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The map label for this gene is glcD [H]

Identifier: 17546275

GI number: 17546275

Start: 1672034

End: 1673446

Strand: Reverse

Name: glcD [H]

Synonym: RSc1556

Alternate gene names: 17546275

Gene position: 1673446-1672034 (Counterclockwise)

Preceding gene: 17546276

Following gene: 17546273

Centisome position: 45.03

GC content: 69.99

Gene sequence:

>1413_bases
ATGACCCACGATGCCTTCCTGCAGGCCTGCACCGACGCCATCGGCGGCGCGCACGTCCTGACCGCGCCGGAAGACCAGGC
ACCCTATCTGACCGACTGGCGCAAGCGCTTCACCGGCCGGGCACGCGCCGTGCTGCGCCCGGCCGATCCCGAGCAGGTCG
CCGCGCTGGTGCGCCTGTGCGCCGGCCATGGCGTGCCGATCGTCCCGCAGGGCGGCAACACCGGGCTGTGCGGCGGCGCC
ACGCCCGACGCCGCGGGCACGGCCGTGGTGATCTCGCTGCAGCGCCTGCAGCGCGTGCGCGCGGTCGATCCGATCAACAA
CACCATCACCGTGGATGCCGGCTGCATCCTGGCGAGCGTGCAGGATGCGGCGGCAGCGGCCGACCGCCTGTTTCCGCTGA
GCCTGGCCGCGGAAGGCAGCTGCACCATCGGCGGCAACCTGGCGACCAATGCCGGCGGCACGGCCGTGCTGCGCTACGGC
AACGCGCGCGAACTGTGCCTGGGCGTGGAGGCCGTGCTGCCCGACGGCGCGCTGTGGAACGGCCTGCGCGGCCTGCGCAA
GGACAACACCGGCTACGATCTGCGCGACCTGCTGATCGGTGCGGAAGGCACGCTGGGCATCATCACCGGCGCGACGCTGA
AACTGTTTCCGCAGCCACGCGCGCAGGTGACGGCCCTGGCTGCATTGGCGTCACCGCGGCAAGCGCTGGCATTCCTGTCG
CTGGCGCAAAGCCATGCGGGCACGCTGCTGACGGGGTTCGAGCTGATGTCGGCGTTCTGCCTGGCGCTGGTGCGCAAGCA
CTACCCGCAGTTGCGCGTGCCATTCAGCCAGGCGTATCCGCAGTACGTCCTGCTCGAACTGTCGGACCTGGAAAGCGAAG
CGCACGCGCGCGGCGTGTTCGAAACCCTGATGGAAGACGCGCTGGCGCGCGAGGTGATCCTGGACGCCGCCGTCGCGGAA
TCCGTCGCCCAGTCGCGCGCGCTGTGGGATCTGCGCGAGCACATCCCGCTCGCCCAGGCCGACGAAGGCAAGAACATCAA
GCACGACATCGCCGTGCCGATCTCGCGCATCGCCGACTTCATCGACTTGACCGACCGCGCGCTGGCGGCCGCCTACCCCG
GCATCCGCATGGTGACCTTCGGCCACCTGGGCGACGGCAACCTGCACTACAACGTGTCGCCGCCGGCCGGCCAGGATCAC
GAGACCTTCCTGGCCAACCAGCCCCGCATCAACCGCATCGTGCACGACAGCGTGCACGCGCACGGCGGCTCGATCTCGGC
CGAGCACGGCATCGGCCAGCTCAAGCGCGAGGACAACGCCCGCTACAAGAGCCCGGTTGAATTGGCCGCCATGCGCGCGA
TCAAGCAGGCGCTCGATCCGCGCGGGCTGATGAATCCGGGCAAGGTGCTATAG

Upstream 100 bases:

>100_bases
GCTCAGCCTGGTGTTCTTCTTCGCCACCATCTTCTACCTGCGTCCGTTCAAGCGCGCGGCCAAGGCGCGCGCCCGGCACG
ACGCCTGACCCTCGCCCGCC

Downstream 100 bases:

>100_bases
CGCGCTCGCTATAGATAGCCGAAGTGGCGAGCGGCCAGATTGAGCAGCGCGAAGACAACGGCCGAGGCCAGCAGCCACAG
TAGCAGGCGCGGCACGCCGC

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MTHDAFLQACTDAIGGAHVLTAPEDQAPYLTDWRKRFTGRARAVLRPADPEQVAALVRLCAGHGVPIVPQGGNTGLCGGA
TPDAAGTAVVISLQRLQRVRAVDPINNTITVDAGCILASVQDAAAAADRLFPLSLAAEGSCTIGGNLATNAGGTAVLRYG
NARELCLGVEAVLPDGALWNGLRGLRKDNTGYDLRDLLIGAEGTLGIITGATLKLFPQPRAQVTALAALASPRQALAFLS
LAQSHAGTLLTGFELMSAFCLALVRKHYPQLRVPFSQAYPQYVLLELSDLESEAHARGVFETLMEDALAREVILDAAVAE
SVAQSRALWDLREHIPLAQADEGKNIKHDIAVPISRIADFIDLTDRALAAAYPGIRMVTFGHLGDGNLHYNVSPPAGQDH
ETFLANQPRINRIVHDSVHAHGGSISAEHGIGQLKREDNARYKSPVELAAMRAIKQALDPRGLMNPGKVL

Sequences:

>Translated_470_residues
MTHDAFLQACTDAIGGAHVLTAPEDQAPYLTDWRKRFTGRARAVLRPADPEQVAALVRLCAGHGVPIVPQGGNTGLCGGA
TPDAAGTAVVISLQRLQRVRAVDPINNTITVDAGCILASVQDAAAAADRLFPLSLAAEGSCTIGGNLATNAGGTAVLRYG
NARELCLGVEAVLPDGALWNGLRGLRKDNTGYDLRDLLIGAEGTLGIITGATLKLFPQPRAQVTALAALASPRQALAFLS
LAQSHAGTLLTGFELMSAFCLALVRKHYPQLRVPFSQAYPQYVLLELSDLESEAHARGVFETLMEDALAREVILDAAVAE
SVAQSRALWDLREHIPLAQADEGKNIKHDIAVPISRIADFIDLTDRALAAAYPGIRMVTFGHLGDGNLHYNVSPPAGQDH
ETFLANQPRINRIVHDSVHAHGGSISAEHGIGQLKREDNARYKSPVELAAMRAIKQALDPRGLMNPGKVL
>Mature_469_residues
THDAFLQACTDAIGGAHVLTAPEDQAPYLTDWRKRFTGRARAVLRPADPEQVAALVRLCAGHGVPIVPQGGNTGLCGGAT
PDAAGTAVVISLQRLQRVRAVDPINNTITVDAGCILASVQDAAAAADRLFPLSLAAEGSCTIGGNLATNAGGTAVLRYGN
ARELCLGVEAVLPDGALWNGLRGLRKDNTGYDLRDLLIGAEGTLGIITGATLKLFPQPRAQVTALAALASPRQALAFLSL
AQSHAGTLLTGFELMSAFCLALVRKHYPQLRVPFSQAYPQYVLLELSDLESEAHARGVFETLMEDALAREVILDAAVAES
VAQSRALWDLREHIPLAQADEGKNIKHDIAVPISRIADFIDLTDRALAAAYPGIRMVTFGHLGDGNLHYNVSPPAGQDHE
TFLANQPRINRIVHDSVHAHGGSISAEHGIGQLKREDNARYKSPVELAAMRAIKQALDPRGLMNPGKVL

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI119964728, Length=454, Percent_Identity=38.1057268722467, Blast_Score=282, Evalue=5e-76,
Organism=Homo sapiens, GI37595756, Length=478, Percent_Identity=31.3807531380753, Blast_Score=171, Evalue=9e-43,
Organism=Homo sapiens, GI37595754, Length=501, Percent_Identity=29.940119760479, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI4501993, Length=198, Percent_Identity=30.8080808080808, Blast_Score=86, Evalue=1e-16,
Organism=Escherichia coli, GI1789351, Length=467, Percent_Identity=29.1220556745182, Blast_Score=150, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17534361, Length=452, Percent_Identity=34.2920353982301, Blast_Score=270, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI71992373, Length=438, Percent_Identity=29.4520547945205, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI71992381, Length=438, Percent_Identity=29.4520547945205, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71992392, Length=363, Percent_Identity=29.4765840220386, Blast_Score=127, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI17556096, Length=181, Percent_Identity=25.414364640884, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320023, Length=457, Percent_Identity=34.1356673960613, Blast_Score=306, Evalue=7e-84,
Organism=Saccharomyces cerevisiae, GI6320764, Length=456, Percent_Identity=31.140350877193, Blast_Score=259, Evalue=7e-70,
Organism=Saccharomyces cerevisiae, GI6320027, Length=444, Percent_Identity=28.8288288288288, Blast_Score=161, Evalue=2e-40,
Organism=Drosophila melanogaster, GI18921117, Length=459, Percent_Identity=36.6013071895425, Blast_Score=271, Evalue=6e-73,
Organism=Drosophila melanogaster, GI24639277, Length=459, Percent_Identity=36.6013071895425, Blast_Score=271, Evalue=6e-73,
Organism=Drosophila melanogaster, GI24639275, Length=459, Percent_Identity=36.6013071895425, Blast_Score=271, Evalue=6e-73,
Organism=Drosophila melanogaster, GI24653753, Length=209, Percent_Identity=27.2727272727273, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR004490
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 49900; Mature: 49768

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00147 ARGINASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHDAFLQACTDAIGGAHVLTAPEDQAPYLTDWRKRFTGRARAVLRPADPEQVAALVRLC
CCHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHCCCHHEEECCCCHHHHHHHHHHH
AGHGVPIVPQGGNTGLCGGATPDAAGTAVVISLQRLQRVRAVDPINNTITVDAGCILASV
HCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHH
QDAAAAADRLFPLSLAAEGSCTIGGNLATNAGGTAVLRYGNARELCLGVEAVLPDGALWN
HHHHHHHHHCEEEEEECCCCEEECCCEECCCCCCEEEEECCCHHHHEEHHHHCCCCHHHH
GLRGLRKDNTGYDLRDLLIGAEGTLGIITGATLKLFPQPRAQVTALAALASPRQALAFLS
HHHHHCCCCCCCCHHHHHCCCCCCEEEEECCEEEECCCCHHHHHHHHHHHCHHHHHHHHH
LAQSHAGTLLTGFELMSAFCLALVRKHYPQLRVPFSQAYPQYVLLELSDLESEAHARGVF
HHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEECCHHHCCCCEEEEEEHHCCHHHHHHHHH
ETLMEDALAREVILDAAVAESVAQSRALWDLREHIPLAQADEGKNIKHDIAVPISRIADF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCHHHHHHH
IDLTDRALAAAYPGIRMVTFGHLGDGNLHYNVSPPAGQDHETFLANQPRINRIVHDSVHA
HHHHHHHHHHHCCCEEEEEEEECCCCEEEEECCCCCCCCCCHHCCCCCHHHHHHHHHHHC
HGGSISAEHGIGQLKREDNARYKSPVELAAMRAIKQALDPRGLMNPGKVL
CCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
THDAFLQACTDAIGGAHVLTAPEDQAPYLTDWRKRFTGRARAVLRPADPEQVAALVRLC
CHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHCCCHHEEECCCCHHHHHHHHHHH
AGHGVPIVPQGGNTGLCGGATPDAAGTAVVISLQRLQRVRAVDPINNTITVDAGCILASV
HCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHH
QDAAAAADRLFPLSLAAEGSCTIGGNLATNAGGTAVLRYGNARELCLGVEAVLPDGALWN
HHHHHHHHHCEEEEEECCCCEEECCCEECCCCCCEEEEECCCHHHHEEHHHHCCCCHHHH
GLRGLRKDNTGYDLRDLLIGAEGTLGIITGATLKLFPQPRAQVTALAALASPRQALAFLS
HHHHHCCCCCCCCHHHHHCCCCCCEEEEECCEEEECCCCHHHHHHHHHHHCHHHHHHHHH
LAQSHAGTLLTGFELMSAFCLALVRKHYPQLRVPFSQAYPQYVLLELSDLESEAHARGVF
HHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEECCHHHCCCCEEEEEEHHCCHHHHHHHHH
ETLMEDALAREVILDAAVAESVAQSRALWDLREHIPLAQADEGKNIKHDIAVPISRIADF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCHHHHHHH
IDLTDRALAAAYPGIRMVTFGHLGDGNLHYNVSPPAGQDHETFLANQPRINRIVHDSVHA
HHHHHHHHHHHCCCEEEEEEEECCCCEEEEECCCCCCCCCCHHCCCCCHHHHHHHHHHHC
HGGSISAEHGIGQLKREDNARYKSPVELAAMRAIKQALDPRGLMNPGKVL
CCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]