Click here to switch to the map view.

The map label for this gene is nuoH [H]

Identifier: 17546774

GI number: 17546774

Start: 2227878

End: 2228942

Strand: Reverse

Name: nuoH [H]

Synonym: RSc2055

Alternate gene names: 17546774

Gene position: 2228942-2227878 (Counterclockwise)

Preceding gene: 17546775

Following gene: 17546773

Centisome position: 59.98

GC content: 62.07

Gene sequence:

>1065_bases
ATGATCGAGTCGATTACCTCTTTCGGCGCGGCGACCTTCGGCGGCTGGTGGCCGCTGATCTGGACGCTGGTGCGTGCCGT
TTGCATCATCCTGCCGCTGCTGCTGTGCGTGGCTTACCTGATCCTGTGGGAGCGCAAGCTGATCGGCTGGATGCACGTGC
GGGTGGGTCCGAACCGCGTGGGCCCGATGGGCCTGCTGCAGCCGATCGCCGACGTGCTCAAGCTGCTGCTCAAGGAAGTC
ATGGTGCCGAGCGCGGTCAGCCGTGGCATGTACATCATCGCGCCGCTGATGGTGCTGATGCCGGCCGTGGCGATCTGGGC
GGTGGTGCCGTTCCAGGCCGAGGCTGTGGTGTCGAACATCAATGCCGGCCTGCTGTACGTGATGGCGATCAGTTCGGTGG
GCGTGTACGGCGTGATCCTGGCCGGCTGGGCCTCGAACTCCAAGTACGCGTTCCTGGGCGCGATGCGCGCCTCGGCACAG
ATGATCTCGTACGAAATCGCCATGGGCTTCGCGCTCGTGACGGTGCTGATGGTCACCGGCAGCCTGAACCTGTCGGACAT
CGTCAATTCGCAGAACCGCGGCTTCTTCGCCAACCACGGCATCAACATCCTGTCGTGGAACTGGCTGTCGCTGCTGCCGA
TGTTCGGCGTGTATTTCATCTCGGGCGTGGCCGAAACCAACCGCCACCCGTTCGACGTGGTGGAAGGCGAATCGGAAATC
GTGGCCGGCCACATGATCGAATACTCGGGCATGGCGTTCGCGCTGTTCTTCCTGGCCGAGTACATCAACATGATCGTCAT
CTCGGCGATGACGGCGACGATGTTCCTGGGCGGCTGGTCCGCGCCGATCGATGCGCCGGTGTTCAACTGGATTCCGGGCT
TCTTCTGGTTGCTGATCAAGGTCTTCCTGTTGCTGTCGGTCTTCATCTGGCTGCGTGCGTCGTTCCCGCGCTACCGCTAT
GACCAGATCATGCGCCTGGGCTGGAAGATCTTCATTCCGCTCACCGTGGGTTGGCTGATCATCGTTGCCATCTGGCTGGT
GTCGCCGTGGAACATCTGGAAGTAA

Upstream 100 bases:

>100_bases
CCGCGACCGAGGCATCGGCGCAACTGGGCCCGATGTTCGGTACGGTGAGCGTTGAAAAGGCCGAATCTTCCGCGCTGGCG
GCTACGGTGTAAGGATCAAC

Downstream 100 bases:

>100_bases
CGGGACAATAGGAAGGCACCATGTTGCTTGCCATCAAGGAATTCTTTAACAGCCTGCTCCTGAAGGAACTCTTCAAGGGG
CTGGCGCTGACCGGGCGCTA

Product: NADH dehydrogenase subunit H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MIESITSFGAATFGGWWPLIWTLVRAVCIILPLLLCVAYLILWERKLIGWMHVRVGPNRVGPMGLLQPIADVLKLLLKEV
MVPSAVSRGMYIIAPLMVLMPAVAIWAVVPFQAEAVVSNINAGLLYVMAISSVGVYGVILAGWASNSKYAFLGAMRASAQ
MISYEIAMGFALVTVLMVTGSLNLSDIVNSQNRGFFANHGINILSWNWLSLLPMFGVYFISGVAETNRHPFDVVEGESEI
VAGHMIEYSGMAFALFFLAEYINMIVISAMTATMFLGGWSAPIDAPVFNWIPGFFWLLIKVFLLLSVFIWLRASFPRYRY
DQIMRLGWKIFIPLTVGWLIIVAIWLVSPWNIWK

Sequences:

>Translated_354_residues
MIESITSFGAATFGGWWPLIWTLVRAVCIILPLLLCVAYLILWERKLIGWMHVRVGPNRVGPMGLLQPIADVLKLLLKEV
MVPSAVSRGMYIIAPLMVLMPAVAIWAVVPFQAEAVVSNINAGLLYVMAISSVGVYGVILAGWASNSKYAFLGAMRASAQ
MISYEIAMGFALVTVLMVTGSLNLSDIVNSQNRGFFANHGINILSWNWLSLLPMFGVYFISGVAETNRHPFDVVEGESEI
VAGHMIEYSGMAFALFFLAEYINMIVISAMTATMFLGGWSAPIDAPVFNWIPGFFWLLIKVFLLLSVFIWLRASFPRYRY
DQIMRLGWKIFIPLTVGWLIIVAIWLVSPWNIWK
>Mature_354_residues
MIESITSFGAATFGGWWPLIWTLVRAVCIILPLLLCVAYLILWERKLIGWMHVRVGPNRVGPMGLLQPIADVLKLLLKEV
MVPSAVSRGMYIIAPLMVLMPAVAIWAVVPFQAEAVVSNINAGLLYVMAISSVGVYGVILAGWASNSKYAFLGAMRASAQ
MISYEIAMGFALVTVLMVTGSLNLSDIVNSQNRGFFANHGINILSWNWLSLLPMFGVYFISGVAETNRHPFDVVEGESEI
VAGHMIEYSGMAFALFFLAEYINMIVISAMTATMFLGGWSAPIDAPVFNWIPGFFWLLIKVFLLLSVFIWLRASFPRYRY
DQIMRLGWKIFIPLTVGWLIIVAIWLVSPWNIWK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=305, Percent_Identity=43.6065573770492, Blast_Score=255, Evalue=4e-68,
Organism=Escherichia coli, GI1788618, Length=322, Percent_Identity=41.9254658385093, Blast_Score=260, Evalue=1e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 39512; Mature: 39512

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIESITSFGAATFGGWWPLIWTLVRAVCIILPLLLCVAYLILWERKLIGWMHVRVGPNRV
CCCCHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCC
GPMGLLQPIADVLKLLLKEVMVPSAVSRGMYIIAPLMVLMPAVAIWAVVPFQAEAVVSNI
CCHHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHC
NAGLLYVMAISSVGVYGVILAGWASNSKYAFLGAMRASAQMISYEIAMGFALVTVLMVTG
CCHHHHHHHHHHCCHHHHHHEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SLNLSDIVNSQNRGFFANHGINILSWNWLSLLPMFGVYFISGVAETNRHPFDVVEGESEI
CCCHHHHHCCCCCCEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCHH
VAGHMIEYSGMAFALFFLAEYINMIVISAMTATMFLGGWSAPIDAPVFNWIPGFFWLLIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
VFLLLSVFIWLRASFPRYRYDQIMRLGWKIFIPLTVGWLIIVAIWLVSPWNIWK
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHEEHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MIESITSFGAATFGGWWPLIWTLVRAVCIILPLLLCVAYLILWERKLIGWMHVRVGPNRV
CCCCHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCC
GPMGLLQPIADVLKLLLKEVMVPSAVSRGMYIIAPLMVLMPAVAIWAVVPFQAEAVVSNI
CCHHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHC
NAGLLYVMAISSVGVYGVILAGWASNSKYAFLGAMRASAQMISYEIAMGFALVTVLMVTG
CCHHHHHHHHHHCCHHHHHHEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SLNLSDIVNSQNRGFFANHGINILSWNWLSLLPMFGVYFISGVAETNRHPFDVVEGESEI
CCCHHHHHCCCCCCEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCHH
VAGHMIEYSGMAFALFFLAEYINMIVISAMTATMFLGGWSAPIDAPVFNWIPGFFWLLIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
VFLLLSVFIWLRASFPRYRYDQIMRLGWKIFIPLTVGWLIIVAIWLVSPWNIWK
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHEEHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA