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The map label for this gene is cdsA [H]

Identifier: 17546128

GI number: 17546128

Start: 1508103

End: 1508918

Strand: Direct

Name: cdsA [H]

Synonym: RSc1409

Alternate gene names: 17546128

Gene position: 1508103-1508918 (Clockwise)

Preceding gene: 17546127

Following gene: 17546129

Centisome position: 40.58

GC content: 69.12

Gene sequence:

>816_bases
ATGCTGCTGACTCGCGTGATCACCGCTGTCTGCCTGCTGATTGTCATCCTGCCGATCCTGTTGTTCGCTCCGCCCGCCGG
CCTGACCGGGCTGGTGACGGTGTTTGCCGTGCTGGCGGCCTGGGAATGGGGGCGACTGGTCCGTCTGCCGGGCTGGTGGG
GGCCGGTGCTGTACGCGGCCGTGGCGGTCGTGCTGACGATCGCCTGGCACGACATCCCGGTGCATGGTGACACGCGAGCG
CTGTTCTACGCAGACATGGTTGCTTGGGCGGCGGCCTGGATGCTGCTGGCGGGCGGCGTGCGCGAGCTGACGGGCATGCG
CCGGGCGCTGTTCGCGCTGCTGGGCTGGGTGATCCTGCCCGCGTTCGTGCAAGCGACAATCCAATTGCGCGCTGAGGGGA
TCGCCTTCCTGCTGTCGGTGGCGGTGCTGGTGTGGGCGGCGGACGTGGGGGCGTATTTCGTCGGCAAGGCGATCGGCCGT
CGCAAGCTCGCGCCGAGCATCAGCCCCGGCAAATCATGGGAAGGCGCCATCGGCGGCGCGGTGCTGGTGGGCCTCATTGC
GGTGACTGCCGGGGCCACGCACTGGTTCGCGCCGACCTGGTTCTCGCGCCAGTTCGACCAGCATGGCGCCGTGATCGCAC
TGGCGCTGACCGTCGTGCTGGTGGCCGCCAGCGTCGGCGGAGACCTGTTCGAGTCGCTGCTCAAGCGCCAGGTCGGCATG
AAGGACAGCAGCCGCCTGCTGCCCGGCCATGGCGGGGTGCTCGACCGCATCGACGCACTGCTGCCGGTGCTGCCGCTGGC
TGTATTGTTGACCTGA

Upstream 100 bases:

>100_bases
CGCCTTTGCCTGGTATCGCAACCGCGAGCGGCGCTTTGGCCGTACCAGCGCGCAGCTGGAACCCGGTACTGCCCCCGCAC
TGTCGGCTGGAGCCTGACGC

Downstream 100 bases:

>100_bases
GGCGCTTTCCGGACATGATGCGCATTACCGTTCTTGGCGCCACCGGCTCCATCGGCGACAGCACGCTCGACGTGGTGCGC
CGCCATCCCGACCGTTACCG

Product: phosphatidate cytidylyltransferase transmembrane protein

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MLLTRVITAVCLLIVILPILLFAPPAGLTGLVTVFAVLAAWEWGRLVRLPGWWGPVLYAAVAVVLTIAWHDIPVHGDTRA
LFYADMVAWAAAWMLLAGGVRELTGMRRALFALLGWVILPAFVQATIQLRAEGIAFLLSVAVLVWAADVGAYFVGKAIGR
RKLAPSISPGKSWEGAIGGAVLVGLIAVTAGATHWFAPTWFSRQFDQHGAVIALALTVVLVAASVGGDLFESLLKRQVGM
KDSSRLLPGHGGVLDRIDALLPVLPLAVLLT

Sequences:

>Translated_271_residues
MLLTRVITAVCLLIVILPILLFAPPAGLTGLVTVFAVLAAWEWGRLVRLPGWWGPVLYAAVAVVLTIAWHDIPVHGDTRA
LFYADMVAWAAAWMLLAGGVRELTGMRRALFALLGWVILPAFVQATIQLRAEGIAFLLSVAVLVWAADVGAYFVGKAIGR
RKLAPSISPGKSWEGAIGGAVLVGLIAVTAGATHWFAPTWFSRQFDQHGAVIALALTVVLVAASVGGDLFESLLKRQVGM
KDSSRLLPGHGGVLDRIDALLPVLPLAVLLT
>Mature_271_residues
MLLTRVITAVCLLIVILPILLFAPPAGLTGLVTVFAVLAAWEWGRLVRLPGWWGPVLYAAVAVVLTIAWHDIPVHGDTRA
LFYADMVAWAAAWMLLAGGVRELTGMRRALFALLGWVILPAFVQATIQLRAEGIAFLLSVAVLVWAADVGAYFVGKAIGR
RKLAPSISPGKSWEGAIGGAVLVGLIAVTAGATHWFAPTWFSRQFDQHGAVIALALTVVLVAASVGGDLFESLLKRQVGM
KDSSRLLPGHGGVLDRIDALLPVLPLAVLLT

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=286, Percent_Identity=34.965034965035, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1787677, Length=120, Percent_Identity=35.8333333333333, Blast_Score=82, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 28790; Mature: 28790

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLTRVITAVCLLIVILPILLFAPPAGLTGLVTVFAVLAAWEWGRLVRLPGWWGPVLYAA
CHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHH
VAVVLTIAWHDIPVHGDTRALFYADMVAWAAAWMLLAGGVRELTGMRRALFALLGWVILP
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
AFVQATIQLRAEGIAFLLSVAVLVWAADVGAYFVGKAIGRRKLAPSISPGKSWEGAIGGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
VLVGLIAVTAGATHWFAPTWFSRQFDQHGAVIALALTVVLVAASVGGDLFESLLKRQVGM
HHHHHHHHHHCCCHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCC
KDSSRLLPGHGGVLDRIDALLPVLPLAVLLT
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLLTRVITAVCLLIVILPILLFAPPAGLTGLVTVFAVLAAWEWGRLVRLPGWWGPVLYAA
CHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHH
VAVVLTIAWHDIPVHGDTRALFYADMVAWAAAWMLLAGGVRELTGMRRALFALLGWVILP
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
AFVQATIQLRAEGIAFLLSVAVLVWAADVGAYFVGKAIGRRKLAPSISPGKSWEGAIGGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
VLVGLIAVTAGATHWFAPTWFSRQFDQHGAVIALALTVVLVAASVGGDLFESLLKRQVGM
HHHHHHHHHHCCCHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCC
KDSSRLLPGHGGVLDRIDALLPVLPLAVLLT
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8654980; 10984043 [H]