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The map label for this gene is agaZ [H]

Identifier: 17546864

GI number: 17546864

Start: 2327924

End: 2329279

Strand: Reverse

Name: agaZ [H]

Synonym: RSc2145

Alternate gene names: 17546864

Gene position: 2329279-2327924 (Counterclockwise)

Preceding gene: 17546865

Following gene: 17546863

Centisome position: 62.68

GC content: 70.13

Gene sequence:

>1356_bases
ATGCCCGGCCTGACGAACACGCTCGAACGCCCGCGTGCCTCGCACACCGAGGCGGTGCTGCGCGTGATCTTCGACGCGAA
TCGCGGGGACGCGCAGCGCGGCATCTATTCGGTCTGCAGTGCGCACACCTTCGTGCTCGAAGCGGCGTGTGAAGCGGCGC
GCGCGGATGGTTCGCCGCTCCTGATCGAAGCCACCTGCAACCAGGTCAACCATCTCGGCGGCTATACCGGGATGACGCCG
GCCGATTTTCGTCGCGACGTCGAGGCGATTGCCGAGCGTTGCGGGCTCGCTGCCTCGGCGCTCGTGCTCGGTGGCGACCA
TCTCGGCCCGAATCCATGGCGCGACCGTCCGGCAGCCGAGGCGATGCACGAGGCGCAGACCATGGTTGCGGCGTATGTCG
AGGCCGGCTTCACGAAGATCCATCTCGATGCGAGCATGGCTTGCGCCGACGATGCCAGCCCGCTCGACGATCGCACGATC
GCGGATCGCGCCGCGCGGCTGTGCCGTGTCGCCGAGGCGGCCGCCGCGCGCGTGGGCACGCGGCCGGTCTATGTCATCGG
CACCGAGGTGCCGACACCGGGCGGCGAGACCGGCGGTGACGCGGACGGTGTCAGCGGGATCGCACGGATCGCGGTCACAC
AGGCGGACAGCATCGCGGCGACGCTTGCAGCCCACCGCGAGGCGTTCGATGCGCTCGGCCTGCAGGATGTGTGGACGCGC
GTGATCGCGATCGTCGCCCAGCCGGGTGTCGATTTCGACGACCGCCACGTGCTCGACTACGACAGCGACAAGGCCGCGGC
GCTCAGCGCGAGCATCCTGCGCACGCCGGGGCTCGTGTTCGAAGCGCACTCGACCGACTACCAGACCGACGCGGCGCTCA
CCGCGCTCGTGCGCGACCATTTCGCGATCCTGAAGGTCGGCCCGGCGCTGACGTTTGCGCTGCGCGAGGCGCTGTTCGCG
CTCAGCTATATCGAGGACGCGCTGATCGACGATCCTGCGCAGCGTTCGCGGTTGCGCGAGGTCGTCGACGCGGCGATGTG
CGCGCAGCCCGGCTACTGGGCACCGTACTATCGCGGCGACGCTGCCGCGCAGTCGCTTGCGCGGCGGTTCAGCTACAGCG
ACCGCATCCGCTATTACTGGCCGCAGCCGCGGGTCGCGGCCGCGGTCGAGCGGCTGCTGGCCAACCTCGATGCTCAGCGC
GTGCCCGAGACGCTGGTCGCGCAGTGGCTGCCCGACGTGTACGCGGCGTTCCGGAAGGGCACGCTTGCGCCGGACCCGCG
CGCGTGGGTCCGCCACCGGATTCGCGACGTGATTGCGCGGTATGCGCGCGCGTGTGGAATGCACTGGTCGGGCTGA

Upstream 100 bases:

>100_bases
CGAACGCGGCCGGCGCGCTCGCGGTCATGCAGCGCGGGCCGATGGAGGGCAACAGCCATGCGGCCGACATCGATCGTTTC
CTGGCCGAGCGGGGTGTCGC

Downstream 100 bases:

>100_bases
CCGGCTGCGCTTGGGCCGATGCCATATGAATAAAACCACAGGAGACAAACCATGCAACACAAGACGCTAACCGCCGCCGC
GCGTTTCGCTGCCGGTGCGG

Product: tagatose 6-phosphate kinase

Products: ADP; D-tagatose 1,6-bisphosphate

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MPGLTNTLERPRASHTEAVLRVIFDANRGDAQRGIYSVCSAHTFVLEAACEAARADGSPLLIEATCNQVNHLGGYTGMTP
ADFRRDVEAIAERCGLAASALVLGGDHLGPNPWRDRPAAEAMHEAQTMVAAYVEAGFTKIHLDASMACADDASPLDDRTI
ADRAARLCRVAEAAAARVGTRPVYVIGTEVPTPGGETGGDADGVSGIARIAVTQADSIAATLAAHREAFDALGLQDVWTR
VIAIVAQPGVDFDDRHVLDYDSDKAAALSASILRTPGLVFEAHSTDYQTDAALTALVRDHFAILKVGPALTFALREALFA
LSYIEDALIDDPAQRSRLREVVDAAMCAQPGYWAPYYRGDAAAQSLARRFSYSDRIRYYWPQPRVAAAVERLLANLDAQR
VPETLVAQWLPDVYAAFRKGTLAPDPRAWVRHRIRDVIARYARACGMHWSG

Sequences:

>Translated_451_residues
MPGLTNTLERPRASHTEAVLRVIFDANRGDAQRGIYSVCSAHTFVLEAACEAARADGSPLLIEATCNQVNHLGGYTGMTP
ADFRRDVEAIAERCGLAASALVLGGDHLGPNPWRDRPAAEAMHEAQTMVAAYVEAGFTKIHLDASMACADDASPLDDRTI
ADRAARLCRVAEAAAARVGTRPVYVIGTEVPTPGGETGGDADGVSGIARIAVTQADSIAATLAAHREAFDALGLQDVWTR
VIAIVAQPGVDFDDRHVLDYDSDKAAALSASILRTPGLVFEAHSTDYQTDAALTALVRDHFAILKVGPALTFALREALFA
LSYIEDALIDDPAQRSRLREVVDAAMCAQPGYWAPYYRGDAAAQSLARRFSYSDRIRYYWPQPRVAAAVERLLANLDAQR
VPETLVAQWLPDVYAAFRKGTLAPDPRAWVRHRIRDVIARYARACGMHWSG
>Mature_450_residues
PGLTNTLERPRASHTEAVLRVIFDANRGDAQRGIYSVCSAHTFVLEAACEAARADGSPLLIEATCNQVNHLGGYTGMTPA
DFRRDVEAIAERCGLAASALVLGGDHLGPNPWRDRPAAEAMHEAQTMVAAYVEAGFTKIHLDASMACADDASPLDDRTIA
DRAARLCRVAEAAAARVGTRPVYVIGTEVPTPGGETGGDADGVSGIARIAVTQADSIAATLAAHREAFDALGLQDVWTRV
IAIVAQPGVDFDDRHVLDYDSDKAAALSASILRTPGLVFEAHSTDYQTDAALTALVRDHFAILKVGPALTFALREALFAL
SYIEDALIDDPAQRSRLREVVDAAMCAQPGYWAPYYRGDAAAQSLARRFSYSDRIRYYWPQPRVAAAVERLLANLDAQRV
PETLVAQWLPDVYAAFRKGTLAPDPRAWVRHRIRDVIARYARACGMHWSG

Specific function: Component of the tagatose-1,6-bisphosphate aldolase kbaYZ that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of kbaY. When expressed alone, kbaZ does not show any aldol

COG id: COG4573

COG function: function code G; Predicted tagatose 6-phosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gatZ/kbaZ family. KbaZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789520, Length=422, Percent_Identity=51.4218009478673, Blast_Score=414, Evalue=1e-117,
Organism=Escherichia coli, GI1788411, Length=427, Percent_Identity=47.5409836065574, Blast_Score=380, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012062 [H]

Pfam domain/function: PF08013 Tagatose_6_P_K [H]

EC number: 2.7.1.144

Molecular weight: Translated: 48736; Mature: 48605

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGLTNTLERPRASHTEAVLRVIFDANRGDAQRGIYSVCSAHTFVLEAACEAARADGSPL
CCCCCCHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
LIEATCNQVNHLGGYTGMTPADFRRDVEAIAERCGLAASALVLGGDHLGPNPWRDRPAAE
EEEEHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHEECCCCCCCCCCCCCHHHH
AMHEAQTMVAAYVEAGFTKIHLDASMACADDASPLDDRTIADRAARLCRVAEAAAARVGT
HHHHHHHHHHHHHHCCCEEEEECCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
RPVYVIGTEVPTPGGETGGDADGVSGIARIAVTQADSIAATLAAHREAFDALGLQDVWTR
CCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
VIAIVAQPGVDFDDRHVLDYDSDKAAALSASILRTPGLVFEAHSTDYQTDAALTALVRDH
HHHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHH
FAILKVGPALTFALREALFALSYIEDALIDDPAQRSRLREVVDAAMCAQPGYWAPYYRGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
AAAQSLARRFSYSDRIRYYWPQPRVAAAVERLLANLDAQRVPETLVAQWLPDVYAAFRKG
HHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHCCHHHCHHHHHHHHHHHHHHHHHCC
TLAPDPRAWVRHRIRDVIARYARACGMHWSG
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PGLTNTLERPRASHTEAVLRVIFDANRGDAQRGIYSVCSAHTFVLEAACEAARADGSPL
CCCCCHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
LIEATCNQVNHLGGYTGMTPADFRRDVEAIAERCGLAASALVLGGDHLGPNPWRDRPAAE
EEEEHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHEECCCCCCCCCCCCCHHHH
AMHEAQTMVAAYVEAGFTKIHLDASMACADDASPLDDRTIADRAARLCRVAEAAAARVGT
HHHHHHHHHHHHHHCCCEEEEECCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
RPVYVIGTEVPTPGGETGGDADGVSGIARIAVTQADSIAATLAAHREAFDALGLQDVWTR
CCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
VIAIVAQPGVDFDDRHVLDYDSDKAAALSASILRTPGLVFEAHSTDYQTDAALTALVRDH
HHHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHH
FAILKVGPALTFALREALFALSYIEDALIDDPAQRSRLREVVDAAMCAQPGYWAPYYRGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
AAAQSLARRFSYSDRIRYYWPQPRVAAAVERLLANLDAQRVPETLVAQWLPDVYAAFRKG
HHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHCCHHHCHHHHHHHHHHHHHHHHHCC
TLAPDPRAWVRHRIRDVIARYARACGMHWSG
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; D-tagatose 6-phosphate

Specific reaction: ATP + D-tagatose 6-phosphate = ADP + D-tagatose 1,6-bisphosphate

General reaction: Phospho group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA