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The map label for this gene is yeaS [C]

Identifier: 17546239

GI number: 17546239

Start: 1622308

End: 1622970

Strand: Direct

Name: yeaS [C]

Synonym: RSc1520

Alternate gene names: 17546239

Gene position: 1622308-1622970 (Clockwise)

Preceding gene: 17546238

Following gene: 17546240

Centisome position: 43.65

GC content: 66.67

Gene sequence:

>663_bases
ATGTTCGCCCACTTCGGCATCATCGAGTTCTGGACCTTCCTGCTCGGCACGATCTTCATCGTGCTGCTGCCGGGGCCGAA
CTCGATGTACGTGCTGTCGGTGGCGGCCCGCCGCGGTGTGCGCGCAGGCTACCAGGGCGCGTGCGGCGTGTTCCTGGGCG
ATGCCATCCTGATGGTGCTGTCGGCGGCGGGCGTGTCGTCGCTGCTCAAGGCGAGTCCGGTGCTGTTCTACGTCGTGAAG
TCCATCGGCGCGGCGTACCTGGCGTGGATCGGCCTGCAGATGCTGCGCGGCGCGGTGCGCAACTGGCGCGCGCGCAAGGC
GGGCGGGTCGGCCGAGCAGAACGCGGCCCGGGGCGACGAATCGCATCCGTTCAAGAAGGCGCTGGTCATCAGCCTGCTGA
ACCCGAAGGCGATCCTGTTCTTCATCTCGTTCTTCATCCAGTTCGTCGATCCGCACTTCGCGCTGCCGGCGCTGTCGTTC
GTCGTGCTGGGGCTGGTCTGCCAGATCGGCAGCTTCCTGTATCTGACCACCATCATCTTCGTGGGCGCGCGGCTGGCCGC
GGCGTTCCGCGCGCGACGACGCCTGGCTGCCGGCATGAGCAGCGGCGTCGGCGCCATGTTTATCGGCTTTTCCGCCAAGC
TGGCGACGGCCACACTGAATTAA

Upstream 100 bases:

>100_bases
GGCCCGCATGACATCGGCTATCTGTTCGACCGCTTCACCGCGGCGATGGCCGAGCGCAAGCAGTAACGGCAAACGAGAGC
GCATAGCCATGAACGCCTTC

Downstream 100 bases:

>100_bases
TCGAATCGAGCGGGTTATGCCAAAACGTACAGACATCAAAACCATCCTGATCATCGGCGCGGGCCCGATCATCATCGGCC
AGGCGTGTGAATTCGATTAC

Product: leucine export protein LeuE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MFAHFGIIEFWTFLLGTIFIVLLPGPNSMYVLSVAARRGVRAGYQGACGVFLGDAILMVLSAAGVSSLLKASPVLFYVVK
SIGAAYLAWIGLQMLRGAVRNWRARKAGGSAEQNAARGDESHPFKKALVISLLNPKAILFFISFFIQFVDPHFALPALSF
VVLGLVCQIGSFLYLTTIIFVGARLAAAFRARRRLAAGMSSGVGAMFIGFSAKLATATLN

Sequences:

>Translated_220_residues
MFAHFGIIEFWTFLLGTIFIVLLPGPNSMYVLSVAARRGVRAGYQGACGVFLGDAILMVLSAAGVSSLLKASPVLFYVVK
SIGAAYLAWIGLQMLRGAVRNWRARKAGGSAEQNAARGDESHPFKKALVISLLNPKAILFFISFFIQFVDPHFALPALSF
VVLGLVCQIGSFLYLTTIIFVGARLAAAFRARRRLAAGMSSGVGAMFIGFSAKLATATLN
>Mature_220_residues
MFAHFGIIEFWTFLLGTIFIVLLPGPNSMYVLSVAARRGVRAGYQGACGVFLGDAILMVLSAAGVSSLLKASPVLFYVVK
SIGAAYLAWIGLQMLRGAVRNWRARKAGGSAEQNAARGDESHPFKKALVISLLNPKAILFFISFFIQFVDPHFALPALSF
VVLGLVCQIGSFLYLTTIIFVGARLAAAFRARRRLAAGMSSGVGAMFIGFSAKLATATLN

Specific function: Unknown

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI1788099, Length=216, Percent_Identity=42.5925925925926, Blast_Score=190, Evalue=7e-50,
Organism=Escherichia coli, GI48994979, Length=213, Percent_Identity=29.5774647887324, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI48994978, Length=191, Percent_Identity=26.1780104712042, Blast_Score=64, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 23543; Mature: 23543

Theoretical pI: Translated: 11.34; Mature: 11.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFAHFGIIEFWTFLLGTIFIVLLPGPNSMYVLSVAARRGVRAGYQGACGVFLGDAILMVL
CCCHHHHHHHHHHHHHHHHEEEECCCCCEEEEEHHHHHCCCCCCCCCHHHHHHHHHHHHH
SAAGVSSLLKASPVLFYVVKSIGAAYLAWIGLQMLRGAVRNWRARKAGGSAEQNAARGDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCC
SHPFKKALVISLLNPKAILFFISFFIQFVDPHFALPALSFVVLGLVCQIGSFLYLTTIIF
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGARLAAAFRARRRLAAGMSSGVGAMFIGFSAKLATATLN
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFAHFGIIEFWTFLLGTIFIVLLPGPNSMYVLSVAARRGVRAGYQGACGVFLGDAILMVL
CCCHHHHHHHHHHHHHHHHEEEECCCCCEEEEEHHHHHCCCCCCCCCHHHHHHHHHHHHH
SAAGVSSLLKASPVLFYVVKSIGAAYLAWIGLQMLRGAVRNWRARKAGGSAEQNAARGDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCC
SHPFKKALVISLLNPKAILFFISFFIQFVDPHFALPALSFVVLGLVCQIGSFLYLTTIIF
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGARLAAAFRARRRLAAGMSSGVGAMFIGFSAKLATATLN
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8169201; 10984043 [H]