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The map label for this gene is intZ [H]

Identifier: 17546615

GI number: 17546615

Start: 2084602

End: 2085837

Strand: Direct

Name: intZ [H]

Synonym: RSc1896

Alternate gene names: 17546615

Gene position: 2084602-2085837 (Clockwise)

Preceding gene: 17546611

Following gene: 17546626

Centisome position: 56.09

GC content: 66.02

Gene sequence:

>1236_bases
ATGGCATCTTCCAGACAGCTTCACCGCTTGAACGCCCTGCGCGTCGCCAAAGAAGTGGCGCCCGGCTACCACGCCGACGG
CGGCGGCCTGTATCTCCAGATTTCGACGAGCGGGTCGCGCTCATGGATTTTCCGTTACTCCCTGGCGAAGCGGGCGCGGG
AGATGGGCCTGGGCCCGCTGTCCGCGATCTCGCTGGCCGAGGCCCGCGCGCAGGCCGCTCACAGCCGCAAGCTGCTTGCC
ACCGGCATCGACCCGATCGAGAGTCGCAAGGAACGCGAACGCGCTGCCCAGGCCACCCCTGACGGGTTGCTATTCCGCGA
CGCCGCCCGAGACTACATCAATGCCCACCGGGACAGCTGGAGGAACGCCAAGCACGCCCAGCAGTGGGAAAACACCCTTG
AGACCTACGCCTACCCGGTCATCGGCGATGTGGACGTGCGCGACATCGACACGGGCATGGTCGTGCGCGTACTGCAACCC
ATCTGGATGAAGAAGGCGGAGACGGCCAGCCGCGTACGCGGGCGCATTGAGTGCGTGCTCGATGCCGCCAAGGTCCTTGG
CAAGCGCAGCGGCGAGAACCCGGCGCTCTGGCGCGGCCACCTGGACAAGCTTCTGCCGAAGCGCGATCGCGCCAAGAAGG
TGAAACACCATCCAGCCTTGCCCTGGGCGGACATCCCCGGCTTCATGCCGGAACTTGCGGAACGCGCAGCCCCGGCGGCC
CGCGTGCTGCACCTCCTCATCCTCACCTGTGTGCGCACGACCGAGGCACTGGAGGCCAAGCCGGAAGAGTTCGACCTGGA
CCGGCGTATCTGGATCGTGCCGCCCGACCGGATGAAGATGGAAAAGGAGCTGCGCGTGCCGCTGAGCGAGCCGGCGGTGC
AGATCGTGAAAGAAGCGCTGAAGACGGCCGACGGCTACCTGTTCCCCGGCCAGAAGAAAGGCAAGCCGCTATCGAACATG
GCCATGCTGAACATGCTCGACCGCATGGGCTACGAAGGGATCACCGTGCACGGCTTCCGGTCGACGTTCCGCGACTGGGT
GGCCGAGTGCACCGAATACCCAGACTCGCTCGCCGAGATGGCGCTGGCGCACGCAGTGGAAAGCAAGGTGGAAGGCGCCT
ACCGCCGGGGGGACATGCTTGAGCGGCGGCGCCGGATGATGGAAGACTGGGCCCGCTATTGCAGCGGGCAAACGGGTGTA
GTGGTACCGCTCAAGCGAGAGGCTTCAGCAGCGTGA

Upstream 100 bases:

>100_bases
AAACGCCGCCTGAACGCGGGTTTTGGGGGTAACGGCGTTCTTGCCGCCTCCCAGCGCCCCTCACATAATCCACCCATCAA
TTGTGGGTAGAAACGTGGGT

Downstream 100 bases:

>100_bases
CGCCCGGCTTTGGTATTGGCCTGCCGGCCCTCATGGCAAGCCAGGCGTCGATGTCTTCGTCCAGCCAGGCGGTACGGTTG
CCGCCGAGCGAGAACGGCTT

Product: integrase prophage protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MASSRQLHRLNALRVAKEVAPGYHADGGGLYLQISTSGSRSWIFRYSLAKRAREMGLGPLSAISLAEARAQAAHSRKLLA
TGIDPIESRKERERAAQATPDGLLFRDAARDYINAHRDSWRNAKHAQQWENTLETYAYPVIGDVDVRDIDTGMVVRVLQP
IWMKKAETASRVRGRIECVLDAAKVLGKRSGENPALWRGHLDKLLPKRDRAKKVKHHPALPWADIPGFMPELAERAAPAA
RVLHLLILTCVRTTEALEAKPEEFDLDRRIWIVPPDRMKMEKELRVPLSEPAVQIVKEALKTADGYLFPGQKKGKPLSNM
AMLNMLDRMGYEGITVHGFRSTFRDWVAECTEYPDSLAEMALAHAVESKVEGAYRRGDMLERRRRMMEDWARYCSGQTGV
VVPLKREASAA

Sequences:

>Translated_411_residues
MASSRQLHRLNALRVAKEVAPGYHADGGGLYLQISTSGSRSWIFRYSLAKRAREMGLGPLSAISLAEARAQAAHSRKLLA
TGIDPIESRKERERAAQATPDGLLFRDAARDYINAHRDSWRNAKHAQQWENTLETYAYPVIGDVDVRDIDTGMVVRVLQP
IWMKKAETASRVRGRIECVLDAAKVLGKRSGENPALWRGHLDKLLPKRDRAKKVKHHPALPWADIPGFMPELAERAAPAA
RVLHLLILTCVRTTEALEAKPEEFDLDRRIWIVPPDRMKMEKELRVPLSEPAVQIVKEALKTADGYLFPGQKKGKPLSNM
AMLNMLDRMGYEGITVHGFRSTFRDWVAECTEYPDSLAEMALAHAVESKVEGAYRRGDMLERRRRMMEDWARYCSGQTGV
VVPLKREASAA
>Mature_410_residues
ASSRQLHRLNALRVAKEVAPGYHADGGGLYLQISTSGSRSWIFRYSLAKRAREMGLGPLSAISLAEARAQAAHSRKLLAT
GIDPIESRKERERAAQATPDGLLFRDAARDYINAHRDSWRNAKHAQQWENTLETYAYPVIGDVDVRDIDTGMVVRVLQPI
WMKKAETASRVRGRIECVLDAAKVLGKRSGENPALWRGHLDKLLPKRDRAKKVKHHPALPWADIPGFMPELAERAAPAAR
VLHLLILTCVRTTEALEAKPEEFDLDRRIWIVPPDRMKMEKELRVPLSEPAVQIVKEALKTADGYLFPGQKKGKPLSNMA
MLNMLDRMGYEGITVHGFRSTFRDWVAECTEYPDSLAEMALAHAVESKVEGAYRRGDMLERRRRMMEDWARYCSGQTGVV
VPLKREASAA

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI145693166, Length=369, Percent_Identity=34.4173441734417, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1788974, Length=395, Percent_Identity=31.8987341772152, Blast_Score=154, Evalue=9e-39,
Organism=Escherichia coli, GI1788690, Length=377, Percent_Identity=28.3819628647215, Blast_Score=137, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 46278; Mature: 46147

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASSRQLHRLNALRVAKEVAPGYHADGGGLYLQISTSGSRSWIFRYSLAKRAREMGLGPL
CCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCH
SAISLAEARAQAAHSRKLLATGIDPIESRKERERAAQATPDGLLFRDAARDYINAHRDSW
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
RNAKHAQQWENTLETYAYPVIGDVDVRDIDTGMVVRVLQPIWMKKAETASRVRGRIECVL
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAAKVLGKRSGENPALWRGHLDKLLPKRDRAKKVKHHPALPWADIPGFMPELAERAAPAA
HHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHH
RVLHLLILTCVRTTEALEAKPEEFDLDRRIWIVPPDRMKMEKELRVPLSEPAVQIVKEAL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHCCCCCCHHHHHHHHHH
KTADGYLFPGQKKGKPLSNMAMLNMLDRMGYEGITVHGFRSTFRDWVAECTEYPDSLAEM
HHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCHHHHHHH
ALAHAVESKVEGAYRRGDMLERRRRMMEDWARYCSGQTGVVVPLKREASAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
ASSRQLHRLNALRVAKEVAPGYHADGGGLYLQISTSGSRSWIFRYSLAKRAREMGLGPL
CCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCH
SAISLAEARAQAAHSRKLLATGIDPIESRKERERAAQATPDGLLFRDAARDYINAHRDSW
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
RNAKHAQQWENTLETYAYPVIGDVDVRDIDTGMVVRVLQPIWMKKAETASRVRGRIECVL
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAAKVLGKRSGENPALWRGHLDKLLPKRDRAKKVKHHPALPWADIPGFMPELAERAAPAA
HHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHH
RVLHLLILTCVRTTEALEAKPEEFDLDRRIWIVPPDRMKMEKELRVPLSEPAVQIVKEAL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHCCCCCCHHHHHHHHHH
KTADGYLFPGQKKGKPLSNMAMLNMLDRMGYEGITVHGFRSTFRDWVAECTEYPDSLAEM
HHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCHHHHHHH
ALAHAVESKVEGAYRRGDMLERRRRMMEDWARYCSGQTGVVVPLKREASAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]