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The map label for this gene is dsbB

Identifier: 17546092

GI number: 17546092

Start: 1463251

End: 1463730

Strand: Direct

Name: dsbB

Synonym: RSc1373

Alternate gene names: 17546092

Gene position: 1463251-1463730 (Clockwise)

Preceding gene: 17546091

Following gene: 17546093

Centisome position: 39.37

GC content: 67.92

Gene sequence:

>480_bases
ATGCAAGCCAATTCGCGCGCCTTCTTCCTGCTCATTGCCGTGATCGCCTTCGGGCTGGTCGGGTATGCGCTGTACCTGCA
GCACGTGGAGGGCCTGCAGCCGTGTCCGCTGTGCGTGCTGCAGCGGTTCGCCTTCGTCGGCATCGGGGTGTTCTCGCTGC
TGGCGGCGCTGTCGTCGGCCACGCGGCTGCTGTGGCACGGGCTGGGGATGCTGTCGGGGCTGGGCGGCATCTTCGTGGCG
GGGTATCACGTGTCGCTGCTGCTGAACCCGAAGGCGAGCTGCGGCATCGACCCGATCGAGAACTGGGTCAACGCCTTGCC
GACCGCCAAATGGCTGCCGCAGGTGTTCGAGTCCGATGGCCTGTGCACGGCGCCGCTGCCGCCGGTGCTGGGCGTGTCGA
TCCCGCTGTGGTCGCTGATCTGGATGGTGATCCTGGCGCTGACGCTGGTGGTGGCGATGATCCGCCGCGAGCGCCGCTGA

Upstream 100 bases:

>100_bases
GGCTTAAAATTTTTGAAGCGCCGCCGACGATGTTGTTGAAGGTCTCGGCAGCGCTGCGGTGCGATAATCCGCCAACCTTT
CTCACCCATCCAACGCCGCC

Downstream 100 bases:

>100_bases
GCGGCCGCCATGCCGGTGCATCGCGTCCTGGTCAGCGCCTGCCTGCTGGGGCAGCCGGTGCGCTACGACGGCGGTACGGT
GATCGTCGAGGGGGGCATCC

Product: disulfide bond formation protein B

Products: NA

Alternate protein names: Disulfide oxidoreductase

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MQANSRAFFLLIAVIAFGLVGYALYLQHVEGLQPCPLCVLQRFAFVGIGVFSLLAALSSATRLLWHGLGMLSGLGGIFVA
GYHVSLLLNPKASCGIDPIENWVNALPTAKWLPQVFESDGLCTAPLPPVLGVSIPLWSLIWMVILALTLVVAMIRRERR

Sequences:

>Translated_159_residues
MQANSRAFFLLIAVIAFGLVGYALYLQHVEGLQPCPLCVLQRFAFVGIGVFSLLAALSSATRLLWHGLGMLSGLGGIFVA
GYHVSLLLNPKASCGIDPIENWVNALPTAKWLPQVFESDGLCTAPLPPVLGVSIPLWSLIWMVILALTLVVAMIRRERR
>Mature_159_residues
MQANSRAFFLLIAVIAFGLVGYALYLQHVEGLQPCPLCVLQRFAFVGIGVFSLLAALSSATRLLWHGLGMLSGLGGIFVA
GYHVSLLLNPKASCGIDPIENWVNALPTAKWLPQVFESDGLCTAPLPPVLGVSIPLWSLIWMVILALTLVVAMIRRERR

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein

COG id: COG1495

COG function: function code O; Disulfide bond formation protein DsbB

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbB family

Homologues:

Organism=Escherichia coli, GI1787433, Length=162, Percent_Identity=30.2469135802469, Blast_Score=68, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DSBB_RALSO (Q8XZM2)

Other databases:

- EMBL:   AL646052
- RefSeq:   NP_519494.1
- ProteinModelPortal:   Q8XZM2
- SMR:   Q8XZM2
- GeneID:   1220197
- GenomeReviews:   AL646052_GR
- KEGG:   rso:RSc1373
- NMPDR:   fig|267608.1.peg.1373
- HOGENOM:   HBG637909
- OMA:   CILQRYA
- ProtClustDB:   PRK02110
- BioCyc:   RSOL267608:RSC1373-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_00286
- InterPro:   IPR003752
- InterPro:   IPR022920

Pfam domain/function: PF02600 DsbB

EC number: NA

Molecular weight: Translated: 17241; Mature: 17241

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xd28f9a0)-; HASH(0x47c688a8)-; HASH(0xd3551c0)-; HASH(0x47b458d8)-;

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQANSRAFFLLIAVIAFGLVGYALYLQHVEGLQPCPLCVLQRFAFVGIGVFSLLAALSSA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TRLLWHGLGMLSGLGGIFVAGYHVSLLLNPKASCGIDPIENWVNALPTAKWLPQVFESDG
HHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCC
LCTAPLPPVLGVSIPLWSLIWMVILALTLVVAMIRRERR
CCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MQANSRAFFLLIAVIAFGLVGYALYLQHVEGLQPCPLCVLQRFAFVGIGVFSLLAALSSA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TRLLWHGLGMLSGLGGIFVAGYHVSLLLNPKASCGIDPIENWVNALPTAKWLPQVFESDG
HHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCC
LCTAPLPPVLGVSIPLWSLIWMVILALTLVVAMIRRERR
CCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11823852