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The map label for this gene is livM [C]

Identifier: 17546758

GI number: 17546758

Start: 2211668

End: 2212858

Strand: Reverse

Name: livM [C]

Synonym: RSc2039

Alternate gene names: 17546758

Gene position: 2212858-2211668 (Counterclockwise)

Preceding gene: 17546759

Following gene: 17546757

Centisome position: 59.54

GC content: 69.19

Gene sequence:

>1191_bases
ATGGCGCAGCCACCGTTCTCCCTCGACATTCCCGCGCGCATGCCGCTGCTGTCGCGGTGGGGCTGGTCCGTGCTGGCGGC
GGCGGCGCTGCTGGTCTGCGTCGGCGTGCCGGTGTGCGCGCTGGCGGTGCCGGCGGGGCATCCGCTGCACCTGTCGGCCT
ATGCGCTCACGCTGGTGGGCAAGATCATGTGCTACGCGCTGGCCGCGCTGGCGCTCGACCTGGTGTGGGGCTACTGCGGC
ATCCTGAGCCTCGGCCACGGCCTGTTCTTCGCGCTCGGCGGCTATGCGATGGGGATGTACCTGATGCGCGCCATCGGCCG
CGACGGTGTGTACCAGAGCGATCTGCCCGATTTCATGGTCTTCCTCGACTGGAAGGAACTGCCCTGGTTCTGGCACGGCA
CCGGGCATTTCGCCTGGGCCGCGCTGCTGGTGGTGCTGGTGCCGGGCGTGCTGGCGTGGCTGTTCGGCTTCTTCGCGTTC
CGCTCGCGGGTCAAGGGCGTGTACCTGTCGATCATCACGCAGGCCATGACCTACGCGGCCATGCTGCTGTTCTTCCGCAA
CGAAACGGGCTTCGGCGGCAACAACGGCTTCACCGATTTCAAGCGCATCCTCGGATACCCGATTGCAGCGGTGTCCACGC
GCACGGTGCTGTTCGTCGCCACCTTCATCGCGCTGGTGCTGGCCTTCATCGCATGCCGGGCCATCGTCACCTCCAAGTTC
GGGCGCGTGGTGACGGCCATCCGCGACGCCGAGGCGCGCGTGATGTTCTCCGGCTACAGCCCGCTCGGCTACAAGCTGTT
CGTGTGGACCTTCTCGGCCGTGCTGTGCGGTATCGCCGGGGCGCTGTACGTGCCGCAGGTCGGCATCATCAACCCGAGCG
AGATGTCGCCGGGCAACTCGATCGAGATGGCGGTGTGGGTGGCCGTGGGCGGGCGCGGCACGCTGGTTGGCCCGATCGTC
GGCGCGTTCCTCGTCAATGGCGCCAAGACCGTCCTGACGGCCTGGGTGCCGGAGTACTGGCTGTTCGTGCTGGGCGCGGT
CTTCGTGCTGGTGACCCTGTTCCTGCCGAACGGCGTGCTGGGCCTGCTGCGTGGCCGCTCCGGGCGGCGCGTGCGGCCGG
CGGCCGATGGCCGTGCGGATGCCGGCGCCGGCGAGCCCGTTGTCACCCCGCCCGCCGGAGACCGCGCATGA

Upstream 100 bases:

>100_bases
GTGCTGGCGAAGATCTTCGTGCTGGTGCTGATCGTGCTGTTCATCCAGAAGCGTCCGCAGGGGCTGTTCGCCCTCAAGGG
CCGCAGCGCGGAGGCCTGAC

Downstream 100 bases:

>100_bases
GGCCCTTCACCGCACGCCCCGACCGCGCGCAGGTCGGAAACTTCAGCGGCACCACCACCGGCATGGGCCACGTGCTCGAG
CCGGACGCCATCGACGTCTC

Product: ABC transporter permease

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: Urea ABC Transporter Permease Protein UrtC; Branched-Chain Amino Acid ABC Transporter Permease Protein; ABC Transporter Permease Protein; Urea ABC Transporter Permease UrtC; Amino Acid Or Sugar ABC Transport System Permease Protein; Branched Chain Amino Acid ABC Transporter Permease; Branched-Chain Amino Acid Transport System Permease Protein; Branched-Chain Amino Acid ABC Transporter Permease; ABC Transporter Related Protein; ABC Transporter Permease; ABC Transporter ; ABC Transporter; Branched-Chain Amino Acid Transporter; Urea ABC Transporter Permease; Permease Of ABC Transporter; ABC Transporter Membrane Spanning Protein; Permease Component Of ABC Transporter; Urea Or Short-Chain Amide ABC Transporter; Urea Or Short-Chain Amide ABC Transporter Permease Protein; Amide-Urea Transport System Permease Protein; Branched-Chain Amino Acid Inner-Membrane Translocator; Branched-Chain Amino Acid Transport Permease; Branched Chain Amino Acid ABC Transporter Permease Protein; Amide-Urea Transporter Permease Protein; Transmembrane Component Of ABC Transporter; High-Affinity Branched-Chain Amino Acid Transport System; Urea/Short Chain-Amide ABC Transporter Permease Protein; Urea ABC Transporter Permease Protein; ABC Transporter Membrane Protein; ABC-Type Urea Transport System Permease Protein II; Urea Transport System Permease Protein; ABC Transporter Inner-Membrane Translocator; ABC-Type Transport System Permease Protein; Integral Membrane Protein; Urea ABC Transporter Inner-Membrane Subunit UrtC; ABC Branched Amino Acid Transporter Permease Component; ABC-Type Branched-Chain Amino Acid Transport System; Branched-Chain Amino Acid Transport System Permease; Amino Acid/Amide ABC Transporter Membrane HAAT Family; Permease Protein Of ABC Transporter; Urea Transport System Permease Component Protein; Permease Transporter Transmembrane Protein; Urea ABC Transport Permease Component UrtC

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MAQPPFSLDIPARMPLLSRWGWSVLAAAALLVCVGVPVCALAVPAGHPLHLSAYALTLVGKIMCYALAALALDLVWGYCG
ILSLGHGLFFALGGYAMGMYLMRAIGRDGVYQSDLPDFMVFLDWKELPWFWHGTGHFAWAALLVVLVPGVLAWLFGFFAF
RSRVKGVYLSIITQAMTYAAMLLFFRNETGFGGNNGFTDFKRILGYPIAAVSTRTVLFVATFIALVLAFIACRAIVTSKF
GRVVTAIRDAEARVMFSGYSPLGYKLFVWTFSAVLCGIAGALYVPQVGIINPSEMSPGNSIEMAVWVAVGGRGTLVGPIV
GAFLVNGAKTVLTAWVPEYWLFVLGAVFVLVTLFLPNGVLGLLRGRSGRRVRPAADGRADAGAGEPVVTPPAGDRA

Sequences:

>Translated_396_residues
MAQPPFSLDIPARMPLLSRWGWSVLAAAALLVCVGVPVCALAVPAGHPLHLSAYALTLVGKIMCYALAALALDLVWGYCG
ILSLGHGLFFALGGYAMGMYLMRAIGRDGVYQSDLPDFMVFLDWKELPWFWHGTGHFAWAALLVVLVPGVLAWLFGFFAF
RSRVKGVYLSIITQAMTYAAMLLFFRNETGFGGNNGFTDFKRILGYPIAAVSTRTVLFVATFIALVLAFIACRAIVTSKF
GRVVTAIRDAEARVMFSGYSPLGYKLFVWTFSAVLCGIAGALYVPQVGIINPSEMSPGNSIEMAVWVAVGGRGTLVGPIV
GAFLVNGAKTVLTAWVPEYWLFVLGAVFVLVTLFLPNGVLGLLRGRSGRRVRPAADGRADAGAGEPVVTPPAGDRA
>Mature_395_residues
AQPPFSLDIPARMPLLSRWGWSVLAAAALLVCVGVPVCALAVPAGHPLHLSAYALTLVGKIMCYALAALALDLVWGYCGI
LSLGHGLFFALGGYAMGMYLMRAIGRDGVYQSDLPDFMVFLDWKELPWFWHGTGHFAWAALLVVLVPGVLAWLFGFFAFR
SRVKGVYLSIITQAMTYAAMLLFFRNETGFGGNNGFTDFKRILGYPIAAVSTRTVLFVATFIALVLAFIACRAIVTSKFG
RVVTAIRDAEARVMFSGYSPLGYKLFVWTFSAVLCGIAGALYVPQVGIINPSEMSPGNSIEMAVWVAVGGRGTLVGPIVG
AFLVNGAKTVLTAWVPEYWLFVLGAVFVLVTLFLPNGVLGLLRGRSGRRVRPAADGRADAGAGEPVVTPPAGDRA

Specific function: Part Of The Binding-Protein-Dependent Transport System For Branched-Chain Amino Acids. Probably Responsible For The Translocation Of The Substrates Across The Membrane. [C]

COG id: COG4177

COG function: function code E; ABC-type branched-chain amino acid transport system, permease component

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789865, Length=361, Percent_Identity=23.5457063711911, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 42428; Mature: 42297

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCC
>Mature Secondary Structure 
AQPPFSLDIPARMPLLSRWGWSVLAAAALLVCVGVPVCALAVPAGHPLHLSAYALTLVG
CCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
KIMCYALAALALDLVWGYCGILSLGHGLFFALGGYAMGMYLMRAIGRDGVYQSDLPDFMV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
FLDWKELPWFWHGTGHFAWAALLVVLVPGVLAWLFGFFAFRSRVKGVYLSIITQAMTYAA
EEEHHHCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLLFFRNETGFGGNNGFTDFKRILGYPIAAVSTRTVLFVATFIALVLAFIACRAIVTSKF
HHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRVVTAIRDAEARVMFSGYSPLGYKLFVWTFSAVLCGIAGALYVPQVGIINPSEMSPGNS
HHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
IEMAVWVAVGGRGTLVGPIVGAFLVNGAKTVLTAWVPEYWLFVLGAVFVLVTLFLPNGVL
EEEEEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
GLLRGRSGRRVRPAADGRADAGAGEPVVTPPAGDRA
HHHCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA