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The map label for this gene is glnM [H]

Identifier: 17546977

GI number: 17546977

Start: 2450365

End: 2451060

Strand: Direct

Name: glnM [H]

Synonym: RSc2258

Alternate gene names: 17546977

Gene position: 2450365-2451060 (Clockwise)

Preceding gene: 17546976

Following gene: 17546978

Centisome position: 65.93

GC content: 66.52

Gene sequence:

>696_bases
ATGCCCAATTTCGATCTGTCGATGCTGCTGTCGGGGCAGTATCACCAGTGGCTCGTCACCGGTTTCCAGCTGTCGATCAA
GCTGACCGCGCTGGCCTTCGTGCTGGCCCTGCCGCTGGCCATCGCGGTGGCGCTGCTGCGCCTGGCGCCGGCGGCGCCGC
TGCGGGCGGTCGGCCAGGCCTATGTCGAGGCCATCCGCAACGTGCCGCTGCTCGCCCACATGCTGTTCTGGTACTTCGGC
GCGCCGCAGCTGCTGCCGATGTCCGTCAAGACCTGGCTCTACAACCTCAATTACGAAGCGGCGAGCGCGGTCATCGCGCT
CGTGCTCTATACGGCCGCCTACATGGCGGAGGACATCCGCAGCGGCCTGCGCTCGATCCCGAAGGAGCAGTTCGAGGCCA
GCCGCGCGCTGGGCCTGAGCTTCCTGCAGGCCATGCGGCTGGTGGTGCTGCCGCAATCGCTGCGCGTGACCGTGCCGCCG
CTGGTCAGCCAGACGCTGAACCTGTGGAAGAACTCCAGCATCGCCATGGTGATCGGCGTGGCGGAGCTGATGTACCAGGC
GCAGCAGGTGGAAAGCGCCACCTTCCGCGGCTTCGAGGCGTTCGCCTTCGCCACGGCGGCCTATCTGTCCATTTCGATGG
CGATCACGGTGTTTTCGGCGTGGTACCAGCATCGCTACCCCGTGCGGACCCTGTGA

Upstream 100 bases:

>100_bases
CCAAGATGAACTTCGGCCCGCGCAGCTTCAAGCTGTCGACCGACAAGATCGACTGAGTACCCGCCGCGCCGCCCGGACGC
CCTCCGGGCGGCGGAACGCC

Downstream 100 bases:

>100_bases
CCATGCTCGAACTCATCCAGACCTACGGCCTCTACTACCTGATTGGACAGTATCCGAACGGCCCCCTGGGCGGCCTGGCG
CTCACGCTGCTGCTGGCCGC

Product: amino acid ABC transporter transmembrane protein

Products: ADP; phosphate; L-glutamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MPNFDLSMLLSGQYHQWLVTGFQLSIKLTALAFVLALPLAIAVALLRLAPAAPLRAVGQAYVEAIRNVPLLAHMLFWYFG
APQLLPMSVKTWLYNLNYEAASAVIALVLYTAAYMAEDIRSGLRSIPKEQFEASRALGLSFLQAMRLVVLPQSLRVTVPP
LVSQTLNLWKNSSIAMVIGVAELMYQAQQVESATFRGFEAFAFATAAYLSISMAITVFSAWYQHRYPVRTL

Sequences:

>Translated_231_residues
MPNFDLSMLLSGQYHQWLVTGFQLSIKLTALAFVLALPLAIAVALLRLAPAAPLRAVGQAYVEAIRNVPLLAHMLFWYFG
APQLLPMSVKTWLYNLNYEAASAVIALVLYTAAYMAEDIRSGLRSIPKEQFEASRALGLSFLQAMRLVVLPQSLRVTVPP
LVSQTLNLWKNSSIAMVIGVAELMYQAQQVESATFRGFEAFAFATAAYLSISMAITVFSAWYQHRYPVRTL
>Mature_230_residues
PNFDLSMLLSGQYHQWLVTGFQLSIKLTALAFVLALPLAIAVALLRLAPAAPLRAVGQAYVEAIRNVPLLAHMLFWYFGA
PQLLPMSVKTWLYNLNYEAASAVIALVLYTAAYMAEDIRSGLRSIPKEQFEASRALGLSFLQAMRLVVLPQSLRVTVPPL
VSQTLNLWKNSSIAMVIGVAELMYQAQQVESATFRGFEAFAFATAAYLSISMAITVFSAWYQHRYPVRTL

Specific function: Part of the ABC transporter complex glnHMPQ involved in glutamine transport. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786874, Length=204, Percent_Identity=36.2745098039216, Blast_Score=133, Evalue=9e-33,
Organism=Escherichia coli, GI1788226, Length=209, Percent_Identity=34.9282296650718, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1786873, Length=213, Percent_Identity=29.5774647887324, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI48994930, Length=209, Percent_Identity=36.3636363636364, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI87082239, Length=219, Percent_Identity=29.2237442922374, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1787030, Length=200, Percent_Identity=30.5, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1787087, Length=221, Percent_Identity=30.7692307692308, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788645, Length=218, Percent_Identity=28.4403669724771, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 25637; Mature: 25505

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNFDLSMLLSGQYHQWLVTGFQLSIKLTALAFVLALPLAIAVALLRLAPAAPLRAVGQA
CCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
YVEAIRNVPLLAHMLFWYFGAPQLLPMSVKTWLYNLNYEAASAVIALVLYTAAYMAEDIR
HHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
SGLRSIPKEQFEASRALGLSFLQAMRLVVLPQSLRVTVPPLVSQTLNLWKNSSIAMVIGV
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHCEECCHHHHHHHHHHCCCCHHHHHHH
AELMYQAQQVESATFRGFEAFAFATAAYLSISMAITVFSAWYQHRYPVRTL
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PNFDLSMLLSGQYHQWLVTGFQLSIKLTALAFVLALPLAIAVALLRLAPAAPLRAVGQA
CCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
YVEAIRNVPLLAHMLFWYFGAPQLLPMSVKTWLYNLNYEAASAVIALVLYTAAYMAEDIR
HHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
SGLRSIPKEQFEASRALGLSFLQAMRLVVLPQSLRVTVPPLVSQTLNLWKNSSIAMVIGV
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHCEECCHHHHHHHHHHCCCCHHHHHHH
AELMYQAQQVESATFRGFEAFAFATAAYLSISMAITVFSAWYQHRYPVRTL
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamate [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamate [Periplasm] + H2O = ADP + phosphate + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7551042; 9384377 [H]