Click here to switch to the map view.

The map label for this gene is nuoG [H]

Identifier: 17546775

GI number: 17546775

Start: 2228951

End: 2231302

Strand: Reverse

Name: nuoG [H]

Synonym: RSc2056

Alternate gene names: 17546775

Gene position: 2231302-2228951 (Counterclockwise)

Preceding gene: 17546776

Following gene: 17546774

Centisome position: 60.04

GC content: 67.6

Gene sequence:

>2352_bases
ATGGTTGAAATCGAAATCGATGGCAAGAAGGTCGAGGTTGCCGAAGGCAGCCTGGTGATGGAGGCCGCCCGTCAGGCGGG
CACCTATATCCCGCACTTCTGCTATCACCGCAAGCTGTCGATCGCGGCGAACTGCCGGATGTGCCTGGTCGAGGTCGAGA
AGGCGCCCAAGGCGCTGCCGGCCTGCGCCACGCCGGTTACCGCGGGCATGAAGGTCTTCACCAACTCCGAGAAGGCGGTG
AAGGCGCAGAAGTCCGTGATGGAGTTCCTGCTGATCAACCACCCGCTGGATTGCCCGATCTGCGATCAGGGCGGCGAATG
CCAGCTGCAGGATCTGGCCGTGGGCTACGGCAAGTCCGAATCGCGCTACAAGGAAGAGAAGCGCGTGGTGTTCCATAAGA
ACGTCGGCCCGCTGATCTCGATGGAAGAGATGACGCGCTGCATCCACTGCACGCGCTGCGTCCGCTTCGGCCAGGAAGTG
GCCGGCGTGATGGAGCTGGGCATGCTCAACCGCGGCGAGCATTCCGAGATCACCACGTTCGTCGGCCAGACCGTCGATTC
CGAGCTGTCGGGCAACATGATCGACCTGTGCCCGGTCGGCGCGCTGACCAGCAAGCCGTTCCGCTACTCGGCTCGCACGT
GGGAGCTGGCACGCCGCAAGTCGGTGTCGCCGCACGATGGCCTGGGCGCCAACGTGATCGTCCAGACCAAGAACCAGCGC
GTGATGCGCGTGCTGCCGCTGGAAAACGATGCCATCAACGAATGCTGGCTGTCCGACAAGGACCGCTTTGCCTATGAGGG
CCTCAACAGCGACGAGCGCCTGACCCAGCCGATGCTCAAGCAGGGCGGCCAATGGCAGACCGTGGACTGGACCACGGCGC
TGGAGTATGTCGCCAACGGCCTGAATGCGATCAAGCGCGACCACGGTGCCGAGCAGATCGGTGCGCTGGCCAGCCCGCAC
AGCACGCTGGAAGAGCTGTTCCTGTTGCAAAAGCTGGTGCGCGGCATCGGCAGCGACAGCGTCGACTTCCGCCTGCGCCA
ATCCGATTTCTCCGCCAAGCCGACGGGCGCACCGTGGCTGGGCATGCCGATCGCCGATGTGTCGCTGCTGCAGCGCACGC
TGGTGGTGGGCGCGTTCCTGCGCAAGGATCATCCGCTGCTGGCCGCGCGTCTGCGCCAGGGCGGCAAGAAGGGCGCGCAG
CTGAGCGTGATCGGCGCCGGCGGCGAAGACCTGCTGATGCCGGCGACGCAGCTGCTGGGTGCGCCGTCGCAGTGGCTGTC
GCTGCTGTCGGAAGTGGCCGTGGCGATCGCCGCCGCCAATAGCGTTGCCCGCCCGGTCGGTACCGATGGCATCGAGGCCG
GCGAAGTCGCCAAGCGCATCGCCGCGAGCCTGGCTTCGGGTGAGCGCAAGGCGGTGTTCCTGGGCAACGCTGCCGTGGCC
CATCCGCAGTTCTCCAAGCTGCATGCGCTGGCCCAGTGGGTCGCGCAGCAGACCGGCGCGACGCTGGGCTTCCTGACCGA
AGCCGCGAATACCGTCGGCGGCTACATCGCCGGTGCGCTGCCGCAAGGCAACGGTCTGGACGCTGCCGCCATGCTGGCGC
AGCCGCGGCGTGCCTACGTCATCCTGGGCGCCGAGCCGGAATTCGATTCGGCGAATCCGCAGCAGGCGCGTGCCGCGCTG
GCGCATGCCGACACCGTGGTGATGCTGTCGCCGTTCGCCTCGCGCGCCGCGATGGAACACGCCGACGTGCTGCTGCCGGT
TGCGCCGTTCACGGAAACCTCGGGCACCTACATCAACTGCGAAGGCCTGCCGCAAAGCTTCAACGGCGTGGTCCGCAGCC
TGGGCGATTCGCGTCCGGCATGGAAGGTGCTGCGCGTGCTGGGCAATCTGCTGGGCCTGTCGGGCTTCGAGTACGAAACG
TCGGAAGCCGTGCGTGACGACGTGCTGGCCAAGCCGGTCGCCGAGCGGCTGTCGAACGCCACCGCCGCGCAGACTGCTGC
ACCGGTTGCTGCCGCAGGCGGTATCGAGCGACTGGCCGACGTGCCGATCTACCATGCCGATCCGATCGTGCGCCGTGCCG
GTTCGCTGCAACTGACGGCCGCGTCCCGCGCCGCGGTGCGCGCCGGCCTGCCGGCCGACCTGTTCGAACAGCTGGGCCTG
GCCGTCGGTGACGCCGTGCGCGTCACGCAGGGGCAGGGCAGCGTGGTGCTGCCGGCGGTGCTGGACCGCACGCTGGCCTC
CGGCGTGATTCGCGTGCCGGCCGCGACCGAGGCATCGGCGCAACTGGGCCCGATGTTCGGTACGGTGAGCGTTGAAAAGG
CCGAATCTTCCGCGCTGGCGGCTACGGTGTAA

Upstream 100 bases:

>100_bases
GCCGGTCCGCGGCATGCTCAAGCACTACTGGGACGAGTTCGCGTATCACGTCGAGCACAAGCAGTGCATGGTGCCCACCT
ACATCTAAGCGTGGCAGAAC

Downstream 100 bases:

>100_bases
GGATCAACATGATCGAGTCGATTACCTCTTTCGGCGCGGCGACCTTCGGCGGCTGGTGGCCGCTGATCTGGACGCTGGTG
CGTGCCGTTTGCATCATCCT

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G; NDH-1 subunit G [H]

Number of amino acids: Translated: 783; Mature: 783

Protein sequence:

>783_residues
MVEIEIDGKKVEVAEGSLVMEAARQAGTYIPHFCYHRKLSIAANCRMCLVEVEKAPKALPACATPVTAGMKVFTNSEKAV
KAQKSVMEFLLINHPLDCPICDQGGECQLQDLAVGYGKSESRYKEEKRVVFHKNVGPLISMEEMTRCIHCTRCVRFGQEV
AGVMELGMLNRGEHSEITTFVGQTVDSELSGNMIDLCPVGALTSKPFRYSARTWELARRKSVSPHDGLGANVIVQTKNQR
VMRVLPLENDAINECWLSDKDRFAYEGLNSDERLTQPMLKQGGQWQTVDWTTALEYVANGLNAIKRDHGAEQIGALASPH
STLEELFLLQKLVRGIGSDSVDFRLRQSDFSAKPTGAPWLGMPIADVSLLQRTLVVGAFLRKDHPLLAARLRQGGKKGAQ
LSVIGAGGEDLLMPATQLLGAPSQWLSLLSEVAVAIAAANSVARPVGTDGIEAGEVAKRIAASLASGERKAVFLGNAAVA
HPQFSKLHALAQWVAQQTGATLGFLTEAANTVGGYIAGALPQGNGLDAAAMLAQPRRAYVILGAEPEFDSANPQQARAAL
AHADTVVMLSPFASRAAMEHADVLLPVAPFTETSGTYINCEGLPQSFNGVVRSLGDSRPAWKVLRVLGNLLGLSGFEYET
SEAVRDDVLAKPVAERLSNATAAQTAAPVAAAGGIERLADVPIYHADPIVRRAGSLQLTAASRAAVRAGLPADLFEQLGL
AVGDAVRVTQGQGSVVLPAVLDRTLASGVIRVPAATEASAQLGPMFGTVSVEKAESSALAATV

Sequences:

>Translated_783_residues
MVEIEIDGKKVEVAEGSLVMEAARQAGTYIPHFCYHRKLSIAANCRMCLVEVEKAPKALPACATPVTAGMKVFTNSEKAV
KAQKSVMEFLLINHPLDCPICDQGGECQLQDLAVGYGKSESRYKEEKRVVFHKNVGPLISMEEMTRCIHCTRCVRFGQEV
AGVMELGMLNRGEHSEITTFVGQTVDSELSGNMIDLCPVGALTSKPFRYSARTWELARRKSVSPHDGLGANVIVQTKNQR
VMRVLPLENDAINECWLSDKDRFAYEGLNSDERLTQPMLKQGGQWQTVDWTTALEYVANGLNAIKRDHGAEQIGALASPH
STLEELFLLQKLVRGIGSDSVDFRLRQSDFSAKPTGAPWLGMPIADVSLLQRTLVVGAFLRKDHPLLAARLRQGGKKGAQ
LSVIGAGGEDLLMPATQLLGAPSQWLSLLSEVAVAIAAANSVARPVGTDGIEAGEVAKRIAASLASGERKAVFLGNAAVA
HPQFSKLHALAQWVAQQTGATLGFLTEAANTVGGYIAGALPQGNGLDAAAMLAQPRRAYVILGAEPEFDSANPQQARAAL
AHADTVVMLSPFASRAAMEHADVLLPVAPFTETSGTYINCEGLPQSFNGVVRSLGDSRPAWKVLRVLGNLLGLSGFEYET
SEAVRDDVLAKPVAERLSNATAAQTAAPVAAAGGIERLADVPIYHADPIVRRAGSLQLTAASRAAVRAGLPADLFEQLGL
AVGDAVRVTQGQGSVVLPAVLDRTLASGVIRVPAATEASAQLGPMFGTVSVEKAESSALAATV
>Mature_783_residues
MVEIEIDGKKVEVAEGSLVMEAARQAGTYIPHFCYHRKLSIAANCRMCLVEVEKAPKALPACATPVTAGMKVFTNSEKAV
KAQKSVMEFLLINHPLDCPICDQGGECQLQDLAVGYGKSESRYKEEKRVVFHKNVGPLISMEEMTRCIHCTRCVRFGQEV
AGVMELGMLNRGEHSEITTFVGQTVDSELSGNMIDLCPVGALTSKPFRYSARTWELARRKSVSPHDGLGANVIVQTKNQR
VMRVLPLENDAINECWLSDKDRFAYEGLNSDERLTQPMLKQGGQWQTVDWTTALEYVANGLNAIKRDHGAEQIGALASPH
STLEELFLLQKLVRGIGSDSVDFRLRQSDFSAKPTGAPWLGMPIADVSLLQRTLVVGAFLRKDHPLLAARLRQGGKKGAQ
LSVIGAGGEDLLMPATQLLGAPSQWLSLLSEVAVAIAAANSVARPVGTDGIEAGEVAKRIAASLASGERKAVFLGNAAVA
HPQFSKLHALAQWVAQQTGATLGFLTEAANTVGGYIAGALPQGNGLDAAAMLAQPRRAYVILGAEPEFDSANPQQARAAL
AHADTVVMLSPFASRAAMEHADVLLPVAPFTETSGTYINCEGLPQSFNGVVRSLGDSRPAWKVLRVLGNLLGLSGFEYET
SEAVRDDVLAKPVAERLSNATAAQTAAPVAAAGGIERLADVPIYHADPIVRRAGSLQLTAASRAAVRAGLPADLFEQLGL
AVGDAVRVTQGQGSVVLPAVLDRTLASGVIRVPAATEASAQLGPMFGTVSVEKAESSALAATV

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=658, Percent_Identity=36.4741641337386, Blast_Score=389, Evalue=1e-108,
Organism=Escherichia coli, GI145693161, Length=344, Percent_Identity=32.8488372093023, Blast_Score=206, Evalue=5e-54,
Organism=Caenorhabditis elegans, GI17565758, Length=650, Percent_Identity=37.6923076923077, Blast_Score=365, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI32566231, Length=621, Percent_Identity=38.0032206119163, Blast_Score=350, Evalue=2e-96,
Organism=Caenorhabditis elegans, GI193209088, Length=254, Percent_Identity=51.5748031496063, Blast_Score=271, Evalue=9e-73,
Organism=Drosophila melanogaster, GI24640559, Length=688, Percent_Identity=36.7732558139535, Blast_Score=371, Evalue=1e-103,
Organism=Drosophila melanogaster, GI24640557, Length=688, Percent_Identity=36.7732558139535, Blast_Score=371, Evalue=1e-103,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574
- InterPro:   IPR015405 [H]

Pfam domain/function: PF09326 DUF1982; PF00111 Fer2; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 83198; Mature: 83198

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2 ; PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEIEIDGKKVEVAEGSLVMEAARQAGTYIPHFCYHRKLSIAANCRMCLVEVEKAPKALP
CEEEEECCCEEEECCCHHHHHHHHHCCCCCCHHHHHCCCEECCCCEEEEEEHHHCCCCCC
ACATPVTAGMKVFTNSEKAVKAQKSVMEFLLINHPLDCPICDQGGECQLQDLAVGYGKSE
CCCCCHHCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEHHEECCCCCH
SRYKEEKRVVFHKNVGPLISMEEMTRCIHCTRCVRFGQEVAGVMELGMLNRGEHSEITTF
HHHHHHHCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
VGQTVDSELSGNMIDLCPVGALTSKPFRYSARTWELARRKSVSPHDGLGANVIVQTKNQR
HHHHHHHHHCCCEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEEECCCC
VMRVLPLENDAINECWLSDKDRFAYEGLNSDERLTQPMLKQGGQWQTVDWTTALEYVANG
EEEEECCCCCCHHHHCCCCCCCHHCCCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHH
LNAIKRDHGAEQIGALASPHSTLEELFLLQKLVRGIGSDSVDFRLRQSDFSAKPTGAPWL
HHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCC
GMPIADVSLLQRTLVVGAFLRKDHPLLAARLRQGGKKGAQLSVIGAGGEDLLMPATQLLG
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHC
APSQWLSLLSEVAVAIAAANSVARPVGTDGIEAGEVAKRIAASLASGERKAVFLGNAAVA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCEEC
HPQFSKLHALAQWVAQQTGATLGFLTEAANTVGGYIAGALPQGNGLDAAAMLAQPRRAYV
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHEECCCCCCCCCHHHHHCCCCEEEE
ILGAEPEFDSANPQQARAALAHADTVVMLSPFASRAAMEHADVLLPVAPFTETSGTYINC
EEECCCCCCCCCHHHHHHHHHHCCEEEEECCHHHHHHHHHCCEEEECCCCCCCCCCEEEE
EGLPQSFNGVVRSLGDSRPAWKVLRVLGNLLGLSGFEYETSEAVRDDVLAKPVAERLSNA
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
TAAQTAAPVAAAGGIERLADVPIYHADPIVRRAGSLQLTAASRAAVRAGLPADLFEQLGL
HHHHHHCCHHHHCCHHHHHCCCCCCCCHHHHCCCCEEEEHHHHHHHHCCCCHHHHHHHCH
AVGDAVRVTQGQGSVVLPAVLDRTLASGVIRVPAATEASAQLGPMFGTVSVEKAESSALA
HHCCEEEEECCCCCEEHHHHHHHHHHCCEEECCCCCCCCHHHCCCEEEEEEECCCCCCCC
ATV
CCC
>Mature Secondary Structure
MVEIEIDGKKVEVAEGSLVMEAARQAGTYIPHFCYHRKLSIAANCRMCLVEVEKAPKALP
CEEEEECCCEEEECCCHHHHHHHHHCCCCCCHHHHHCCCEECCCCEEEEEEHHHCCCCCC
ACATPVTAGMKVFTNSEKAVKAQKSVMEFLLINHPLDCPICDQGGECQLQDLAVGYGKSE
CCCCCHHCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEHHEECCCCCH
SRYKEEKRVVFHKNVGPLISMEEMTRCIHCTRCVRFGQEVAGVMELGMLNRGEHSEITTF
HHHHHHHCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
VGQTVDSELSGNMIDLCPVGALTSKPFRYSARTWELARRKSVSPHDGLGANVIVQTKNQR
HHHHHHHHHCCCEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEEECCCC
VMRVLPLENDAINECWLSDKDRFAYEGLNSDERLTQPMLKQGGQWQTVDWTTALEYVANG
EEEEECCCCCCHHHHCCCCCCCHHCCCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHH
LNAIKRDHGAEQIGALASPHSTLEELFLLQKLVRGIGSDSVDFRLRQSDFSAKPTGAPWL
HHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCC
GMPIADVSLLQRTLVVGAFLRKDHPLLAARLRQGGKKGAQLSVIGAGGEDLLMPATQLLG
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHC
APSQWLSLLSEVAVAIAAANSVARPVGTDGIEAGEVAKRIAASLASGERKAVFLGNAAVA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCEEC
HPQFSKLHALAQWVAQQTGATLGFLTEAANTVGGYIAGALPQGNGLDAAAMLAQPRRAYV
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHEECCCCCCCCCHHHHHCCCCEEEE
ILGAEPEFDSANPQQARAALAHADTVVMLSPFASRAAMEHADVLLPVAPFTETSGTYINC
EEECCCCCCCCCHHHHHHHHHHCCEEEEECCHHHHHHHHHCCEEEECCCCCCCCCCEEEE
EGLPQSFNGVVRSLGDSRPAWKVLRVLGNLLGLSGFEYETSEAVRDDVLAKPVAERLSNA
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
TAAQTAAPVAAAGGIERLADVPIYHADPIVRRAGSLQLTAASRAAVRAGLPADLFEQLGL
HHHHHHCCHHHHCCHHHHHCCCCCCCCHHHHCCCCEEEEHHHHHHHHCCCCHHHHHHHCH
AVGDAVRVTQGQGSVVLPAVLDRTLASGVIRVPAATEASAQLGPMFGTVSVEKAESSALA
HHCCEEEEECCCCCEEHHHHHHHHHHCCEEECCCCCCCCHHHCCCEEEEEEECCCCCCCC
ATV
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA