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The map label for this gene is paaG2 [H]

Identifier: 17546733

GI number: 17546733

Start: 2193272

End: 2194051

Strand: Direct

Name: paaG2 [H]

Synonym: RSc2014

Alternate gene names: 17546733

Gene position: 2193272-2194051 (Clockwise)

Preceding gene: 17546732

Following gene: 17546734

Centisome position: 59.02

GC content: 69.36

Gene sequence:

>780_bases
ATGACCGCGCAACTGCTCTCCCGACGCACCGGCTCCACGCTGGTGCTGACGCTCTCCAACCCCGACGCGCGCAACGCGCT
GGACCCGGTGATGTACACCGCGTCGATGGAGGCCCTCAACCTCGCCGCCAAGGACAAGGAGATCCGCAGCGTGATCTTCA
CCGGCGCGGACGGCGCCTTCTGCGCCGGCGGCAACCTCAACCGCCTGCTGGAGAACCGCAGCAAGCCCAAGCACGTGCAG
GAAGAAGGCATCGATGCGCTCAACCACTGGATCGAGACCATCCGCACCTTCCCCAAGCCGGTGATCGCGGCGGTGGAGGG
CCCGGCGGCGGGCGCGGGCTTCTCGCTGGTGCTGGCGTGCGATTTCGTGGTGGCCGCCGCGGATGCCAAGTTCGTGATGG
CCTACGTGAACGTGGCGCTGACGCCGGACGGCGGCGGCTCGTGGCACATCGCCCGCTTCCTGCCGCGCCCGCTGGCCAGC
GAGATCATCATGCTGGGCAAGCCTGTCAGCGCGGAGCGGCTCGCGCATTTCGGGCTGGTCAACGAGGTGGTCCGGCCCGG
CGCAGCCCTGGACCGCGCGCTGCTGCTGGCCGAGCAATTGGCCGCGCAGTCGCCGCACGCGGTCGGTCGCATCAAGGGGC
TGATCGCGCATGCGGAGGAGGCCTCGCTGCACGCGCACCTGCAGGCCGAGCAGCACAGCTTCGTCGAAGCGCTGCACCAC
GCCGACGGCAACGAAGGCATTTCGGCCTTCCTGCACAAGCGCCAACCCCAGTACCGCTGA

Upstream 100 bases:

>100_bases
CTATCGCCCAAGCCCATGGCTGCTGCGCCGCGCGCGCCTGGGCCTGTCGCTGCTGACGCCGGACGCCTGATCCGCCCCCC
CTTCCTCCGAGGCCATCGCC

Downstream 100 bases:

>100_bases
GGCGCCGCGCGATGGTCCCGTTTCCCGCCCCCAAGCGCCGCCGCATCTACCTGATGCGCCACGGCGCGGTCACGTACTTC
GACGCGACCGGCCGCCCCAT

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MTAQLLSRRTGSTLVLTLSNPDARNALDPVMYTASMEALNLAAKDKEIRSVIFTGADGAFCAGGNLNRLLENRSKPKHVQ
EEGIDALNHWIETIRTFPKPVIAAVEGPAAGAGFSLVLACDFVVAAADAKFVMAYVNVALTPDGGGSWHIARFLPRPLAS
EIIMLGKPVSAERLAHFGLVNEVVRPGAALDRALLLAEQLAAQSPHAVGRIKGLIAHAEEASLHAHLQAEQHSFVEALHH
ADGNEGISAFLHKRQPQYR

Sequences:

>Translated_259_residues
MTAQLLSRRTGSTLVLTLSNPDARNALDPVMYTASMEALNLAAKDKEIRSVIFTGADGAFCAGGNLNRLLENRSKPKHVQ
EEGIDALNHWIETIRTFPKPVIAAVEGPAAGAGFSLVLACDFVVAAADAKFVMAYVNVALTPDGGGSWHIARFLPRPLAS
EIIMLGKPVSAERLAHFGLVNEVVRPGAALDRALLLAEQLAAQSPHAVGRIKGLIAHAEEASLHAHLQAEQHSFVEALHH
ADGNEGISAFLHKRQPQYR
>Mature_258_residues
TAQLLSRRTGSTLVLTLSNPDARNALDPVMYTASMEALNLAAKDKEIRSVIFTGADGAFCAGGNLNRLLENRSKPKHVQE
EGIDALNHWIETIRTFPKPVIAAVEGPAAGAGFSLVLACDFVVAAADAKFVMAYVNVALTPDGGGSWHIARFLPRPLASE
IIMLGKPVSAERLAHFGLVNEVVRPGAALDRALLLAEQLAAQSPHAVGRIKGLIAHAEEASLHAHLQAEQHSFVEALHHA
DGNEGISAFLHKRQPQYR

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=245, Percent_Identity=28.5714285714286, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI31542718, Length=243, Percent_Identity=30.4526748971193, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI25453481, Length=255, Percent_Identity=23.921568627451, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI51538573, Length=255, Percent_Identity=23.921568627451, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI4757966, Length=212, Percent_Identity=26.4150943396226, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI51538581, Length=212, Percent_Identity=26.4150943396226, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI221136756, Length=258, Percent_Identity=24.4186046511628, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI221136753, Length=258, Percent_Identity=24.4186046511628, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI221307494, Length=258, Percent_Identity=24.4186046511628, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI4757968, Length=255, Percent_Identity=23.5294117647059, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI49355787, Length=255, Percent_Identity=23.5294117647059, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI4502327, Length=253, Percent_Identity=30.4347826086957, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI116235487, Length=212, Percent_Identity=27.3584905660377, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI70995211, Length=235, Percent_Identity=30.2127659574468, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI260274832, Length=244, Percent_Identity=27.4590163934426, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI45643119, Length=255, Percent_Identity=27.0588235294118, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI260275230, Length=255, Percent_Identity=27.0588235294118, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI20127408, Length=180, Percent_Identity=25.5555555555556, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI68989263, Length=189, Percent_Identity=28.042328042328, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI157694516, Length=223, Percent_Identity=23.7668161434978, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI213417737, Length=223, Percent_Identity=23.7668161434978, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787659, Length=264, Percent_Identity=33.7121212121212, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1787660, Length=259, Percent_Identity=37.0656370656371, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI221142681, Length=265, Percent_Identity=33.2075471698113, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1788597, Length=256, Percent_Identity=31.640625, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI87082183, Length=241, Percent_Identity=27.8008298755187, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1790281, Length=170, Percent_Identity=28.2352941176471, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788682, Length=202, Percent_Identity=28.7128712871287, Blast_Score=67, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17554946, Length=244, Percent_Identity=30.327868852459, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI25145438, Length=253, Percent_Identity=31.6205533596838, Blast_Score=117, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17540714, Length=236, Percent_Identity=27.9661016949153, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17540306, Length=250, Percent_Identity=30.4, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17560910, Length=198, Percent_Identity=27.2727272727273, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17535521, Length=252, Percent_Identity=24.6031746031746, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17536985, Length=256, Percent_Identity=24.21875, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17549921, Length=189, Percent_Identity=28.042328042328, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17558304, Length=237, Percent_Identity=21.0970464135021, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI20129971, Length=244, Percent_Identity=31.9672131147541, Blast_Score=124, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24653477, Length=244, Percent_Identity=31.9672131147541, Blast_Score=124, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24653139, Length=250, Percent_Identity=31.2, Blast_Score=114, Evalue=9e-26,
Organism=Drosophila melanogaster, GI19922422, Length=246, Percent_Identity=30.4878048780488, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24654903, Length=182, Percent_Identity=27.4725274725275, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI19920382, Length=214, Percent_Identity=25.7009345794392, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21357171, Length=261, Percent_Identity=25.6704980842912, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 27737; Mature: 27606

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAQLLSRRTGSTLVLTLSNPDARNALDPVMYTASMEALNLAAKDKEIRSVIFTGADGAF
CCHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCE
CAGGNLNRLLENRSKPKHVQEEGIDALNHWIETIRTFPKPVIAAVEGPAAGAGFSLVLAC
ECCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHEEEECCCCCCCCHHHHHHH
DFVVAAADAKFVMAYVNVALTPDGGGSWHIARFLPRPLASEIIMLGKPVSAERLAHFGLV
HHHHHHCCHHHEEEEEEEEECCCCCCCCHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHH
NEVVRPGAALDRALLLAEQLAAQSPHAVGRIKGLIAHAEEASLHAHLQAEQHSFVEALHH
HHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADGNEGISAFLHKRQPQYR
CCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TAQLLSRRTGSTLVLTLSNPDARNALDPVMYTASMEALNLAAKDKEIRSVIFTGADGAF
CHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCE
CAGGNLNRLLENRSKPKHVQEEGIDALNHWIETIRTFPKPVIAAVEGPAAGAGFSLVLAC
ECCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHEEEECCCCCCCCHHHHHHH
DFVVAAADAKFVMAYVNVALTPDGGGSWHIARFLPRPLASEIIMLGKPVSAERLAHFGLV
HHHHHHCCHHHEEEEEEEEECCCCCCCCHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHH
NEVVRPGAALDRALLLAEQLAAQSPHAVGRIKGLIAHAEEASLHAHLQAEQHSFVEALHH
HHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADGNEGISAFLHKRQPQYR
CCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]