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The map label for this gene is dnaQ [H]

Identifier: 17546591

GI number: 17546591

Start: 2056345

End: 2057073

Strand: Reverse

Name: dnaQ [H]

Synonym: RSc1872

Alternate gene names: 17546591

Gene position: 2057073-2056345 (Counterclockwise)

Preceding gene: 17546592

Following gene: 17546590

Centisome position: 55.35

GC content: 67.9

Gene sequence:

>729_bases
ATGCGACAGATCGTCCTCGATACCGAAACCACCGGCCTGAATGCCGCCACCGGCGACCGCGTGATCGAAATCGGCTGCGT
GGAGCTGGTCAACCGGCGGCTGACCGGCCGCAACCTGCATTTCTACCTCAACCCCGAGCGCGAGATCGACGCCGGCGCCA
TGGCGGTGCACGGCATTACCAACGAGTTCGTCGCCGACAAGCCCAAGTTCGCCGAGGTCGTCGACGAGATCCGGGACTAC
GTGCAGGGCGCCGAGGCGATCATCCATAACGCCGCGTTCGACCTGGGCTTCCTCGACATGGAGTTCAAGCGGTTGGGGCT
GCCGCCGTTCCGCGAGCATCTGGCCGGCCACATCGACACGCTGCTCGATGCGCGCCGGATGTTCCCCGGCAAGCGCAACT
CGCTGGACGCGCTGTGCGACCGCCTCGGCGTGAGCAACGCCCACCGTACGCTGCACGGCGCCTTGCTGGACGCGGAACTG
CTGGCCGAAGTCTATCTGGCCATGACGCGCGGCCAGAACACGCTGGTGATCGACATGTTGGAGAGCGGCGAGACGGCCGC
CGCCGAGGCCGCCGTGATCGACCTGAGCGGCCTGGAGCTGCCGATCCTGCTGGCGACCGAAGCGGAAGCCGCGGCGCACG
CGACCGTGCTCAAGGAGATCGACAAGGCCAGCGGCGGCAAGACGGTCTGGCTTCGGGATGCTCCGGAGGCCGCGCCGCAG
GCGGGCTGA

Upstream 100 bases:

>100_bases
GCGTGGCGCTGGCCCGCGCCGTGAAGTGGCACGCCGAGCACCGAATCCTGCTGAACGGCCACAAGACCGTCGTCTTCAAG
TAACCGACACGGAGCGCGCG

Downstream 100 bases:

>100_bases
TGAAAAAAATGCAGCAGGGGCTTTACACGGTCCCTGCCTTTTGCCATAATCACGTTTTCACCGCACACGGGTGGTTAGCT
CAGCGGTAGAGCACTGCCTT

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MRQIVLDTETTGLNAATGDRVIEIGCVELVNRRLTGRNLHFYLNPEREIDAGAMAVHGITNEFVADKPKFAEVVDEIRDY
VQGAEAIIHNAAFDLGFLDMEFKRLGLPPFREHLAGHIDTLLDARRMFPGKRNSLDALCDRLGVSNAHRTLHGALLDAEL
LAEVYLAMTRGQNTLVIDMLESGETAAAEAAVIDLSGLELPILLATEAEAAAHATVLKEIDKASGGKTVWLRDAPEAAPQ
AG

Sequences:

>Translated_242_residues
MRQIVLDTETTGLNAATGDRVIEIGCVELVNRRLTGRNLHFYLNPEREIDAGAMAVHGITNEFVADKPKFAEVVDEIRDY
VQGAEAIIHNAAFDLGFLDMEFKRLGLPPFREHLAGHIDTLLDARRMFPGKRNSLDALCDRLGVSNAHRTLHGALLDAEL
LAEVYLAMTRGQNTLVIDMLESGETAAAEAAVIDLSGLELPILLATEAEAAAHATVLKEIDKASGGKTVWLRDAPEAAPQ
AG
>Mature_242_residues
MRQIVLDTETTGLNAATGDRVIEIGCVELVNRRLTGRNLHFYLNPEREIDAGAMAVHGITNEFVADKPKFAEVVDEIRDY
VQGAEAIIHNAAFDLGFLDMEFKRLGLPPFREHLAGHIDTLLDARRMFPGKRNSLDALCDRLGVSNAHRTLHGALLDAEL
LAEVYLAMTRGQNTLVIDMLESGETAAAEAAVIDLSGLELPILLATEAEAAAHATVLKEIDKASGGKTVWLRDAPEAAPQ
AG

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=236, Percent_Identity=52.5423728813559, Blast_Score=233, Evalue=7e-63,
Organism=Escherichia coli, GI1788149, Length=234, Percent_Identity=28.6324786324786, Blast_Score=68, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 26231; Mature: 26231

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQIVLDTETTGLNAATGDRVIEIGCVELVNRRLTGRNLHFYLNPEREIDAGAMAVHGIT
CCEEEEECCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEECCCC
NEFVADKPKFAEVVDEIRDYVQGAEAIIHNAAFDLGFLDMEFKRLGLPPFREHLAGHIDT
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHH
LLDARRMFPGKRNSLDALCDRLGVSNAHRTLHGALLDAELLAEVYLAMTRGQNTLVIDML
HHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
ESGETAAAEAAVIDLSGLELPILLATEAEAAAHATVLKEIDKASGGKTVWLRDAPEAAPQ
CCCCCHHHHEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCC
AG
CC
>Mature Secondary Structure
MRQIVLDTETTGLNAATGDRVIEIGCVELVNRRLTGRNLHFYLNPEREIDAGAMAVHGIT
CCEEEEECCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEECCCC
NEFVADKPKFAEVVDEIRDYVQGAEAIIHNAAFDLGFLDMEFKRLGLPPFREHLAGHIDT
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHH
LLDARRMFPGKRNSLDALCDRLGVSNAHRTLHGALLDAELLAEVYLAMTRGQNTLVIDML
HHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
ESGETAAAEAAVIDLSGLELPILLATEAEAAAHATVLKEIDKASGGKTVWLRDAPEAAPQ
CCCCCHHHHEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCC
AG
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]