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The map label for this gene is radA [H]

Identifier: 17546091

GI number: 17546091

Start: 1461787

End: 1463157

Strand: Direct

Name: radA [H]

Synonym: RSc1372

Alternate gene names: 17546091

Gene position: 1461787-1463157 (Clockwise)

Preceding gene: 17546090

Following gene: 17546092

Centisome position: 39.33

GC content: 70.46

Gene sequence:

>1371_bases
TTGGCCAAGAGCAAGACGGTCTATACGTGCACCGAGTGCGGCGGCACGTCGCCGAAATGGGCGGGGCAGTGCCCGCATTG
CCAGCAGTGGAACACGCTGGTGGAAACCGTGGCGCAGCCGGCGTCCGGCGCCGGCGCGCGCTTCCAGTCGCTGGCGGCGA
GCGCCGTGGTGCGCAAGCTGGCGGACATCGACGCCGTGGACGTGCCGCGCTTCTCCAGCGGCATCGACGAATTCGACCGC
GTGCTGGGCGGCGGCCTGGTCGGCGGCGGCGTGGTGCTGATCGGCGGCGATCCGGGCATCGGCAAGTCGACGCTGCTGCT
GCAGGCGCTGTCCAACCTGGCGGCCAGCCGGCGCGTGCTGTATGTGAGCGGCGAGGAGTCCGGCGCGCAGATCGCGCTGC
GGGCGCGGCGCCTGGGCGTCGAAAGCCCGAACCTGGCGCTGCTGGCCGAGATCCAGCTCGAGCGCATCCAGGCCACCATC
GAGGCGGAGAAGCCCGAGGTGGTCGTCATCGACTCCATCCAGACGCTGTACTCGGAGGCGCTGACCTCGGCGCCGGGCTC
GGTGGCCCAGGTGCGCGAATGCGCGGCGCAGCTCACGCGCATCGCCAAGCGGCTGGACGTGACCACCATCCTGGTCGGCC
ACGTGACCAAGGAGGGCGCACTGGCGGGCCCGCGCGTGCTGGAGCACATCGTCGATACGGTGCTGTATTTCGAGGGCGAC
ACGCATTCGGCCTACCGGCTGGTGCGCGCGTTCAAGAACCGCTTCGGCGCGGTCAACGAGCTGGGCGTGTTCGCCATGAC
CGAGCGCGGCCTGCGTGGCGTGGCGAATCCGTCGGCGCTGTTCCTGTCGCAGCACGAGCAGACCGTGCCGGGTTCGTGCG
TGCTGGTGACGCAGGAGGGCACGCGTCCGCTGCTGGTGGAGATCCAGGCGCTGGTGGATGCGGCGGGCGTGCCGAACCCG
CGGCGGCTGGCGGTGGGCCTGGAGCAGAACCGGCTGGCGATGCTGCTGGCGGTGCTGCACCGGCACGCGGGCATTGCCTG
CTTTGACCAGGACGTGTTCCTCAATGCCGTGGGCGGGGTCAAGATCACCGAGCCGGCGGCGGACCTGGCGGTGCTGCTGG
CGATCCATTCGTCGATGCGCAACAAGCCGCTGCCGCGCGGGCTGGTGGTTTTCGGCGAGATCGGGCTGGCCGGCGAGATC
CGTCCGACGCCGCGCGGGCAGGAGCGCCTGAAGGAAGCGGCCAAGCTGGGCTTCTCGATTGCCGTGATCCCCAAGTCGAA
CGCGCCCAAGCAGCCGATCGACGGCCTGCAGGTGATCGCCGTCGAGCGCATCGAGCAGGCGATCGACCGGGTGCGCGGGC
TGGAGGCTTAA

Upstream 100 bases:

>100_bases
ACGCTCGGCAAGGCGGCCTGAGCGCCGCGTTCCCATCACACTGAAAACAAAGCGATCAAGCGGCCGCCCCTGAATGCGGC
GGCCGCGGGCAGGGGGTTGT

Downstream 100 bases:

>100_bases
AATTTTTGAAGCGCCGCCGACGATGTTGTTGAAGGTCTCGGCAGCGCTGCGGTGCGATAATCCGCCAACCTTTCTCACCC
ATCCAACGCCGCCATGCAAG

Product: DNA repair protein RadA

Products: NA

Alternate protein names: DNA repair protein sms homolog [H]

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MAKSKTVYTCTECGGTSPKWAGQCPHCQQWNTLVETVAQPASGAGARFQSLAASAVVRKLADIDAVDVPRFSSGIDEFDR
VLGGGLVGGGVVLIGGDPGIGKSTLLLQALSNLAASRRVLYVSGEESGAQIALRARRLGVESPNLALLAEIQLERIQATI
EAEKPEVVVIDSIQTLYSEALTSAPGSVAQVRECAAQLTRIAKRLDVTTILVGHVTKEGALAGPRVLEHIVDTVLYFEGD
THSAYRLVRAFKNRFGAVNELGVFAMTERGLRGVANPSALFLSQHEQTVPGSCVLVTQEGTRPLLVEIQALVDAAGVPNP
RRLAVGLEQNRLAMLLAVLHRHAGIACFDQDVFLNAVGGVKITEPAADLAVLLAIHSSMRNKPLPRGLVVFGEIGLAGEI
RPTPRGQERLKEAAKLGFSIAVIPKSNAPKQPIDGLQVIAVERIEQAIDRVRGLEA

Sequences:

>Translated_456_residues
MAKSKTVYTCTECGGTSPKWAGQCPHCQQWNTLVETVAQPASGAGARFQSLAASAVVRKLADIDAVDVPRFSSGIDEFDR
VLGGGLVGGGVVLIGGDPGIGKSTLLLQALSNLAASRRVLYVSGEESGAQIALRARRLGVESPNLALLAEIQLERIQATI
EAEKPEVVVIDSIQTLYSEALTSAPGSVAQVRECAAQLTRIAKRLDVTTILVGHVTKEGALAGPRVLEHIVDTVLYFEGD
THSAYRLVRAFKNRFGAVNELGVFAMTERGLRGVANPSALFLSQHEQTVPGSCVLVTQEGTRPLLVEIQALVDAAGVPNP
RRLAVGLEQNRLAMLLAVLHRHAGIACFDQDVFLNAVGGVKITEPAADLAVLLAIHSSMRNKPLPRGLVVFGEIGLAGEI
RPTPRGQERLKEAAKLGFSIAVIPKSNAPKQPIDGLQVIAVERIEQAIDRVRGLEA
>Mature_455_residues
AKSKTVYTCTECGGTSPKWAGQCPHCQQWNTLVETVAQPASGAGARFQSLAASAVVRKLADIDAVDVPRFSSGIDEFDRV
LGGGLVGGGVVLIGGDPGIGKSTLLLQALSNLAASRRVLYVSGEESGAQIALRARRLGVESPNLALLAEIQLERIQATIE
AEKPEVVVIDSIQTLYSEALTSAPGSVAQVRECAAQLTRIAKRLDVTTILVGHVTKEGALAGPRVLEHIVDTVLYFEGDT
HSAYRLVRAFKNRFGAVNELGVFAMTERGLRGVANPSALFLSQHEQTVPGSCVLVTQEGTRPLLVEIQALVDAAGVPNPR
RLAVGLEQNRLAMLLAVLHRHAGIACFDQDVFLNAVGGVKITEPAADLAVLLAIHSSMRNKPLPRGLVVFGEIGLAGEIR
PTPRGQERLKEAAKLGFSIAVIPKSNAPKQPIDGLQVIAVERIEQAIDRVRGLEA

Specific function: May play a role in the repair of endogenous alkylation damage [H]

COG id: COG1066

COG function: function code O; Predicted ATP-dependent serine protease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recA family. RadA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790850, Length=454, Percent_Identity=57.2687224669604, Blast_Score=526, Evalue=1e-150,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014774
- InterPro:   IPR004504
- InterPro:   IPR008269
- InterPro:   IPR020568 [H]

Pfam domain/function: PF06745 KaiC; PF05362 Lon_C [H]

EC number: NA

Molecular weight: Translated: 48370; Mature: 48239

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: PS50162 RECA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKSKTVYTCTECGGTSPKWAGQCPHCQQWNTLVETVAQPASGAGARFQSLAASAVVRKL
CCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
ADIDAVDVPRFSSGIDEFDRVLGGGLVGGGVVLIGGDPGIGKSTLLLQALSNLAASRRVL
HCCCCCCCCCHHCCHHHHHHHHCCCEECCCEEEECCCCCCCHHHHHHHHHHHHHHCCEEE
YVSGEESGAQIALRARRLGVESPNLALLAEIQLERIQATIEAEKPEVVVIDSIQTLYSEA
EEECCCCCCCEEHHHHHCCCCCCCEEEEHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHH
LTSAPGSVAQVRECAAQLTRIAKRLDVTTILVGHVTKEGALAGPRVLEHIVDTVLYFEGD
HHCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHEECCC
THSAYRLVRAFKNRFGAVNELGVFAMTERGLRGVANPSALFLSQHEQTVPGSCVLVTQEG
CHHHHHHHHHHHHHCCCHHHCCHHEEHHHCCCCCCCCHHHEEECCCCCCCCCEEEEECCC
TRPLLVEIQALVDAAGVPNPRRLAVGLEQNRLAMLLAVLHRHAGIACFDQDVFLNAVGGV
CCCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEECCCHHEEECCCC
KITEPAADLAVLLAIHSSMRNKPLPRGLVVFGEIGLAGEIRPTPRGQERLKEAAKLGFSI
EEECCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCEE
AVIPKSNAPKQPIDGLQVIAVERIEQAIDRVRGLEA
EEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AKSKTVYTCTECGGTSPKWAGQCPHCQQWNTLVETVAQPASGAGARFQSLAASAVVRKL
CCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
ADIDAVDVPRFSSGIDEFDRVLGGGLVGGGVVLIGGDPGIGKSTLLLQALSNLAASRRVL
HCCCCCCCCCHHCCHHHHHHHHCCCEECCCEEEECCCCCCCHHHHHHHHHHHHHHCCEEE
YVSGEESGAQIALRARRLGVESPNLALLAEIQLERIQATIEAEKPEVVVIDSIQTLYSEA
EEECCCCCCCEEHHHHHCCCCCCCEEEEHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHH
LTSAPGSVAQVRECAAQLTRIAKRLDVTTILVGHVTKEGALAGPRVLEHIVDTVLYFEGD
HHCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHEECCC
THSAYRLVRAFKNRFGAVNELGVFAMTERGLRGVANPSALFLSQHEQTVPGSCVLVTQEG
CHHHHHHHHHHHHHCCCHHHCCHHEEHHHCCCCCCCCHHHEEECCCCCCCCCEEEEECCC
TRPLLVEIQALVDAAGVPNPRRLAVGLEQNRLAMLLAVLHRHAGIACFDQDVFLNAVGGV
CCCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEECCCHHEEECCCC
KITEPAADLAVLLAIHSSMRNKPLPRGLVVFGEIGLAGEIRPTPRGQERLKEAAKLGFSI
EEECCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCEE
AVIPKSNAPKQPIDGLQVIAVERIEQAIDRVRGLEA
EEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]