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The map label for this gene is ompR [H]

Identifier: 17546367

GI number: 17546367

Start: 1771950

End: 1772672

Strand: Reverse

Name: ompR [H]

Synonym: RSc1648

Alternate gene names: 17546367

Gene position: 1772672-1771950 (Counterclockwise)

Preceding gene: 17546371

Following gene: 17546366

Centisome position: 47.7

GC content: 66.67

Gene sequence:

>723_bases
ATGGAAAATTCCGGTCACAAGATTCTCGTCGTCGACGACGATCCCCGCCTGCGCGACCTGCTGCGCCGCTACCTTGGGGA
ACAGGGCTTCACCGTGCTGGTGGCGGAAAACGCCACGGCCATGAACAAACTCTGGCTGCGCGAGCGCTTCGACCTGCTGG
TGCTCGACCTGATGATGCCGGGCGAAGACGGCCTGTCGATCTGCCGACGCCTGCGGGGCGCCAACGACCAGACACCGATC
ATCATGCTCACCGCCAAGGGCGAGGACGTGGACCGCATCGTCGGCCTGGAGATGGGCGCCGACGACTACCTGCCCAAGCC
GTTCAACCCGCGCGAGCTGATCGCCCGCATCCATGCCGTGCTGCGCCGCCGCGGTCCGGCCGAGATTCCCGGCGCCCCGT
CGGAGACGCCCGAGACCTTCGCCTTCGGCGACTTCGTGCTGAACCTGGCCACCCGCACGCTCAAGAAGAACGACGAGGAA
ATCACCCTCACCACGGGCGAATTCTCCGTGCTCAAGGTGTTCGCGCGCCACCCGCGCCAGCCGCTGTCGCGCGAGAAGCT
GATGGAGATGGCGCGCGGCCGCGAGTACGAGGTCTTCGACCGCAGCCTGGACGTGCAGATCTCGCGCCTGCGCAAGCTGA
TCGAGCCGGACGCGAGCAACCCGCGCTTCATCCAGACGGTCTGGGGCCTGGGCTACGTGTTCATCCCGGACGGCGCCAAG
TAA

Upstream 100 bases:

>100_bases
TGCCGACTGTTCGCGGGACCGGGTAAATAATGTAACCGTCTGTTTCAATTGGGGTGATGGACCGCTTCAGGCCCGTGTTT
TTGTCGTTACCATTAGCGCC

Downstream 100 bases:

>100_bases
CGCGCGGCACGCCTCCAACCCTTCTTCCGCCCACGACTTGCGCATTCCGCGTCCGGCCGCGCTGCGGCGCCTGCTGATCA
GCGTATTCGGTTCGCTGTTC

Product: osmolarity response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MENSGHKILVVDDDPRLRDLLRRYLGEQGFTVLVAENATAMNKLWLRERFDLLVLDLMMPGEDGLSICRRLRGANDQTPI
IMLTAKGEDVDRIVGLEMGADDYLPKPFNPRELIARIHAVLRRRGPAEIPGAPSETPETFAFGDFVLNLATRTLKKNDEE
ITLTTGEFSVLKVFARHPRQPLSREKLMEMARGREYEVFDRSLDVQISRLRKLIEPDASNPRFIQTVWGLGYVFIPDGAK

Sequences:

>Translated_240_residues
MENSGHKILVVDDDPRLRDLLRRYLGEQGFTVLVAENATAMNKLWLRERFDLLVLDLMMPGEDGLSICRRLRGANDQTPI
IMLTAKGEDVDRIVGLEMGADDYLPKPFNPRELIARIHAVLRRRGPAEIPGAPSETPETFAFGDFVLNLATRTLKKNDEE
ITLTTGEFSVLKVFARHPRQPLSREKLMEMARGREYEVFDRSLDVQISRLRKLIEPDASNPRFIQTVWGLGYVFIPDGAK
>Mature_240_residues
MENSGHKILVVDDDPRLRDLLRRYLGEQGFTVLVAENATAMNKLWLRERFDLLVLDLMMPGEDGLSICRRLRGANDQTPI
IMLTAKGEDVDRIVGLEMGADDYLPKPFNPRELIARIHAVLRRRGPAEIPGAPSETPETFAFGDFVLNLATRTLKKNDEE
ITLTTGEFSVLKVFARHPRQPLSREKLMEMARGREYEVFDRSLDVQISRLRKLIEPDASNPRFIQTVWGLGYVFIPDGAK

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=238, Percent_Identity=65.546218487395, Blast_Score=323, Evalue=5e-90,
Organism=Escherichia coli, GI1786784, Length=233, Percent_Identity=37.7682403433476, Blast_Score=151, Evalue=3e-38,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=40.8695652173913, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1786599, Length=234, Percent_Identity=38.034188034188, Blast_Score=147, Evalue=4e-37,
Organism=Escherichia coli, GI1788394, Length=241, Percent_Identity=35.2697095435685, Blast_Score=147, Evalue=7e-37,
Organism=Escherichia coli, GI1787229, Length=233, Percent_Identity=35.6223175965665, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=33.7662337662338, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=37.4468085106383, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1790860, Length=228, Percent_Identity=33.7719298245614, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1786911, Length=229, Percent_Identity=32.7510917030568, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI87082012, Length=230, Percent_Identity=31.304347826087, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1787375, Length=234, Percent_Identity=35.4700854700855, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1790552, Length=231, Percent_Identity=32.4675324675325, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=30.2631578947368, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1790299, Length=110, Percent_Identity=33.6363636363636, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788905, Length=127, Percent_Identity=31.496062992126, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788191, Length=123, Percent_Identity=33.3333333333333, Blast_Score=61, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=133, Percent_Identity=30.8270676691729, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27318; Mature: 27318

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENSGHKILVVDDDPRLRDLLRRYLGEQGFTVLVAENATAMNKLWLRERFDLLVLDLMMP
CCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHEEEECCC
GEDGLSICRRLRGANDQTPIIMLTAKGEDVDRIVGLEMGADDYLPKPFNPRELIARIHAV
CCHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHEEEECCCCCCCCCCCCHHHHHHHHHHH
LRRRGPAEIPGAPSETPETFAFGDFVLNLATRTLKKNDEEITLTTGEFSVLKVFARHPRQ
HHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCC
PLSREKLMEMARGREYEVFDRSLDVQISRLRKLIEPDASNPRFIQTVWGLGYVFIPDGAK
CCCHHHHHHHHCCCCEEEHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEECCCCC
>Mature Secondary Structure
MENSGHKILVVDDDPRLRDLLRRYLGEQGFTVLVAENATAMNKLWLRERFDLLVLDLMMP
CCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHEEEECCC
GEDGLSICRRLRGANDQTPIIMLTAKGEDVDRIVGLEMGADDYLPKPFNPRELIARIHAV
CCHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHEEEECCCCCCCCCCCCHHHHHHHHHHH
LRRRGPAEIPGAPSETPETFAFGDFVLNLATRTLKKNDEEITLTTGEFSVLKVFARHPRQ
HHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCC
PLSREKLMEMARGREYEVFDRSLDVQISRLRKLIEPDASNPRFIQTVWGLGYVFIPDGAK
CCCHHHHHHHHCCCCEEEHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]