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The map label for this gene is glmM [H]

Identifier: 17546247

GI number: 17546247

Start: 1631828

End: 1633171

Strand: Direct

Name: glmM [H]

Synonym: RSc1528

Alternate gene names: 17546247

Gene position: 1631828-1633171 (Clockwise)

Preceding gene: 17546246

Following gene: 17546248

Centisome position: 43.91

GC content: 67.41

Gene sequence:

>1344_bases
ATGTCCAGGAAGTATTTCGGCACCGACGGCATCCGCGGGCGCGTGGGCGAAAGCCCGATCACGCCCGACTTCGTGCTGCG
CCTCGGCTACGCGGCGGGCCGCGTGCTGGCGCATGGCAGCGAAGCGCATGGCCACGGCCGGCCCACCGTGCTGATCGGTA
AGGACACGCGCCTGTCCGGCTACATGCTGGAAGCCGCCCTGGAGGCGGGCTTCACCGCCGCCGGCGTGGACGTGCTGATG
AGCGGGCCGTTGCCGACGCCCGGTGTCGCGTATCTCACGCGGGCGCTGCGCCTGTCCGCGGGCGTGGTGATTTCGGCATC
GCACAATCCGTATTACGACAACGGGATCAAGTTCTTCTCGGCCACCGGCGACAAGCTGCCCGATGAAACCGAGTCGCAGA
TCGAGGCCGAGCTCGAAAAGCCGATGGTGTATGCGGCGTCCGATGCGCTGGGCCGCGCCCGCCGCATCGACGATGCCGCC
GGCCGCTACATCGAGTTCTGCAAGAGCACCTTCCCCAACGATCTGAACCTGTTCGGCATGAAGATCGTGCTGGACAGCGC
GCACGGCGCGGCGTATCACATCGCGCCGCACGTGTTCCATGAGCTGGGTGCCGAAGTGGTCTCGATCGGCAACCAGCCGA
ACGGGCGCAACATCAATGACGGCTATGGCGCCACCGAGCCCGCCAAGCTGATCGAGGCGACCCGCCAGCACGGCGCCGAC
CTCGGTCTGGCGTTTGATGGCGATGCCGACCGCCTGCAGGTGGTCGACCGGAACGGTCGCCTGTATAACGGCGATGAACT
GCTGTACGTGATGGTGCAGGCCCGCCGCGCGGCCGGCCAGGCCGTGCCGGGTGCCGTCGGCACGCTGATGACCAACCTGG
CGGTGGAACTGGCGCTGAAGGCGCAGGGCGTCGAATTCGTGCGCGCCAAGGTGGGCGACCGCTATGTGCTGGAAGAGTTG
AAGAAACACGGCTGGCTGCTGGGCGGCGAGGGCTCTGGCCATCTGCTGTGCCTGGACAAGCACAGCACCGGCGACGGCAT
CATCTCCGCGCTGCAGGTGCTGGCGGCACTGCGCCGCAGCGGCCAGACGCTGGAGCAGGTGCTCGATGGCGTGCATCTGT
TCCCGCAGAAGCTGATCAACGTGCGGGTCGAGAAGGGTTTCGACTGGAAAGCGCACGCGGCCTTGCAGGCGGCGTTGAAG
GTGAGCGAGGCTGAGCTGAACGGCAAGGGGCGGGTCCTGATCCGCCCGTCGGGAACCGAGCCGGTCGTGCGCGTGATGGT
CGAGGCACAGGACGCGGCCCTCGCGACCAAGTACGCAGAGCAGCTCGCGGCAACGCTCCAGTGA

Upstream 100 bases:

>100_bases
GGCCGGCCTCGCGCGATCGGGGTCGGGTGAACAGACGATTGTCCGGCCCAGTCCGGCGACTTACAAACAAAAGAACCTCT
CTCTTCAGGAGTGACACGCA

Downstream 100 bases:

>100_bases
GCGCACGCGACGTGCCCAACCAATAAGCGGCGGAAACGCCGCTTTTTTTGTGTCCAACGGTCGACATTTCGGCGATTTGA
GCGTGTTGTGAGAAGTTTTC

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MSRKYFGTDGIRGRVGESPITPDFVLRLGYAAGRVLAHGSEAHGHGRPTVLIGKDTRLSGYMLEAALEAGFTAAGVDVLM
SGPLPTPGVAYLTRALRLSAGVVISASHNPYYDNGIKFFSATGDKLPDETESQIEAELEKPMVYAASDALGRARRIDDAA
GRYIEFCKSTFPNDLNLFGMKIVLDSAHGAAYHIAPHVFHELGAEVVSIGNQPNGRNINDGYGATEPAKLIEATRQHGAD
LGLAFDGDADRLQVVDRNGRLYNGDELLYVMVQARRAAGQAVPGAVGTLMTNLAVELALKAQGVEFVRAKVGDRYVLEEL
KKHGWLLGGEGSGHLLCLDKHSTGDGIISALQVLAALRRSGQTLEQVLDGVHLFPQKLINVRVEKGFDWKAHAALQAALK
VSEAELNGKGRVLIRPSGTEPVVRVMVEAQDAALATKYAEQLAATLQ

Sequences:

>Translated_447_residues
MSRKYFGTDGIRGRVGESPITPDFVLRLGYAAGRVLAHGSEAHGHGRPTVLIGKDTRLSGYMLEAALEAGFTAAGVDVLM
SGPLPTPGVAYLTRALRLSAGVVISASHNPYYDNGIKFFSATGDKLPDETESQIEAELEKPMVYAASDALGRARRIDDAA
GRYIEFCKSTFPNDLNLFGMKIVLDSAHGAAYHIAPHVFHELGAEVVSIGNQPNGRNINDGYGATEPAKLIEATRQHGAD
LGLAFDGDADRLQVVDRNGRLYNGDELLYVMVQARRAAGQAVPGAVGTLMTNLAVELALKAQGVEFVRAKVGDRYVLEEL
KKHGWLLGGEGSGHLLCLDKHSTGDGIISALQVLAALRRSGQTLEQVLDGVHLFPQKLINVRVEKGFDWKAHAALQAALK
VSEAELNGKGRVLIRPSGTEPVVRVMVEAQDAALATKYAEQLAATLQ
>Mature_446_residues
SRKYFGTDGIRGRVGESPITPDFVLRLGYAAGRVLAHGSEAHGHGRPTVLIGKDTRLSGYMLEAALEAGFTAAGVDVLMS
GPLPTPGVAYLTRALRLSAGVVISASHNPYYDNGIKFFSATGDKLPDETESQIEAELEKPMVYAASDALGRARRIDDAAG
RYIEFCKSTFPNDLNLFGMKIVLDSAHGAAYHIAPHVFHELGAEVVSIGNQPNGRNINDGYGATEPAKLIEATRQHGADL
GLAFDGDADRLQVVDRNGRLYNGDELLYVMVQARRAAGQAVPGAVGTLMTNLAVELALKAQGVEFVRAKVGDRYVLEELK
KHGWLLGGEGSGHLLCLDKHSTGDGIISALQVLAALRRSGQTLEQVLDGVHLFPQKLINVRVEKGFDWKAHAALQAALKV
SEAELNGKGRVLIRPSGTEPVVRVMVEAQDAALATKYAEQLAATLQ

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1789566, Length=447, Percent_Identity=56.3758389261745, Blast_Score=488, Evalue=1e-139,
Organism=Escherichia coli, GI1788361, Length=456, Percent_Identity=30.2631578947368, Blast_Score=120, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71993870, Length=332, Percent_Identity=25.3012048192771, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71993878, Length=305, Percent_Identity=25.9016393442623, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.10 [H]

Molecular weight: Translated: 47823; Mature: 47692

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRKYFGTDGIRGRVGESPITPDFVLRLGYAAGRVLAHGSEAHGHGRPTVLIGKDTRLSG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCH
YMLEAALEAGFTAAGVDVLMSGPLPTPGVAYLTRALRLSAGVVISASHNPYYDNGIKFFS
HHHHHHHHCCCCHHCCHHEEECCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEE
ATGDKLPDETESQIEAELEKPMVYAASDALGRARRIDDAAGRYIEFCKSTFPNDLNLFGM
CCCCCCCCHHHHHHHHHHHCCEEEEEHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCEEEE
KIVLDSAHGAAYHIAPHVFHELGAEVVSIGNQPNGRNINDGYGATEPAKLIEATRQHGAD
EEEEECCCCCEEEHHHHHHHHHCHHHEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
LGLAFDGDADRLQVVDRNGRLYNGDELLYVMVQARRAAGQAVPGAVGTLMTNLAVELALK
EEEEECCCCCEEEEEECCCCEECCCCEEEHEEHHHHHCCCCCCHHHHHHHHHHHHHHHHH
AQGVEFVRAKVGDRYVLEELKKHGWLLGGEGSGHLLCLDKHSTGDGIISALQVLAALRRS
HCCHHHHHHHCCCHHHHHHHHHCCCEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHC
GQTLEQVLDGVHLFPQKLINVRVEKGFDWKAHAALQAALKVSEAELNGKGRVLIRPSGTE
CHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHEECCCCEEEEECCCCC
PVVRVMVEAQDAALATKYAEQLAATLQ
HHHHEEHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SRKYFGTDGIRGRVGESPITPDFVLRLGYAAGRVLAHGSEAHGHGRPTVLIGKDTRLSG
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCH
YMLEAALEAGFTAAGVDVLMSGPLPTPGVAYLTRALRLSAGVVISASHNPYYDNGIKFFS
HHHHHHHHCCCCHHCCHHEEECCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEE
ATGDKLPDETESQIEAELEKPMVYAASDALGRARRIDDAAGRYIEFCKSTFPNDLNLFGM
CCCCCCCCHHHHHHHHHHHCCEEEEEHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCEEEE
KIVLDSAHGAAYHIAPHVFHELGAEVVSIGNQPNGRNINDGYGATEPAKLIEATRQHGAD
EEEEECCCCCEEEHHHHHHHHHCHHHEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
LGLAFDGDADRLQVVDRNGRLYNGDELLYVMVQARRAAGQAVPGAVGTLMTNLAVELALK
EEEEECCCCCEEEEEECCCCEECCCCEEEHEEHHHHHCCCCCCHHHHHHHHHHHHHHHHH
AQGVEFVRAKVGDRYVLEELKKHGWLLGGEGSGHLLCLDKHSTGDGIISALQVLAALRRS
HCCHHHHHHHCCCHHHHHHHHHCCCEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHC
GQTLEQVLDGVHLFPQKLINVRVEKGFDWKAHAALQAALKVSEAELNGKGRVLIRPSGTE
CHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHEECCCCEEEEECCCCC
PVVRVMVEAQDAALATKYAEQLAATLQ
HHHHEEHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA