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The map label for this gene is qorA [H]

Identifier: 17546784

GI number: 17546784

Start: 2237620

End: 2238624

Strand: Reverse

Name: qorA [H]

Synonym: RSc2065

Alternate gene names: 17546784

Gene position: 2238624-2237620 (Counterclockwise)

Preceding gene: 17546785

Following gene: 17546783

Centisome position: 60.24

GC content: 70.45

Gene sequence:

>1005_bases
ATGAGAGCGATTGAAATCACGCAGTACGGCGGTCCCGACGTCCTGAAACCGGCCGAGCGGCCGATGCCGGAGCCGAAGGC
CGGCGAGGTGCTGATCCGCGTGCGCGCTGCCGGGGTGAACCGGCCCGATGTGTTCCAGCGGACCGGCAACTATCCGGTGC
CGCCGGGCGCTTCCGATATCCCGGGCCTGGAAGTGGCCGGCGAAATCGTCGGCGGCGATCTCGCGCACGCCGACAACCGG
TATGGCCTGCGCGCGGGCGATCGGGTCTGTGCGCTGGTGCAGGGCGGCGGCTACGCTGAGTTTTGCACGGCGCCGCTTGG
CCAGGTGTTGCCGGTGCCGGCGGGGTTGTCCGACATCGAGGCGGCGGCGCTGCCCGAGAACTATTTCACGGTGTGGTCCA
ACGTGTTCGACCGCGGCCAGCTGGGGCAGGGCGCGCATGGCAAGGGCGAGACGCTGCTGGTGCAGGGCGGCTCCAGTGGC
ATCGGCACCACGGCCATCCAGATGGCCTCCGCGCTCGGCTATCGCGTGTTCGCCACGGCCGGCAGCGACGAGAAGTGCGC
CGCCTGCGTCGCGCTGGGCGCGGCGCGCGCCATCCGCTACAGGACCGAGGATTTCGCCGAGGTCGTCAAGGCCGAGACGG
GGCGCGGCGTCGATGTGGTGCTCGACATGGTGGGCGGCAGCTACGTCGCGCGCGAGATTGCCTGCACGGCGGACGATGGC
CGTATCGTGCTGATCGCGCTGCTGGGCGGCGCCAAGGCCGAGGTGCCGCTGGGCGAGATCCTGCGCAGGCGCATCACGCT
GACGGGCTCGACGCTGCGGCCCCGTCCCGTGGCGTTCAAGGCGGCGATCGCCGCTCACCTGCATGACACGGTGTGGCCGC
TGCTGGCTTCCGGTCGCATCCGGCCGGTCATCCACGAGGTGATGCCCGCGGAGCATGCCGCGCAGGCGCACGCGCTGATG
GAATCGAGTGCGCACATCGGCAAGATCATGCTGACCTGGGGCTAG

Upstream 100 bases:

>100_bases
TCCACGGCAAGCAGGAGATCCTGCGCGAGACCACGCGCGGCATCCCGCAGCATTTTGTCGAGCCCAAGCGCAGCGCATCG
TAATCCCGATCCCGAATGCC

Downstream 100 bases:

>100_bases
CGCACGCATGCGGTCGCGTCCGGGCGACAAAATTGACCCCGTTTTTGCCGCCACGGTAGAATGCCGGGTTTATTTGACTG
TCGACTTGGCGGAACAACAA

Product: NADPH quinone oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MRAIEITQYGGPDVLKPAERPMPEPKAGEVLIRVRAAGVNRPDVFQRTGNYPVPPGASDIPGLEVAGEIVGGDLAHADNR
YGLRAGDRVCALVQGGGYAEFCTAPLGQVLPVPAGLSDIEAAALPENYFTVWSNVFDRGQLGQGAHGKGETLLVQGGSSG
IGTTAIQMASALGYRVFATAGSDEKCAACVALGAARAIRYRTEDFAEVVKAETGRGVDVVLDMVGGSYVAREIACTADDG
RIVLIALLGGAKAEVPLGEILRRRITLTGSTLRPRPVAFKAAIAAHLHDTVWPLLASGRIRPVIHEVMPAEHAAQAHALM
ESSAHIGKIMLTWG

Sequences:

>Translated_334_residues
MRAIEITQYGGPDVLKPAERPMPEPKAGEVLIRVRAAGVNRPDVFQRTGNYPVPPGASDIPGLEVAGEIVGGDLAHADNR
YGLRAGDRVCALVQGGGYAEFCTAPLGQVLPVPAGLSDIEAAALPENYFTVWSNVFDRGQLGQGAHGKGETLLVQGGSSG
IGTTAIQMASALGYRVFATAGSDEKCAACVALGAARAIRYRTEDFAEVVKAETGRGVDVVLDMVGGSYVAREIACTADDG
RIVLIALLGGAKAEVPLGEILRRRITLTGSTLRPRPVAFKAAIAAHLHDTVWPLLASGRIRPVIHEVMPAEHAAQAHALM
ESSAHIGKIMLTWG
>Mature_334_residues
MRAIEITQYGGPDVLKPAERPMPEPKAGEVLIRVRAAGVNRPDVFQRTGNYPVPPGASDIPGLEVAGEIVGGDLAHADNR
YGLRAGDRVCALVQGGGYAEFCTAPLGQVLPVPAGLSDIEAAALPENYFTVWSNVFDRGQLGQGAHGKGETLLVQGGSSG
IGTTAIQMASALGYRVFATAGSDEKCAACVALGAARAIRYRTEDFAEVVKAETGRGVDVVLDMVGGSYVAREIACTADDG
RIVLIALLGGAKAEVPLGEILRRRITLTGSTLRPRPVAFKAAIAAHLHDTVWPLLASGRIRPVIHEVMPAEHAAQAHALM
ESSAHIGKIMLTWG

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=339, Percent_Identity=37.1681415929204, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI22538444, Length=339, Percent_Identity=37.1681415929204, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI194239674, Length=335, Percent_Identity=29.8507462686567, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI13236495, Length=335, Percent_Identity=29.8507462686567, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI18379349, Length=354, Percent_Identity=31.0734463276836, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI24308257, Length=351, Percent_Identity=27.3504273504274, Blast_Score=118, Evalue=7e-27,
Organism=Homo sapiens, GI194239676, Length=334, Percent_Identity=29.0419161676647, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI28557745, Length=281, Percent_Identity=29.5373665480427, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI41872631, Length=315, Percent_Identity=30.1587301587302, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI47519420, Length=358, Percent_Identity=27.6536312849162, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI197927207, Length=189, Percent_Identity=25.3968253968254, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1790485, Length=339, Percent_Identity=30.6784660766962, Blast_Score=108, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17507255, Length=337, Percent_Identity=26.4094955489614, Blast_Score=100, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6319520, Length=338, Percent_Identity=26.9230769230769, Blast_Score=90, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6323961, Length=300, Percent_Identity=25.3333333333333, Blast_Score=73, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6324486, Length=291, Percent_Identity=24.0549828178694, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221330659, Length=279, Percent_Identity=29.0322580645161, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI19920632, Length=279, Percent_Identity=29.0322580645161, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24581345, Length=271, Percent_Identity=28.7822878228782, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI45550423, Length=321, Percent_Identity=24.9221183800623, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34970; Mature: 34970

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS00962 RIBOSOMAL_S2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAIEITQYGGPDVLKPAERPMPEPKAGEVLIRVRAAGVNRPDVFQRTGNYPVPPGASDI
CCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHCCCCCCCCCCCCC
PGLEVAGEIVGGDLAHADNRYGLRAGDRVCALVQGGGYAEFCTAPLGQVLPVPAGLSDIE
CCHHHHHHHHCCCHHCCCCCCCCCCCCEEEEEEECCCCHHHHHCCCHHHCCCCCCCCHHH
AAALPENYFTVWSNVFDRGQLGQGAHGKGETLLVQGGSSGIGTTAIQMASALGYRVFATA
HHHCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCEEEEEEC
GSDEKCAACVALGAARAIRYRTEDFAEVVKAETGRGVDVVLDMVGGSYVAREIACTADDG
CCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCEEEEEHHCCHHHHHEEEEECCCC
RIVLIALLGGAKAEVPLGEILRRRITLTGSTLRPRPVAFKAAIAAHLHDTVWPLLASGRI
CEEEEEEECCCCCCCCHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
RPVIHEVMPAEHAAQAHALMESSAHIGKIMLTWG
HHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECC
>Mature Secondary Structure
MRAIEITQYGGPDVLKPAERPMPEPKAGEVLIRVRAAGVNRPDVFQRTGNYPVPPGASDI
CCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHCCCCCCCCCCCCC
PGLEVAGEIVGGDLAHADNRYGLRAGDRVCALVQGGGYAEFCTAPLGQVLPVPAGLSDIE
CCHHHHHHHHCCCHHCCCCCCCCCCCCEEEEEEECCCCHHHHHCCCHHHCCCCCCCCHHH
AAALPENYFTVWSNVFDRGQLGQGAHGKGETLLVQGGSSGIGTTAIQMASALGYRVFATA
HHHCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCEEEEEEC
GSDEKCAACVALGAARAIRYRTEDFAEVVKAETGRGVDVVLDMVGGSYVAREIACTADDG
CCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCEEEEEHHCCHHHHHEEEEECCCC
RIVLIALLGGAKAEVPLGEILRRRITLTGSTLRPRPVAFKAAIAAHLHDTVWPLLASGRI
CEEEEEEECCCCCCCCHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
RPVIHEVMPAEHAAQAHALMESSAHIGKIMLTWG
HHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]