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The map label for this gene is yebQ [C]

Identifier: 17547043

GI number: 17547043

Start: 2523838

End: 2525265

Strand: Reverse

Name: yebQ [C]

Synonym: RSc2324

Alternate gene names: 17547043

Gene position: 2525265-2523838 (Counterclockwise)

Preceding gene: 17547045

Following gene: 17547042

Centisome position: 67.95

GC content: 69.96

Gene sequence:

>1428_bases
ATGAGTTCAACCTCGATCACCGCAGACGACGCCTCCTGGCTCGATCTGTTTCGCGGTGCCAACGCGCTGCGCGTGCTGGT
GCTGGCCGCAGGCGTGGCGCTGCACGCCATCAACCTCTACCTGACCACGACGATCCTGCCGAGCGTGGTCGACGACATCG
GCGGCGTGGCGTTCTATGCGTGGAATACGACGCTGTTCATCGTCGCGTCGATCACCGGGGCTGCCGTGGCGGCGCAGGTG
ATCCAGCATCTCGGGCCGCGCGGCGCCTACCTGCTGGGCGCCATGGTGTTCGGCGGCGGCTCGGCGCTGTGTGCACTGGC
ACCGATCATGCAGGTACTGCTGGTGGGCCGCGTGCTGCAGGGGTTGGGCGGGGGCGTGCTGCTGTCGGCGCCGTATGTGC
TGATGCGCAGCGTGCTGCCCGAACCCCTGTGGCCGCGTGCGCTGGCGCTGCTCTCGGGCATGTGGGGCATTGCGACATTG
CTCGGGCCGGCTGTGGGCGGCATCTTTGCGCAGTACGCGACGTGGCGGCTGGCGTTCTGGTCGCTGGTCGTGCTGATTGC
GCTGGCGGCGGCTGCAGCCGTGGTCGTGCTGAAACCGGCAGCCCCCCAGGCAGAACGTCCGACGCCGGTGCCGACGCGCC
AGCTCGTGCTTCTCGCGGTTGCCGTGGTGGCAGCGTCGTGGGCCAGCGTCAGCGACTCGCCGTGGCTGGGCGCACTCGGC
TTGATCGCGGCCGCTCTCACACTGCTGGCAATCCGTCGTGTGGAGATGCGCTCATCACGCCGCATCCTGCCCGCCGATGC
GTACACGGGCCGCACGGCGCTCGCCGCGCTGTATGGCGTGTCTGCGCTGCTGGCCGTTACGGTCACGTGCACGGAGATTT
TCGTGCCGCTGTTCCTGCAACGGCTGCATGGGCAGAGCCCGCTGATTGCCGGCTACATCGCGGCCACGGCGTCGGCCGGC
TGGACGCTCGGCGCCATCCTGAGCGCTGCGCTGCGCGCGGCGTCGGTCACACGCGCGATCCGCTTGGCACCGTGGGCGTG
CGCGCTGGGCTTGCTGGTACTGGCGATGCTGGTGCCGATAGGCGCGGGCAGCGCGTGGATGACCACGCTGATCATCGTCG
CGCTCACGCTGGTGGGACTGGGCGTGGGCGTTGTGTGGCCGCACCTGGGCAACCGCATCATGACGGCGGCGCCGGCGGAA
GACCATGACCGCGCATCGGCGTCGATCGTGACGGTGCAGTTGGTGGCGACGGCGTTGGGGGCAGCGCTGGGTGGGGTGGT
GCTCAACACGTTGGGCGCGGCGGGCCCGGCGCCTGATCTGGGAGCAGCGTCGCGCTGGCTGTTCCTGCTGTTTGCGGTGG
CGCCGGTGGGGGCGCTGGTGATTGCGCACACGGGGCTCCGCACCCGGCTCACCTCTTCGACACGCTAG

Upstream 100 bases:

>100_bases
ATAATGCGATACCGAGCGGTACGACGCAAGCGAGCTGCCACAGGTCTGTGAACTCCCGCGTCTATTGGGTATCCCCCCCA
TTCCCTTGCCGGAGCCCAAG

Downstream 100 bases:

>100_bases
ACGGGCGTTGAGCCCAGCAGTCTGCCACCGCACAGAGAACAACGCTGCACGAACGCTCCTCAGCATGCCGCCGAAGACGC
GGCGCTGCCAGCGGGCAGCC

Product: transport transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MSSTSITADDASWLDLFRGANALRVLVLAAGVALHAINLYLTTTILPSVVDDIGGVAFYAWNTTLFIVASITGAAVAAQV
IQHLGPRGAYLLGAMVFGGGSALCALAPIMQVLLVGRVLQGLGGGVLLSAPYVLMRSVLPEPLWPRALALLSGMWGIATL
LGPAVGGIFAQYATWRLAFWSLVVLIALAAAAAVVVLKPAAPQAERPTPVPTRQLVLLAVAVVAASWASVSDSPWLGALG
LIAAALTLLAIRRVEMRSSRRILPADAYTGRTALAALYGVSALLAVTVTCTEIFVPLFLQRLHGQSPLIAGYIAATASAG
WTLGAILSAALRAASVTRAIRLAPWACALGLLVLAMLVPIGAGSAWMTTLIIVALTLVGLGVGVVWPHLGNRIMTAAPAE
DHDRASASIVTVQLVATALGAALGGVVLNTLGAAGPAPDLGAASRWLFLLFAVAPVGALVIAHTGLRTRLTSSTR

Sequences:

>Translated_475_residues
MSSTSITADDASWLDLFRGANALRVLVLAAGVALHAINLYLTTTILPSVVDDIGGVAFYAWNTTLFIVASITGAAVAAQV
IQHLGPRGAYLLGAMVFGGGSALCALAPIMQVLLVGRVLQGLGGGVLLSAPYVLMRSVLPEPLWPRALALLSGMWGIATL
LGPAVGGIFAQYATWRLAFWSLVVLIALAAAAAVVVLKPAAPQAERPTPVPTRQLVLLAVAVVAASWASVSDSPWLGALG
LIAAALTLLAIRRVEMRSSRRILPADAYTGRTALAALYGVSALLAVTVTCTEIFVPLFLQRLHGQSPLIAGYIAATASAG
WTLGAILSAALRAASVTRAIRLAPWACALGLLVLAMLVPIGAGSAWMTTLIIVALTLVGLGVGVVWPHLGNRIMTAAPAE
DHDRASASIVTVQLVATALGAALGGVVLNTLGAAGPAPDLGAASRWLFLLFAVAPVGALVIAHTGLRTRLTSSTR
>Mature_474_residues
SSTSITADDASWLDLFRGANALRVLVLAAGVALHAINLYLTTTILPSVVDDIGGVAFYAWNTTLFIVASITGAAVAAQVI
QHLGPRGAYLLGAMVFGGGSALCALAPIMQVLLVGRVLQGLGGGVLLSAPYVLMRSVLPEPLWPRALALLSGMWGIATLL
GPAVGGIFAQYATWRLAFWSLVVLIALAAAAAVVVLKPAAPQAERPTPVPTRQLVLLAVAVVAASWASVSDSPWLGALGL
IAAALTLLAIRRVEMRSSRRILPADAYTGRTALAALYGVSALLAVTVTCTEIFVPLFLQRLHGQSPLIAGYIAATASAGW
TLGAILSAALRAASVTRAIRLAPWACALGLLVLAMLVPIGAGSAWMTTLIIVALTLVGLGVGVVWPHLGNRIMTAAPAED
HDRASASIVTVQLVATALGAALGGVVLNTLGAAGPAPDLGAASRWLFLLFAVAPVGALVIAHTGLRTRLTSSTR

Specific function: Could be involved in fluoroquinolones efflux [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=421, Percent_Identity=24.7030878859857, Blast_Score=83, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48635; Mature: 48504

Theoretical pI: Translated: 10.66; Mature: 10.66

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTSITADDASWLDLFRGANALRVLVLAAGVALHAINLYLTTTILPSVVDDIGGVAFYA
CCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEE
WNTTLFIVASITGAAVAAQVIQHLGPRGAYLLGAMVFGGGSALCALAPIMQVLLVGRVLQ
ECCEEEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
GLGGGVLLSAPYVLMRSVLPEPLWPRALALLSGMWGIATLLGPAVGGIFAQYATWRLAFW
HCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLVVLIALAAAAAVVVLKPAAPQAERPTPVPTRQLVLLAVAVVAASWASVSDSPWLGALG
HHHHHHHHHHHHHHHEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
LIAAALTLLAIRRVEMRSSRRILPADAYTGRTALAALYGVSALLAVTVTCTEIFVPLFLQ
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLHGQSPLIAGYIAATASAGWTLGAILSAALRAASVTRAIRLAPWACALGLLVLAMLVPI
HHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GAGSAWMTTLIIVALTLVGLGVGVVWPHLGNRIMTAAPAEDHDRASASIVTVQLVATALG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHH
AALGGVVLNTLGAAGPAPDLGAASRWLFLLFAVAPVGALVIAHTGLRTRLTSSTR
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCC
>Mature Secondary Structure 
SSTSITADDASWLDLFRGANALRVLVLAAGVALHAINLYLTTTILPSVVDDIGGVAFYA
CCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEE
WNTTLFIVASITGAAVAAQVIQHLGPRGAYLLGAMVFGGGSALCALAPIMQVLLVGRVLQ
ECCEEEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
GLGGGVLLSAPYVLMRSVLPEPLWPRALALLSGMWGIATLLGPAVGGIFAQYATWRLAFW
HCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLVVLIALAAAAAVVVLKPAAPQAERPTPVPTRQLVLLAVAVVAASWASVSDSPWLGALG
HHHHHHHHHHHHHHHEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
LIAAALTLLAIRRVEMRSSRRILPADAYTGRTALAALYGVSALLAVTVTCTEIFVPLFLQ
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLHGQSPLIAGYIAATASAGWTLGAILSAALRAASVTRAIRLAPWACALGLLVLAMLVPI
HHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GAGSAWMTTLIIVALTLVGLGVGVVWPHLGNRIMTAAPAEDHDRASASIVTVQLVATALG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHH
AALGGVVLNTLGAAGPAPDLGAASRWLFLLFAVAPVGALVIAHTGLRTRLTSSTR
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]