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The map label for this gene is livK [C]

Identifier: 17547160

GI number: 17547160

Start: 2647010

End: 2648020

Strand: Reverse

Name: livK [C]

Synonym: RSc2441

Alternate gene names: 17547160

Gene position: 2648020-2647010 (Counterclockwise)

Preceding gene: 17547161

Following gene: 17547159

Centisome position: 71.25

GC content: 61.03

Gene sequence:

>1011_bases
TTGGGCAAAGACAACGAAAACGGTGCACGCCTGGCCGTGGAAGATGTCAACAAGGAAGGGCTGACCATCGACGGCAAGAA
GATCAAGCTGGAGCTGGTGGGCGAGGATGATGCGGCTGATCCGAAGACGGGTACGGCCGTTGCGCAAAAGCTGGTGGACG
AGAAAGTCGTCGCCGTCGTGGGCCACCTGAACTCGGGCGTGTCGATCCCGGCCTCGAAGATTTACAGCGATGCCGGCATC
GTGCAGATCTCGCCGTCGTCGACCAACCCCGACTACACCAAGCAGGGCTTCAAGACGACCTACCGCGTGGTTGCGACCGA
CGCGCAGCAGGGTCCGGCCCTGGCCAACTACGCCGCCAAGACCCTGGGCGCCAAGAGCGTGGCGATCGTCGACGATGCCA
CCGCCTACGGCAAGGGCCTGGCCGACGAGTTCGAGAAGACCGCGAAGGCCGACGGCGTGAACGTGGTGGCACGTGAAGCC
ACCAACGACAAGGCCACCGACTTCAAGGCCATTCTGACCAAGATCAAGGGCAAGAAGCCGGACGTGATCATGTACGGCGG
CATGGACGCCACCGGCGGTCCGTTCGCCAAGCAGGCCAAGGAACTGGGCATCACGGCCAAGATCGTTGGCGGCGACGGCG
TGTGCACCGACAAGGTGGCCGAACTGGCCGGCGACGCCATCGACAATATCATCTGCTCGGAAGCGGGCCTGGCGCTGTCG
AAGATGGAGAAGGGCGCGGACTTCGAGAAGAAGTACGAAGACCGCTTCAAGACGCCGGTGCAGATCTACGCACCGTTCAC
GTATGACGCCGTGATGGTCGTCGTCGATGCGATGAAGCGCTCCAACTCGGTGGACCCCGCCAAGATCCTGGCTGCCATGC
CGACAACCAATTATCACGGCGTGATCGGCAACATCGCGTTCGACGACAAGGGTGACCTGAAGGAAGGTTCGATCACCCTG
TACAACTACAAGGACAAAAAGAAGACCGTTCTTGACGTCGTGAAGATGTAA

Upstream 100 bases:

>100_bases
GCCTGCTGCAACGTCGGCCCCGGCCGCTGCTGCTGCCGGTGGTGGTGAGACCGTCATCAAGATTGGTCACGCCGCACCGT
TGACGGGTGGTATCGCTCAC

Downstream 100 bases:

>100_bases
TCGAGGGGTTATCCGCCCTGGAAAACGGCACCGCGCCTTACCCTAGCGGTGCCGTTTTTTATCGCCTCGCCAGTTACACA
AGACCCTCACCATGGGTGCG

Product: amino acid-binding periplasmic ABC transporter protein

Products: ADP; phosphate; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MGKDNENGARLAVEDVNKEGLTIDGKKIKLELVGEDDAADPKTGTAVAQKLVDEKVVAVVGHLNSGVSIPASKIYSDAGI
VQISPSSTNPDYTKQGFKTTYRVVATDAQQGPALANYAAKTLGAKSVAIVDDATAYGKGLADEFEKTAKADGVNVVAREA
TNDKATDFKAILTKIKGKKPDVIMYGGMDATGGPFAKQAKELGITAKIVGGDGVCTDKVAELAGDAIDNIICSEAGLALS
KMEKGADFEKKYEDRFKTPVQIYAPFTYDAVMVVVDAMKRSNSVDPAKILAAMPTTNYHGVIGNIAFDDKGDLKEGSITL
YNYKDKKKTVLDVVKM

Sequences:

>Translated_336_residues
MGKDNENGARLAVEDVNKEGLTIDGKKIKLELVGEDDAADPKTGTAVAQKLVDEKVVAVVGHLNSGVSIPASKIYSDAGI
VQISPSSTNPDYTKQGFKTTYRVVATDAQQGPALANYAAKTLGAKSVAIVDDATAYGKGLADEFEKTAKADGVNVVAREA
TNDKATDFKAILTKIKGKKPDVIMYGGMDATGGPFAKQAKELGITAKIVGGDGVCTDKVAELAGDAIDNIICSEAGLALS
KMEKGADFEKKYEDRFKTPVQIYAPFTYDAVMVVVDAMKRSNSVDPAKILAAMPTTNYHGVIGNIAFDDKGDLKEGSITL
YNYKDKKKTVLDVVKM
>Mature_335_residues
GKDNENGARLAVEDVNKEGLTIDGKKIKLELVGEDDAADPKTGTAVAQKLVDEKVVAVVGHLNSGVSIPASKIYSDAGIV
QISPSSTNPDYTKQGFKTTYRVVATDAQQGPALANYAAKTLGAKSVAIVDDATAYGKGLADEFEKTAKADGVNVVAREAT
NDKATDFKAILTKIKGKKPDVIMYGGMDATGGPFAKQAKELGITAKIVGGDGVCTDKVAELAGDAIDNIICSEAGLALSK
MEKGADFEKKYEDRFKTPVQIYAPFTYDAVMVVVDAMKRSNSVDPAKILAAMPTTNYHGVIGNIAFDDKGDLKEGSITLY
NYKDKKKTVLDVVKM

Specific function: Component of an amino-acid transport system (Potential) [H]

COG id: COG0683

COG function: function code E; ABC-type branched-chain amino acid transport systems, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the leucine-binding protein family [H]

Homologues:

Organism=Escherichia coli, GI1789867, Length=325, Percent_Identity=32.6153846153846, Blast_Score=174, Evalue=5e-45,
Organism=Escherichia coli, GI48994941, Length=326, Percent_Identity=30.6748466257669, Blast_Score=153, Evalue=2e-38,

Paralogues:

None

Copy number: 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001828
- InterPro:   IPR000709 [H]

Pfam domain/function: PF01094 ANF_receptor [H]

EC number: NA

Molecular weight: Translated: 35544; Mature: 35413

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKDNENGARLAVEDVNKEGLTIDGKKIKLELVGEDDAADPKTGTAVAQKLVDEKVVAVV
CCCCCCCCCEEEEEECCCCCCEECCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
GHLNSGVSIPASKIYSDAGIVQISPSSTNPDYTKQGFKTTYRVVATDAQQGPALANYAAK
HHCCCCCCCCHHHHHCCCCEEEECCCCCCCCHHHHHHHEEEEEEEECCCCCCHHHHHHHH
TLGAKSVAIVDDATAYGKGLADEFEKTAKADGVNVVAREATNDKATDFKAILTKIKGKKP
HCCCCEEEEEECCHHHCCCHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCC
DVIMYGGMDATGGPFAKQAKELGITAKIVGGDGVCTDKVAELAGDAIDNIICSEAGLALS
CEEEECCCCCCCCHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHH
KMEKGADFEKKYEDRFKTPVQIYAPFTYDAVMVVVDAMKRSNSVDPAKILAAMPTTNYHG
HHHCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCHHHHEEECCCCCCCC
VIGNIAFDDKGDLKEGSITLYNYKDKKKTVLDVVKM
EEEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHCC
>Mature Secondary Structure 
GKDNENGARLAVEDVNKEGLTIDGKKIKLELVGEDDAADPKTGTAVAQKLVDEKVVAVV
CCCCCCCCEEEEEECCCCCCEECCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
GHLNSGVSIPASKIYSDAGIVQISPSSTNPDYTKQGFKTTYRVVATDAQQGPALANYAAK
HHCCCCCCCCHHHHHCCCCEEEECCCCCCCCHHHHHHHEEEEEEEECCCCCCHHHHHHHH
TLGAKSVAIVDDATAYGKGLADEFEKTAKADGVNVVAREATNDKATDFKAILTKIKGKKP
HCCCCEEEEEECCHHHCCCHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCC
DVIMYGGMDATGGPFAKQAKELGITAKIVGGDGVCTDKVAELAGDAIDNIICSEAGLALS
CEEEECCCCCCCCHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHH
KMEKGADFEKKYEDRFKTPVQIYAPFTYDAVMVVVDAMKRSNSVDPAKILAAMPTTNYHG
HHHCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCHHHHEEECCCCCCCC
VIGNIAFDDKGDLKEGSITLYNYKDKKKTVLDVVKM
EEEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-leucine [Periplasm]; H2O [C]

Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA