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The map label for this gene is mgsA

Identifier: 17546904

GI number: 17546904

Start: 2367740

End: 2368147

Strand: Reverse

Name: mgsA

Synonym: RSc2185

Alternate gene names: 17546904

Gene position: 2368147-2367740 (Counterclockwise)

Preceding gene: 17546905

Following gene: 17546903

Centisome position: 63.72

GC content: 68.87

Gene sequence:

>408_bases
GTGCCCAAGCGCCGCCGCATCGCCCTGATCGCGCACGACCACAAGAAGGACGACATGATCGCCTTCGCGCAGACGCACAA
GGCCTTCCTGATGCGATGCGACCTGCTGGCCACCGGCACCACCGGCGGCCGGCTGCAGGACGAAGTCGGCCTGAGCGTGC
AGCGCATGCTGTCCGGCCCGTGGGGCGGCGACCTGCAGATCGGGGCGCAACTGGCCGAGGGCCGCGTCGATGCCGTCATC
TTCCTGCGCGACCCGATGACGCCGCAGCCGCACGAGCCCGACATCAACGCGCTGGTCCGCGCCTGCGACGTCCACAACAT
TCCCTGCGCCACCAATCTGGCGACGGCCGACCTGGTGATGATTGCACTGGGCCTGGCGCAACCCGACCCCAAGGAGATCC
ACGCATGA

Upstream 100 bases:

>100_bases
GCCGGCTACCTGAACGCGCAGAACATCCTGCTGGATGGCGGCGCCTATCCCGGAACGTTCTGAGTCCACGACCATGACCA
CCATCACGCCCGAGGGCCCC

Downstream 100 bases:

>100_bases
CGAAAGCCATCCGCATCTTTGAAACCGGCGGTCCCGAGGTGATGCAGCTCGTCGACGCCGAGGCGCCCGCGCCGGGGCCC
GGCGAAGCCCGCATCCGGCA

Product: methylglyoxal synthase

Products: NA

Alternate protein names: MGS

Number of amino acids: Translated: 135; Mature: 134

Protein sequence:

>135_residues
MPKRRRIALIAHDHKKDDMIAFAQTHKAFLMRCDLLATGTTGGRLQDEVGLSVQRMLSGPWGGDLQIGAQLAEGRVDAVI
FLRDPMTPQPHEPDINALVRACDVHNIPCATNLATADLVMIALGLAQPDPKEIHA

Sequences:

>Translated_135_residues
MPKRRRIALIAHDHKKDDMIAFAQTHKAFLMRCDLLATGTTGGRLQDEVGLSVQRMLSGPWGGDLQIGAQLAEGRVDAVI
FLRDPMTPQPHEPDINALVRACDVHNIPCATNLATADLVMIALGLAQPDPKEIHA
>Mature_134_residues
PKRRRIALIAHDHKKDDMIAFAQTHKAFLMRCDLLATGTTGGRLQDEVGLSVQRMLSGPWGGDLQIGAQLAEGRVDAVIF
LRDPMTPQPHEPDINALVRACDVHNIPCATNLATADLVMIALGLAQPDPKEIHA

Specific function: Unknown

COG id: COG1803

COG function: function code G; Methylglyoxal synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methylglyoxal synthase family

Homologues:

Organism=Escherichia coli, GI87081809, Length=120, Percent_Identity=47.5, Blast_Score=125, Evalue=8e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MGSA_RALSO (Q8XXD0)

Other databases:

- EMBL:   AL646052
- RefSeq:   NP_520306.1
- ProteinModelPortal:   Q8XXD0
- SMR:   Q8XXD0
- GeneID:   1221029
- GenomeReviews:   AL646052_GR
- KEGG:   rso:RSc2185
- NMPDR:   fig|267608.1.peg.2185
- HOGENOM:   HBG298005
- OMA:   EPQPHDP
- ProtClustDB:   PRK05234
- BioCyc:   RSOL267608:RSC2185-MONOMER
- BRENDA:   4.2.3.3
- HAMAP:   MF_00549
- InterPro:   IPR004363
- InterPro:   IPR018148
- InterPro:   IPR011607
- Gene3D:   G3DSA:3.40.50.1380
- PIRSF:   PIRSF006614
- SMART:   SM00851
- TIGRFAMs:   TIGR00160

Pfam domain/function: PF02142 MGS; SSF52335 MGS-like_dom

EC number: =4.2.3.3

Molecular weight: Translated: 14693; Mature: 14562

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS01335 METHYLGLYOXAL_SYNTH

Important sites: ACT_SITE 64-64

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKRRRIALIAHDHKKDDMIAFAQTHKAFLMRCDLLATGTTGGRLQDEVGLSVQRMLSGP
CCCCCEEEEEECCCCCCCEEEHHHHHHHHHHHHHEEEECCCCCCCCHHHCHHHHHHHCCC
WGGDLQIGAQLAEGRVDAVIFLRDPMTPQPHEPDINALVRACDVHNIPCATNLATADLVM
CCCCCEECCEECCCCEEEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHH
IALGLAQPDPKEIHA
HHHHCCCCCHHHCCC
>Mature Secondary Structure 
PKRRRIALIAHDHKKDDMIAFAQTHKAFLMRCDLLATGTTGGRLQDEVGLSVQRMLSGP
CCCCEEEEEECCCCCCCEEEHHHHHHHHHHHHHEEEECCCCCCCCHHHCHHHHHHHCCC
WGGDLQIGAQLAEGRVDAVIFLRDPMTPQPHEPDINALVRACDVHNIPCATNLATADLVM
CCCCCEECCEECCCCEEEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHH
IALGLAQPDPKEIHA
HHHHCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852