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The map label for this gene is braD [H]

Identifier: 17546759

GI number: 17546759

Start: 2212860

End: 2214476

Strand: Reverse

Name: braD [H]

Synonym: RSc2040

Alternate gene names: 17546759

Gene position: 2214476-2212860 (Counterclockwise)

Preceding gene: 17546760

Following gene: 17546758

Centisome position: 59.59

GC content: 69.39

Gene sequence:

>1617_bases
ATGGCCATGACACGCTTCCTCGCCGCACTGCTGTGCGCCCTCTGCCTGGTTGCCACGCCTGCCGCATCGGCATGGGCGGC
CGGACAACCGCTGACCCAGGCCGATCTCAAGCCGCTGGCCGAAGACGACTTCGACGCCAAGGTGAAGGTGCTCAACGCCC
TGGCCGCCGCGCCCGCCGAACAGGCCGGCCCCATCCTGCGGGCGTTGCAGAATGATGCGCTGTTCTATGCGCCCGCTGCC
GGCATGCTGCGCCAGGAGGGCGAGCGTTATCTCGATGCGATCAGCGGCCAGCCGGTTGCCATGAAGGCCGATGACCTGCA
AGCGCTGACGCTGAACAATGCCCTGCGCGCCCAGGTGGACAGCGCGGCCAGCGGCTTCGTGCTGCAGTCGCCCGACCGGG
CCGTGCGCGCGCAGGCCATCGATACGCTGCTGGCGCATCCCGAGACGGCATCGCGCACGGTGGTCGATGCGGCGCGCAAG
CAGGAGACCGATCCCGAACTGCGGACCCGCCTGCATCTGCTGTGGGCCAACCTGGCGCTCGACGACGGCTCGCCTGCCGA
GAAGCTCGAAGCGCTCAGGCTGCTCGCCGGCGATACCAACCCGCAGACCCGCCAGCGCATCGCGCCGCTGCTCGCCAAGG
ACAGCGGCGCCGACGACGTGCTGCGCGCCGCTGCCCGGCAGGCGCTGGACAACCTTGCCGCGCAGGCGCGCAAGGCCGAG
CTGATCGGCAACCTGTTCGCCGGCCTGAGCCTGGGCTCGGTGCTGTTGCTGGCCGCGCTGGGGCTGGCGATCACCTACGG
CCTGATCGGCGTCATCAACATGGCGCACGGTGAGTTCCTGATGATCGGCGCGTATGCCACCTATGTGGTGCAGACGCTTT
TTCGCAACCATTTCCCTGCGGCGTTCGACTGGTATCTGCCCGCCGCGCTGCCGGCCGCGTTCCTGGCCGCGGCCGTCGTC
GGCTTCGTGCTGGAGCGCATGGTGCTGCGGCACCTGTACGGCCGGCCGCTGGAGACGCTGCTCGCCACCTTCGGCGTCAG
CCTGCTGCTGATGCAGGCCGTGCGCAGCGTGTTCGGTGCGCAGAACGTGGAGGTGGCCAACCCGAGCTGGATGAGCGGCG
GCATCGCGCTGTATCCGGGGCTGATCCTGCCGTATAACCGGCTGGTGATCCTGGCCTTCGCGCTGGTGGTGGTCACGCTG
GCGTGGGCGGTGCTCAACCGCACGCGGCTGGGCCTGTTCGTGCGCGCCACCACGCAGAACCGCGCCATGGCGGCGTGCGT
GGGCGTGCGGACCTGGAAGGTGGACAGCTACGCCTTCGCGTTCGGCGCGGGCATCGCCGGCCTGGGCGGCTGCGCGCTGT
CGCAGATCGGCAATGTGGGGCCGGACCTCGGGCAGGGCTACATCATCGATTCCTTCATGGCGGTGGTGCTGGGCGGGGTG
GGGCAGCTGGCCGGCACCATCGTCGGCGCGTTCGGGCTGGGGCTGATCAACAAGTGCATCGAGCCGTTCTATGGCGCGGT
GCTGGCGAAGATCTTCGTGCTGGTGCTGATCGTGCTGTTCATCCAGAAGCGTCCGCAGGGGCTGTTCGCCCTCAAGGGCC
GCAGCGCGGAGGCCTGA

Upstream 100 bases:

>100_bases
CGATCAGGTGATGTGACCGGGCGGACCGGCCCGCAGCGCCGGCCGGTCTCTTTTTCGACGTTGCATGGCGTGGCGGTCTG
CAAGGGCCGCCGCGTTCCGG

Downstream 100 bases:

>100_bases
CATGGCGCAGCCACCGTTCTCCCTCGACATTCCCGCGCGCATGCCGCTGCTGTCGCGGTGGGGCTGGTCCGTGCTGGCGG
CGGCGGCGCTGCTGGTCTGC

Product: ABC transporter permease

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 538; Mature: 537

Protein sequence:

>538_residues
MAMTRFLAALLCALCLVATPAASAWAAGQPLTQADLKPLAEDDFDAKVKVLNALAAAPAEQAGPILRALQNDALFYAPAA
GMLRQEGERYLDAISGQPVAMKADDLQALTLNNALRAQVDSAASGFVLQSPDRAVRAQAIDTLLAHPETASRTVVDAARK
QETDPELRTRLHLLWANLALDDGSPAEKLEALRLLAGDTNPQTRQRIAPLLAKDSGADDVLRAAARQALDNLAAQARKAE
LIGNLFAGLSLGSVLLLAALGLAITYGLIGVINMAHGEFLMIGAYATYVVQTLFRNHFPAAFDWYLPAALPAAFLAAAVV
GFVLERMVLRHLYGRPLETLLATFGVSLLLMQAVRSVFGAQNVEVANPSWMSGGIALYPGLILPYNRLVILAFALVVVTL
AWAVLNRTRLGLFVRATTQNRAMAACVGVRTWKVDSYAFAFGAGIAGLGGCALSQIGNVGPDLGQGYIIDSFMAVVLGGV
GQLAGTIVGAFGLGLINKCIEPFYGAVLAKIFVLVLIVLFIQKRPQGLFALKGRSAEA

Sequences:

>Translated_538_residues
MAMTRFLAALLCALCLVATPAASAWAAGQPLTQADLKPLAEDDFDAKVKVLNALAAAPAEQAGPILRALQNDALFYAPAA
GMLRQEGERYLDAISGQPVAMKADDLQALTLNNALRAQVDSAASGFVLQSPDRAVRAQAIDTLLAHPETASRTVVDAARK
QETDPELRTRLHLLWANLALDDGSPAEKLEALRLLAGDTNPQTRQRIAPLLAKDSGADDVLRAAARQALDNLAAQARKAE
LIGNLFAGLSLGSVLLLAALGLAITYGLIGVINMAHGEFLMIGAYATYVVQTLFRNHFPAAFDWYLPAALPAAFLAAAVV
GFVLERMVLRHLYGRPLETLLATFGVSLLLMQAVRSVFGAQNVEVANPSWMSGGIALYPGLILPYNRLVILAFALVVVTL
AWAVLNRTRLGLFVRATTQNRAMAACVGVRTWKVDSYAFAFGAGIAGLGGCALSQIGNVGPDLGQGYIIDSFMAVVLGGV
GQLAGTIVGAFGLGLINKCIEPFYGAVLAKIFVLVLIVLFIQKRPQGLFALKGRSAEA
>Mature_537_residues
AMTRFLAALLCALCLVATPAASAWAAGQPLTQADLKPLAEDDFDAKVKVLNALAAAPAEQAGPILRALQNDALFYAPAAG
MLRQEGERYLDAISGQPVAMKADDLQALTLNNALRAQVDSAASGFVLQSPDRAVRAQAIDTLLAHPETASRTVVDAARKQ
ETDPELRTRLHLLWANLALDDGSPAEKLEALRLLAGDTNPQTRQRIAPLLAKDSGADDVLRAAARQALDNLAAQARKAEL
IGNLFAGLSLGSVLLLAALGLAITYGLIGVINMAHGEFLMIGAYATYVVQTLFRNHFPAAFDWYLPAALPAAFLAAAVVG
FVLERMVLRHLYGRPLETLLATFGVSLLLMQAVRSVFGAQNVEVANPSWMSGGIALYPGLILPYNRLVILAFALVVVTLA
WAVLNRTRLGLFVRATTQNRAMAACVGVRTWKVDSYAFAFGAGIAGLGGCALSQIGNVGPDLGQGYIIDSFMAVVLGGVG
QLAGTIVGAFGLGLINKCIEPFYGAVLAKIFVLVLIVLFIQKRPQGLFALKGRSAEA

Specific function: Component of the high affinity leucine, isoleucine, valine, transport system (LIV-I), which is operative without Na(+) and is specific for alanine and threonine, in addition to branched-chain amino acids [H]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789866, Length=292, Percent_Identity=27.7397260273973, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 56865; Mature: 56734

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMTRFLAALLCALCLVATPAASAWAAGQPLTQADLKPLAEDDFDAKVKVLNALAAAPAE
CCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHCCCH
QAGPILRALQNDALFYAPAAGMLRQEGERYLDAISGQPVAMKADDLQALTLNNALRAQVD
HHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHH
SAASGFVLQSPDRAVRAQAIDTLLAHPETASRTVVDAARKQETDPELRTRLHLLWANLAL
HCCCCCEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
DDGSPAEKLEALRLLAGDTNPQTRQRIAPLLAKDSGADDVLRAAARQALDNLAAQARKAE
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LIGNLFAGLSLGSVLLLAALGLAITYGLIGVINMAHGEFLMIGAYATYVVQTLFRNHFPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCC
AFDWYLPAALPAAFLAAAVVGFVLERMVLRHLYGRPLETLLATFGVSLLLMQAVRSVFGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
QNVEVANPSWMSGGIALYPGLILPYNRLVILAFALVVVTLAWAVLNRTRLGLFVRATTQN
CCCEECCCCCCCCCHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCC
RAMAACVGVRTWKVDSYAFAFGAGIAGLGGCALSQIGNVGPDLGQGYIIDSFMAVVLGGV
CHHHHHHCCEEEEECCHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
GQLAGTIVGAFGLGLINKCIEPFYGAVLAKIFVLVLIVLFIQKRPQGLFALKGRSAEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCC
>Mature Secondary Structure 
AMTRFLAALLCALCLVATPAASAWAAGQPLTQADLKPLAEDDFDAKVKVLNALAAAPAE
CHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHCCCH
QAGPILRALQNDALFYAPAAGMLRQEGERYLDAISGQPVAMKADDLQALTLNNALRAQVD
HHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHH
SAASGFVLQSPDRAVRAQAIDTLLAHPETASRTVVDAARKQETDPELRTRLHLLWANLAL
HCCCCCEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
DDGSPAEKLEALRLLAGDTNPQTRQRIAPLLAKDSGADDVLRAAARQALDNLAAQARKAE
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LIGNLFAGLSLGSVLLLAALGLAITYGLIGVINMAHGEFLMIGAYATYVVQTLFRNHFPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCC
AFDWYLPAALPAAFLAAAVVGFVLERMVLRHLYGRPLETLLATFGVSLLLMQAVRSVFGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
QNVEVANPSWMSGGIALYPGLILPYNRLVILAFALVVVTLAWAVLNRTRLGLFVRATTQN
CCCEECCCCCCCCCHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCC
RAMAACVGVRTWKVDSYAFAFGAGIAGLGGCALSQIGNVGPDLGQGYIIDSFMAVVLGGV
CHHHHHHCCEEEEECCHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
GQLAGTIVGAFGLGLINKCIEPFYGAVLAKIFVLVLIVLFIQKRPQGLFALKGRSAEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2120183; 10984043; 2509433 [H]