 2650085

Strand: Reverse

Name: fkpB [H]

Synonym: RSc2443

Alternate gene names: 17547162

Gene position: 2650085-2649651 (Counterclockwise)

Preceding gene: 17547167

Following gene: 17547161

Centisome position: 71.31

GC content: 64.6

Gene sequence:

>435_bases
GTGGTCGGGCCGGATTCCTATCTGACGCTGCATTACCGGATCGCTCTGGAAAACGATACGGACATCGTCACCACCTTCGG
CGATAAGCCCGCCACGCTGCTGTTGGGCCAGGGCCAACTGGCGCCGACGCTGGAACAGGCGCTGCTCGGCATGCACGAGG
GTGAGCGCATGACGTTCCGGCTGGCGCCCGAGCATGCATTCGGGCCGCGCAATCCCGATCTGCTGCAGCGCGTATCGCTG
GCCACGCTGCGCGAGAACTCCTCGTTCGAGGAGGACTACCAGCCCGGCGATCTCGTCGAGTTCAACGCCCCCAGCGGCGG
CAAGTACGCGGGCGTGCTGAAGGAGGTCGGTGAGACCGCGGCGCTGTTCGATTTCAATCATCCGCTGGCCGGGCAGACCA
TCCTGTTCGAAGTCCAGCTGATCGGCATCCTGTGA

Upstream 100 bases:

>100_bases
GAGGGGTGGTGCTGACGTACAATACCTGGTTACTTTTTGGTCGAGCAGGTCAAGCGTGCAAAATTTGGTGAACGGGGCGC
CGGCAGGCGGCGCAGGCAAA

Downstream 100 bases:

>100_bases
TGAGCACGACCGAGAACGCTGCGATCGAACCCGTGACCGGCGCCGACGCCGAAGTCCTGCTGGCGCAGCCGCGCGGCTTC
TGCGCCGGCGTGGACCGCGC

Product: FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MVGPDSYLTLHYRIALENDTDIVTTFGDKPATLLLGQGQLAPTLEQALLGMHEGERMTFRLAPEHAFGPRNPDLLQRVSL
ATLRENSSFEEDYQPGDLVEFNAPSGGKYAGVLKEVGETAALFDFNHPLAGQTILFEVQLIGIL

Sequences:

>Translated_144_residues
MVGPDSYLTLHYRIALENDTDIVTTFGDKPATLLLGQGQLAPTLEQALLGMHEGERMTFRLAPEHAFGPRNPDLLQRVSL
ATLRENSSFEEDYQPGDLVEFNAPSGGKYAGVLKEVGETAALFDFNHPLAGQTILFEVQLIGIL
>Mature_144_residues
MVGPDSYLTLHYRIALENDTDIVTTFGDKPATLLLGQGQLAPTLEQALLGMHEGERMTFRLAPEHAFGPRNPDLLQRVSL
ATLRENSSFEEDYQPGDLVEFNAPSGGKYAGVLKEVGETAALFDFNHPLAGQTILFEVQLIGIL

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786211, Length=145, Percent_Identity=35.8620689655172, Blast_Score=87, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 15771; Mature: 15771

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGPDSYLTLHYRIALENDTDIVTTFGDKPATLLLGQGQLAPTLEQALLGMHEGERMTFR
CCCCCCEEEEEEEEEECCCCEEEEEECCCCEEEEEECCCCCHHHHHHHHCCCCCCEEEEE
LAPEHAFGPRNPDLLQRVSLATLRENSSFEEDYQPGDLVEFNAPSGGKYAGVLKEVGETA
ECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHCCCEE
ALFDFNHPLAGQTILFEVQLIGIL
EEEECCCCCCCCEEEEEEEEEECC
>Mature Secondary Structure
MVGPDSYLTLHYRIALENDTDIVTTFGDKPATLLLGQGQLAPTLEQALLGMHEGERMTFR
CCCCCCEEEEEEEEEECCCCEEEEEECCCCEEEEEECCCCCHHHHHHHHCCCCCCEEEEE
LAPEHAFGPRNPDLLQRVSLATLRENSSFEEDYQPGDLVEFNAPSGGKYAGVLKEVGETA
ECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHCCCEE
ALFDFNHPLAGQTILFEVQLIGIL
EEEECCCCCCCCEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2121716 [H]