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The map label for this gene is comL [H]

Identifier: 17546346

GI number: 17546346

Start: 1748034

End: 1748903

Strand: Reverse

Name: comL [H]

Synonym: RSc1627

Alternate gene names: 17546346

Gene position: 1748903-1748034 (Counterclockwise)

Preceding gene: 17546349

Following gene: 17546342

Centisome position: 47.06

GC content: 61.49

Gene sequence:

>870_bases
ATGCTTGATGCGATTTTTCATTCAGACAAGGTGCCCATGTCGGTCACGAGCATGAAGCTGGCGCGCATTCGCGCGCGAAT
CGGAGCGGTATTGGCGGCGGGCGTTGCATGCCTCGCGATCTCGGCCTGCGGCATCATGCCGGAACAACAGGACGAGACCG
CAGGCTGGTCGGCCAACAAATTATATTCGGAAGCGAAGGACGCGCTCGACGGCGGCGACTACAGCAAGGCCGTCAAGTAC
TACGAAAAGCTCGAGAGCCGCTATCCGTTCGGGCCCTTTGCCCAGCAGGCGCAGATCGAAACCGCCTACGCCAATTACAA
GGACGGCGAAACCGCCGCCGCGCTGGCTGCGGTCGATCGCTTCATCCAGCTGCACCCGAATCACCCCAGCGTCGATTACG
CCTACTACCTCAAGGGCCTGATCAACTTCAACGACAACCTGGGCTGGCTGGGCCGCTTCTCCAACCAGGACCTGAGCGAG
CGCGATCCGAAGGCGGCCCGCGCCGCCTACGATGCGTTCAAGACGCTGATCACGCGTTTCCCGAACAGCAAGTACGCGCC
GGACGCCGCGCAGCGCATGCAGTACATCGTCAACGCGATGGCCGAGCATGAAGTGCAGGCCGCCCGCTACTACTACCGCC
GCGGCGCCTACCTGGCCGCCACCAACCGCGCGCAGGAAGCCATCAAGGATTACGATCGCGCGCCGGCCGTGGAAGAAGGG
CTGTACATCATGATGAAGTCCTACGAAGCGCTTGGCATGAAAGACCTGCGCGACGACACCGAGCGCATCATCAAGCAGAA
CTATCCGAACAGCGATTTCCTGCTGTACGGACAGCGCAAGAAGGCCAAGCCGTGGTACCAGTGGTGGTAA

Upstream 100 bases:

>100_bases
CGGACAGGTCGAGCGCCTCGTCGTCGAGCGTATCGTCGGCGTCTTGCGAGGCGGCTGGGAGGTCGGCCACTGCGTCGTCG
GACACAGGGCTTGGGCTATA

Downstream 100 bases:

>100_bases
GCCACGCGTGAACAGCGCCATCGCGCAATCAGGAAGCCCGGTCGATTGACCGGGCTTTTTTTCGCCCGCGCGCGGCGTCA
GGCGGAGGTGTCGGCCGCGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MLDAIFHSDKVPMSVTSMKLARIRARIGAVLAAGVACLAISACGIMPEQQDETAGWSANKLYSEAKDALDGGDYSKAVKY
YEKLESRYPFGPFAQQAQIETAYANYKDGETAAALAAVDRFIQLHPNHPSVDYAYYLKGLINFNDNLGWLGRFSNQDLSE
RDPKAARAAYDAFKTLITRFPNSKYAPDAAQRMQYIVNAMAEHEVQAARYYYRRGAYLAATNRAQEAIKDYDRAPAVEEG
LYIMMKSYEALGMKDLRDDTERIIKQNYPNSDFLLYGQRKKAKPWYQWW

Sequences:

>Translated_289_residues
MLDAIFHSDKVPMSVTSMKLARIRARIGAVLAAGVACLAISACGIMPEQQDETAGWSANKLYSEAKDALDGGDYSKAVKY
YEKLESRYPFGPFAQQAQIETAYANYKDGETAAALAAVDRFIQLHPNHPSVDYAYYLKGLINFNDNLGWLGRFSNQDLSE
RDPKAARAAYDAFKTLITRFPNSKYAPDAAQRMQYIVNAMAEHEVQAARYYYRRGAYLAATNRAQEAIKDYDRAPAVEEG
LYIMMKSYEALGMKDLRDDTERIIKQNYPNSDFLLYGQRKKAKPWYQWW
>Mature_289_residues
MLDAIFHSDKVPMSVTSMKLARIRARIGAVLAAGVACLAISACGIMPEQQDETAGWSANKLYSEAKDALDGGDYSKAVKY
YEKLESRYPFGPFAQQAQIETAYANYKDGETAAALAAVDRFIQLHPNHPSVDYAYYLKGLINFNDNLGWLGRFSNQDLSE
RDPKAARAAYDAFKTLITRFPNSKYAPDAAQRMQYIVNAMAEHEVQAARYYYRRGAYLAATNRAQEAIKDYDRAPAVEEG
LYIMMKSYEALGMKDLRDDTERIIKQNYPNSDFLLYGQRKKAKPWYQWW

Specific function: Required for efficient transformation of Neisseria gonorrhoeae by species-related DNA [H]

COG id: COG4105

COG function: function code R; DNA uptake lipoprotein

Gene ontology:

Cell location: Cell membrane; Lipid-anchor [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0169 (ComL) family [H]

Homologues:

Organism=Escherichia coli, GI1788947, Length=247, Percent_Identity=34.8178137651822, Blast_Score=171, Evalue=6e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017689
- InterPro:   IPR011990 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 32810; Mature: 32810

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDAIFHSDKVPMSVTSMKLARIRARIGAVLAAGVACLAISACGIMPEQQDETAGWSANK
CCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
LYSEAKDALDGGDYSKAVKYYEKLESRYPFGPFAQQAQIETAYANYKDGETAAALAAVDR
HHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHH
FIQLHPNHPSVDYAYYLKGLINFNDNLGWLGRFSNQDLSERDPKAARAAYDAFKTLITRF
HHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
PNSKYAPDAAQRMQYIVNAMAEHEVQAARYYYRRGAYLAATNRAQEAIKDYDRAPAVEEG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHCCCCHHHH
LYIMMKSYEALGMKDLRDDTERIIKQNYPNSDFLLYGQRKKAKPWYQWW
HHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MLDAIFHSDKVPMSVTSMKLARIRARIGAVLAAGVACLAISACGIMPEQQDETAGWSANK
CCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
LYSEAKDALDGGDYSKAVKYYEKLESRYPFGPFAQQAQIETAYANYKDGETAAALAAVDR
HHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHH
FIQLHPNHPSVDYAYYLKGLINFNDNLGWLGRFSNQDLSERDPKAARAAYDAFKTLITRF
HHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
PNSKYAPDAAQRMQYIVNAMAEHEVQAARYYYRRGAYLAATNRAQEAIKDYDRAPAVEEG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHCCCCHHHH
LYIMMKSYEALGMKDLRDDTERIIKQNYPNSDFLLYGQRKKAKPWYQWW
HHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8830266 [H]