Click here to switch to the map view.

The map label for this gene is intB [H]

Identifier: 17546590

GI number: 17546590

Start: 2054819

End: 2056036

Strand: Reverse

Name: intB [H]

Synonym: RSc1871

Alternate gene names: 17546590

Gene position: 2056036-2054819 (Counterclockwise)

Preceding gene: 17546591

Following gene: 17546589

Centisome position: 55.32

GC content: 66.58

Gene sequence:

>1218_bases
ATGGCACTCACCGACACCGCAATCCGCAACGCTAAGCCTGCCGACAAGCCGATCAAGCTGTTCGACGGTGGCGGCTTGTT
TCTCCACGTCACGCCCGCTGGCCAGCGCTACTGGCGGCTGAAGTATCGGTTCGCGGGCAAGGAGAAGCTGCTGGCCATTG
GCGTCTACCCGGAAATTGGCCTGAAAGAGGCGAGGGACCGGCGTGAGGAAGCCAAACGGCTGCTGGGCGAGGGTGTTGAC
CCGTCAGTCGAGCGCAAGGTGCGGAAGGTGGCGACGGTCGAGCGGGCGGCGAACAGCTTCGAGGCCGTGGCCCGCGAGTG
GCACGCCAAGTACGCGCCGGGCTGGTCCGAGAGCAATGCCAAGAAGGTGCTGGCTCGCCTGGAGAACGACGTGTTCCCCT
GGCTTGGTGGCCGGCCGATCGCCGAAGTGAAGGCGCCCGAGCTGCTGGGCGTGGCCCGCCGCGTCGAGTCTCGCGGCGCC
CTGGATACTGCGCACCGCGTGCTGCAAACCTGCGGCCAGATCTTCCGCTACGCCGTTGCCACCGGCCGGGCAGAGCGTGA
TCCCTCGGGCGACCTGCGGGGCGCCTTGCCGCCGGCCAAGGGGAAGCACTACGCCGCGCCGACTGATCCCAAGGAGGTGG
CAGGGCTGCTGCGCATGTTCGACGGTTTTACCGGCACATTCATCGTGAAATGCGCGCTGCTGCTGGCGCCGATGGTCTTC
GTTCGGCCTGGCGAGTTGCGCGCGGCGGAATGGGCGGACATCGATCTGGATGCGGCCGAATGGCGCTTCGTGTCTTCCAA
GCGGGATGTGGCTCACATCGTGCCGCTCTCCACCCAGGCCGTCGCAATCCTGCGTGACCTGCACGCGCTGACCGGCCACG
GACGTTACCTCTTCCCCGGTGCGCGGGACAAAGCCAAACCCATGTCCGAGGCGGCCATCAATGCTGCGCTCAAGCGCATG
GGCATCGACACGCAGAAGGAGTTCACCGGCCATGGCGTGCGCCCGATTGCCCGCACTATCTTGCGCGAGGTGCTGGGCTT
CGAGGCGGAGGTGATCGAGTTGCAGCTTGCGCACCGGAAGAAAGACCCCAACGGCGCGGCGTATGACCGGGTGGCGTTCC
TGGCCGTGCGCAAGCAGATGATGCAGGCTTGGGCGGACTACCTGGACGAATTGAAGGCCGGGGCCAAGGTGCTGCCGCTC
AAGGGTTCCGCGGCGTAG

Upstream 100 bases:

>100_bases
TTTCTTGCCCGCGTTGCCCAAGTTTGCCCATTGGCAGCAGGGGGTATGTGGGGGTATTTTTGGGGGTACATCTGATACCC
CCAGCTGGAGATACCCCCAG

Downstream 100 bases:

>100_bases
GGCTTGCCGTCTTCCCAGCCTGCGCCGCTACTGTTCATCCATCCAGTACAATCACCCAACGTTGCCAAGTGACGGCAACG
ACAGCTTAAGCCGCGCCTAG

Product: integrase prophage protein

Products: NA

Alternate protein names: Int(P4) [H]

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MALTDTAIRNAKPADKPIKLFDGGGLFLHVTPAGQRYWRLKYRFAGKEKLLAIGVYPEIGLKEARDRREEAKRLLGEGVD
PSVERKVRKVATVERAANSFEAVAREWHAKYAPGWSESNAKKVLARLENDVFPWLGGRPIAEVKAPELLGVARRVESRGA
LDTAHRVLQTCGQIFRYAVATGRAERDPSGDLRGALPPAKGKHYAAPTDPKEVAGLLRMFDGFTGTFIVKCALLLAPMVF
VRPGELRAAEWADIDLDAAEWRFVSSKRDVAHIVPLSTQAVAILRDLHALTGHGRYLFPGARDKAKPMSEAAINAALKRM
GIDTQKEFTGHGVRPIARTILREVLGFEAEVIELQLAHRKKDPNGAAYDRVAFLAVRKQMMQAWADYLDELKAGAKVLPL
KGSAA

Sequences:

>Translated_405_residues
MALTDTAIRNAKPADKPIKLFDGGGLFLHVTPAGQRYWRLKYRFAGKEKLLAIGVYPEIGLKEARDRREEAKRLLGEGVD
PSVERKVRKVATVERAANSFEAVAREWHAKYAPGWSESNAKKVLARLENDVFPWLGGRPIAEVKAPELLGVARRVESRGA
LDTAHRVLQTCGQIFRYAVATGRAERDPSGDLRGALPPAKGKHYAAPTDPKEVAGLLRMFDGFTGTFIVKCALLLAPMVF
VRPGELRAAEWADIDLDAAEWRFVSSKRDVAHIVPLSTQAVAILRDLHALTGHGRYLFPGARDKAKPMSEAAINAALKRM
GIDTQKEFTGHGVRPIARTILREVLGFEAEVIELQLAHRKKDPNGAAYDRVAFLAVRKQMMQAWADYLDELKAGAKVLPL
KGSAA
>Mature_404_residues
ALTDTAIRNAKPADKPIKLFDGGGLFLHVTPAGQRYWRLKYRFAGKEKLLAIGVYPEIGLKEARDRREEAKRLLGEGVDP
SVERKVRKVATVERAANSFEAVAREWHAKYAPGWSESNAKKVLARLENDVFPWLGGRPIAEVKAPELLGVARRVESRGAL
DTAHRVLQTCGQIFRYAVATGRAERDPSGDLRGALPPAKGKHYAAPTDPKEVAGLLRMFDGFTGTFIVKCALLLAPMVFV
RPGELRAAEWADIDLDAAEWRFVSSKRDVAHIVPLSTQAVAILRDLHALTGHGRYLFPGARDKAKPMSEAAINAALKRMG
IDTQKEFTGHGVRPIARTILREVLGFEAEVIELQLAHRKKDPNGAAYDRVAFLAVRKQMMQAWADYLDELKAGAKVLPLK
GSAA

Specific function: Unknown

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1788690, Length=395, Percent_Identity=34.4303797468354, Blast_Score=235, Evalue=3e-63,
Organism=Escherichia coli, GI145693166, Length=397, Percent_Identity=38.2871536523929, Blast_Score=227, Evalue=1e-60,
Organism=Escherichia coli, GI1788974, Length=400, Percent_Identity=33.5, Blast_Score=219, Evalue=2e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 44622; Mature: 44491

Theoretical pI: Translated: 10.37; Mature: 10.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTDTAIRNAKPADKPIKLFDGGGLFLHVTPAGQRYWRLKYRFAGKEKLLAIGVYPEIG
CCCCCHHHCCCCCCCCCEEEEECCEEEEEEECCCCEEEEEEEEECCCCEEEEEECCCCCC
LKEARDRREEAKRLLGEGVDPSVERKVRKVATVERAANSFEAVAREWHAKYAPGWSESNA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
KKVLARLENDVFPWLGGRPIAEVKAPELLGVARRVESRGALDTAHRVLQTCGQIFRYAVA
HHHHHHHHHCCCCCCCCCCCHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
TGRAERDPSGDLRGALPPAKGKHYAAPTDPKEVAGLLRMFDGFTGTFIVKCALLLAPMVF
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
VRPGELRAAEWADIDLDAAEWRFVSSKRDVAHIVPLSTQAVAILRDLHALTGHGRYLFPG
CCCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCEECCC
ARDKAKPMSEAAINAALKRMGIDTQKEFTGHGVRPIARTILREVLGFEAEVIELQLAHRK
CCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCC
KDPNGAAYDRVAFLAVRKQMMQAWADYLDELKAGAKVLPLKGSAA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCC
>Mature Secondary Structure 
ALTDTAIRNAKPADKPIKLFDGGGLFLHVTPAGQRYWRLKYRFAGKEKLLAIGVYPEIG
CCCCHHHCCCCCCCCCEEEEECCEEEEEEECCCCEEEEEEEEECCCCEEEEEECCCCCC
LKEARDRREEAKRLLGEGVDPSVERKVRKVATVERAANSFEAVAREWHAKYAPGWSESNA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
KKVLARLENDVFPWLGGRPIAEVKAPELLGVARRVESRGALDTAHRVLQTCGQIFRYAVA
HHHHHHHHHCCCCCCCCCCCHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
TGRAERDPSGDLRGALPPAKGKHYAAPTDPKEVAGLLRMFDGFTGTFIVKCALLLAPMVF
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
VRPGELRAAEWADIDLDAAEWRFVSSKRDVAHIVPLSTQAVAILRDLHALTGHGRYLFPG
CCCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCEECCC
ARDKAKPMSEAAINAALKRMGIDTQKEFTGHGVRPIARTILREVLGFEAEVIELQLAHRK
CCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCC
KDPNGAAYDRVAFLAVRKQMMQAWADYLDELKAGAKVLPLKGSAA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]