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The map label for this gene is potH [H]

Identifier: 17546451

GI number: 17546451

Start: 1852895

End: 1854157

Strand: Reverse

Name: potH [H]

Synonym: RSc1732

Alternate gene names: 17546451

Gene position: 1854157-1852895 (Counterclockwise)

Preceding gene: 17546452

Following gene: 17546450

Centisome position: 49.89

GC content: 69.44

Gene sequence:

>1263_bases
ATGACGATCACGGCTGACACGACCCCCGATTCGACAGCCAGACTCAAACGCGAGCTCAAGAGCGCGGAAGCGCGCCGGCG
CGCCATGGCGCTGGCCCTGGTGGCGCCGCTCGCCCTCTTCCTCTTGCTCATCTTCGTGGTGCCGATCGGCGCGCTGCTGA
CCCGCGCGGTGCAGAACCCCGAGGTGGCGGACGCCCTACCCAGGACGGTCGCCGCGCTCAAGAGCTGGGACCGCAGGACC
CCGCCGGCCGACGCCGCCTACGCCGCCCTCGCCGACGACCTGACCGCCACGCAGGCCGGCGAGGCGATGGGCGCCCTGGC
CCGCCGCCTGAACACCGAAATCTCCGGCTTCCGCTCGCTGGTCGCCAAGACCGCGCGCGCCATGCCGCTCGCCGACGAAC
AAGGCCATGCGCTGGCGCCGGCCCAGACCCGCGCCCGGCTGGTCGAGCTCGACGAGCGCTGGGCCGACACCGCCTACTGG
CAGGCCATCGCCAAGAACAGCAGCCGCACCTCGCCGTTCTACCTGCTGGCCGCGCTCGACCACCGCCAGGACGCCTTCGG
CCATATCGAGGCGACCGACCCCGACGAGCAGATCTACGTCACCGTGTTCGGCCGCACCTTCGTCATCAGCGCCGTGGTCA
CGCTGCTCACGCTGCTGCTGGGCTACCCGCTGGCGTACTGGATCTCGACGCTGTCGGAGCGCCGCGCCAACCTGGTGATG
GTGCTGGTGCTGATTCCGTTCTGGACCTCGATCCTGGTGCGCGTGGCCGCGTGGATCGTGCTGCTGCAGAGCGAGGGCCT
CGTCAACCATGCGCTGACGGGCCTGGGGCTGATCCGCGAGCCGCTGGCGCTGCTGTTCAACCGCATCGGCGTCTATATCT
CGATGACGCACATCCTGCTGCCGTTCATGATCCTGCCCCTGTACAGCGTGATGAAGTCGGTCCCGTCCACCTACCAGCGT
GCGGCGGTGTCGCTGGGCAGCCATCCGTTCGCGGCGTTCTGGCGCGTGTATGTGCCGCAGACCTACCCGGGCGTGGGTGC
CGGCGCGCTGCTGGTGTTCATCCTCGCGCTCGGCTACTACATCACGCCCGCGCTGCTGGGCGGCCCGAACGACCAGATGG
TCAGCTACTACGTGGCGTACTTCACCAACGTCACCATCAACTGGGGCATGGCATGCGCGCTGGGCGCGCTGCTGCTGGCG
GCCACGCTGGTGCTGTACGGCGTCTACGGCCGCTTCACGCGCGCCAAGGCCAACGCGCGCTGA

Upstream 100 bases:

>100_bases
AAGCAGGCCGCCCGGGCCGGCGCGCTCGCATGCTCCGGCATGCCCCGGCGCCGGCCCGACATGAAGGGTGCAGGACACGG
CAGGTGCAGAATTGAACACC

Downstream 100 bases:

>100_bases
AGAAAGGAGCCGATCATGAAATTCGCCAGGCCGATGTTCGCCCCGCACACCTCGCTCATCGAGCGCATCTGGTACTTCGC
GCTGCGCGGCCTGGCCGTGC

Product: transport system permease transmembrane protein

Products: ADP; phosphate; putrescine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MTITADTTPDSTARLKRELKSAEARRRAMALALVAPLALFLLLIFVVPIGALLTRAVQNPEVADALPRTVAALKSWDRRT
PPADAAYAALADDLTATQAGEAMGALARRLNTEISGFRSLVAKTARAMPLADEQGHALAPAQTRARLVELDERWADTAYW
QAIAKNSSRTSPFYLLAALDHRQDAFGHIEATDPDEQIYVTVFGRTFVISAVVTLLTLLLGYPLAYWISTLSERRANLVM
VLVLIPFWTSILVRVAAWIVLLQSEGLVNHALTGLGLIREPLALLFNRIGVYISMTHILLPFMILPLYSVMKSVPSTYQR
AAVSLGSHPFAAFWRVYVPQTYPGVGAGALLVFILALGYYITPALLGGPNDQMVSYYVAYFTNVTINWGMACALGALLLA
ATLVLYGVYGRFTRAKANAR

Sequences:

>Translated_420_residues
MTITADTTPDSTARLKRELKSAEARRRAMALALVAPLALFLLLIFVVPIGALLTRAVQNPEVADALPRTVAALKSWDRRT
PPADAAYAALADDLTATQAGEAMGALARRLNTEISGFRSLVAKTARAMPLADEQGHALAPAQTRARLVELDERWADTAYW
QAIAKNSSRTSPFYLLAALDHRQDAFGHIEATDPDEQIYVTVFGRTFVISAVVTLLTLLLGYPLAYWISTLSERRANLVM
VLVLIPFWTSILVRVAAWIVLLQSEGLVNHALTGLGLIREPLALLFNRIGVYISMTHILLPFMILPLYSVMKSVPSTYQR
AAVSLGSHPFAAFWRVYVPQTYPGVGAGALLVFILALGYYITPALLGGPNDQMVSYYVAYFTNVTINWGMACALGALLLA
ATLVLYGVYGRFTRAKANAR
>Mature_419_residues
TITADTTPDSTARLKRELKSAEARRRAMALALVAPLALFLLLIFVVPIGALLTRAVQNPEVADALPRTVAALKSWDRRTP
PADAAYAALADDLTATQAGEAMGALARRLNTEISGFRSLVAKTARAMPLADEQGHALAPAQTRARLVELDERWADTAYWQ
AIAKNSSRTSPFYLLAALDHRQDAFGHIEATDPDEQIYVTVFGRTFVISAVVTLLTLLLGYPLAYWISTLSERRANLVMV
LVLIPFWTSILVRVAAWIVLLQSEGLVNHALTGLGLIREPLALLFNRIGVYISMTHILLPFMILPLYSVMKSVPSTYQRA
AVSLGSHPFAAFWRVYVPQTYPGVGAGALLVFILALGYYITPALLGGPNDQMVSYYVAYFTNVTINWGMACALGALLLAA
TLVLYGVYGRFTRAKANAR

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine [H]

COG id: COG1176

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component I

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787080, Length=212, Percent_Identity=35.377358490566, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1787369, Length=220, Percent_Identity=31.3636363636364, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1787713, Length=180, Percent_Identity=31.1111111111111, Blast_Score=89, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 45839; Mature: 45708

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTITADTTPDSTARLKRELKSAEARRRAMALALVAPLALFLLLIFVVPIGALLTRAVQNP
CEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EVADALPRTVAALKSWDRRTPPADAAYAALADDLTATQAGEAMGALARRLNTEISGFRSL
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAKTARAMPLADEQGHALAPAQTRARLVELDERWADTAYWQAIAKNSSRTSPFYLLAALD
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHH
HRQDAFGHIEATDPDEQIYVTVFGRTFVISAVVTLLTLLLGYPLAYWISTLSERRANLVM
CCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLVLIPFWTSILVRVAAWIVLLQSEGLVNHALTGLGLIREPLALLFNRIGVYISMTHILL
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PFMILPLYSVMKSVPSTYQRAAVSLGSHPFAAFWRVYVPQTYPGVGAGALLVFILALGYY
HHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
ITPALLGGPNDQMVSYYVAYFTNVTINWGMACALGALLLAATLVLYGVYGRFTRAKANAR
HHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TITADTTPDSTARLKRELKSAEARRRAMALALVAPLALFLLLIFVVPIGALLTRAVQNP
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EVADALPRTVAALKSWDRRTPPADAAYAALADDLTATQAGEAMGALARRLNTEISGFRSL
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAKTARAMPLADEQGHALAPAQTRARLVELDERWADTAYWQAIAKNSSRTSPFYLLAALD
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHH
HRQDAFGHIEATDPDEQIYVTVFGRTFVISAVVTLLTLLLGYPLAYWISTLSERRANLVM
CCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLVLIPFWTSILVRVAAWIVLLQSEGLVNHALTGLGLIREPLALLFNRIGVYISMTHILL
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PFMILPLYSVMKSVPSTYQRAAVSLGSHPFAAFWRVYVPQTYPGVGAGALLVFILALGYY
HHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
ITPALLGGPNDQMVSYYVAYFTNVTINWGMACALGALLLAATLVLYGVYGRFTRAKANAR
HHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; putrescine [Periplasm]; H2O [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8416922; 8905232; 9278503 [H]