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The map label for this gene is aapM [H]

Identifier: 17546978

GI number: 17546978

Start: 2451063

End: 2451755

Strand: Direct

Name: aapM [H]

Synonym: RSc2259

Alternate gene names: 17546978

Gene position: 2451063-2451755 (Clockwise)

Preceding gene: 17546977

Following gene: 17546979

Centisome position: 65.95

GC content: 68.83

Gene sequence:

>693_bases
ATGCTCGAACTCATCCAGACCTACGGCCTCTACTACCTGATTGGACAGTATCCGAACGGCCCCCTGGGCGGCCTGGCGCT
CACGCTGCTGCTGGCCGCCGCCGGCCTGGTGCTGGCGCTGCCCGCGGGCATCCTGCTCGGCCTGTGCCGGGTCAGCCCGT
TCCGGCTGCTGCGCTGGCCGGCCACGGCGCTGGTCTACGTGGTGCGCGGCACGCCGCTGCTGATGGTGATCTTCTGGGCG
TACTTCCTGCTGCCCACGCTCACCGGCCAGCGCACCGACCAGTTCAACACCATGCTGACCGCGCTGGTGGTCTTCGATGC
CGCGTACCTGGCCGAGATCGTCCGCGCGGGCATCCAGGCCCTGCCGCGCGGGCAGATGGAGAGCGCGCGCTCGCTGGGCC
TGCCGTACCTGCAGGCGATGCGGCTGGTGCTCCTGCCGCAGGCGCTGCGCAACATGCTGCCCTCGCTGGTCAACCAGCTC
GTGTCCACCATCAAGGAGACCTCGCTCGGCTACATCATCAGCCTGCCCGAAGTGTCGTTCGTGGCCGGGCAGATCAGTAC
GTCGGTCATGACCCAGTCGGCCGAGGTGTACGGCCTGCTGGCGCTGAGCTACTTCGCGATGTGCTTTGGCCTGACCCGCG
TGGCCTTCCTGCTGGAGCGGCGCCTGGCGGCGCGCGCACTGACCCAACCATGA

Upstream 100 bases:

>100_bases
CGTTCGCCTTCGCCACGGCGGCCTATCTGTCCATTTCGATGGCGATCACGGTGTTTTCGGCGTGGTACCAGCATCGCTAC
CCCGTGCGGACCCTGTGACC

Downstream 100 bases:

>100_bases
ACATGATCACCATCGAGCATGTCGACAAGTGGTACGGCGACTACCACGCGCTGGTCGACGTCAACGAAACCGTCGCCAAG
GGAGAAGTCGTGGTGGTGTG

Product: amino acid ABC transporter transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MLELIQTYGLYYLIGQYPNGPLGGLALTLLLAAAGLVLALPAGILLGLCRVSPFRLLRWPATALVYVVRGTPLLMVIFWA
YFLLPTLTGQRTDQFNTMLTALVVFDAAYLAEIVRAGIQALPRGQMESARSLGLPYLQAMRLVLLPQALRNMLPSLVNQL
VSTIKETSLGYIISLPEVSFVAGQISTSVMTQSAEVYGLLALSYFAMCFGLTRVAFLLERRLAARALTQP

Sequences:

>Translated_230_residues
MLELIQTYGLYYLIGQYPNGPLGGLALTLLLAAAGLVLALPAGILLGLCRVSPFRLLRWPATALVYVVRGTPLLMVIFWA
YFLLPTLTGQRTDQFNTMLTALVVFDAAYLAEIVRAGIQALPRGQMESARSLGLPYLQAMRLVLLPQALRNMLPSLVNQL
VSTIKETSLGYIISLPEVSFVAGQISTSVMTQSAEVYGLLALSYFAMCFGLTRVAFLLERRLAARALTQP
>Mature_230_residues
MLELIQTYGLYYLIGQYPNGPLGGLALTLLLAAAGLVLALPAGILLGLCRVSPFRLLRWPATALVYVVRGTPLLMVIFWA
YFLLPTLTGQRTDQFNTMLTALVVFDAAYLAEIVRAGIQALPRGQMESARSLGLPYLQAMRLVLLPQALRNMLPSLVNQL
VSTIKETSLGYIISLPEVSFVAGQISTSVMTQSAEVYGLLALSYFAMCFGLTRVAFLLERRLAARALTQP

Specific function: Part of a binding-protein-dependent transport system for L-amino acids, affects the uptake as well as efflux of these amino acids. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082239, Length=219, Percent_Identity=37.8995433789954, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1786873, Length=209, Percent_Identity=34.4497607655502, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1788226, Length=201, Percent_Identity=36.318407960199, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1787030, Length=209, Percent_Identity=32.0574162679426, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI48994930, Length=127, Percent_Identity=39.3700787401575, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786874, Length=211, Percent_Identity=28.436018957346, Blast_Score=84, Evalue=5e-18,
Organism=Escherichia coli, GI1788645, Length=207, Percent_Identity=27.0531400966184, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787087, Length=191, Percent_Identity=28.7958115183246, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1787086, Length=206, Percent_Identity=29.126213592233, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 25099; Mature: 25099

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLELIQTYGLYYLIGQYPNGPLGGLALTLLLAAAGLVLALPAGILLGLCRVSPFRLLRWP
CHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
ATALVYVVRGTPLLMVIFWAYFLLPTLTGQRTDQFNTMLTALVVFDAAYLAEIVRAGIQA
HHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPRGQMESARSLGLPYLQAMRLVLLPQALRNMLPSLVNQLVSTIKETSLGYIISLPEVSF
CCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHH
VAGQISTSVMTQSAEVYGLLALSYFAMCFGLTRVAFLLERRLAARALTQP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLELIQTYGLYYLIGQYPNGPLGGLALTLLLAAAGLVLALPAGILLGLCRVSPFRLLRWP
CHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
ATALVYVVRGTPLLMVIFWAYFLLPTLTGQRTDQFNTMLTALVVFDAAYLAEIVRAGIQA
HHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPRGQMESARSLGLPYLQAMRLVLLPQALRNMLPSLVNQLVSTIKETSLGYIISLPEVSF
CCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHH
VAGQISTSVMTQSAEVYGLLALSYFAMCFGLTRVAFLLERRLAARALTQP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8898392 [H]