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The map label for this gene is qor [H]

Identifier: 17546903

GI number: 17546903

Start: 2366769

End: 2367743

Strand: Reverse

Name: qor [H]

Synonym: RSc2184

Alternate gene names: 17546903

Gene position: 2367743-2366769 (Counterclockwise)

Preceding gene: 17546904

Following gene: 17546901

Centisome position: 63.71

GC content: 70.56

Gene sequence:

>975_bases
ATGACGAAAGCCATCCGCATCTTTGAAACCGGCGGTCCCGAGGTGATGCAGCTCGTCGACGCCGAGGCGCCCGCGCCGGG
GCCCGGCGAAGCCCGCATCCGGCAGCATGCCATCGGGCTGAACTACATCGATGTGTATTTCCGCAGCGGCCTGTATCCGC
AGCCGCTGCCGGGCGGCATCGGCATGGAGGCTTCGGGCGTGGTGGAGGCGGTGGGCGAGGGCGTGACCCACGTCCGGCCC
GGCGACCGCGTGGCCTACGCCGGCCGTCCGACCGGCGCCTACGCCGAGGTGCGCACCATGCCGGCCGATATCCTGGTGCG
CCTGCCCGAGGCCATCGGCTTCGAGACCGGCGCGGCCATGATGCTGCAGGGGCTGACCGCGCAATACCTGCTGCGCGACA
GCTACCGCGTGCAGCCGGGCGACACCGTGCTGTTTCACGCGGCGGCCGGCGGCGTGGGCCTGATCGCTTGCCAGTGGCTC
AAGGCGCTGGGCGCCACCGTGATCGGCACCGTCGGCAGCGATGCCAAGGCGGCGCTGGCCCGCGCGCACGGCTGCGACCA
CACCATCGTCTACACGCGCGAGAACTTCACCGAGCGCGTGCGCGAGATCACCGGCGGCAAGGGCGTGCCCGTGGTCTACG
ACGGCATCGGCAAGGACACCTTCTCGGGCTCGCTGGATTGCCTCGCGCCGCGCGGCATGATGGTGAGCTATGGCAACGCA
TCCGGCCCGGTACCGCCGTTCGACCTCGGCGTGCTGAGCGCCAAGGGCTCGCTCAAGCTGACGCGCCCGACGCTGATGAC
GTACACAGCGCAGCGCGCGCTGCTGGAGCCGATGGCCGCCGAGCTGTTCGACGTGGTGGGCAGCGGCAAGGTGAAGATCG
AGATCCACCAGCGCTACGCACTGGCCGACGCGGCGCAGGCGCACCGCGACCTCGAAGCGCGCAAGACGACCGGCTCGACG
ATCCTCCTGCCGTAA

Upstream 100 bases:

>100_bases
GCGACGTCCACAACATTCCCTGCGCCACCAATCTGGCGACGGCCGACCTGGTGATGATTGCACTGGGCCTGGCGCAACCC
GACCCCAAGGAGATCCACGC

Downstream 100 bases:

>100_bases
GCCGGCGGCTACCGCCCGCTCGGCCGCACGCGCCGGGCGGCGGCAAAGCGTGCCTCCTCGCGCACGCGTTCGGGCAGGGC
GCGCAACAGCGCATGCAGCG

Product: NADPH:quinone reductase, zeta-crystallin homolog oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MTKAIRIFETGGPEVMQLVDAEAPAPGPGEARIRQHAIGLNYIDVYFRSGLYPQPLPGGIGMEASGVVEAVGEGVTHVRP
GDRVAYAGRPTGAYAEVRTMPADILVRLPEAIGFETGAAMMLQGLTAQYLLRDSYRVQPGDTVLFHAAAGGVGLIACQWL
KALGATVIGTVGSDAKAALARAHGCDHTIVYTRENFTERVREITGGKGVPVVYDGIGKDTFSGSLDCLAPRGMMVSYGNA
SGPVPPFDLGVLSAKGSLKLTRPTLMTYTAQRALLEPMAAELFDVVGSGKVKIEIHQRYALADAAQAHRDLEARKTTGST
ILLP

Sequences:

>Translated_324_residues
MTKAIRIFETGGPEVMQLVDAEAPAPGPGEARIRQHAIGLNYIDVYFRSGLYPQPLPGGIGMEASGVVEAVGEGVTHVRP
GDRVAYAGRPTGAYAEVRTMPADILVRLPEAIGFETGAAMMLQGLTAQYLLRDSYRVQPGDTVLFHAAAGGVGLIACQWL
KALGATVIGTVGSDAKAALARAHGCDHTIVYTRENFTERVREITGGKGVPVVYDGIGKDTFSGSLDCLAPRGMMVSYGNA
SGPVPPFDLGVLSAKGSLKLTRPTLMTYTAQRALLEPMAAELFDVVGSGKVKIEIHQRYALADAAQAHRDLEARKTTGST
ILLP
>Mature_323_residues
TKAIRIFETGGPEVMQLVDAEAPAPGPGEARIRQHAIGLNYIDVYFRSGLYPQPLPGGIGMEASGVVEAVGEGVTHVRPG
DRVAYAGRPTGAYAEVRTMPADILVRLPEAIGFETGAAMMLQGLTAQYLLRDSYRVQPGDTVLFHAAAGGVGLIACQWLK
ALGATVIGTVGSDAKAALARAHGCDHTIVYTRENFTERVREITGGKGVPVVYDGIGKDTFSGSLDCLAPRGMMVSYGNAS
GPVPPFDLGVLSAKGSLKLTRPTLMTYTAQRALLEPMAAELFDVVGSGKVKIEIHQRYALADAAQAHRDLEARKTTGSTI
LLP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=328, Percent_Identity=31.7073170731707, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI13236495, Length=328, Percent_Identity=31.7073170731707, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI18379349, Length=310, Percent_Identity=32.9032258064516, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI194239676, Length=211, Percent_Identity=35.0710900473934, Blast_Score=131, Evalue=6e-31,
Organism=Homo sapiens, GI22538446, Length=331, Percent_Identity=31.7220543806647, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI22538444, Length=331, Percent_Identity=31.7220543806647, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI24308257, Length=339, Percent_Identity=27.4336283185841, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI28557745, Length=244, Percent_Identity=32.3770491803279, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI41872631, Length=224, Percent_Identity=31.25, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI197927207, Length=195, Percent_Identity=28.2051282051282, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI67078404, Length=235, Percent_Identity=28.936170212766, Blast_Score=68, Evalue=9e-12,
Organism=Escherichia coli, GI1790485, Length=327, Percent_Identity=51.0703363914373, Blast_Score=332, Evalue=1e-92,
Organism=Caenorhabditis elegans, GI17507255, Length=233, Percent_Identity=30.0429184549356, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17556000, Length=268, Percent_Identity=29.4776119402985, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6319520, Length=324, Percent_Identity=40.4320987654321, Blast_Score=219, Evalue=4e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34205; Mature: 34074

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKAIRIFETGGPEVMQLVDAEAPAPGPGEARIRQHAIGLNYIDVYFRSGLYPQPLPGGI
CCCEEEEEECCCHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCC
GMEASGVVEAVGEGVTHVRPGDRVAYAGRPTGAYAEVRTMPADILVRLPEAIGFETGAAM
CCCHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCHHHHCCCHHHHHHCHHHHCCCCCHHH
MLQGLTAQYLLRDSYRVQPGDTVLFHAAAGGVGLIACQWLKALGATVIGTVGSDAKAALA
HHHHHHHHHHHHCCCEECCCCEEEEEECCCCHHHHHHHHHHHHCCCEEECCCCCHHHHHH
RAHGCDHTIVYTRENFTERVREITGGKGVPVVYDGIGKDTFSGSLDCLAPRGMMVSYGNA
HHCCCCCEEEEECHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCEEECCCCEEEEECCC
SGPVPPFDLGVLSAKGSLKLTRPTLMTYTAQRALLEPMAAELFDVVGSGKVKIEIHQRYA
CCCCCCCCCEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHH
LADAAQAHRDLEARKTTGSTILLP
HHHHHHHHHHHHHHHCCCCEEECC
>Mature Secondary Structure 
TKAIRIFETGGPEVMQLVDAEAPAPGPGEARIRQHAIGLNYIDVYFRSGLYPQPLPGGI
CCEEEEEECCCHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCC
GMEASGVVEAVGEGVTHVRPGDRVAYAGRPTGAYAEVRTMPADILVRLPEAIGFETGAAM
CCCHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCHHHHCCCHHHHHHCHHHHCCCCCHHH
MLQGLTAQYLLRDSYRVQPGDTVLFHAAAGGVGLIACQWLKALGATVIGTVGSDAKAALA
HHHHHHHHHHHHCCCEECCCCEEEEEECCCCHHHHHHHHHHHHCCCEEECCCCCHHHHHH
RAHGCDHTIVYTRENFTERVREITGGKGVPVVYDGIGKDTFSGSLDCLAPRGMMVSYGNA
HHCCCCCEEEEECHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCEEECCCCEEEEECCC
SGPVPPFDLGVLSAKGSLKLTRPTLMTYTAQRALLEPMAAELFDVVGSGKVKIEIHQRYA
CCCCCCCCCEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHH
LADAAQAHRDLEARKTTGSTILLP
HHHHHHHHHHHHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]